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AADRQQDSVDTWAVEIVTRLGDLMTSLVDTVEAEVVSEVGELREDALLTRLLHDSIRANIETVFSAIRHG IRIENVEPPTAALEHARRLAQREVSVNSLVRSYRLGHKAVLDVARGQVRALKLDQGLSLDVFGRIEQVTF GYVDHITQEVVNTYQSEHDRWTENRNSLRALRVREVLDGAQLDVDAMTTEIRYPLNLIHLATVMWFDGPA LGNELAIMQRVIRQFGQSVGASASPLFIPVDRLTGWAWVPLTTDTARNAVTEIREFARERTDIPWIAVGD PLPHVAGFRRSHWQARDARSVAIVLGSNAHRVTAAGDPGLSMAGLLGRNIEDAAAWVGQILGPLASQTDS DERLRETLRAFLRSGSSFKAAAEELHLHHNSVKYRVQRAIKRRGRPLTDDRLDVEVALLLCHWYGAAVLG *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1603 | - | - | 100% (421) | hypothetical protein MMAR_1603 |
| M. marinum M | MMAR_1582 | - | e-116 | 50.72% (414) | hypothetical protein MMAR_1582 |
| M. marinum M | MMAR_1323 | - | 6e-97 | 43.83% (413) | hypothetical protein MMAR_1323 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1464 | - | 6e-40 | 31.14% (411) | hypothetical protein Mb1464 |
| M. gilvum PYR-GCK | Mflv_4621 | - | 3e-96 | 44.17% (403) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1429 | - | 6e-40 | 31.14% (411) | hypothetical protein Rv1429 |
| M. leprae Br4923 | MLBr_01052 | - | 2e-18 | 26.64% (274) | hypothetical protein MLBr_01052 |
| M. abscessus ATCC 19977 | MAB_2657c | - | 9e-13 | 22.68% (269) | hypothetical protein MAB_2657c |
| M. avium 104 | MAV_2195 | - | 3e-06 | 43.28% (67) | hypothetical protein MAV_2195 |
| M. smegmatis MC2 155 | MSMEG_1456 | - | 3e-07 | 27.71% (166) | hypothetical protein MSMEG_1456 |
| M. thermoresistible (build 8) | TH_2938 | - | 1e-113 | 53.89% (373) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3434 | - | 0.0 | 99.52% (421) | hypothetical protein MUL_3434 |
| M. vanbaalenii PYR-1 | Mvan_3753 | - | 8e-06 | 30.95% (126) | hypothetical protein Mvan_3753 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1603|M.marinum_M -----------------------------------------MAADRQQDS
MUL_3434|M.ulcerans_Agy99 -----------------------------------------MAADRQQDS
TH_2938|M.thermoresistible__bu --------------------------------------------------
Mflv_4621|M.gilvum_PYR-GCK ----------------------------------------MLDSSEVQDT
Mb1464|M.bovis_AF2122/97 ----------------------------------------------MAEA
Rv1429|M.tuberculosis_H37Rv ----------------------------------------------MAEA
MLBr_01052|M.leprae_Br4923 -----------------------------------------MARQHPSPR
MAB_2657c|M.abscessus_ATCC_199 -------------------------MNEGSERVHTQSMTPDQLWPDASEP
MAV_2195|M.avium_104 --------------------------------------MNDNPFAGPFAK
Mvan_3753|M.vanbaalenii_PYR-1 --------------------------------------MTDNRFIP----
MSMEG_1456|M.smegmatis_MC2_155 MTAPPIDSGRMTVRGLLDESLMAGSRIVAGEDLLDEELTWVLPLNEVLSQ
MMAR_1603|M.marinum_M VDTWAVEIVTRLGDLMTSLVDTVEAEVVSEV-------------------
MUL_3434|M.ulcerans_Agy99 VDTWAVEIVTRLGDLMTSLVDTVEAEVVSEV-------------------
TH_2938|M.thermoresistible__bu ----------------------VGYGPGSRQ-------------------
Mflv_4621|M.gilvum_PYR-GCK PGHAVHHLFRDLGDLVRELPESIHGLLIEQV-------------------
Mb1464|M.bovis_AF2122/97 GGGPISVIARHMQLIRDDFISELFDKMKAEI-------------------
Rv1429|M.tuberculosis_H37Rv GGGPISVIARHMQLIRDDFISELFDKMKAEI-------------------
MLBr_01052|M.leprae_Br4923 VRELIREGARIALNPTQEWIDQLDRATFAAN-------------------
MAB_2657c|M.abscessus_ATCC_199 VRRLIRELAEKMLARSGEVAGDLTAASLEDPR------------------
MAV_2195|M.avium_104 HPRSPLETLDTVPESVLRRLKQYSGRLATEAV------------------
Mvan_3753|M.vanbaalenii_PYR-1 -PRSTVEVLENVPESTLRRLKQYSGRLATQAV------------------
MSMEG_1456|M.smegmatis_MC2_155 HDRLDAVAVYARPESLTARASTLSALAARGATTLLVDGVAPPDLGGLPAG
MMAR_1603|M.marinum_M ----------------GELREDALLTRLLHDSIRANIETVFSA-IRHGIR
MUL_3434|M.ulcerans_Agy99 ----------------GELREDALLTRLLHDSIRANIETVFSA-IRHGIR
TH_2938|M.thermoresistible__bu ----------------GSGCR--QLLELLRDSVEGNIDTIFSA-IQHDIP
Mflv_4621|M.gilvum_PYR-GCK ----------------AELAADQQLKELLSDTVAANVDTWFSV-VRHSIP
Mb1464|M.bovis_AF2122/97 ----------------RGLDYDARMADLWRASITENFVTAVHY-LDRDTP
Rv1429|M.tuberculosis_H37Rv ----------------RGLDYDARMADLWRASITENFVTAVHY-LDRDTP
MLBr_01052|M.leprae_Br4923 ----------------PAIANDPVLAKVVRRASRAHLVHWATANLRDPGA
MAB_2657c|M.abscessus_ATCC_199 ---------------YRTIADDPVIAEVDARLTVSNLKHWLTSNISEPGH
MAV_2195|M.avium_104 ---------------SVMQDRLPFFADLEASQRASVSLVVQTAVVNFAEW
Mvan_3753|M.vanbaalenii_PYR-1 ---------------HAMEERLPFFAELDASQRASVQLVVQTAVVNFAEW
MSMEG_1456|M.smegmatis_MC2_155 LVVVELGIPVGFAALNRLLAERALSQEVHVMRYSTHVHATLAGLFHRGAG
: .
MMAR_1603|M.marinum_M IENVEPPTAALEHARRLAQREV-------------------SVNSLVRSY
MUL_3434|M.ulcerans_Agy99 IENVEPPTAALEHARRLAQREV-------------------SVNSLVRSY
TH_2938|M.thermoresistible__bu IEEVAPPTAALEYARRLARHGV-------------------EPHALLRAY
Mflv_4621|M.gilvum_PYR-GCK FDRMESPTAALEHARRMAQREV-------------------PVNALLRAY
Mb1464|M.bovis_AF2122/97 QSLVEAPAAALAYARAAAQRDI-------------------PLSGLVRAH
Rv1429|M.tuberculosis_H37Rv QSLVEAPAAALAYARAAAQRDI-------------------PLSGLVRAH
MLBr_01052|M.leprae_Br4923 PVPAHLGPEPLTMARDLVRRGR-------------------DVLALD-IY
MAB_2657c|M.abscessus_ATCC_199 RVRPATGSAMRTYARDVVLRGL-------------------TTDDIQ-SW
MAV_2195|M.avium_104 MQDPKSNVRHTAQAFELVPQDL-------------------ARRIALRHS
Mvan_3753|M.vanbaalenii_PYR-1 MRDPRSNVSYTAQAFEVVPQDL-------------------RRRIALRQS
MSMEG_1456|M.smegmatis_MC2_155 LQILVREVSNLARNPAVALDARGHVVAHHGLPPEAVAALADSVSRMLAAD
.
MMAR_1603|M.marinum_M RLGHKAVLDVARGQVRALKLDQGLSLDVFGRIEQVTFGYVDHITQEVVNT
MUL_3434|M.ulcerans_Agy99 RLGHKAVLDVARGQVRALKLDQGLILDVFGRIEQVTFGYVDHITQEVVNT
TH_2938|M.thermoresistible__bu RLGQQKLLDIVLHEIRSLDWEREVSLEFVVGVTNATFGYIDGISQRVVEV
Mflv_4621|M.gilvum_PYR-GCK RLGHQYGLNLIIAGLRSADLPPEEKLALIEHITRVSFRYIDWMSEQVLET
Mb1464|M.bovis_AF2122/97 RLGHARFLEVAMQYVSLLEPADR--VSTIIELVNRSARLVDLVADQLIVA
Rv1429|M.tuberculosis_H37Rv RLGHARFLEVAMQYVSLLEPADR--VSTIIELVNRSARLVDLVADQLIVA
MLBr_01052|M.leprae_Br4923 RVGQYTAWRRWMEIAFTLTSDPQELREILNVSAQSINEYVAATLEAIATH
MAB_2657c|M.abscessus_ATCC_199 RAVQRVGWKWWLAACFQVTDDKEQLCELIEVTSNSLTTFVDDSIAELAEH
MAV_2195|M.avium_104 VEMVRVTMEFFEEVVPLLARSEEQ----LTALTVGVLKYSRDLAFTAATA
Mvan_3753|M.vanbaalenii_PYR-1 VEMVRVTMEFFEEVVPLLARSEDQ----LAAMTAGILRYSRDLAFAAATA
MSMEG_1456|M.smegmatis_MC2_155 LPASERRHDGHDTRTQQVTGPEDSRWTCVASAIRLGKSFEGWVAVLVPTL
.
MMAR_1603|M.marinum_M YQSEHD-----------------------------RWTENRNSLRALRVR
MUL_3434|M.ulcerans_Agy99 YQSEHD-----------------------------RWTENRNSLRALRVR
TH_2938|M.thermoresistible__bu YQQERE-----------------------------RWLENRNSLRAMRVR
Mflv_4621|M.gilvum_PYR-GCK YQTERA-----------------------------EWDERRRSLRAQAIR
Mb1464|M.bovis_AF2122/97 YEHEHD-----------------------------RWLSRRSGLQQQWVS
Rv1429|M.tuberculosis_H37Rv YEHEHD-----------------------------RWLSRRSGLQQQWVS
MLBr_01052|M.leprae_Br4923 MQLERD-----------------------------ELTRSTHAERLEVVD
MAB_2657c|M.abscessus_ATCC_199 VRRVRE-----------------------------ELAGGSQLQRYATVE
MAV_2195|M.avium_104 YADAAE-----------------------------ARGTWDSRMEASVVD
Mvan_3753|M.vanbaalenii_PYR-1 YADQAE-----------------------------ARGAWDTRMEANLVD
MSMEG_1456|M.smegmatis_MC2_155 APDHADGPSKHDLARHEVLTEQATAIIGSEMLRQRSVDEAEERARGDFVQ
. :
MMAR_1603|M.marinum_M EVLDGAQ-LDVDAMTTEIRYPLNLIHLATVMWF--DGPALGNELAIMQR-
MUL_3434|M.ulcerans_Agy99 EVLDGAQ-LDVDAMTTEIRYPLNLIHLATVMWF--DGPALGNELAIMQR-
TH_2938|M.thermoresistible__bu ELLDGGE-VDVDTASATVGYPLRRTHLAVCVWTP-DGSAGDNELDRLQR-
Mflv_4621|M.gilvum_PYR-GCK DILNGRD-VDLTEASSAMRYFLGATHVALMVWLDRDAGADTDEFIAMER-
Mb1464|M.bovis_AF2122/97 ELLADTP-VDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVR
Rv1429|M.tuberculosis_H37Rv ELLADTP-VDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVR
MLBr_01052|M.leprae_Br4923 LILEGAP-VTQERAEARLGYRLGLTHTAAVIWSD----DLDGDHGYLDQ-
MAB_2657c|M.abscessus_ATCC_199 LLLQGAD-IAPARAEAQLGYALTGSHIGAVVWVD----SEK-EIAALER-
MAV_2195|M.avium_104 AVVRGDTGPELLSRAAALNWDTTAPATVVVGTPA----PGRDGSTGPGD-
Mvan_3753|M.vanbaalenii_PYR-1 AVVRGGTRPELQSQAAALNWDATAPATVIVGMPR----PDR---------
MSMEG_1456|M.smegmatis_MC2_155 ALVHGSFSSEHDMRARAEHHDIELDARFGVFVAPGVLPRGPDSPTTPMVR
:: .
MMAR_1603|M.marinum_M --------VIRQFGQSVGASASPLFIPVDRLTGWAWVPLTTDTARNAVTE
MUL_3434|M.ulcerans_Agy99 --------VIRQFGQSVGASASPLFIPVDRLTGWAWVPLTTDTARNAVTE
TH_2938|M.thermoresistible__bu --------YVRGLAEALGAPGDSLFIALDRLTGCGWIPLPGDAATGAVAG
Mflv_4621|M.gilvum_PYR-GCK --------FMQHAVSATGAKQS-VYFSIDRLVGCAWMTVHR--PSDYLSQ
Mb1464|M.bovis_AF2122/97 CL------LAGELGPELGPVANSLMVPTDEREARLWFSPAP-TRAFAPSR
Rv1429|M.tuberculosis_H37Rv CL------LAGELGPELGPVANSLMVPTDEREARLWFSPAP-TRAFAPSR
MLBr_01052|M.leprae_Br4923 ---------AAEAFSHVVESTQQLIVVASAATRWVWLADAL---ALDVPE
MAB_2657c|M.abscessus_ATCC_199 ---------ASEQVMRACGADRRLTVVAGTVALWLWIPAKT---TPTVAV
MAV_2195|M.avium_104 ---------SERASQHVRDIAAQHGRAALTDVHGTWLVAIVSGQLSPTDK
Mvan_3753|M.vanbaalenii_PYR-1 ---------AEFAGDDVHEVADRNGRTALSDVHGTWLVAIISGGLSPTDR
MSMEG_1456|M.smegmatis_MC2_155 LARYAAGVAAHPSVHAYVTVIGDVLVVVRTLRGEDAAAMRSEMAEYAEAM
MMAR_1603|M.marinum_M IREFARERTDIPWIAVGDPLPHVAGFRRSHWQARDARSVAIVL-GSNAHR
MUL_3434|M.ulcerans_Agy99 IREFARERTDIPWIAVGDPLPHVAGFRRSHWQARDARSVAIVL-GSNAHR
TH_2938|M.thermoresistible__bu VRRYAAEHPDGPHLALGDPLPGLDGFRRSYRQALRTRAVAVAA-GASAPR
Mflv_4621|M.gilvum_PYR-GCK LRDFVRAQPDGPRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHR
Mb1464|M.bovis_AF2122/97 IRAAFESAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGR
Rv1429|M.tuberculosis_H37Rv IRAAFESAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGR
MLBr_01052|M.leprae_Br4923 VQKALLNLS-KARVAIGTSSAGIEGFRRSHLEALTAQRTLARL--KSHQQ
MAB_2657c|M.abscessus_ATCC_199 LMDSLGRRS-GVRVALGRAATGMAGFRRTHMDAAAAQRLLARL--GSPLS
MAV_2195|M.avium_104 FLGDLLEAFSDGPVVVGPTAPMLTAAYHSASEAISGMNAVGGWRGAPRP-
Mvan_3753|M.vanbaalenii_PYR-1 FLSELMTVFADGPVVIGPTAPTLGAAHRSATEAIAGMNAVAGWAGAPRP-
MSMEG_1456|M.smegmatis_MC2_155 SGELQRRRGLPAPVAYGRPALGAGEVRESYREARVALGIARRLHRTGATS
: * : :*
MMAR_1603|M.marinum_M VTAAGDPGLSMAGLLGRNIEDAAAWVGQILGPLASQTDSDERLRETLRAF
MUL_3434|M.ulcerans_Agy99 VTAAGDPGLSMAGLLGRNIEDAAAWVGQILGPLASQTDSDERLRETLRAF
TH_2938|M.thermoresistible__bu VTAAADPGLSAAALLTGDLAEARTWVQEVLGPLSADTKNDARLRETLGVF
Mflv_4621|M.gilvum_PYR-GCK IVAARDPGVALASMLMTDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVF
Mb1464|M.bovis_AF2122/97 VMFYDD--VAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREF
Rv1429|M.tuberculosis_H37Rv VMFYDD--VAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREF
MLBr_01052|M.leprae_Br4923 VAFFAD--VQLVSLITQNPEDAKEFITSTLGDFESAS---PALQQTLLTF
MAB_2657c|M.abscessus_ATCC_199 VVRYED--VHLMDLLSADPASADQFVTDVLGEFQSAS---PVLHQTVLTY
MAV_2195|M.avium_104 ---VLARELLPERALMGDASAIVALHTDVMGPLADAG---PTLIETLDAF
Mvan_3753|M.vanbaalenii_PYR-1 ---VSARELLPERALLGDATAGAALEAEVMRPLSDAG---PALMETLDAY
MSMEG_1456|M.smegmatis_MC2_155 YQQLRG---FTVLAQVAETEDSRQLVRDVLGPLRSSP----DLLETLEAY
: . : : * :*: :
MMAR_1603|M.marinum_M LRSGSSFKAAAEELHLHHNSVKYRVQRAIKRRGRPLTD--DRLDVEVALL
MUL_3434|M.ulcerans_Agy99 LRSGSSFKAAAEELHLHHNSVKYRVQRAIKRRGRPLTA--DRLDVEVALL
TH_2938|M.thermoresistible__bu LRHGSSYTAAADELNLHFNTVKYRVQRAVERRGRPIVP--DRLDVELALL
Mflv_4621|M.gilvum_PYR-GCK LRAGSSFKAAANELQIHANTVKYRVNRALERRGRPIAA--ERLDVEVALL
Mb1464|M.bovis_AF2122/97 LLRNRSYVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALE
Rv1429|M.tuberculosis_H37Rv LLRNRSYVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALE
MLBr_01052|M.leprae_Br4923 INEQCNASRAAKRLFTHRNTLLRRIESAEKLLPRPLDH--TSVHIAVALE
MAB_2657c|M.abscessus_ATCC_199 VEEALNRTSTAERLYTHRNTIDRRLARVDELLPKPFAR--NPIEVAAALT
MAV_2195|M.avium_104 LDSGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPMQPRDAYVLRVAAT
Mvan_3753|M.vanbaalenii_PYR-1 LDSGGAIEACARKLFVHPNTVRYRLKRIADFTGRDPTVPRDAYVLRVASS
MSMEG_1456|M.smegmatis_MC2_155 LSEGGNINATARTLNVHRNTMLAKLDRISRMLGMDVRDPEHQFTVWLAIR
: * : * *:: :: : *
MMAR_1603|M.marinum_M LCHWYGAAVLG-------------------------
MUL_3434|M.ulcerans_Agy99 LCHWYGAAVLG-------------------------
TH_2938|M.thermoresistible__bu ICQWFGAAVLRPQR----------------------
Mflv_4621|M.gilvum_PYR-GCK MCYWLGEVALNPTQALGRS-----------------
Mb1464|M.bovis_AF2122/97 VCRWMAPAVLRAKQ----------------------
Rv1429|M.tuberculosis_H37Rv VCRWMAPAVLRAKQ----------------------
MLBr_01052|M.leprae_Br4923 ALQWRGDQTNTSGPRAGRNDGVPA------------
MAB_2657c|M.abscessus_ATCC_199 LLRVRAGR----------------------------
MAV_2195|M.avium_104 VGQLNYPTHPPSAAGAAMPAVPLPVNGAARGQSGG-
Mvan_3753|M.vanbaalenii_PYR-1 VGRLARQAH-LSAAPAAASAQAIGVASVTSPENLGT
MSMEG_1456|M.smegmatis_MC2_155 LDLLDEVHSAVEREASFR------------------