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NEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLARSGEVAGDLTAASLEDPRYRTIADDPVIAEVD ARLTVSNLKHWLTSNISEPGHRVRPATGSAMRTYARDVVLRGLTTDDIQSWRAVQRVGWKWWLAACFQVT DDKEQLCELIEVTSNSLTTFVDDSIAELAEHVRRVREELAGGSQLQRYATVELLLQGADIAPARAEAQLG YALTGSHIGAVVWVDSEKEIAALERASEQVMRACGADRRLTVVAGTVALWLWIPAKTTPTVAVLMDSLGR RSGVRVALGRAATGMAGFRRTHMDAAAAQRLLARLGSPLSVVRYEDVHLMDLLSADPASADQFVTDVLGE FQSASPVLHQTVLTYVEEALNRTSTAERLYTHRNTIDRRLARVDELLPKPFARNPIEVAAALTLLRVRAG R*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2657c | - | - | 100% (422) | hypothetical protein MAB_2657c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1226c | - | 1e-74 | 36.30% (405) | hypothetical protein Mb1226c |
| M. gilvum PYR-GCK | Mflv_4621 | - | 2e-18 | 23.76% (404) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1194c | - | 1e-74 | 36.30% (405) | hypothetical protein Rv1194c |
| M. leprae Br4923 | MLBr_01052 | - | 8e-71 | 36.43% (398) | hypothetical protein MLBr_01052 |
| M. marinum M | MMAR_1127 | - | 1e-75 | 39.51% (405) | hypothetical protein MMAR_1127 |
| M. avium 104 | MAV_1330 | - | 3e-05 | 22.47% (316) | hypothetical protein MAV_1330 |
| M. smegmatis MC2 155 | MSMEG_6492 | - | 2e-09 | 28.15% (270) | GAF domain-containing protein |
| M. thermoresistible (build 8) | TH_4306 | - | 9e-22 | 29.45% (292) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0944 | - | 4e-73 | 36.07% (402) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1323 | - | 7e-07 | 35.20% (125) | transcriptional regulator, CdaR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1226c|M.bovis_AF2122/97 --------------------------------------------------
Rv1194c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0944|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01052|M.leprae_Br4923 --------------------------------------------------
MMAR_1127|M.marinum_M --------------------------------------------------
MAB_2657c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4621|M.gilvum_PYR-GCK --------------------------------------------------
TH_4306|M.thermoresistible__bu --------------------------------------------------
MAV_1330|M.avium_104 -----------------------------------MAGVGLGQLLLALDA
MSMEG_6492|M.smegmatis_MC2_155 -------MTWLGALRRLSASATAEEDLSHVLAEIAETARSLLGFDFCGVL
Mvan_1323|M.vanbaalenii_PYR-1 MRHDDDRMTVAGLLDESLMSGAHVLTGADRLDQQVHWVLPLSEVMSRHDA
Mb1226c|M.bovis_AF2122/97 ------------------------------MAWQQPSPRIRELIREGARI
Rv1194c|M.tuberculosis_H37Rv ------------------------------MAWQQPSPRIRELIREGARI
MUL_0944|M.ulcerans_Agy99 ------------------------------MPWQRPSSRIRELIREGARR
MLBr_01052|M.leprae_Br4923 ------------------------------MARQHPSPRVRELIREGARI
MMAR_1127|M.marinum_M ------------------------------MLWQGPSPRVGELIRQGAKA
MAB_2657c|M.abscessus_ATCC_199 --------------MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEK
Mflv_4621|M.gilvum_PYR-GCK -------------------------MLDSSEVQDTPGHAVHHLFRDLGDL
TH_4306|M.thermoresistible__bu ------------MSYEGAWMSGLRPRSTPTVAAASPEPAVQWARRVAGDG
MAV_1330|M.avium_104 TMVSLVDAPRGLDQPVASAALIDSDDVRLGLAAAAGSADVFFLLGVGDDE
MSMEG_6492|M.smegmatis_MC2_155 LPDEQSRHLRVRGASGLSSDYVDRVNSDRPLVLHGGSPSSRAFHTAEAVA
Mvan_1323|M.vanbaalenii_PYR-1 LDGVAVYTRPEALLGNGGTLAPLAARGATALLVDGTVPADFPTAAVPADM
Mb1226c|M.bovis_AF2122/97 ALNPSPEWIEELDRATIAAN--------PAIANDPVLAKVV----QTANR
Rv1194c|M.tuberculosis_H37Rv ALNPSPEWIEELDRATIAAN--------PAIANDPVLAKVV----QTANR
MUL_0944|M.ulcerans_Agy99 ALNAGPEWIEELDRETVSAN--------PTIANDPVLAKVV----KRVNR
MLBr_01052|M.leprae_Br4923 ALNPTQEWIDQLDRATFAAN--------PAIANDPVLAKVV----RRASR
MMAR_1127|M.marinum_M VLDGSQQWLDEYDRVTMAAN--------PAIADDPVLAEAT----RRSIR
MAB_2657c|M.abscessus_ATCC_199 MLARSGEVAGDLTAASLEDPRY------RTIADDPVIAEVD----ARLTV
Mflv_4621|M.gilvum_PYR-GCK VR----ELPESIHGLLIEQV--------AELAADQQLKELL----SDTVA
TH_4306|M.thermoresistible__bu PVDWAVEHAYEFALHVLQEI--------PELDGTGGRTRMV----RVGAE
MAV_1330|M.avium_104 ALRWIDTQARDRVPVAVFVKEPSDALVGTAVAAGSAVVAVD----PRARW
MSMEG_6492|M.smegmatis_MC2_155 IRDVTAEPGFELWAGIANEQGYRSMIAVPLVARGEVLGTLNGYYGAVHTY
Mvan_1323|M.vanbaalenii_PYR-1 VVVEMAFPVGFAALNRLLAERALSQEVHAMRYATHVHASLAG-LFHRGAG
Mb1226c|M.bovis_AF2122/97 ANLVYWAAANLRDPGARVPANLG--TEPLRMARDLVRRGLDT-------V
Rv1194c|M.tuberculosis_H37Rv ANLVYWAAANLRDPGARVPANLG--TEPLRMARDLVRRGLDT-------V
MUL_0944|M.ulcerans_Agy99 ANLVHWAAANVRHPGAPVPANLG--GEPLRMARDLVRRGLEA-------L
MLBr_01052|M.leprae_Br4923 AHLVHWATANLRDPGAPVPAHLG--PEPLTMARDLVRRGRDV-------L
MMAR_1127|M.marinum_M SSLIHWAAANVSNPGAPVAPNLG--PEPLSIARDMVRRGLDP-------F
MAB_2657c|M.abscessus_ATCC_199 SNLKHWLTSNISEPGHRVRPATG--SAMRTYARDVVLRGLTT-------D
Mflv_4621|M.gilvum_PYR-GCK ANVDTWFSV-VRHSIPFDRMESP--TAALEHARRMAQREVPVN------A
TH_4306|M.thermoresistible__bu ACVLQVLMLLFDDR---SDVEMP--DEQEQVVRDCVHRKVPLD------R
MAV_1330|M.avium_104 ERLYQLVNHVLEHHGDRADAADDSGTDLFGLAQSLAERIHGMVSIENAQS
MSMEG_6492|M.smegmatis_MC2_155 TRFEVERMTLLANHAAIAVSSARRLDELRALTASLRRQRDALTRSEQIHD
Mvan_1323|M.vanbaalenii_PYR-1 LQLLVREVSNLARNPAMALDARGNVVAHNGFTAETAAALTESILPLLTAD
. . .
Mb1226c|M.bovis_AF2122/97 AFNIYRTGEH--------------------------------------IG
Rv1194c|M.tuberculosis_H37Rv AFNIYRTGEH--------------------------------------IG
MUL_0944|M.ulcerans_Agy99 TLDIYRIGQY--------------------------------------IA
MLBr_01052|M.leprae_Br4923 ALDIYRVGQY--------------------------------------TA
MMAR_1127|M.marinum_M TF---RIAQT--------------------------------------VG
MAB_2657c|M.abscessus_ATCC_199 DIQSWRAVQR--------------------------------------VG
Mflv_4621|M.gilvum_PYR-GCK LLRAYRLGHQ--------------------------------------YG
TH_4306|M.thermoresistible__bu LFSAIRNTHA--------------------------------------WV
MAV_1330|M.avium_104 QVLAYSASND--------------------------------------EA
MSMEG_6492|M.smegmatis_MC2_155 RLLAVTLRSGGLDGIAAVLQGLIGRPILIDDIQHEVLACSVVTTDFPDTT
Mvan_1323|M.vanbaalenii_PYR-1 LPAAARLSAHHDTR---------------------------------VER
Mb1226c|M.bovis_AF2122/97 WRFWMGIAFELTSDPQEL---------------RELLDVSARSVNDFIEA
Rv1194c|M.tuberculosis_H37Rv WRFWMGIAFELTSDPQEL---------------RELLDVSARSVNDFIEA
MUL_0944|M.ulcerans_Agy99 WRLWINIAFDLTSDPQEL---------------HELLDVSAKSVNEFIEA
MLBr_01052|M.leprae_Br4923 WRRWMEIAFTLTSDPQEL---------------REILNVSAQSINEYVAA
MMAR_1127|M.marinum_M WRLWMGVAFGLTSDPDEL---------------RELFEVTYRSISEFVEA
MAB_2657c|M.abscessus_ATCC_199 WKWWLAACFQVTDDKEQL---------------CELIEVTSNSLTTFVDD
Mflv_4621|M.gilvum_PYR-GCK LNLIIAGLRSADLPPEEK---------------LALIEHITRVSFRYIDW
TH_4306|M.thermoresistible__bu TRIFMDACIELAPPSQQV---------------AELRRISS-ITLAVFDR
MAV_1330|M.avium_104 DELRRLSILGRAGPPEHLEWIGQWGIFDALRSGTQVVRVAERPELGLRPR
MSMEG_6492|M.smegmatis_MC2_155 WRAAAEAGTGSSPVPVGQFDGTTYLASAVHLGDEVAARIWFPETSIDLDP
Mvan_1323|M.vanbaalenii_PYR-1 FGAPGGGVWTVISTAIRLG---------KAFEGWVLVVVPSAEPGGHDLA
Mb1226c|M.bovis_AF2122/97 TLTGIAAQVQSEHDE-------LTRSTHAERLEVVGLILDGAPISPERAE
Rv1194c|M.tuberculosis_H37Rv TLTGIAAQVQSEHDE-------LTRSTHAERLEVVGLILDGAPISPERAE
MUL_0944|M.ulcerans_Agy99 TLAGIAAQVQLEHDE-------LTRGNHADRLEVVGHLLEGAPISRERAE
MLBr_01052|M.leprae_Br4923 TLEAIATHMQLERDE-------LTRSTHAERLEVVDLILEGAPVTQERAE
MMAR_1127|M.marinum_M TSAGIAAQMQRERDE-------LARGTHAERREVTALILDGAPISRQRAE
MAB_2657c|M.abscessus_ATCC_199 SIAELAEHVRRVREE-------LAGGSQLQRYATVELLLQGADIAPARAE
Mflv_4621|M.gilvum_PYR-GCK MSEQVLETYQTERAE-------WDERRRSLRAQAIRDILNGRDVDLTEAS
TH_4306|M.thermoresistible__bu YTERADVAYRAEAER-------WFAGDQATREELVQTLLTRDDADTDRIS
MAV_1330|M.avium_104 LAVGIHQPDPDARRPPVFAGTIWVQQGAQPLADDAEQILRGAAVLAARIM
MSMEG_6492|M.smegmatis_MC2_155 IMVRAVEHASIVTALELLRCQTAAEVEQRLRGELLSDVLSSGAALSDRLL
Mvan_1323|M.vanbaalenii_PYR-1 RHIVVTEQATAIIGSEMLRQHSVDEAEERARGDFVQALVHGHFSSEHDMR
::
Mb1226c|M.bovis_AF2122/97 A---KLGYPLS-RAHTAAIIWSDELDGDHS----YLDRAADLFCHAVGS-
Rv1194c|M.tuberculosis_H37Rv A---KLGYPLS-RAHTAAIIWSDELDGDHS----YLDRAADLFCHAVGS-
MUL_0944|M.ulcerans_Agy99 T---RLGYSLI-RAHTAAIIWSDDFDGDHS----NLDRAADAFCHAVGS-
MLBr_01052|M.leprae_Br4923 A---RLGYRLG-LTHTAAVIWSDDLDGDHG----YLDQAAEAFSHVVES-
MMAR_1127|M.marinum_M A---RLGYALN-RTHTAAVIWSDEPDGDLN----RLDRVVDAFGRAADF-
MAB_2657c|M.abscessus_ATCC_199 A---QLGYALT-GSHIGAVVWVDS-EKEIA----ALERASEQVMRACGA-
Mflv_4621|M.gilvum_PYR-GCK S---AMRYFLG-ATHVALMVWLDRDAGADTDEFIAMERFMQHAVSATGA-
TH_4306|M.thermoresistible__bu Q---RLRYPVTGRNHLGVVAWREAGTDAAD----DLAEAAAAWLRAAGA-
MAV_1330|M.avium_104 A---RLAARPSTQARRLQQLLGVTDSETLAP--VDLTAIAAELGLAADG-
MSMEG_6492|M.smegmatis_MC2_155 DRAHRLGHDLT-VPHIAIVGAFTGLDPVAERRAYERSLVLLAKESAAHR-
Mvan_1323|M.vanbaalenii_PYR-1 AR--ADYHEIDIDSVFGVFVAPGAVPRGVDNPAASMVRLARYAANVAPDP
.
Mb1226c|M.bovis_AF2122/97 -TRPLTVVAGAASRWAWVTDAD--GLDIDTVQAAVDNAP-----------
Rv1194c|M.tuberculosis_H37Rv -TRPLTVVAGAASRWAWVTDAD--GLDIDTVQAAVDNAP-----------
MUL_0944|M.ulcerans_Agy99 -SQDLTVVANAATRWVWLAEAT--NLDIDTIEQAVDNAS-----------
MLBr_01052|M.leprae_Br4923 -TQQLIVVASAATRWVWLADAL--ALDVPEVQKALLNLS-----------
MMAR_1127|M.marinum_M -ARPLTVIAGAATRWVWVANAANATLDVEQVEQAVRDVP-----------
MAB_2657c|M.abscessus_ATCC_199 -DRRLTVVAGTVALWLWIPAKT--TPTVAVLMDSLGRRS-----------
Mflv_4621|M.gilvum_PYR-GCK -KQSVYFSIDRLVGCAWMTVHR-PSDYLSQLRDFVRAQPD----------
TH_4306|M.thermoresistible__bu -AEVLVLNRAESAVWAWGATPS----PPRSVPTDWTHSG-----------
MAV_1330|M.avium_104 -CAALVGWAAAEGASRHTRLTDVIALSASAFRHDAHVAGHGSRTYVLLPQ
MSMEG_6492|M.smegmatis_MC2_155 -PKPVVAMHAGTIVMLWPAQDAADAAGAGEVVRQAMRAAS----------
Mvan_1323|M.vanbaalenii_PYR-1 AVRSYVTVLGDVLVVVRSLRGADDTAMRKEMTRYAEAMADELQN------
.
Mb1226c|M.bovis_AF2122/97 -----------------------GARIAIGTTANGVEGFRRSHLEALITQ
Rv1194c|M.tuberculosis_H37Rv -----------------------GARIAIGTTANGVEGFRRSHLEALITQ
MUL_0944|M.ulcerans_Agy99 -----------------------DARIAIGTKASGIEGFRRSHLEALTTQ
MLBr_01052|M.leprae_Br4923 -----------------------KARVAIGTSSAGIEGFRRSHLEALTAQ
MMAR_1127|M.marinum_M -----------------------GARIAIGAAATGIEGFRRSHLEALTTQ
MAB_2657c|M.abscessus_ATCC_199 -----------------------GVRVALGRAATGMAGFRRTHMDAAAAQ
Mflv_4621|M.gilvum_PYR-GCK -----------------------GPRLSVGEPLPGIEGFRRTYRQAEQAR
TH_4306|M.thermoresistible__bu -----------------------GVRIGHGTWHPGLQGFRLTHREARSAE
MAV_1330|M.avium_104 PPNRSVSSWVRGTIAALRAELGVQLRAVIAAPVPGLSGVAAARAEVDRVL
MSMEG_6492|M.smegmatis_MC2_155 ----------------------ADRQATVAVGPGDVASHRESYQTAKGAL
Mvan_1323|M.vanbaalenii_PYR-1 -------------------RRGTPAAVAYSRPARGAQEVAGSYREARIAL
. . : . .
Mb1226c|M.bovis_AF2122/97 RTLSRLR--STQRVAFFAD--VKMVALISQNPDAASEFITSTLGDLES--
Rv1194c|M.tuberculosis_H37Rv RTLSRLR--STQRVAFFAD--VKMVALISQNPDAASEFITSTLGDLES--
MUL_0944|M.ulcerans_Agy99 RTLARLK--SDQRVAFFSD--VQIVALITQNTQAANEFITSTLGELES--
MLBr_01052|M.leprae_Br4923 RTLARLK--SHQQVAFFAD--VQLVSLITQNPEDAKEFITSTLGDFES--
MMAR_1127|M.marinum_M RMVAGLN--SRQRVALFAD--IQLIALIAQNPEAANDFIKNTLGDFES--
MAB_2657c|M.abscessus_ATCC_199 RLLARLG--SPLSVVRYED--VHLMDLLSADPASADQFVTDVLGEFQS--
Mflv_4621|M.gilvum_PYR-GCK VVAVAADGSSRHRIVAARDPGVALASMLMTDDATLKEWIHDVLGPLAQN-
TH_4306|M.thermoresistible__bu HVAHLCPR-IDSRVVDYRG--VDLLAVLLENPERAKEFAVRELGPLAAD-
MAV_1330|M.avium_104 DSAERHPLSFGQVTSLAEARTTVLLDEIVTLVGRDERLVDPRIVALHD--
MSMEG_6492|M.smegmatis_MC2_155 QVAIMSG--RTAAVVGLDDLGIAGLLLRINDPAALSTFARRTLAPILDYD
Mvan_1323|M.vanbaalenii_PYR-1 GIARRLG---HTGAVSYQDLRSFTVLADVADTDQSRALVADVLGPLRS--
: :
Mb1226c|M.bovis_AF2122/97 --ASPDLQTALLTFINEQCNASRAAKRLHTHRNTFLRRLESAQRLLPRPL
Rv1194c|M.tuberculosis_H37Rv --ASPDLQTALLTFINEQCNASRAAKRLHTHRNTFLRRLESAQRLLPRPL
MUL_0944|M.ulcerans_Agy99 --AAPELQATLLMFINEQCNASRAAKRLYTHRNTLLRRIEAAQRLLPRPL
MLBr_01052|M.leprae_Br4923 --ASPALQQTLLTFINEQCNASRAAKRLFTHRNTLLRRIESAEKLLPRPL
MMAR_1127|M.marinum_M --AGAELHKTVLTFVNEQCSIGRTTKVLYTHRNTLLRRLDRAQQLLPRPL
MAB_2657c|M.abscessus_ATCC_199 --ASPVLHQTVLTYVEEALNRTSTAERLYTHRNTIDRRLARVDELLPKPF
Mflv_4621|M.gilvum_PYR-GCK TASDQRLRDTLRVFLRAGSSFKAAANELQIHANTVKYRVNRALERRGRPI
TH_4306|M.thermoresistible__bu DERSRELRETIRHYL-ELCSPKAVAERMFLARGTVAYRLRQAEQALERSL
MAV_1330|M.avium_104 --REPVLAQTLRTYLDAFGDIAAAAHALRVHPNTVRYRVRRIEKLLSVSL
MSMEG_6492|M.smegmatis_MC2_155 HAHRTELLVTLRAYLECRQERSATATRLVIHPNTVAQRLRRIESLCSVTL
Mvan_1323|M.vanbaalenii_PYR-1 ---APDLLDFLIGYLAHGGNVNATARALNVHRNTMLTKLDRVSRATGLDI
* : :: . .: : .*. :: :
Mb1226c|M.bovis_AF2122/97 DHTSVHVAVALEALQWRGNKAHALSSPGRRSNSVPA
Rv1194c|M.tuberculosis_H37Rv DHTSVHVAVALEALQWRGNKAHALSSPGRRSNSVPA
MUL_0944|M.ulcerans_Agy99 AHTSVHVAVALEALQWRGDNIAKLPTPTSQDDEVPA
MLBr_01052|M.leprae_Br4923 DHTSVHIAVALEALQWRGDQTNTSGPRAGRNDGVPA
MMAR_1127|M.marinum_M DHSSVHVAVALEALQWRGN--------------PPA
MAB_2657c|M.abscessus_ATCC_199 ARNPIEVAAALTLLRVRAGR----------------
Mflv_4621|M.gilvum_PYR-GCK AAERLDVEVALLMCYWLGEVALNPTQALGRS-----
TH_4306|M.thermoresistible__bu SERRLQLWTALVLADAIPPVPAER------------
MAV_1330|M.avium_104 ADPEVRLLFALALRAAER------------------
MSMEG_6492|M.smegmatis_MC2_155 TDPAVILQFSAALTVYDIAALD--------------
Mvan_1323|M.vanbaalenii_PYR-1 RLPDNQFTVWLAIRLDMLTEVHAAVDREAKFR----
.