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M. marinum M MMAR_0775 (-)

annotation: MmpL family transport protein
coordinates: 931210 - 934236
length: 1008

MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMAVPIVVFWVGLVAVLVMFVPS
LEEVGKQHTVSLSPSDAESMIAMKRVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDH
VQHVQDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTPAPPGVKAYVTGPAAL
IADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFA
VNLLVLMAIAAGTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRLPYF
QTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFKLFDPKRKMRTRGWRRVGTAIVRWPGPILAVSIAIALI
GLLALPGYRTNYDSKKYLPASTPTNVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVF
HLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAMQDSIDTLDRMYDIM
GKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKI
TEKLAALSRDMDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKAFDAA
RNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPASTEGISHVKPIMDEAKQAIKGTPLEG
AKIYLAGTASVYKDMRDGSRWDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVW
QDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGGVVTTAGLVFAATMA
SFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRA
LLLPRNGDSADGPEDTNTERLAVSSPHY
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0775--100% (1008)MmpL family transport protein
M. marinum MMMAR_0840mmpL20.067.89% (953) transmembrane transport protein, MmpL2
M. marinum MMMAR_0771mmpL5_20.066.88% (945) transmembrane transport protein MmpL5_2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0519mmpL20.069.63% (945) transmembrane transport protein MmpL2
M. gilvum PYR-GCKMflv_4418-0.066.31% (941) transport protein
M. tuberculosis H37RvRv0507mmpL20.069.74% (945) transmembrane transport protein MmpL2
M. leprae Br4923MLBr_02378-0.065.74% (937) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_2301-0.064.16% (932) putative membrane protein, mmpL
M. avium 104MAV_4696-0.065.36% (944) MmpL4 protein
M. smegmatis MC2 155MSMEG_3496-0.066.42% (944) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.061.18% (935) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.064.96% (939) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.066.70% (934) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3496|M.smegmatis_MC2_155      -MSNP----SHDAPTDAMGVSGPKHAR------------------PGGIA
TH_3260|M.thermoresistible__bu      MTANPGHVRTDEAPTDRLDIKVSTHG-------------------PSFIS
MUL_0757|M.ulcerans_Agy99           MTATT-----TDTPTDVVPP--AEHPP------------------RPFIP
MLBr_02378|M.leprae_Br4923          -------------MTVKCANDLDTHTK------------------PPFVA
MAB_2301|M.abscessus_ATCC_1997      -------------MSGSHAG--RSAAE------------------PTFLA
Mflv_4418|M.gilvum_PYR-GCK          ----------------------MADAG------------------RSGIG
Mvan_1936|M.vanbaalenii_PYR-1       ----------------------MADAG------------------RSGIG
Mb0519|M.bovis_AF2122/97            -------------MSERHAALTSLP---------------------PILP
Rv0507|M.tuberculosis_H37Rv         -------------MSERHAALTSLP---------------------PILP
MMAR_0775|M.marinum_M               -------MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMA
MAV_4696|M.avium_104                -------------MSEPVEAAPRVDQPLIP----------------PFLP
                                                                                    : 

MSMEG_3496|M.smegmatis_MC2_155      KWIRVLAVPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAM
TH_3260|M.thermoresistible__bu      TWIRRLSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAM
MUL_0757|M.ulcerans_Agy99           RMIRTFAVPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISM
MLBr_02378|M.leprae_Br4923          RMIHRFAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAM
MAB_2301|M.abscessus_ATCC_1997      KWIRRLSIPIVIGWLAIVFALNTFVPQLEQVGKEHTVSLSPQSAPSMQAM
Mflv_4418|M.gilvum_PYR-GCK          RIIRVLAVPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSM
Mvan_1936|M.vanbaalenii_PYR-1       RIIHLLAVPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSM
Mb0519|M.bovis_AF2122/97            RLIRRFAVVIVLLWLGFTAFVNLAVPQLEVVGKAHSVSMSPSDAASIQAI
Rv0507|M.tuberculosis_H37Rv         RLIRRFAVVIVLLWLGFTAFVNLAVPQLEVVGKAHSVSMSPSDAASIQAI
MMAR_0775|M.marinum_M               RLIHRMAVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAM
MAV_4696|M.avium_104                RMIHRLALPIVLVWLGIVFITNTVAPQLEVVAKTHSVSMSPTDAASFQSM
                                      *: ::: ::: *: :        *.*: *.: ::*.:*.  * *  ::

MSMEG_3496|M.smegmatis_MC2_155      KRVGEVFEEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEH
TH_3260|M.thermoresistible__bu      KRVGELFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVEN
MUL_0757|M.ulcerans_Agy99           KHIGKVFREGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQS
MLBr_02378|M.leprae_Br4923          QKMGQVFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQS
MAB_2301|M.abscessus_ATCC_1997      KHMGKMFKESDSDSVVMIVLEGQERLGPGSHKFYDEMVARLRADTKHVQH
Mflv_4418|M.gilvum_PYR-GCK          KRVGANFEEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQH
Mvan_1936|M.vanbaalenii_PYR-1       ERVGANFDEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQH
Mb0519|M.bovis_AF2122/97            KRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAH
Rv0507|M.tuberculosis_H37Rv         KRVGQVFGEFDSDNAVTIVLEGDQPLGGDAHRFYSDLMRKLSADTRHVAH
MMAR_0775|M.marinum_M               KRVGKVFNEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQH
MAV_4696|M.avium_104                MKVGATFKEFNSDNSAMILLEGDKPLGAEAHRYYDEIVRRVEQDKKHVQH
                                     ::*  * * .::.   ::***:. **  :: :*. :: .:  *  :*  

MSMEG_3496|M.smegmatis_MC2_155      VQDFWGDPLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVES
TH_3260|M.thermoresistible__bu      VQDLWSDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIAT
MUL_0757|M.ulcerans_Agy99           VQDFWGDPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDS
MLBr_02378|M.leprae_Br4923          VQDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQ
MAB_2301|M.abscessus_ATCC_1997      VQDFWGDPLTEAGAQSTDGKATYVQVNLAGNMGETLSNESTEAARNIVKQ
Mflv_4418|M.gilvum_PYR-GCK          IADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDR
Mvan_1936|M.vanbaalenii_PYR-1       VADFWGDPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQ
Mb0519|M.bovis_AF2122/97            IQHFWGDPLTAAGSQSADDRAAYVVVYLVGNN-ETEAYDSVHAVRHMVDT
Rv0507|M.tuberculosis_H37Rv         IQDFWGDPLTAAGSQSADDRAAYVVVYLVGNN-ETEAYDSVHAVRHMVDT
MMAR_0775|M.marinum_M               VQDFWGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVND
MAV_4696|M.avium_104                VQDFWSDPLTAAGSQSHDQKAAYVQVYLAGNMGGGLANESALAVRKIVDS
                                    : .:*.**** .* ** *  ::**     **     : ::  :.: ::  

MSMEG_3496|M.smegmatis_MC2_155      VP---------APPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVII
TH_3260|M.thermoresistible__bu      VSEE------MAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVIT
MUL_0757|M.ulcerans_Agy99           LQ---------APPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVII
MLBr_02378|M.leprae_Br4923          TPA---------PPGITAWVTGASALIADMHHSGDKSMIRITATSVIVIL
MAB_2301|M.abscessus_ATCC_1997      LEADWTKDGNKLPDGLTVYVTGPGALQTDMNHAGDGSLQLITGLTFLVIV
Mflv_4418|M.gilvum_PYR-GCK          TP---------APPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIA
Mvan_1936|M.vanbaalenii_PYR-1       TP---------APPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIA
Mb0519|M.bovis_AF2122/97            TP---------PPHGVKAYVTGPAALNADQAEAGDKSIAKVTAITSMVIA
Rv0507|M.tuberculosis_H37Rv         TP---------PPHGVKAYVTGPAALNADQAEAGDKSIAKVTAITSMVIA
MMAR_0775|M.marinum_M               TP---------APPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIF
MAV_4696|M.avium_104                VP---------APPGIKAYVTGAGPLFADQSHAGEKGVAVVTLITFVVII
                                                * *: .:*** ..: :*   :.: .:  :   :  ** 

MSMEG_3496|M.smegmatis_MC2_155      TMLLLVYRSIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLL
TH_3260|M.thermoresistible__bu      TMLLFVYRSVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLL
MUL_0757|M.ulcerans_Agy99           VMLLLVYRSIITAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLL
MLBr_02378|M.leprae_Br4923          VTLLLVYRSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLL
MAB_2301|M.abscessus_ATCC_1997      VMLLFFYRSIFTVIMVFMLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLL
Mflv_4418|M.gilvum_PYR-GCK          VMLLIVFRSVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLL
Mvan_1936|M.vanbaalenii_PYR-1       VMLLLVFRSVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLL
Mb0519|M.bovis_AF2122/97            AMLLVIYRSVITAVLVLIMVGIDLGAIRGFIALLADHNIFSLSTFATNLL
Rv0507|M.tuberculosis_H37Rv         AMLLVIYRSVITAVLVLIMVGIDLGAIRGFIALLADHNIFSLSTFATNLL
MMAR_0775|M.marinum_M               VMLLSVYRSLITVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLL
MAV_4696|M.avium_104                VMLLVVYRSIITVAVMLGMVFIELAAARGVVATLGNYGVMGLSTFANNML
                                    . ** .:**. *    :  *     . ** :* *.   ::.**.** .:*

MSMEG_3496|M.smegmatis_MC2_155      TTLAIAAATDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMT
TH_3260|M.thermoresistible__bu      VTLAIAIAVDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLT
MUL_0757|M.ulcerans_Agy99           VVLAIAAATDYAIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLT
MLBr_02378|M.leprae_Br4923          TSLAIAAGTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLT
MAB_2301|M.abscessus_ATCC_1997      VMLSIAAGTDYAIFLIGRYQEARAMGADKEAAYYEMFHGTAHVILGSGMT
Mflv_4418|M.gilvum_PYR-GCK          TLMVIAAGTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLT
Mvan_1936|M.vanbaalenii_PYR-1       TLMVIAAGTDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLT
Mb0519|M.bovis_AF2122/97            VLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGTAHVILGSGLT
Rv0507|M.tuberculosis_H37Rv         VLMAIAASTDYAIFMLGRYHESRYAGEDRETAFYTMFHGTAHVILGSGLT
MMAR_0775|M.marinum_M               VLMAIAAGTDYAIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLT
MAV_4696|M.avium_104                VLMAIAAGTDYAIFVVGRYHEARGLGETREQAFYTMFHSTAHVVLGSGLT
                                    . : ** ..**.**  ***:*:*  .  :  ::: *: .* **:*.**:*

MSMEG_3496|M.smegmatis_MC2_155      IAGATLCLHFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGK
TH_3260|M.thermoresistible__bu      IAGATFCLSFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-
MUL_0757|M.ulcerans_Agy99           IAGATFCLSFTRLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGK
MLBr_02378|M.leprae_Br4923          ISGATFCLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-
MAB_2301|M.abscessus_ATCC_1997      IAGAMYCLSFTRMPYFQTLGVPCSVGLLVGVLVSLTLGPALITIGSRFG-
Mflv_4418|M.gilvum_PYR-GCK          IAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-
Mvan_1936|M.vanbaalenii_PYR-1       IAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-
Mb0519|M.bovis_AF2122/97            IAGAMYCLSFARLPYFETLGAPIAIGMLVAVLAALTLGPAVLTVGSFFK-
Rv0507|M.tuberculosis_H37Rv         IAGAMYCLSFARLPYFETLGAPIAIGMLVAVLAALTLGPAVLTVGSFFK-
MMAR_0775|M.marinum_M               IAGAMYCLSFTRLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-
MAV_4696|M.avium_104                IAGAMYCLSFCRLPYFQSLGVPCAVGMLVAVLAALTLAPAMLTVASFFK-
                                    *:**  ** * *:***:::* * ::*  : : .:**:..*:: : : *  

MSMEG_3496|M.smegmatis_MC2_155      TFEPKRAMRTRGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYN
TH_3260|M.thermoresistible__bu      LLEPKRAARVRFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYN
MUL_0757|M.ulcerans_Agy99           LLEPKRMARVRGWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYN
MLBr_02378|M.leprae_Br4923          LFEPKRLIKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYK
MAB_2301|M.abscessus_ATCC_1997      LFEPKRAMRIRSWRKIGTTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYD
Mflv_4418|M.gilvum_PYR-GCK          LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYD
Mvan_1936|M.vanbaalenii_PYR-1       LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYD
Mb0519|M.bovis_AF2122/97            LFDPKRRMNTRRWRRVGTAIVRWPGPVLAATCLVASIGLLALPSYRTTYD
Rv0507|M.tuberculosis_H37Rv         LFDPKRRMNTRRWRRVGTAIVRWPGPVLAATCLVASIGLLALPSYRTTYD
MMAR_0775|M.marinum_M               LFDPKRKMRTRGWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYD
MAV_4696|M.avium_104                LMDPKRTLQTRGWRRMGTAVVRWPAPVLAVTIAVALVGLLALPGYKTDYD
                                     ::***    * **::*. :**** *::  :  :: :** :**.*:* *.

MSMEG_3496|M.smegmatis_MC2_155      DRRYLPQDLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVD
TH_3260|M.thermoresistible__bu      DRNYLPASFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIE
MUL_0757|M.ulcerans_Agy99           DRNYLPADLPANEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVIN
MLBr_02378|M.leprae_Br4923          DRAYLPASIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILD
MAB_2301|M.abscessus_ATCC_1997      DKKYIPKDIPANAGFQAADRHFSQARMNPEMLLIESDHDMRNSADFLVID
Mflv_4418|M.gilvum_PYR-GCK          ARDYLPEDIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVID
Mvan_1936|M.vanbaalenii_PYR-1       SRDYLPEDVPANVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVID
Mb0519|M.bovis_AF2122/97            LRKFMPASMPSNVGDAAAGRHFSRARLNPEVLLIETDHDMRNPVDMLVLD
Rv0507|M.tuberculosis_H37Rv         LRKFMPASMPSNVGDAAAGRRFSRARLNPEVLLIETDHDMRNPVDMLVLD
MMAR_0775|M.marinum_M               SKKYLPASTPTNVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVID
MAV_4696|M.avium_104                NRHFLPADTPANVGYAAADRHFDQARLNPELLMIETDHDLRNPADFIVLD
                                     : ::* . *:* *  .* ::*  **::**:*::*:***:**. *:::::

MSMEG_3496|M.smegmatis_MC2_155      RIAKRVFQVPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQ
TH_3260|M.thermoresistible__bu      KIAKAVFQVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQ
MUL_0757|M.ulcerans_Agy99           KIAKAIFGVEGISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQ
MLBr_02378|M.leprae_Br4923          KLARGIFRVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQK
MAB_2301|M.abscessus_ATCC_1997      KIAKAVFRVPGIARVQAITRPQGTPIEHSSIPFLISMQSVGQRQNMKLMK
Mflv_4418|M.gilvum_PYR-GCK          KIAKSVFRVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQ
Mvan_1936|M.vanbaalenii_PYR-1       KIAKAIFRVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQ
Mb0519|M.bovis_AF2122/97            KVAKNIYHSPGIEQVKAITRPLGTTIKHTSIPFIISMQGVNSSEQMEFMK
Rv0507|M.tuberculosis_H37Rv         KVAKNIYHSPGIEQVKAITRPLGTTIKHTSIPFIISMQGVNSSEQMEFMK
MMAR_0775|M.marinum_M               RIAKGVFHLPGVARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMK
MAV_4696|M.avium_104                KVAKAVFHIPGIGRVQTITRPLGTPLDHSTLGFQMGAQAAGRLQTQHYQE
                                    ::*: ::   *: :*: :*** *..:.*::: * :.   .      .  :

MSMEG_3496|M.smegmatis_MC2_155      DRMADMLVMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKE
TH_3260|M.thermoresistible__bu      DRMADMLVQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAE
MUL_0757|M.ulcerans_Agy99           DLTTSMLQQVNDIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEE
MLBr_02378|M.leprae_Br4923          DRMNDLLRQAENMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSK
MAB_2301|M.abscessus_ATCC_1997      DRMADMKVQADKMGENVVIMKRTLANMTTMAGITHSLVGDMHTLQGTIHE
Mflv_4418|M.gilvum_PYR-GCK          DRMADMLVQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIE
Mvan_1936|M.vanbaalenii_PYR-1       DRMADMLVQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVE
Mb0519|M.bovis_AF2122/97            DRIYDILVQVAAMNTSIETMHRMYALMGEVIDNTVDMDHLTHDMSDITAT
Rv0507|M.tuberculosis_H37Rv         DRIDDILVQVAAMNTSIETMHRMYALMGEVIDNTVDMDHLTHDMSDITAT
MMAR_0775|M.marinum_M               QRMADMLIQAAAMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDE
MAV_4696|M.avium_104                EQANNLLKQADELRKTMATLHEQMQVTQDLSNTTHETTRLTKETVQITER
                                    :   .:   .  :   :  : .       :   *                

MSMEG_3496|M.smegmatis_MC2_155      LRDHIADFDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDD
TH_3260|M.thermoresistible__bu      MRDSISEFDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDD
MUL_0757|M.ulcerans_Agy99           LRNHIADFDDFFRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTED
MLBr_02378|M.leprae_Br4923          LRDEIANFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDER
MAB_2301|M.abscessus_ATCC_1997      MRDSISNFDDWFRPIRNYLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTET
Mflv_4418|M.gilvum_PYR-GCK          VRDNLADFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDD
Mvan_1936|M.vanbaalenii_PYR-1       VRDYLANLDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDD
Mb0519|M.bovis_AF2122/97            LRDHLADFEDFFRPIRSYFYWEKHCFDVPLCWSIRSIFDMFDSVDQLSEK
Rv0507|M.tuberculosis_H37Rv         LRDHLADFEDFFRPIRSYFYWEKHCFDVPLCWSIRSIFDMFDSVDQLSEK
MMAR_0775|M.marinum_M               LRDHIADFDDFWRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEK
MAV_4696|M.avium_104                LRDDIANFDDFLRPIRSYFYWEKHCYDIPVCWALRSVFNALDGIDQVAEN
                                    :*: :::::*: **:*.*:*** ** .:*:* ::**:*: :* :: : : 

MSMEG_3496|M.smegmatis_MC2_155      IQRLMPDMDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQM
TH_3260|M.thermoresistible__bu      IQNMLPHMHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQM
MUL_0757|M.ulcerans_Agy99           INNLLPLMERLDTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQM
MLBr_02378|M.leprae_Br4923          LNSIVGDIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQM
MAB_2301|M.abscessus_ATCC_1997      MDGMVVNMERMDTLMPKMVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQM
Mflv_4418|M.gilvum_PYR-GCK          ISELIPDLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQN
Mvan_1936|M.vanbaalenii_PYR-1       IQELIPDLERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQM
Mb0519|M.bovis_AF2122/97            LEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHGTLGAFYKQQ
Rv0507|M.tuberculosis_H37Rv         LEYLVKDMDILITLLPQMRAQMPPMISAMTTMRDMMLIWHGTLGAFYKQQ
MMAR_0775|M.marinum_M               LAALSRDMDRLDILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQM
MAV_4696|M.avium_104                IVNLSANLDKLDRIQPKLVALIPPQIESQQRNLDTIMSNYAITQGLNDQA
                                    :  :   :. :  : *::   :.  :         ::       .  .* 

MSMEG_3496|M.smegmatis_MC2_155      EAAMENQTAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAV
TH_3260|M.thermoresistible__bu      AEMQENANAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAV
MUL_0757|M.ulcerans_Agy99           AAMQEDSSAMGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAV
MLBr_02378|M.leprae_Br4923          NELSDNANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAA
MAB_2301|M.abscessus_ATCC_1997      DEMSQNSTAMGKAFDAAKNDDSFYLPPEIFDNADFKRGMKSFLSPDGKAV
Mflv_4418|M.gilvum_PYR-GCK          AAMSEDADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSV
Mvan_1936|M.vanbaalenii_PYR-1       ASQSEDADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSV
Mb0519|M.bovis_AF2122/97            ERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAA
Rv0507|M.tuberculosis_H37Rv         ERNNKDPGAMGRVFDAAQIDDSFYLPQSAFENPDFKRGLKMFLSPDGKAA
MMAR_0775|M.marinum_M               DEMSKNSTAMGKAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAV
MAV_4696|M.avium_104                KAQADNATAQGDAFDKAKNDDTFYLPPEAFKSPDFARGLKNFISPDGRAV
                                        .:  : * .** :  **:**:* . *.. ** *.:: *:*.**::.

MSMEG_3496|M.smegmatis_MC2_155      RFIISHEGDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFK
TH_3260|M.thermoresistible__bu      RFIISHQGDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFK
MUL_0757|M.ulcerans_Agy99           RFIISHEGDPMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFK
MLBr_02378|M.leprae_Br4923          RFIILHRGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFK
MAB_2301|M.abscessus_ATCC_1997      RMIISHRGDPATPEGLSHVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFK
Mflv_4418|M.gilvum_PYR-GCK          RFIISHEGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYK
Mvan_1936|M.vanbaalenii_PYR-1       RFIIAHEGDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYK
Mb0519|M.bovis_AF2122/97            RFVIALEGDPATPEGICRVEPIKREAREAIKGTPLQGAAIYLGGTAATFK
Rv0507|M.tuberculosis_H37Rv         RFVIALEGDPATPEGISRVEPIKREAREAIKGTPLQGAAIYLGGTAATFK
MMAR_0775|M.marinum_M               RFIISHEGDPASTEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYK
MAV_4696|M.avium_104                RLIISHEGDPASPEGIRHIEPIKQAVHEAIKGTPWEGAKVYLGGTAATYK
                                    *::*  .*** :  *:  :  *   . :*:**** :.: : *.**.: :*

MSMEG_3496|M.smegmatis_MC2_155      DLQEGANYDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASF
TH_3260|M.thermoresistible__bu      DMSDGTKYDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASF
MUL_0757|M.ulcerans_Agy99           DLSDGNTFDLMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASF
MLBr_02378|M.leprae_Br4923          DIDEGANWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASF
MAB_2301|M.abscessus_ATCC_1997      DMSDGAKYDLMIAGISALCLIFLIMLLITRSFVASLVIVGTVALSLGASF
Mflv_4418|M.gilvum_PYR-GCK          DMSDGAFYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASF
Mvan_1936|M.vanbaalenii_PYR-1       DMRDGANYDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASF
Mb0519|M.bovis_AF2122/97            DIREGARYDLLIAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASF
Rv0507|M.tuberculosis_H37Rv         DIREGARYDLLIAGVAAISLILIIMMIITRSVVAAVVIVGTVVLSMGASF
MMAR_0775|M.marinum_M               DMRDGSRWDLLIAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASF
MAV_4696|M.avium_104                DMHDGSNIDLLIAGIAAATLIFIIMLVITRSVVAAFVIVGTVLLSLGASF
                                    *: :*   **:**.:::  **::**:::**:.**: ****** :*:.***

MSMEG_3496|M.smegmatis_MC2_155      GLSVLIWQHIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGL
TH_3260|M.thermoresistible__bu      GVSVLIWQYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGL
MUL_0757|M.ulcerans_Agy99           GLSVLIWQHVLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGI
MLBr_02378|M.leprae_Br4923          GLSVLLWQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGL
MAB_2301|M.abscessus_ATCC_1997      GLSVIIWQYILGIELHWLVMQMAIIVLLAVGSDYNLLLVSRLKEELHGGL
Mflv_4418|M.gilvum_PYR-GCK          GLSVLLWQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGL
Mvan_1936|M.vanbaalenii_PYR-1       GLSVLLWQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGL
Mb0519|M.bovis_AF2122/97            GLSVLVWQDILGIELYWMVLAMSVILLLAVGSDYNLLLISRLKEEIGAGL
Rv0507|M.tuberculosis_H37Rv         GLSVLVWQDILGIELYWMVLAMSVILLLAVGSDYNLLLISRLKEEIGAGL
MMAR_0775|M.marinum_M               GLSVLVWQDIFGVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGL
MAV_4696|M.avium_104                GLSVLLWQYLLGLKLHWMVLAMAVILLLAVGSDYNLLLISRFKEEIHAGL
                                    *:**::** :.*: ::::*: *::*:*****:*****:::*:::*: .*:

MSMEG_3496|M.smegmatis_MC2_155      NTGIIRSMGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLF
TH_3260|M.thermoresistible__bu      NTGMIRAMGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLF
MUL_0757|M.ulcerans_Agy99           NTGIIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLF
MLBr_02378|M.leprae_Br4923          KTGIIRSMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLF
MAB_2301|M.abscessus_ATCC_1997      KTGIIRSMGGTGSVVTSAGLVFAFTMAVMVVSDLRIIGQVGTTIALGLLF
Mflv_4418|M.gilvum_PYR-GCK          KTGIIRAMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLF
Mvan_1936|M.vanbaalenii_PYR-1       KTGIIRSMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLF
Mb0519|M.bovis_AF2122/97            NTGIIRAMAGTGGVVTAAGMVFAVTMSLFVFSDLRIIGQIGTTIGLGLLF
Rv0507|M.tuberculosis_H37Rv         NTGIIRAMAGTGGVVTAAGMVFAVTMSLFVFSDLRIIGQIGTTIGLGLLF
MMAR_0775|M.marinum_M               KTGIIRAMAGTGGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLF
MAV_4696|M.avium_104                KTGTIRAMAGSGSVVTSAGLVFAATMATFMFSPLLVMAQVGTTIALGLLF
                                    :** **:*.*:* *** **:**. **  : .* * ::.*:****.:****

MSMEG_3496|M.smegmatis_MC2_155      DTLVIRSFMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNR
TH_3260|M.thermoresistible__bu      DTFVVRSFMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDR
MUL_0757|M.ulcerans_Agy99           DTLIVRSFMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV
MLBr_02378|M.leprae_Br4923          DTLIVRSFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPDRSLVYS
MAB_2301|M.abscessus_ATCC_1997      DTLIVRSFMTPAVATLLGRWFWWPLNVRTRPLPPPRTTVAADPTPPPVPV
Mflv_4418|M.gilvum_PYR-GCK          DTLIVRSFMTPAVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR--
Mvan_1936|M.vanbaalenii_PYR-1       DTLIVRSFMTPAVAALLGRWFWWPQKVRSHASQRRLAALNH---------
Mb0519|M.bovis_AF2122/97            DTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAPRRLVRALLL
Rv0507|M.tuberculosis_H37Rv         DTLVVRSFMTPSIAALLGRWFWWPLRVRPRPASQMLRPFAPRRLVRALLL
MMAR_0775|M.marinum_M               DTLIVRSFMTPSIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLL
MAV_4696|M.avium_104                DTLIVRSFMTPSLATLLGRWFWWPQHVRPRPASTMLRPYGPRRAVRELIL
                                    **:::**** *::*:*:*:*****   *  .                   

MSMEG_3496|M.smegmatis_MC2_155      V------------------------
TH_3260|M.thermoresistible__bu      VSV----------------------
MUL_0757|M.ulcerans_Agy99           -------------------------
MLBr_02378|M.leprae_Br4923          D------------------------
MAB_2301|M.abscessus_ATCC_1997      GPGHGDDPITTEFPRPSV-------
Mflv_4418|M.gilvum_PYR-GCK          -------------------------
Mvan_1936|M.vanbaalenii_PYR-1       -------------------------
Mb0519|M.bovis_AF2122/97            P----SGQHPSATGAHE--------
Rv0507|M.tuberculosis_H37Rv         P----SGQHPSATGAHE--------
MMAR_0775|M.marinum_M               PRNGDSADGPEDTNTERLAVSSPHY
MAV_4696|M.avium_104                AD---VDEHPPGGVVQPR-------