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TVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVFIPSLEVVGQERSVSLSPKDAPSYEAM KRIGAAFNEGNSDSQAMIVLEGKDALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGK AAYVQLNLAGNQGEPLANESVEAVRKIVKETPAPPGVTTYVTGAAALVSDMHSSGDKSMIKITVTTVAVI FIMLLLVYRSVITVVVLLLTVGVELTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRY QEARQAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPCAVGMLVAVMVALTLGP AVLTVGSRFGLFDPKRLIKVRGWRRVGTVVVRWPLPVLAATLAVALVGLLALPGYRTNYNDRDYLPNFIP ANQGFTAAERHFSQARMKPDILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPDGTAMDHTS IPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRRMYGLMTQLANNTHKMVGDTIEMQQITKE LRDHIANFDDFFRPIRSYFYWEKHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIE TFPPMIETMESMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDSFYLPPEVFKNEDFKRAMK SFLSPDGHAARFIILHRGDPQSAQGIASIDQIRTAAEESLKGTPLEDAKIYVAGTASVFKDISEGADWDL LIAGISSLCLIFIIMLILTRAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAMSVIVLLAV GSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVFAFTMASMAVSDLRVIGQVGTTIGLGLLF DTLIVRAFMTPSIAALLGRWFWWPMRVRTRPARTPSSPTADPEPDRALAMSGER*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0771 | mmpL5_2 | - | 100% (965) | transmembrane transport protein MmpL5_2 |
M. marinum M | MMAR_0255 | mmpL5_4 | 0.0 | 79.05% (945) | transmembrane transport protein, MmpL5_4 |
M. marinum M | MMAR_4429 | - | 0.0 | 75.77% (937) | transmembrane transport protein, MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 81.66% (965) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 64.66% (931) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 81.76% (965) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 80.67% (962) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 63.10% (954) | putative membrane protein, mmpL |
M. avium 104 | MAV_2510 | - | 0.0 | 65.41% (928) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 63.89% (947) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 62.55% (940) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 64.48% (946) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 64.98% (931) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 MSTKFANDSNTN------ARPEKPFIARMIHAFAVPIILGWLAVCVVVTV Rv0450c|M.tuberculosis_H37Rv MSTKFANDSNTN------ARPEKPFIARMIHAFAVPIILGWLAVCVVVTV MMAR_0771|M.marinum_M MTVKYANDPDTR------THTEKPFLARMIHAFAVPIILAWVAVCVALSV MLBr_02378|M.leprae_Br4923 MTVKCANDLDTH------TKP--PFVARMIHRFAVPIILVWLAIAVTVSV Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAA--HGPHRSFIPRMIRLFAVPIILGWIALIVVVNV Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAA--RQPHRPFIPRMIRLFAVPIILGWIALIVILNV MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPA--EHPPRPFIPRMIRTFAVPLILGWVLLIAVLNS MAV_2510|M.avium_104 MSTTFDDTRTDAIPVV--KEPVREKIPRFIRAFAVPIIIGWIALIAVLNV MSMEG_3496|M.smegmatis_MC2_155 MSNPSHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPIILVWVAIIAVLNT MAB_2301|M.abscessus_ATCC_1997 MSGSHAGR----------SAAEPTFLAKWIRRLSIPIVIGWLAIVFALNT TH_3056|M.thermoresistible__bu MSVLDRVG----------VEPRRPRVASFIRRYSVLIILGWVALTVLATV *: . :. *: :: ::: *: : . Mb0458c|M.bovis_AF2122/97 FVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN Rv0450c|M.tuberculosis_H37Rv FVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN MMAR_0771|M.marinum_M FIPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGK MLBr_02378|M.leprae_Br4923 FIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD Mflv_3435|M.gilvum_PYR-GCK TVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIVFEGD Mvan_3189|M.vanbaalenii_PYR-1 TVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIVFEGD MUL_0757|M.ulcerans_Agy99 VVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ MAV_2510|M.avium_104 VVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIVLEGQ MSMEG_3496|M.smegmatis_MC2_155 VVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVMIVLEGE MAB_2301|M.abscessus_ATCC_1997 FVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMIVLEGQ TH_3056|M.thermoresistible__bu AVPPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ :* *: * . :::.: * * : : ::* * * .*:* ::::**. Mb0458c|M.bovis_AF2122/97 QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY Rv0450c|M.tuberculosis_H37Rv QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY MMAR_0771|M.marinum_M DALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAY MLBr_02378|M.leprae_Br4923 KPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAY Mflv_3435|M.gilvum_PYR-GCK QPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDGKAAY Mvan_3189|M.vanbaalenii_PYR-1 QPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDGKAAY MUL_0757|M.ulcerans_Agy99 EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY MAV_2510|M.avium_104 QPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSNDGKASY MSMEG_3496|M.smegmatis_MC2_155 QPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQSPDGLASY MAB_2301|M.abscessus_ATCC_1997 ERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQSTDGKATY TH_3056|M.thermoresistible__bu EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF . ** :* :** :: :*. . :*: ::*:*.**** . ** ** *:: Mb0458c|M.bovis_AF2122/97 VQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGIKAYVTGP Rv0450c|M.tuberculosis_H37Rv VQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGIKAYVTGP MMAR_0771|M.marinum_M VQLNLAGNQGEPLANESVEAVRKIVKETPA---------PPGVTTYVTGA MLBr_02378|M.leprae_Br4923 VQLSLAGNQGELLAQESIDAVRKIVVQTPA---------PPGITAWVTGA Mflv_3435|M.gilvum_PYR-GCK VQVKLSGNQGEALANESVKAVQQTVSSLEP---------PPGVRAFVTGP Mvan_3189|M.vanbaalenii_PYR-1 VQVKLAGNQGESLANESVQAAQEIVRSLEP---------PPGVRAFVTGP MUL_0757|M.ulcerans_Agy99 VQVKLAGNQGESLANESVEAVKTIVDSLQA---------PPGVKVYVTGS MAV_2510|M.avium_104 VQVYLAGNQGEALANESVESVQNIVKSVQA---------PNGVKAYVTGP MSMEG_3496|M.smegmatis_MC2_155 VQVYTRGNQGEALANESVEAVQDIVESVPA---------PPGVKAYVTGP MAB_2301|M.abscessus_ATCC_1997 VQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLTVYVTGP TH_3056|M.thermoresistible__bu VQVNLVGRFGQAKVNEAVRAVQEIVERTPA---------PEGVETFVTGP **: *. * :*: :.: * . * *: .:***. Mb0458c|M.bovis_AF2122/97 SALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVE Rv0450c|M.tuberculosis_H37Rv SALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVE MMAR_0771|M.marinum_M AALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVE MLBr_02378|M.leprae_Br4923 SALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIE Mflv_3435|M.gilvum_PYR-GCK AALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMS Mvan_3189|M.vanbaalenii_PYR-1 AALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLS MUL_0757|M.ulcerans_Agy99 AALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLG MAV_2510|M.avium_104 AALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLE MSMEG_3496|M.smegmatis_MC2_155 AALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTLVMVVLS MAB_2301|M.abscessus_ATCC_1997 GALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMVFMLVGIQ TH_3056|M.thermoresistible__bu AALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVE .** :* :. :: * :. **. **:.:**..*. : : * : Mb0458c|M.bovis_AF2122/97 LTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR Rv0450c|M.tuberculosis_H37Rv LTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR MMAR_0771|M.marinum_M LTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEAR MLBr_02378|M.leprae_Br4923 SAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEAR Mflv_3435|M.gilvum_PYR-GCK LATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEAR Mvan_3189|M.vanbaalenii_PYR-1 LATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEAR MUL_0757|M.ulcerans_Agy99 LLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR MAV_2510|M.avium_104 LSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEAR MSMEG_3496|M.smegmatis_MC2_155 LSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLIGRYQEAR MAB_2301|M.abscessus_ATCC_1997 LSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLIGRYQEAR TH_3056|M.thermoresistible__bu LQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAR .:** :* ** :**: :...**. :.***.***.**: ******* Mb0458c|M.bovis_AF2122/97 QAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPC Rv0450c|M.tuberculosis_H37Rv QAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPC MMAR_0771|M.marinum_M QAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPC MLBr_02378|M.leprae_Br4923 QANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPC Mflv_3435|M.gilvum_PYR-GCK TAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPL Mvan_3189|M.vanbaalenii_PYR-1 TNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPL MUL_0757|M.ulcerans_Agy99 GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL MAV_2510|M.avium_104 AVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTLGIPL MSMEG_3496|M.smegmatis_MC2_155 SVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPL MAB_2301|M.abscessus_ATCC_1997 AMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQTLGVPC TH_3056|M.thermoresistible__bu EAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPG . .:: ::: : .. :*: .**:**:** ** *:.:*:*:.:*:* Mb0458c|M.bovis_AF2122/97 AVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRW Rv0450c|M.tuberculosis_H37Rv AVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRW MMAR_0771|M.marinum_M AVGMLVAVMVALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRW MLBr_02378|M.leprae_Br4923 AVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRW Mflv_3435|M.gilvum_PYR-GCK AIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRW Mvan_3189|M.vanbaalenii_PYR-1 AIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRW MUL_0757|M.ulcerans_Agy99 AIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRW MAV_2510|M.avium_104 AIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTVVVRW MSMEG_3496|M.smegmatis_MC2_155 AIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKLGAAVVRW MAB_2301|M.abscessus_ATCC_1997 SVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKIGTTIVRW TH_3056|M.thermoresistible__bu AVGLLVAVAVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRW ::*: : * ..: : * : : :** ::*:* : **::*:.:*** Mb0458c|M.bovis_AF2122/97 PLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFS Rv0450c|M.tuberculosis_H37Rv PLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFS MMAR_0771|M.marinum_M PLPVLAATLAVALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFS MLBr_02378|M.leprae_Br4923 PLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFP Mflv_3435|M.gilvum_PYR-GCK PGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFD Mvan_3189|M.vanbaalenii_PYR-1 PGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFD MUL_0757|M.ulcerans_Agy99 PGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFS MAV_2510|M.avium_104 PGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAADRHFS MSMEG_3496|M.smegmatis_MC2_155 PAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYAAADRHFS MAB_2301|M.abscessus_ATCC_1997 PGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQAADRHFS TH_3056|M.thermoresistible__bu PVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFP * *:* : .::::** :****...*.*: ::* :**. *: .* .** Mb0458c|M.bovis_AF2122/97 QARMK-PEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPE Rv0450c|M.tuberculosis_H37Rv QARMK-PEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPE MMAR_0771|M.marinum_M QARMK-PDILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPD MLBr_02378|M.leprae_Br4923 QARMK-PEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPD Mflv_3435|M.gilvum_PYR-GCK QARMN-PELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPD Mvan_3189|M.vanbaalenii_PYR-1 QARMN-PELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPD MUL_0757|M.ulcerans_Agy99 QARMN-PEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPD MAV_2510|M.avium_104 QARMN-PEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAITRPQ MSMEG_3496|M.smegmatis_MC2_155 QARMN-PELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQAITRPQ MAB_2301|M.abscessus_ATCC_1997 QARMN-PEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQAITRPQ TH_3056|M.thermoresistible__bu ASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPE : *. *:::::::*:*:**.:*:*:::::*: :* * *:..**::***: Mb0458c|M.bovis_AF2122/97 GTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTR Rv0450c|M.tuberculosis_H37Rv GTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTR MMAR_0771|M.marinum_M GTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRR MLBr_02378|M.leprae_Br4923 GTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRR Mflv_3435|M.gilvum_PYR-GCK GKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEK Mvan_3189|M.vanbaalenii_PYR-1 GKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEK MUL_0757|M.ulcerans_Agy99 GKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMER MAV_2510|M.avium_104 GTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDSMEK MSMEG_3496|M.smegmatis_MC2_155 GTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKSVDTMEE MAB_2301|M.abscessus_ATCC_1997 GTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENVVIMKR TH_3056|M.thermoresistible__bu GRQIEHTTIPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRR * :.*::*** :**. . * : .: .: : .: : . Mb0458c|M.bovis_AF2122/97 MHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWE Rv0450c|M.tuberculosis_H37Rv MHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWE MMAR_0771|M.marinum_M MYGLMTQLANNTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWE MLBr_02378|M.leprae_Br4923 MHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWE Mflv_3435|M.gilvum_PYR-GCK MSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWE Mvan_3189|M.vanbaalenii_PYR-1 MSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWE MUL_0757|M.ulcerans_Agy99 MHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWE MAV_2510|M.avium_104 MQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYFYWE MSMEG_3496|M.smegmatis_MC2_155 MLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIRNYFYWE MAB_2301|M.abscessus_ATCC_1997 TLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIRNYLYWE TH_3056|M.thermoresistible__bu MQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWE : * :: : .:*: :::*:*: **:*.*::** Mb0458c|M.bovis_AF2122/97 KHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQI Rv0450c|M.tuberculosis_H37Rv KHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQI MMAR_0771|M.marinum_M KHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETF MLBr_02378|M.leprae_Br4923 RHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQF Mflv_3435|M.gilvum_PYR-GCK PHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALM Mvan_3189|M.vanbaalenii_PYR-1 PHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALM MUL_0757|M.ulcerans_Agy99 KHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMM MAV_2510|M.avium_104 KHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMVALM MSMEG_3496|M.smegmatis_MC2_155 PHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMPQMLTIM MAB_2301|M.abscessus_ATCC_1997 KHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMPKMVSDM TH_3056|M.thermoresistible__bu PHCYNIPICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQF ** .**:* ::**:**:** :: : : : :: : .:* ***:* : Mb0458c|M.bovis_AF2122/97 PPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDS Rv0450c|M.tuberculosis_H37Rv PPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDS MMAR_0771|M.marinum_M PPMIETMESMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDS MLBr_02378|M.leprae_Br4923 PPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDS Mflv_3435|M.gilvum_PYR-GCK PEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDS Mvan_3189|M.vanbaalenii_PYR-1 PEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDS MUL_0757|M.ulcerans_Agy99 PEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDS MAV_2510|M.avium_104 PSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKNDDS MSMEG_3496|M.smegmatis_MC2_155 PPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDASKNDDS MAB_2301|M.abscessus_ATCC_1997 SAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAAKNDDS TH_3056|M.thermoresistible__bu PQMIETMESSRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDS . * *: : :*: : * :* .: :**:*** : **** Mb0458c|M.bovis_AF2122/97 FYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAI Rv0450c|M.tuberculosis_H37Rv FYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAI MMAR_0771|M.marinum_M FYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQI MLBr_02378|M.leprae_Br4923 FYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAI Mflv_3435|M.gilvum_PYR-GCK FYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKI Mvan_3189|M.vanbaalenii_PYR-1 FYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKI MUL_0757|M.ulcerans_Agy99 FYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKI MAV_2510|M.avium_104 FYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHIGAI MSMEG_3496|M.smegmatis_MC2_155 FYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIKHIDAI MAB_2301|M.abscessus_ATCC_1997 FYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGLSHVEPI TH_3056|M.thermoresistible__bu FYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPI ****** :.* :*:: :: *:*.**:*.*::: : *** : *: : * Mb0458c|M.bovis_AF2122/97 RTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIF Rv0450c|M.tuberculosis_H37Rv RTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIF MMAR_0771|M.marinum_M RTAAEESLKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIF MLBr_02378|M.leprae_Br4923 RTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIF Mflv_3435|M.gilvum_PYR-GCK KTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIF Mvan_3189|M.vanbaalenii_PYR-1 KTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIF MUL_0757|M.ulcerans_Agy99 KTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIF MAV_2510|M.avium_104 KKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIF MSMEG_3496|M.smegmatis_MC2_155 KQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIAALCLIF MAB_2301|M.abscessus_ATCC_1997 KQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGISALCLIF TH_3056|M.thermoresistible__bu YIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIF ** *::******.: * :.*:.: :*: :* :**:**.*::: *** Mb0458c|M.bovis_AF2122/97 IIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAM Rv0450c|M.tuberculosis_H37Rv IIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAM MMAR_0771|M.marinum_M IIMLILTRAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAM MLBr_02378|M.leprae_Br4923 IIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAM Mflv_3435|M.gilvum_PYR-GCK IIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAM Mvan_3189|M.vanbaalenii_PYR-1 IIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAM MUL_0757|M.ulcerans_Agy99 IIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAM MAV_2510|M.avium_104 IIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVLAM MSMEG_3496|M.smegmatis_MC2_155 IIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAM MAB_2301|M.abscessus_ATCC_1997 LIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHWLVMQM TH_3056|M.thermoresistible__bu MIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAM :**:::**..:*: ****** :**.****:**::**::: **::*: * Mb0458c|M.bovis_AF2122/97 SVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVF Rv0450c|M.tuberculosis_H37Rv SVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVF MMAR_0771|M.marinum_M SVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVF MLBr_02378|M.leprae_Br4923 SVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVF Mflv_3435|M.gilvum_PYR-GCK AVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVF Mvan_3189|M.vanbaalenii_PYR-1 AVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVF MUL_0757|M.ulcerans_Agy99 AVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVF MAV_2510|M.avium_104 SVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVF MSMEG_3496|M.smegmatis_MC2_155 AVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVF MAB_2301|M.abscessus_ATCC_1997 AIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTSAGLVF TH_3056|M.thermoresistible__bu SVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVF ::*:*****:****:**:*:*:*: .*: *****:***:* *** ***** Mb0458c|M.bovis_AF2122/97 AVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW Rv0450c|M.tuberculosis_H37Rv AVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW MMAR_0771|M.marinum_M AFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFW MLBr_02378|M.leprae_Br4923 AFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFW Mflv_3435|M.gilvum_PYR-GCK ALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFW Mvan_3189|M.vanbaalenii_PYR-1 ALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFW MUL_0757|M.ulcerans_Agy99 AFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFW MAV_2510|M.avium_104 AFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGKWFW MSMEG_3496|M.smegmatis_MC2_155 AFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAALMGKWFW MAB_2301|M.abscessus_ATCC_1997 AFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATLLGRWFW TH_3056|M.thermoresistible__bu AATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFW * ** : **:* ::.******.:******:::*::* *::*:::* *** Mb0458c|M.bovis_AF2122/97 WPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG------------ Rv0450c|M.tuberculosis_H37Rv WPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG------------ MMAR_0771|M.marinum_M WPMRVRTRPARTPSSPTADPEPDRALAMSGER-------------- MLBr_02378|M.leprae_Br4923 WPQQGRTRPLLTVAAPVG-LPPDRSLVYSD---------------- Mflv_3435|M.gilvum_PYR-GCK WPQRVRTRPVPAPWPRSGGLQSDPSEGVRA---------------- Mvan_3189|M.vanbaalenii_PYR-1 WPQRVRTRPVPAPWPRPGGLQSDPSEGVKV---------------- MUL_0757|M.ulcerans_Agy99 WPQVVRQRPAPQPWPTPAPTPPPATTSV------------------ MAV_2510|M.avium_104 WPQRVRQRPVPSPWPKPAAQEREVLADA------------------ MSMEG_3496|M.smegmatis_MC2_155 WPQRVRQRPLPAPWPQPVQRDPEDALNRV----------------- MAB_2301|M.abscessus_ATCC_1997 WPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRPSV TH_3056|M.thermoresistible__bu WPQRVRTRPASAMLRPVGPRPLVRSLLLRD---------------- ** * **