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VPAGQPWNINIHYDALLAATVAPGTQTALDVGCGDGFLSARLADRVPDVTALDVDADVLRRAERRFADTS IRWVHGDVMTGELPHRGFDAVLANASLHHIEDTRGALIRLAELVLPAGTLAVVTFVRPSLRNGLWHLTAW LATGVANRVRRKWEHTAAIKWPPPVTFSQLRELVRELLPGARVRRLLYGRVLITWQAPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0244 | - | - | 100% (199) | methyltransferase/methylase |
| M. marinum M | MMAR_4799 | - | 3e-07 | 35.00% (100) | hypothetical protein MMAR_4799 |
| M. marinum M | MMAR_0694 | - | 3e-07 | 29.69% (128) | hypothetical protein MMAR_0694 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0092 | - | 9e-81 | 71.65% (194) | methyltransferase/methylase |
| M. gilvum PYR-GCK | Mflv_4692 | - | 3e-08 | 29.91% (107) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0089 | - | 9e-81 | 71.65% (194) | methyltransferase/methylase |
| M. leprae Br4923 | MLBr_00551 | - | 2e-05 | 25.00% (112) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_1294c | - | 3e-23 | 31.82% (198) | hypothetical protein MAB_1294c |
| M. avium 104 | MAV_0854 | - | 1e-08 | 38.74% (111) | methyltransferase-UbiE family protein |
| M. smegmatis MC2 155 | MSMEG_4708 | - | 5e-22 | 34.34% (198) | putative methyltransferase |
| M. thermoresistible (build 8) | TH_0144 | - | 3e-07 | 35.29% (119) | methyltransferase |
| M. ulcerans Agy99 | MUL_4869 | - | 1e-109 | 95.48% (199) | methyltransferase/methylase |
| M. vanbaalenii PYR-1 | Mvan_4082 | - | 8e-19 | 31.00% (200) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0244|M.marinum_M --------------MPAGQPWNIN--IHYDALLAATVAPGTQT-------
MUL_4869|M.ulcerans_Agy99 --------------MPAGQPWNIN--IHYDALLAATVAPGTQT-------
Mb0092|M.bovis_AF2122/97 ----------------MDQPWNAN--IHYDALLDAMVPLGTQC-------
Rv0089|M.tuberculosis_H37Rv ----------------MDQPWNAN--IHYDALLDAMVPLGTQC-------
MSMEG_4708|M.smegmatis_MC2_155 --------------MPSPAYWNHN--TAYHPWLRRIAAQHRGD-------
Mvan_4082|M.vanbaalenii_PYR-1 ----------------MQDYWNHN--TAYHPWLVGIAGEHRGD-------
MAB_1294c|M.abscessus_ATCC_199 --------------MPDHGRWNHN--IHYQREVLRRVPAHATD-------
MAV_0854|M.avium_104 --------------MNDQHRATYT--HGHHESVLRSHRRRTAEDSAGYLL
TH_0144|M.thermoresistible__bu ---------------------MWS--GRVNARLAEVAGELPPG-------
Mflv_4692|M.gilvum_PYR-GCK --------------MTSSTFWSAGRYDAVGDRIAPIAREVVDAADARRPL
MLBr_00551|M.leprae_Br4923 MNLYTPIHEDQSLAAIHRAMWALGDYALMAEEVMAPLGPILVTATGIRPG
:
MMAR_0244|M.marinum_M --------ALDVGCGDGFLSARLADRVP--DVTALDVDADVLRRAERRFA
MUL_4869|M.ulcerans_Agy99 --------ALDVGCGDGFLSARLVDRVP--DVTALDVDADVLRRAEHRFA
Mb0092|M.bovis_AF2122/97 --------VLDVGCGDGLLAARLARRIP--YVTAVDIDAPVLRRAQTRFA
Rv0089|M.tuberculosis_H37Rv --------VLDVGCGDGLLAARLARRIP--YVTAVDIDAPVLRRAQTRFA
MSMEG_4708|M.smegmatis_MC2_155 --------VLDVGCGDGLLAQRLAPVSR--SVTAIEPDPQTLQRAWVRLA
Mvan_4082|M.vanbaalenii_PYR-1 --------VLDIGCGDGLLAQRLLPVSR--SVTLIDPDPDSVARAQARLA
MAB_1294c|M.abscessus_ATCC_199 --------VLDVGCGIGMLTRELAPLAQ--RVVGIDPHEPSLRIARAETS
MAV_0854|M.avium_104 AHLTPGLSVLDVGCGPGTITADLAARVAPGQVTAVDQAADVLEVARAEAE
TH_0144|M.thermoresistible__bu -------RALDVGCGEGADAMWLAERGW--QVTAVDISQTALDRAAAEAA
Mflv_4692|M.gilvum_PYR-GCK R----DAAVVDLACGTGSAALDAAARGA--RVTGVDITPELIAIAAERDG
MLBr_00551|M.leprae_Br4923 ------MQVLDVAAGSGNISLPAAKTGA--TIVSTDLTPELLQRSQARAT
.:*:..* * : :. : : : .
MMAR_0244|M.marinum_M ---DTSIRWVHGDVMTGELPHRGFDAVLANASLHHIED-TRGALIRLAEL
MUL_4869|M.ulcerans_Agy99 ---DTSIWWVHGDVMTGELPHRGFDAVLASASLHHIEG-TRGALIRLAEL
Mb0092|M.bovis_AF2122/97 ---NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIED-TRTALSRLGGL
Rv0089|M.tuberculosis_H37Rv ---NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIED-TRTALSRLGGL
MSMEG_4708|M.smegmatis_MC2_155 H--LPNVTVAQNDFDTFDPGTHRFDVVTMVATLHHMD--LRAALSKAREL
Mvan_4082|M.vanbaalenii_PYR-1 G--HADVSISQQSFHDYRPGTALFDVITFVASLHHMA--LRESLRKARAL
MAB_1294c|M.abscessus_ATCC_199 ---ASNVEYVRGSFLEHPFPAESFDLIAAVAALHHMD--IEQGLRRMSDL
MAV_0854|M.avium_104 QRNLSNVSFGTADVHRLDFADDTFDVVHAHQVLQHLSD-PVAALREMRRV
TH_0144|M.thermoresistible__bu SR-GLTIDFQRHELP-ATFPDGQFELVSAHFLHSEVELDRVRILRRAAEA
Mflv_4692|M.gilvum_PYR-GCK ---AAAVRWRTGDASDTGLPATSFDAAVSNMGIIFVEP--ARQVAEVVRL
MLBr_00551|M.leprae_Br4923 EL-GLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPD-HRRAASELVRV
: . *: .
MMAR_0244|M.marinum_M VLPAGT------------------LAVVTFVR-PSLRNGLWHLTAWLATG
MUL_4869|M.ulcerans_Agy99 VLPGGT------------------LAVVTFVR-PSPRNVLWHLTAWLATG
Mb0092|M.bovis_AF2122/97 VTPGGT------------------LAVVTFVT-PSLRNGLWHLTSWVACG
Rv0089|M.tuberculosis_H37Rv VTPGGT------------------LAVVTFVT-PSLRNGLWHLTSWVACG
MSMEG_4708|M.smegmatis_MC2_155 LTPTGE------------------IAVVGLSANKTLRDWAWSGLCLPAVR
Mvan_4082|M.vanbaalenii_PYR-1 LRPGGE------------------LAVVGLSANRSASDWIWSGLCLPAVR
MAB_1294c|M.abscessus_ATCC_199 LKPGGR------------------IVIVGFAANRSVTDLWYDGLGFWLHR
MAV_0854|M.avium_104 CRPGGI------------------VAVRDADYAGFIWYPELPALDLWRDL
TH_0144|M.thermoresistible__bu VVPGGL------------------LLIVDHGAPPPWAPDHVHEFEFPS--
Mflv_4692|M.gilvum_PYR-GCK LKPGGVFAFSSWVRSVSNPLFDPVLAVLGPPATSTFSPDQWGDEAVLTER
MLBr_00551|M.leprae_Br4923 CRPNGTIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAALWGREAYIRG
* * :
MMAR_0244|M.marinum_M VANRVRRKWEHTAA----IKWPPPVTFSQLR-------------------
MUL_4869|M.ulcerans_Agy99 VANRVRRKWDHTAA----IKWPPPVTFSQLR-------------------
Mb0092|M.bovis_AF2122/97 MANRVKGKWEHSAP----IKWPPPQTLHELR-------------------
Rv0089|M.tuberculosis_H37Rv MANRVKGKWEHSAP----IKWPPPQTLHELR-------------------
MSMEG_4708|M.smegmatis_MC2_155 LGSFCHRETRDIGV----PVAEPAENLDEIR-------------------
Mvan_4082|M.vanbaalenii_PYR-1 IGSRLHRETRDIGV----VVAQPRESLREIR-------------------
MAB_1294c|M.abscessus_ATCC_199 YYRLRYGWWEHPSP----VSCEGLDSHDEVR-------------------
MAV_0854|M.avium_104 YRRVARANRGEPDAGRRLLSWARQAGFDDITPTGSLWCYATPETRDWWGG
TH_0144|M.thermoresistible__bu -AQEVVESLQLPEG-----QWELLRAEPVKR-------------------
Mflv_4692|M.gilvum_PYR-GCK LGSQFDGVDVRRGD----HRWEFESMPAAMRFLTSE--------------
MLBr_00551|M.leprae_Br4923 LLDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYG--------------
MMAR_0244|M.marinum_M ---------ELVRELLPGARVRRLLYGRVLITWQAPG-------------
MUL_4869|M.ulcerans_Agy99 ---------ELVRELLPGARVRRLLYGRVLITWQAPG-------------
Mb0092|M.bovis_AF2122/97 ---------SHVRALLPGACIRRLLYGRVLVTWRAPV-------------
Rv0089|M.tuberculosis_H37Rv ---------SHVRALLPGACIRRLLYGRVLVTWRAPV-------------
MSMEG_4708|M.smegmatis_MC2_155 ---------RVAADVLPGAMIRRALYYRYLLRWQPAN-------------
Mvan_4082|M.vanbaalenii_PYR-1 ---------LVSDDVIPGAVVRRALYYRYLLRWRKPA-------------
MAB_1294c|M.abscessus_ATCC_199 ---------RIAQRVLPGARLQRLVLWRHLLTWEKS--------------
MAV_0854|M.avium_104 MWADRILHSTVARDLVSLGLAAREQLEEISAAWREWAAAPDGWIAIPHGE
TH_0144|M.thermoresistible__bu ------------DAVGPDGQQGTLIDNVIMLRRR----------------
Mflv_4692|M.gilvum_PYR-GCK -------SPMHVETFRRAETSQRARLAAEFEDALRPHLEPSGSVAFLSPY
MLBr_00551|M.leprae_Br4923 ------PTIEAYTNIGDNSVLAAELDAQLTELAQKYLTNSTMGWEYLLLT
.
MMAR_0244|M.marinum_M ---------
MUL_4869|M.ulcerans_Agy99 ---------
Mb0092|M.bovis_AF2122/97 ---------
Rv0089|M.tuberculosis_H37Rv ---------
MSMEG_4708|M.smegmatis_MC2_155 ---------
Mvan_4082|M.vanbaalenii_PYR-1 ---------
MAB_1294c|M.abscessus_ATCC_199 ---------
MAV_0854|M.avium_104 IICRA----
TH_0144|M.thermoresistible__bu ---------
Mflv_4692|M.gilvum_PYR-GCK VVVTATLRG
MLBr_00551|M.leprae_Br4923 AQKH-----