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MQDYWNHNTAYHPWLVGIAGEHRGDVLDIGCGDGLLAQRLLPVSRSVTLIDPDPDSVARAQARLAGHADV SISQQSFHDYRPGTALFDVITFVASLHHMALRESLRKARALLRPGGELAVVGLSANRSASDWIWSGLCLP AVRIGSRLHRETRDIGVVVAQPRESLREIRLVSDDVIPGAVVRRALYYRYLLRWRKPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4082 | - | - | 100% (198) | methyltransferase type 12 |
| M. vanbaalenii PYR-1 | Mvan_5517 | - | 3e-10 | 37.61% (109) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_4620 | - | 9e-07 | 33.96% (106) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0092 | - | 5e-20 | 33.50% (200) | methyltransferase/methylase |
| M. gilvum PYR-GCK | Mflv_4877 | - | 9e-06 | 26.09% (115) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0089 | - | 5e-20 | 33.50% (200) | methyltransferase/methylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1294c | - | 5e-28 | 35.68% (199) | hypothetical protein MAB_1294c |
| M. marinum M | MMAR_0244 | - | 9e-19 | 31.00% (200) | methyltransferase/methylase |
| M. avium 104 | MAV_0854 | - | 3e-06 | 33.33% (132) | methyltransferase-UbiE family protein |
| M. smegmatis MC2 155 | MSMEG_4708 | - | 6e-76 | 68.75% (192) | putative methyltransferase |
| M. thermoresistible (build 8) | TH_2193 | - | 1e-05 | 30.33% (122) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4869 | - | 1e-19 | 31.50% (200) | methyltransferase/methylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0092|M.bovis_AF2122/97 ---------------------------MDQPWNANIHYDALLDAMVPLGT
Rv0089|M.tuberculosis_H37Rv ---------------------------MDQPWNANIHYDALLDAMVPLGT
MMAR_0244|M.marinum_M -------------------------MPAGQPWNINIHYDALLAATVAPGT
MUL_4869|M.ulcerans_Agy99 -------------------------MPAGQPWNINIHYDALLAATVAPGT
Mvan_4082|M.vanbaalenii_PYR-1 ---------------------------MQDYWNHNTAYHPWLVGIAGEHR
MSMEG_4708|M.smegmatis_MC2_155 -------------------------MPSPAYWNHNTAYHPWLRRIAAQHR
MAB_1294c|M.abscessus_ATCC_199 -------------------------MPDHGRWNHNIHYQREVLRRVPAHA
MAV_0854|M.avium_104 -------------------------MNDQHRATYTHGHHESVLRSHRRRT
Mflv_4877|M.gilvum_PYR-GCK ------------------------MTAESDRRSLSFGAEAAAYERGRPSY
TH_2193|M.thermoresistible__bu MSAFSTAGSDADGPISVLPLTGERTVPGLERENYWFRRHEVVYQRLAHRC
. .
Mb0092|M.bovis_AF2122/97 QC----------------VLDVGCGDGLLAARLARRIP--YVTAVDIDAP
Rv0089|M.tuberculosis_H37Rv QC----------------VLDVGCGDGLLAARLARRIP--YVTAVDIDAP
MMAR_0244|M.marinum_M QT----------------ALDVGCGDGFLSARLADRVP--DVTALDVDAD
MUL_4869|M.ulcerans_Agy99 QT----------------ALDVGCGDGFLSARLVDRVP--DVTALDVDAD
Mvan_4082|M.vanbaalenii_PYR-1 GD----------------VLDIGCGDGLLAQRLLPVSR--SVTLIDPDPD
MSMEG_4708|M.smegmatis_MC2_155 GD----------------VLDVGCGDGLLAQRLAPVSR--SVTAIEPDPQ
MAB_1294c|M.abscessus_ATCC_199 TD----------------VLDVGCGIGMLTRELAPLAQ--RVVGIDPHEP
MAV_0854|M.avium_104 AEDSAGYLLAHL-TPGLSVLDVGCGPGTITADLAARVAPGQVTAVDQAAD
Mflv_4877|M.gilvum_PYR-GCK PPEAIDWLLADSGSRRLEVLDLGAGTGKLTTRLVERGL--DVVAVDPIPE
TH_2193|M.thermoresistible__bu AG--------------RVVLEAGCGEGYGADLLAEVAA--HVIGLDYDAA
.*: *.* * : * * ::
Mb0092|M.bovis_AF2122/97 VLRRAQTRFA---NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTR
Rv0089|M.tuberculosis_H37Rv VLRRAQTRFA---NAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTR
MMAR_0244|M.marinum_M VLRRAERRFA---DTSIRWVHGDVMTGELPHRGFDAVLANASLHHIEDTR
MUL_4869|M.ulcerans_Agy99 VLRRAEHRFA---DTSIWWVHGDVMTGELPHRGFDAVLASASLHHIEGTR
Mvan_4082|M.vanbaalenii_PYR-1 SVARAQARLAG--HADVSISQQSFHDYRPGTALFDVITFVASLHHMA-LR
MSMEG_4708|M.smegmatis_MC2_155 TLQRAWVRLAH--LPNVTVAQNDFDTFDPGTHRFDVVTMVATLHHMD-LR
MAB_1294c|M.abscessus_ATCC_199 SLRIARAETS---ASNVEYVRGSFLEHPFPAESFDLIAAVAALHHMD-IE
MAV_0854|M.avium_104 VLEVARAEAEQRNLSNVSFGTADVHRLDFADDTFDVVHAHQVLQHLSDPV
Mflv_4877|M.gilvum_PYR-GCK MLDLLRTSLP-----DTPALLGTAEEIPLPDDSVDAVLVAQAWHWFD-ET
TH_2193|M.thermoresistible__bu TVAHVRARYP-----RVDIRHGNLVDLPLADASVDVVVNFQVIEHLWDQE
: .* : . :
Mb0092|M.bovis_AF2122/97 TALSRLGGLVTPGGTLAVVTFVT-PSLRNG-----LWHLTSWVACGMANR
Rv0089|M.tuberculosis_H37Rv TALSRLGGLVTPGGTLAVVTFVT-PSLRNG-----LWHLTSWVACGMANR
MMAR_0244|M.marinum_M GALIRLAELVLPAGTLAVVTFVR-PSLRNG-----LWHLTAWLATGVANR
MUL_4869|M.ulcerans_Agy99 GALIRLAELVLPGGTLAVVTFVR-PSPRNV-----LWHLTAWLATGVANR
Mvan_4082|M.vanbaalenii_PYR-1 ESLRKARALLRPGGELAVVGLSANRSASDW-----IWSGLCLPAVRIGSR
MSMEG_4708|M.smegmatis_MC2_155 AALSKARELLTPTGEIAVVGLSANKTLRDW-----AWSGLCLPAVRLGSF
MAB_1294c|M.abscessus_ATCC_199 QGLRRMSDLLKPGGRIVIVGFAANRSVTDL-----WYDGLGFWLHRYYRL
MAV_0854|M.avium_104 AALREMRRVCRPGGIVAVRDADYAGFIWYP-----ELPALDLWRDLYRRV
Mflv_4877|M.gilvum_PYR-GCK RAVKEIARVLRPGGSLGLVWNNRDERLGWVKD---LGDIIGHEGDPWSQS
TH_2193|M.thermoresistible__bu KFIAECLRVLRPGGQLLVSTPNRITFTPGSDTPVNPFHTRELNAAELTEL
: . : * * : :
Mb0092|M.bovis_AF2122/97 VKGKWEHSAP----IKWPPPQTLHELR-----------------------
Rv0089|M.tuberculosis_H37Rv VKGKWEHSAP----IKWPPPQTLHELR-----------------------
MMAR_0244|M.marinum_M VRRKWEHTAA----IKWPPPVTFSQLR-----------------------
MUL_4869|M.ulcerans_Agy99 VRRKWDHTAA----IKWPPPVTFSQLR-----------------------
Mvan_4082|M.vanbaalenii_PYR-1 LHRETRDIGV----VVAQPRESLREIR-----------------------
MSMEG_4708|M.smegmatis_MC2_155 CHRETRDIGV----PVAEPAENLDEIR-----------------------
MAB_1294c|M.abscessus_ATCC_199 RYGWWEHPSP----VSCEGLDSHDEVR-----------------------
MAV_0854|M.avium_104 ARANRGEPDAGRRLLSWARQAGFDDITPTGSLWCYATPETRDWWGGMWAD
Mflv_4877|M.gilvum_PYR-GCK VELPAPFTGVERHHVEWTSYLTPQALIDLVASR-----------------
TH_2193|M.thermoresistible__bu LTDGGFGLSAMYGVFHGPRLAELDARHGGSIIDAQISR------------
Mb0092|M.bovis_AF2122/97 -----SHVRALLPGACIRRLLYGR----VLVTWRAPV-------------
Rv0089|M.tuberculosis_H37Rv -----SHVRALLPGACIRRLLYGR----VLVTWRAPV-------------
MMAR_0244|M.marinum_M -----ELVRELLPGARVRRLLYGR----VLITWQAPG-------------
MUL_4869|M.ulcerans_Agy99 -----ELVRELLPGARVRRLLYGR----VLITWQAPG-------------
Mvan_4082|M.vanbaalenii_PYR-1 -----LVSDDVIPGAVVRRALYYR----YLLRWRKPA-------------
MSMEG_4708|M.smegmatis_MC2_155 -----RVAADVLPGAMIRRALYYR----YLLRWQPAN-------------
MAB_1294c|M.abscessus_ATCC_199 -----RIAQRVLPGARLQRLVLWR----HLLTWEKS--------------
MAV_0854|M.avium_104 RILHSTVARDLVSLGLAAREQLEE----ISAAWREWAAAPDGWIAIPHGE
Mflv_4877|M.gilvum_PYR-GCK -----SYCITSPERVRARTLDRVR----ELLTTHPALANSSG-LALPYVT
TH_2193|M.thermoresistible__bu -----ALADEPWPAELLADVASVRTEDFDLIRCDEDDRDRDGHNIDDSLD
.
Mb0092|M.bovis_AF2122/97 --------
Rv0089|M.tuberculosis_H37Rv --------
MMAR_0244|M.marinum_M --------
MUL_4869|M.ulcerans_Agy99 --------
Mvan_4082|M.vanbaalenii_PYR-1 --------
MSMEG_4708|M.smegmatis_MC2_155 --------
MAB_1294c|M.abscessus_ATCC_199 --------
MAV_0854|M.avium_104 IICRA---
Mflv_4877|M.gilvum_PYR-GCK VCVRATLA
TH_2193|M.thermoresistible__bu LVAIAVRP