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PAGQPWNINIHYDALLAATVAPGTQTALDVGCGDGFLSARLVDRVPDVTALDVDADVLRRAEHRFADTSI WWVHGDVMTGELPHRGFDAVLASASLHHIEGTRGALIRLAELVLPGGTLAVVTFVRPSPRNVLWHLTAWL ATGVANRVRRKWDHTAAIKWPPPVTFSQLRELVRELLPGARVRRLLYGRVLITWQAPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4869 | - | - | 100% (199) | methyltransferase/methylase |
| M. ulcerans Agy99 | MUL_1534 | - | 2e-07 | 34.02% (97) | hypothetical protein MUL_1534 |
| M. ulcerans Agy99 | MUL_0368 | - | 8e-06 | 36.00% (100) | hypothetical protein MUL_0368 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0092 | - | 2e-76 | 68.56% (194) | methyltransferase/methylase |
| M. gilvum PYR-GCK | Mflv_4877 | - | 5e-07 | 35.79% (95) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0089 | - | 2e-76 | 68.56% (194) | methyltransferase/methylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1294c | - | 1e-22 | 31.31% (198) | hypothetical protein MAB_1294c |
| M. marinum M | MMAR_0244 | - | 1e-109 | 95.48% (199) | methyltransferase/methylase |
| M. avium 104 | MAV_3889 | - | 2e-07 | 34.17% (120) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_4708 | - | 1e-19 | 32.83% (198) | putative methyltransferase |
| M. thermoresistible (build 8) | TH_0087 | - | 3e-07 | 31.43% (140) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_4082 | - | 2e-19 | 31.50% (200) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4869|M.ulcerans_Agy99 ---------------------MPAGQPWNINIHYDALLAATVAPGTQ---
MMAR_0244|M.marinum_M ---------------------MPAGQPWNINIHYDALLAATVAPGTQ---
Mb0092|M.bovis_AF2122/97 -----------------------MDQPWNANIHYDALLDAMVPLGTQ---
Rv0089|M.tuberculosis_H37Rv -----------------------MDQPWNANIHYDALLDAMVPLGTQ---
MSMEG_4708|M.smegmatis_MC2_155 ---------------------MPSPAYWNHNTAYHPWLRRIAAQHRG---
Mvan_4082|M.vanbaalenii_PYR-1 -----------------------MQDYWNHNTAYHPWLVGIAGEHRG---
MAB_1294c|M.abscessus_ATCC_199 ---------------------MPDHGRWNHNIHYQREVLRRVPAHAT---
MAV_3889|M.avium_104 MRAGDTRPAPGNLAAAFDAGAATYDRLVGASPGYHAQLLLSARRMRIPHD
Mflv_4877|M.gilvum_PYR-GCK --------MTAESDRRSLSFGAEAAAYERGRPSYPPEAIDWLLADSGS--
TH_0087|M.thermoresistible__bu ----------------------------MLTVDYDRLGIGPG--------
*
MUL_4869|M.ulcerans_Agy99 ----TALDVGCGDGFLSARLVDRVPDVTALDVDADV-------LRRAEHR
MMAR_0244|M.marinum_M ----TALDVGCGDGFLSARLADRVPDVTALDVDADV-------LRRAERR
Mb0092|M.bovis_AF2122/97 ----CVLDVGCGDGLLAARLARRIPYVTAVDIDAPV-------LRRAQTR
Rv0089|M.tuberculosis_H37Rv ----CVLDVGCGDGLLAARLARRIPYVTAVDIDAPV-------LRRAQTR
MSMEG_4708|M.smegmatis_MC2_155 ----DVLDVGCGDGLLAQRLAPVSRSVTAIEPDPQT-------LQRAWVR
Mvan_4082|M.vanbaalenii_PYR-1 ----DVLDIGCGDGLLAQRLLPVSRSVTLIDPDPDS-------VARAQAR
MAB_1294c|M.abscessus_ATCC_199 ----DVLDVGCGIGMLTRELAPLAQRVVGIDPHEPS-------LRIARAE
MAV_3889|M.avium_104 GKGLRLLDAGCGTGASTAALLAVAPAADIVAVDASRG------MLEVALA
Mflv_4877|M.gilvum_PYR-GCK -RRLEVLDLGAGTGKLTTRLVERGLDVVAVDPIPEM-------LDLLRTS
TH_0087|M.thermoresistible__bu ---VSVIDVGCGLGRHSFEAYRRGAHIVAFDQNAEELNEVDTILQAMAEQ
:* *.* * : . :
MUL_4869|M.ulcerans_Agy99 FA-DTSIWWVHGDVMTGELP--HRGFDAVLASASLHHIEGTRGALIRLAE
MMAR_0244|M.marinum_M FA-DTSIRWVHGDVMTGELP--HRGFDAVLANASLHHIEDTRGALIRLAE
Mb0092|M.bovis_AF2122/97 FA-NAPIRWLHADIMTAELP--NAGFDAVVSNAALHHIEDTRTALSRLGG
Rv0089|M.tuberculosis_H37Rv FA-NAPIRWLHADIMTAELP--NAGFDAVVSNAALHHIEDTRTALSRLGG
MSMEG_4708|M.smegmatis_MC2_155 LAHLPNVTVAQNDFDTFDPG--THRFDVVTMVATLHHMD-LRAALSKARE
Mvan_4082|M.vanbaalenii_PYR-1 LAGHADVSISQQSFHDYRPG--TALFDVITFVASLHHMA-LRESLRKARA
MAB_1294c|M.abscessus_ATCC_199 TS-ASNVEYVRGSFLEHPFP--AESFDLIAAVAALHHMD-IEQGLRRMSD
MAV_3889|M.avium_104 KRWPASVRFVHAPVQRLAEHGISGPFDGVLAAYLIRNVADRDEQLRRFRT
Mflv_4877|M.gilvum_PYR-GCK LP---DTPALLGTAEEIPLP--DDSVDAVLVAQAWHWFD-ETRAVKEIAR
TH_0087|M.thermoresistible__bu REAPAGARAEVVKGDALDLPYADGTFDRVIASEILEHVPEDDRAIAELVR
.* : . . : .
MUL_4869|M.ulcerans_Agy99 LVLPGGTLAVVT---------FVR-PSPRN------------VLWHLTAW
MMAR_0244|M.marinum_M LVLPAGTLAVVT---------FVR-PSLRN------------GLWHLTAW
Mb0092|M.bovis_AF2122/97 LVTPGGTLAVVT---------FVT-PSLRN------------GLWHLTSW
Rv0089|M.tuberculosis_H37Rv LVTPGGTLAVVT---------FVT-PSLRN------------GLWHLTSW
MSMEG_4708|M.smegmatis_MC2_155 LLTPTGEIAVVG---------LSANKTLRD------------WAWSGLCL
Mvan_4082|M.vanbaalenii_PYR-1 LLRPGGELAVVG---------LSANRSASD------------WIWSGLCL
MAB_1294c|M.abscessus_ATCC_199 LLKPGGRIVIVG---------FAANRSVTD------------LWYDGLGF
MAV_3889|M.avium_104 LLRPGATLAVHE---------YSVRDSAAAT-----------LAWHALCW
Mflv_4877|M.gilvum_PYR-GCK VLRPGGSLGLVW---------NNRDERLGWVKDLGDIIGHEGDPWSQSVE
TH_0087|M.thermoresistible__bu VLKPGGKLVVTVPRWLPERICWLLSDEYHANEGGHVRIYRADELRDKITR
:: * . : :
MUL_4869|M.ulcerans_Agy99 LATGVANRVRRKWDHTAAIKWPPPVTFSQLRELVRELLPGARVRRLLYGR
MMAR_0244|M.marinum_M LATGVANRVRRKWEHTAAIKWPPPVTFSQLRELVRELLPGARVRRLLYGR
Mb0092|M.bovis_AF2122/97 VACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRRLLYGR
Rv0089|M.tuberculosis_H37Rv VACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRRLLYGR
MSMEG_4708|M.smegmatis_MC2_155 PAVRLGSFCHRETRDIGVPVAEPAENLDEIRRVAADVLPGAMIRRALYYR
Mvan_4082|M.vanbaalenii_PYR-1 PAVRIGSRLHRETRDIGVVVAQPRESLREIRLVSDDVIPGAVVRRALYYR
MAB_1294c|M.abscessus_ATCC_199 WLHRYYRLRYGWWEHPSPVSCEGLDSHDEVRRIAQRVLPGARLQRLVLWR
MAV_3889|M.avium_104 GIIIPAGWWRSGDTALYRYLWRSVLAFDGATRFRARLADAGFT--AVHSE
Mflv_4877|M.gilvum_PYR-GCK LPAPFTGVERHHVEWTSYLTPQALIDLVASRSYCITSPERVRARTLDRVR
TH_0087|M.thermoresistible__bu HGLRLTHRHHAHALHSPFWWLKCAVGTNNDRHFAVRAYHQLLVWDMVRRP
MUL_4869|M.ulcerans_Agy99 VLITWQAPG-----------------------
MMAR_0244|M.marinum_M VLITWQAPG-----------------------
Mb0092|M.bovis_AF2122/97 VLVTWRAPV-----------------------
Rv0089|M.tuberculosis_H37Rv VLVTWRAPV-----------------------
MSMEG_4708|M.smegmatis_MC2_155 YLLRWQPAN-----------------------
Mvan_4082|M.vanbaalenii_PYR-1 YLLRWRKPA-----------------------
MAB_1294c|M.abscessus_ATCC_199 HLLTWEKS------------------------
MAV_3889|M.avium_104 TMPGWEAGIVHTFLADAPS-------------
Mflv_4877|M.gilvum_PYR-GCK ELLTTHPALANSSGLALPYVTVCVRATLA---
TH_0087|M.thermoresistible__bu WVTRWAEEMLNPLIGKSVALYFDKPEVAGADS
: