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VTSSTFWSAGRYDAVGDRIAPIAREVVDAADARRPLRDAAVVDLACGTGSAALDAAARGARVTGVDITPE LIAIAAERDGAAAVRWRTGDASDTGLPATSFDAAVSNMGIIFVEPARQVAEVVRLLKPGGVFAFSSWVRS VSNPLFDPVLAVLGPPATSTFSPDQWGDEAVLTERLGSQFDGVDVRRGDHRWEFESMPAAMRFLTSESPM HVETFRRAETSQRARLAAEFEDALRPHLEPSGSVAFLSPYVVVTATLRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4692 | - | - | 100% (259) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_4060 | - | 3e-23 | 31.82% (264) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_3090 | - | 8e-09 | 32.04% (181) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1440c | - | 3e-17 | 30.04% (243) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv1405c | - | 3e-17 | 30.04% (243) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 2e-14 | 29.10% (189) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_1977 | - | 1e-09 | 32.65% (98) | putative methyltransferase |
| M. marinum M | MMAR_1627 | - | 1e-16 | 30.04% (263) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 1e-15 | 30.73% (192) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_1893 | - | 2e-77 | 58.02% (262) | UbiE/COQ5 methyltransferase |
| M. thermoresistible (build 8) | TH_2937 | - | 1e-90 | 64.45% (256) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_3409 | - | 1e-16 | 29.66% (263) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1774 | - | 1e-106 | 74.03% (258) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1440c|M.bovis_AF2122/97 -MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAAG---
Rv1405c|M.tuberculosis_H37Rv -MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAAG---
MLBr_00551|M.leprae_Br4923 -MNLYTPIHEDQSLAAIHRAMWALGDYALMAEEVMAPLGPILVTATG---
MAV_3373|M.avium_104 -MTLDTTT-ADASVAARHRTVWALGDYALMAEEVMAPLGPTLVEAAG---
MMAR_1627|M.marinum_M MTTLARTEPTDRGYESKHRALWALGDYPAVATDLVSPLGPILLEATR---
MUL_3409|M.ulcerans_Agy99 MTTLARTEPTDRGYESKHRALWALGDYPAVATDLVSPLGPILLEATR---
Mflv_4692|M.gilvum_PYR-GCK ---------------MTSSTFWSAGRYDAVGDR-IAPIAREVVDAAD---
Mvan_1774|M.vanbaalenii_PYR-1 -------------MSVSSPSLWSAGRYDAVGQR-IAPIAEQVVDALD---
TH_2937|M.thermoresistible__bu ---------------VTTN--WAAGRYEAVGER-IAPIADEVLDAAA---
MSMEG_1893|M.smegmatis_MC2_155 -------------MPQPKPTNWAAGRYQAVAER-IAPIAEEVVVAAGRVG
MAB_1977|M.abscessus_ATCC_1997 -MDPAEHARHTRDVYDRLAPVWSATTDDGPFNGLLERPALRSLIPRP---
*: : . : .
Mb1440c|M.bovis_AF2122/97 ----IGPGVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAA
Rv1405c|M.tuberculosis_H37Rv ----IGPGVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAA
MLBr_00551|M.leprae_Br4923 ----IRPGMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARAT
MAV_3373|M.avium_104 ----IGPGVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRAA
MMAR_1627|M.marinum_M ----ISAGDRVLDVAAGSGNVAIPAALAGADVIASDLCPNLLECGRGLAA
MUL_3409|M.ulcerans_Agy99 ----ISAGDRVLDVAAGSGNVAIPAALAGADVIASDLCPNLLECGRGLAA
Mflv_4692|M.gilvum_PYR-GCK -ARRPLRDAAVVDLACGTGSAALDAAARGARVTGVDITPELIAIAAERDG
Mvan_1774|M.vanbaalenii_PYR-1 -RRQPLRGAAVVDLACGTGSAALAAAARGAQVTGVDLTPELIAIAAGREG
TH_2937|M.thermoresistible__bu -RRTPLRGATLVDLACGTGSAALSATARGAAVTGVDITSELIALAAGKPG
MSMEG_1893|M.smegmatis_MC2_155 PQRGPLTGGDIVDLACGTGSAALAAAAAGADVTGVDITPELIDIAKTRPG
MAB_1977|M.abscessus_ATCC_1997 -----LAGRSVLDAGCGSGAQCAWLLGEGADVTGLDLSPAMVDQARQRCG
. ::* ..*:* ** : . *: . :: .
Mb1440c|M.bovis_AF2122/97 QQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVCR
Rv1405c|M.tuberculosis_H37Rv QQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVCR
MLBr_00551|M.leprae_Br4923 ELGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRRAASELVRVCR
MAV_3373|M.avium_104 GMGLTIDYREANAQALPFGDGEFDAVVSAIGVQFAPDHQRAADELVRVCR
MMAR_1627|M.marinum_M ARGASLRWVEANAQALPFDTDEFDAVVSCVGVMFAPYHQPCADELVRVCR
MUL_3409|M.ulcerans_Agy99 ARGASLRWVEANAQALPFDTDEFDAVVSCVGVMFAPYHQPCADGLVRVCR
Mflv_4692|M.gilvum_PYR-GCK AA--AVRWRTGDASDTGLPATSFDAAVSNMGIIFVEPAR-QVAEVVRLLK
Mvan_1774|M.vanbaalenii_PYR-1 AD--AVTWRTADASDTGLPAGAFDAAVSNMGIIFVDPDR-QVAEIARLLK
TH_2937|M.thermoresistible__bu GS--TVTWVTADAADTGLKTASFDVAVSNMGIIFVPPDR-QVAELARLLK
MSMEG_1893|M.smegmatis_MC2_155 GD--QVTWVAADATRTGLPDGGFDAAVSNMGIIFVEPTG-LVAEVARLLR
MAB_1977|M.abscessus_ATCC_1997 SA--AKLMVADLADDLPLEPRSFDGVTCSLALHYLRDWQVPLASFARILR
* : ** . . :.: : ..*: :
Mb1440c|M.bovis_AF2122/97 PGGTIGVISWTCEG---FFGRMLATIRPYRPSVSADLPPSALWGREAYVT
Rv1405c|M.tuberculosis_H37Rv PGGTIGVISWTCEG---FFGRMLATIRPYRPSVSADLPPSALWGREAYVT
MLBr_00551|M.leprae_Br4923 PNGTIGVISWTQEG---FFGRMLATIRPYRPSLSAALPPAALWGREAYIR
MAV_3373|M.avium_104 PGGRIGLISWTPEG---FFGRMLATIRPYRPSLSHPVPPAALWGRPGYVR
MMAR_1627|M.marinum_M PGGVIGLISWTPGG---FIGEMFTTMKPYLAPPLPGAQPAPLWGTEGHVR
MUL_3409|M.ulcerans_Agy99 PGGVIGLISWTPGG---FIGEMFTTMKPYLAPPLPGAQPAPLWGTEGHVR
Mflv_4692|M.gilvum_PYR-GCK PGGVFAFSSWVRSV----SNPLFDPVLAVLGPPATSTFSPDQWGDEAVLT
Mvan_1774|M.vanbaalenii_PYR-1 PAGRLAFSAWARDA----DNPFFDPVVAVLGPPPATGFSPDQWGDTDTLT
TH_2937|M.thermoresistible__bu PGGVLSFSAWIRTD----ENPFSDPVAEVLGPPPAG-FSPDQWGDAETLT
MSMEG_1893|M.smegmatis_MC2_155 PGGVFAFSAWVRDDRDGAENPFFAPIVEVLGPPSAAAFTPDQWGDRDVVA
MAB_1977|M.abscessus_ATCC_1997 PGG------WVVIS---LDHPFGAPLPDQRGGYFQHQLVSDTWNKADVEV
* * * : .: . *.
Mb1440c|M.bovis_AF2122/97 GLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNA
Rv1405c|M.tuberculosis_H37Rv GLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNA
MLBr_00551|M.leprae_Br4923 GLLDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYTNIGDNS
MAV_3373|M.avium_104 ALLGERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIGHNR
MMAR_1627|M.marinum_M ELFADRVTDFAVRRGALLVDEFADGASFRDYFKANYGPTIAAYRAIAAEP
MUL_3409|M.ulcerans_Agy99 ELFADRVTDFAVRRGTLLVDEFADGASFRDYFKANYGPTIAAYRAIAAEP
Mflv_4692|M.gilvum_PYR-GCK ERLGSQFDGVDVRRG-DHRWEFESMPAAMRFLTSESPMHVETFRRAETSQ
Mvan_1774|M.vanbaalenii_PYR-1 TRLAPFFDDIDVQRA-RHRWEFESMAAALHFLRSESPMHVATFRRAAPAQ
TH_2937|M.thermoresistible__bu ERLTPHFDAIDLIRG-LHPWEFDSPATALHFLRTESPVHVEIFRRAGPAR
MSMEG_1893|M.smegmatis_MC2_155 QRLAAHFGDITVETS-DLTWNFASLAAAMEFLEFESPAHVSLFQSLDTPV
MAB_1977|M.abscessus_ATCC_1997 T---------------QHFWRRPLGQVADAFADAG----LLIERISEPRP
. : :
Mb1440c|M.bovis_AF2122/97 VLAAELDRQLVELAAQYLS-DGVMEWEYLLLTAEKR--
Rv1405c|M.tuberculosis_H37Rv VLAAELDRQLVELAAQYLS-DGVMEWEYLLLTAEKR--
MLBr_00551|M.leprae_Br4923 VLAAELDAQLTELAQKYLT-NSTMGWEYLLLTAQKH--
MAV_3373|M.avium_104 VLAAELDAQLVELAAQHLS-DGTMGWEYLLVTAEKRSG
MMAR_1627|M.marinum_M DRVAALDAELAALGDRYLAGSSAMEWEYLLVTARKR--
MUL_3409|M.ulcerans_Agy99 DRVAALDAELAALGDRYLAGSSAMEWEYLLVTARKR--
Mflv_4692|M.gilvum_PYR-GCK RARLAAEFEDALRPHLEPSGSVAFLSPYVVVTATLRG-
Mvan_1774|M.vanbaalenii_PYR-1 QDRLAAEFEIALRRHLEPSGAVAFTAPYVVVSATLRA-
TH_2937|M.thermoresistible__bu RERLAAAFRSALRPHAGPAGTVGFTAPYVIVTARRRG-
MSMEG_1893|M.smegmatis_MC2_155 RDRLRSVFEAALRRHVDTTGTVAFASPYLVTTALRR--
MAB_1977|M.abscessus_ATCC_1997 SAEAIRRFPAELRNVVDSPSFIVYRLRYWGAPA-----
. * .*