For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VPSPAYWNHNTAYHPWLRRIAAQHRGDVLDVGCGDGLLAQRLAPVSRSVTAIEPDPQTLQRAWVRLAHLP NVTVAQNDFDTFDPGTHRFDVVTMVATLHHMDLRAALSKARELLTPTGEIAVVGLSANKTLRDWAWSGLC LPAVRLGSFCHRETRDIGVPVAEPAENLDEIRRVAADVLPGAMIRRALYYRYLLRWQPAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4708 | - | - | 100% (200) | putative methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2632 | - | 7e-06 | 32.38% (105) | SAM-dependent methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 4e-05 | 30.00% (120) | hypothetical protein MSMEG_2350 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0092 | - | 2e-21 | 36.98% (192) | methyltransferase/methylase |
| M. gilvum PYR-GCK | Mflv_4877 | - | 7e-06 | 26.83% (123) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0089 | - | 2e-21 | 36.98% (192) | methyltransferase/methylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1294c | - | 1e-29 | 36.27% (204) | hypothetical protein MAB_1294c |
| M. marinum M | MMAR_0244 | - | 5e-22 | 34.34% (198) | methyltransferase/methylase |
| M. avium 104 | MAV_0854 | - | 1e-06 | 38.24% (102) | methyltransferase-UbiE family protein |
| M. thermoresistible (build 8) | TH_1968 | - | 6e-06 | 28.46% (123) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_4869 | - | 7e-20 | 32.83% (198) | methyltransferase/methylase |
| M. vanbaalenii PYR-1 | Mvan_4082 | - | 6e-76 | 68.75% (192) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0092|M.bovis_AF2122/97 -------------------MDQPWNANIHYDALLDAMVPLGTQCVLDVGC
Rv0089|M.tuberculosis_H37Rv -------------------MDQPWNANIHYDALLDAMVPLGTQCVLDVGC
MMAR_0244|M.marinum_M -----------------MPAGQPWNINIHYDALLAATVAPGTQTALDVGC
MUL_4869|M.ulcerans_Agy99 -----------------MPAGQPWNINIHYDALLAATVAPGTQTALDVGC
MSMEG_4708|M.smegmatis_MC2_155 -----------------MPSPAYWNHNTAYHPWLRRIAAQHRGDVLDVGC
Mvan_4082|M.vanbaalenii_PYR-1 -------------------MQDYWNHNTAYHPWLVGIAGEHRGDVLDIGC
MAB_1294c|M.abscessus_ATCC_199 -----------------MPDHGRWNHNIHYQREVLRRVPAHATDVLDVGC
Mflv_4877|M.gilvum_PYR-GCK MTAESDRRSLSFGAEAAAYERGRPSYPPEAIDWLLADSGSRRLEVLDLGA
TH_1968|M.thermoresistible__bu ---------LSFGAEAAAYERGRPSYPPEAIDWLLP-SDAR--DVLDLGA
MAV_0854|M.avium_104 -MNDQHRATYTHGHHESVLRSHRRRTAEDSAGYLLAHLTPG-LSVLDVGC
: .**:*.
Mb0092|M.bovis_AF2122/97 GDGLLAARLARRIPY--VTAVDIDAPVLRRAQTRFA---NAPIRWLHADI
Rv0089|M.tuberculosis_H37Rv GDGLLAARLARRIPY--VTAVDIDAPVLRRAQTRFA---NAPIRWLHADI
MMAR_0244|M.marinum_M GDGFLSARLADRVPD--VTALDVDADVLRRAERRFA---DTSIRWVHGDV
MUL_4869|M.ulcerans_Agy99 GDGFLSARLVDRVPD--VTALDVDADVLRRAEHRFA---DTSIWWVHGDV
MSMEG_4708|M.smegmatis_MC2_155 GDGLLAQRLAPVSRS--VTAIEPDPQTLQRAWVRLAH--LPNVTVAQNDF
Mvan_4082|M.vanbaalenii_PYR-1 GDGLLAQRLLPVSRS--VTLIDPDPDSVARAQARLAG--HADVSISQQSF
MAB_1294c|M.abscessus_ATCC_199 GIGMLTRELAPLAQR--VVGIDPHEPSLRIARAETS---ASNVEYVRGSF
Mflv_4877|M.gilvum_PYR-GCK GTGKLTTRLVERGLD--VVAVDPIPEMLDLLRTSLP-----DTPALLGTA
TH_1968|M.thermoresistible__bu GTGKLTTRLVERGLN--VTAVDPIPEMLELLSKSLP-----DTPALLGTA
MAV_0854|M.avium_104 GPGTITADLAARVAPGQVTAVDQAADVLEVARAEAEQRNLSNVSFGTADV
* * :: * *. :: :
Mb0092|M.bovis_AF2122/97 MTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVT----
Rv0089|M.tuberculosis_H37Rv MTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVT----
MMAR_0244|M.marinum_M MTGELPHRGFDAVLANASLHHIEDTRGALIRLAELVLPAGTLAVVT----
MUL_4869|M.ulcerans_Agy99 MTGELPHRGFDAVLASASLHHIEGTRGALIRLAELVLPGGTLAVVT----
MSMEG_4708|M.smegmatis_MC2_155 DTFDPGTHRFDVVTMVATLHHMD-LRAALSKARELLTPTGEIAVVG----
Mvan_4082|M.vanbaalenii_PYR-1 HDYRPGTALFDVITFVASLHHMA-LRESLRKARALLRPGGELAVVG----
MAB_1294c|M.abscessus_ATCC_199 LEHPFPAESFDLIAAVAALHHMD-IEQGLRRMSDLLKPGGRIVIVG----
Mflv_4877|M.gilvum_PYR-GCK EEIPLPDDSVDAVLVAQAWHWFD-ETRAVKEIARVLRPGGSLGLVWNNRD
TH_1968|M.thermoresistible__bu EEIPLPDNSVDAVLVAQAWHWFD-VDRAVREVARVLRPGGRLGLVWNTRD
MAV_0854|M.avium_104 HRLDFADDTFDVVHAHQVLQHLSDPVAALREMRRVCRPGGIVAVRDADYA
.* : : : .: . : * * : :
Mb0092|M.bovis_AF2122/97 --------FVT-PSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQ
Rv0089|M.tuberculosis_H37Rv --------FVT-PSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQ
MMAR_0244|M.marinum_M --------FVR-PSLRNGLWHLTAWLATGVANRVRRKWEHTAAIKWPPPV
MUL_4869|M.ulcerans_Agy99 --------FVR-PSPRNVLWHLTAWLATGVANRVRRKWDHTAAIKWPPPV
MSMEG_4708|M.smegmatis_MC2_155 --------LSANKTLRDWAWSGLCLPAVRLGSFCHRETRDIGVPVAEPAE
Mvan_4082|M.vanbaalenii_PYR-1 --------LSANRSASDWIWSGLCLPAVRIGSRLHRETRDIGVVVAQPRE
MAB_1294c|M.abscessus_ATCC_199 --------FAANRSVTDLWYDGLGFWLHRYYRLRYGWWEHPSPVSCEGLD
Mflv_4877|M.gilvum_PYR-GCK ERLGWVKDLGDIIGHEGDPWSQSVELPAPFTGVERHHVEWTSYLTPQALI
TH_1968|M.thermoresistible__bu ERMGWVKELGRIIGDEHDPLSKTVTLPEPFTDVQRHQVEWTNYLTPQALI
MAV_0854|M.avium_104 G--FIWYPELPALDLWRDLYRRVARANRGEPDAGRRLLSWARQAGFDDIT
Mb0092|M.bovis_AF2122/97 TLHELRSHVRALL----PGACIRRLLY---GRVLVTWRAPV---------
Rv0089|M.tuberculosis_H37Rv TLHELRSHVRALL----PGACIRRLLY---GRVLVTWRAPV---------
MMAR_0244|M.marinum_M TFSQLRELVRELL----PGARVRRLLY---GRVLITWQAPG---------
MUL_4869|M.ulcerans_Agy99 TFSQLRELVRELL----PGARVRRLLY---GRVLITWQAPG---------
MSMEG_4708|M.smegmatis_MC2_155 NLDEIRRVAADVL----PGAMIRRALY---YRYLLRWQPAN---------
Mvan_4082|M.vanbaalenii_PYR-1 SLREIRLVSDDVI----PGAVVRRALY---YRYLLRWRKPA---------
MAB_1294c|M.abscessus_ATCC_199 SHDEVRRIAQRVL----PGARLQRLVL---WRHLLTWEKS----------
Mflv_4877|M.gilvum_PYR-GCK DLVASRSYCITSP----ERVRARTLDR---VRELLTTHPALANSSGLALP
TH_1968|M.thermoresistible__bu DLVASRSYCITSP----AKVRARTLER---VRELLATHPALANNSGLALP
MAV_0854|M.avium_104 PTGSLWCYATPETRDWWGGMWADRILHSTVARDLVSLGLAAREQLEEISA
* *: .
Mb0092|M.bovis_AF2122/97 ------------------------
Rv0089|M.tuberculosis_H37Rv ------------------------
MMAR_0244|M.marinum_M ------------------------
MUL_4869|M.ulcerans_Agy99 ------------------------
MSMEG_4708|M.smegmatis_MC2_155 ------------------------
Mvan_4082|M.vanbaalenii_PYR-1 ------------------------
MAB_1294c|M.abscessus_ATCC_199 ------------------------
Mflv_4877|M.gilvum_PYR-GCK YVTVCVRATLA-------------
TH_1968|M.thermoresistible__bu YITVCIRATLA-------------
MAV_0854|M.avium_104 AWREWAAAPDGWIAIPHGEIICRA