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HYGIDGRSALVVGGSKGIGFEVAKLLAAEGARVAILARTKTDVDAAVEAIRTEGGTAIGVTADVADDGQL TDAVREIAARHGAPLIVVGQAKYQRPGDFADITDVNVYRESFELHTMSQILLLHAVLPAMQDAGWGRFVH IGSATAKEPAGNIHHAVANTSRPSTIGLLKTVSDEYAQFGITVNTVAPGWIETENALAYLEQHLGASTDQ ERREFMLREARVPAARMGKPSEIASLIAYLCSEPAGYLTGSWIEVDGGLHRSAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2549 | - | - | 100% (265) | short-chain dehydrogenase/reductase SDR |
| M. avium 104 | MAV_1809 | - | e-125 | 81.51% (265) | short-chain dehydrogenase/reductase SDR |
| M. avium 104 | MAV_2438 | - | 8e-32 | 35.21% (267) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 3e-24 | 30.89% (259) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0296 | - | 8e-30 | 30.97% (268) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1928c | - | 3e-24 | 30.89% (259) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-21 | 29.46% (258) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 5e-26 | 30.60% (268) | short chain dehydrogenase |
| M. marinum M | MMAR_1568 | - | 2e-30 | 33.46% (269) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_0294 | fabG | 1e-31 | 34.90% (255) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3893 | - | 2e-30 | 32.23% (273) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 8e-28 | 35.04% (254) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_0398 | - | 4e-28 | 34.36% (259) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2549|M.avium_104 --------------MHYGIDGRSALVVGGSKGIGFEVAKLLAAEGARVAI
MMAR_1568|M.marinum_M --------------MDLGFSGSKAVVTGGSKGMGLAIAETLAAEGASVAV
Mflv_0296|M.gilvum_PYR-GCK --------------MDMGLSGKRALVTGSSSGLGRAIAESLAAEGASVVV
TH_3893|M.thermoresistible__bu --------------MDFDLNGKRALVTGSSSGIGAGIVETLAAEGVSVVV
Mvan_0398|M.vanbaalenii_PYR-1 --------------MKIDLTGKTALVTGSTQGIGLAIARSLAASGARVAV
Mb1963c|M.bovis_AF2122/97 --MSVLD--------LFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv --MSVLD--------LFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MAB_0952|M.abscessus_ATCC_1997 --MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAV
MSMEG_0294|M.smegmatis_MC2_155 -------------------MNRVAVVTGGASGMGEATCHELGRRGHKVAV
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
::.*. *:* * *.
MAV_2549|M.avium_104 LARTKTDVDAAVEAIRTEGG-TAIGVTADVADDGQLTDAVREIAARHGAP
MMAR_1568|M.marinum_M IARGKRALDSAVERLSQAGAPDAVAISADMADAASITSAFAAVSERWGQL
Mflv_0296|M.gilvum_PYR-GCK HGRDEVRTGAVADGIRARGG-DAWAAVGDLATEGGAGAVAAAAG----EV
TH_3893|M.thermoresistible__bu HGRNAERAEAVADRIRADGG-TAATAVGDLATEDGAAQVADTAAAAFSGI
Mvan_0398|M.vanbaalenii_PYR-1 NGRSRDR---VDEAVATLDG-DVVGVAADVADAAGAQALAAELP----HI
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGAL
MSMEG_0294|M.smegmatis_MC2_155 LDVDVDAAQRVTDHLRSEG-VTAFAVGADVTDRAAVEEAFAKVRSELGAV
MUL_0315|M.ulcerans_Agy99 LDLKTPDGG--------------LAFSADVTNRSQVDAALAAIRQRLGPV
MLBr_01807|M.leprae_Br4923 THRASVVPD------------WFFGVECDVTDNDAIGAAFKAVEEHQGPV
*::
MAV_2549|M.avium_104 LIVVGQAKYQRP---GDFADITDVNVYRESFELHTMSQILLLHAVLPAMQ
MMAR_1568|M.marinum_M NCLVHTIGPGD----GYFEELDDA-AWDAAFTLGTMSGVRAIRAALPLLR
Mflv_0296|M.gilvum_PYR-GCK DILVNNAGVYDG---LAWSDLAPR-QWQSIYEVNVVSGVRMIEYLVPGMR
TH_3893|M.thermoresistible__bu DILVNNAGGSSETGIQSWFALPVS-EWGVTYQRNVMSAGYLIHALVPAMK
Mvan_0398|M.vanbaalenii_PYR-1 DILVNNLGIFGA---VPAREITDD-QWRSYFEVNVLAAARLIRHYLPGMV
Mb1963c|M.bovis_AF2122/97 DIAVCNAGIITV---TPMLDMPLE-EFQRLQNTNVTGVFLTAQAAAKAMV
Rv1928c|M.tuberculosis_H37Rv DIAVCNAGIITV---TPMLDMPLE-EFQRLQNTNVTGVFLTAQAAAKAMV
MAB_0952|M.abscessus_ATCC_1997 DVVCANAGIFPE---ARLDTMTPE-QLSEVLDVNVKGTVYTVQACLAPLT
MSMEG_0294|M.smegmatis_MC2_155 GILVTSAGMFGY---ASFADITEQ-SWAQMIDVNLSGTFRCCQVALPDMV
MUL_0315|M.ulcerans_Agy99 TILVNAAGLDGF---KRFSNITFE-DWQRVIDVNLNGVFHTIQAVLPDMV
MLBr_01807|M.leprae_Br4923 EVLVANAGITSD---MLIMRMSEE-QFQKVIDVNLTGVFRVAKLASRNMI
: . . :
MAV_2549|M.avium_104 DAGWGRFVHIGSATAKEPA-GNIHHAVANTSRPSTIGLLKTVSDEYAQFG
MMAR_1568|M.marinum_M AADWARVVTLSAHSIQR---QNPRLVAYTASKAALSSVTKNLSKSLAKEG
Mflv_0296|M.gilvum_PYR-GCK QRGWGRIIQIGGGLALQP---AADQPHYNATLAARHNLTVSLARELAGTG
TH_3893|M.thermoresistible__bu ESGWGRIIQIASAAGIIP---TSGQPDYGPSKAAMINMSMGLSKALAGTG
Mvan_0398|M.vanbaalenii_PYR-1 DRGWGRVLQIASDSAIVI---PEEMIHYGVSKTALLALSRGFAKDASGTG
Mb1963c|M.bovis_AF2122/97 KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK
Rv1928c|M.tuberculosis_H37Rv KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK
MAB_0952|M.abscessus_ATCC_1997 ASGRGRVIL-TSSITGPVTGYPG-WSHYGASKAAQLGFMRTAAIELAPRG
MSMEG_0294|M.smegmatis_MC2_155 DAGWGRIVLISSSSA---QRGTPFAAHYAASKGALLTLTKSLAREYAKHG
MUL_0315|M.ulcerans_Agy99 AAGWGRIVNISSSST---HSGTPYMTHYVAAKSAVNGLTKALALEYGPSG
MLBr_01807|M.leprae_Br4923 KQRFGRYIFMGSVVG---LSGVPGQANYAASKSGLIGMARSLARELGSRS
. : . : . . : .
MAV_2549|M.avium_104 ITVNTVAPGWIETENALAYLEQHLGASTDQERREFMLR-------EARVP
MMAR_1568|M.marinum_M ILVNCVCPGTIVTASFTEQLKDLLAADGLDATNPYDVMAWIDKYFHQPCD
Mflv_0296|M.gilvum_PYR-GCK VTSNTVAPGAILTEPVREMTYRVAAQRGWGPTWEDVEKAAATTWFPN--D
TH_3893|M.thermoresistible__bu ITVNTVMPGMIMTEGLRDFLRTFADHRGWG---DDLDKAADYILKGTGQT
Mvan_0398|M.vanbaalenii_PYR-1 VTVNSVIAGPTHTAGVEDFVYQLVDK---SLPWEQAQREFMRLHRPQ-SL
Mb1963c|M.bovis_AF2122/97 IRVNSVSPGYILTE-LVEPYTE------------------YQPLWEPKIP
Rv1928c|M.tuberculosis_H37Rv IRVNSVSPGYILTE-LVEPYTE------------------YQPLWEPKIP
MAB_0952|M.abscessus_ATCC_1997 VTVNAILPGNILTEGLVDMGEE------------------YISGMARSIP
MSMEG_0294|M.smegmatis_MC2_155 ITVNNIPPSGIETPMQHASQAAGYLP--------------PNETIAANIP
MUL_0315|M.ulcerans_Agy99 ITVNAVPPGFIDTPMLRNAAAQGHLG--------------DIEQNIARTP
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTRAMDSK------------------YQEAALQAIP
: * : .. *
MAV_2549|M.avium_104 AARMGKPSEIASLIAYLCSEPAGYLTGSWIEVDGGLHRSAF------
MMAR_1568|M.marinum_M LGRAGLPEEVASITAYLVSRRNGYVTGATVNADGGSDFI--------
Mflv_0296|M.gilvum_PYR-GCK IGRFGRPEEVAAAVAFLAGVHAGYISGADLRVDGGAIRSVA------
TH_3893|M.thermoresistible__bu VHRIGQVSDVAYAVAFLASPRADFLNGINLHLDGGATQSIY------
Mvan_0398|M.vanbaalenii_PYR-1 IERLIEPEEIANMVTYLASPLASATTGGALRVDGGYVDAILP-----
Mb1963c|M.bovis_AF2122/97 LGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP--------
Rv1928c|M.tuberculosis_H37Rv LGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP--------
MAB_0952|M.abscessus_ATCC_1997 MGMLGSPVDIGHLAAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP
MSMEG_0294|M.smegmatis_MC2_155 LGRLGAPADIAAAVGFLCSEEAGFITGQTLGVNGGSVM---------
MUL_0315|M.ulcerans_Agy99 VRRIGKPEDIAAACAFLVSEEAGYITGQILGVNGGRNT---------
MLBr_01807|M.leprae_Br4923 LGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-------
::. :* . .* : :**