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DLGFSGSKAVVTGGSKGMGLAIAETLAAEGASVAVIARGKRALDSAVERLSQAGAPDAVAISADMADAAS ITSAFAAVSERWGQLNCLVHTIGPGDGYFEELDDAAWDAAFTLGTMSGVRAIRAALPLLRAADWARVVTL SAHSIQRQNPRLVAYTASKAALSSVTKNLSKSLAKEGILVNCVCPGTIVTASFTEQLKDLLAADGLDATN PYDVMAWIDKYFHQPCDLGRAGLPEEVASITAYLVSRRNGYVTGATVNADGGSDFI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1568 | - | - | 100% (267) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_4715 | - | 9e-26 | 31.91% (257) | 3-oxoacyl- |
| M. marinum M | MMAR_4033 | fabG | 2e-24 | 29.34% (259) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 5e-24 | 31.18% (263) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4353 | - | 2e-69 | 51.49% (268) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 5e-24 | 31.18% (263) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-17 | 26.89% (264) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 6e-25 | 31.18% (263) | Short-chain dehydrogenase/reductase |
| M. avium 104 | MAV_2438 | - | 1e-122 | 80.52% (267) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_2228 | - | 4e-76 | 54.48% (268) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. thermoresistible (build 8) | TH_4608 | - | 3e-70 | 51.67% (269) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 2e-26 | 31.91% (257) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_1991 | - | 1e-68 | 51.12% (268) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MAB_0833|M.abscessus_ATCC_1997 -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MUL_0315|M.ulcerans_Agy99 ---------MRPD-SSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MMAR_1568|M.marinum_M --------------MDLGFSGSKAVVTGGSKGMGLAIAETLAAEGASVAV
MAV_2438|M.avium_104 --------------MDLGLAGSTAVVTGGSKGMGLAVAETLAAEGAKVAV
Mflv_4353|M.gilvum_PYR-GCK --------------MDLGLRDATVVVVGGGRGMGLAAAHCFADDGARVAL
Mvan_1991|M.vanbaalenii_PYR-1 --------------MDLGLRDATAVVVGGGRGMGLAAAHCFADDGARVAL
TH_4608|M.thermoresistible__bu --------------MDLGFTDAAAVVVGGGRGMGLAAAQCLADDGARVAV
MSMEG_2228|M.smegmatis_MC2_155 --------------MDLGFGGAAAAVVGGGRGMGFATAQCLADDGARVAV
:.*. *:* * *. * *.
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQV----GDRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQV----GDRALGVGAHAVDEDAARRCVDLTLERFGSV
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLR-SLGARALGVPTHTGDIHSLEELVRATAEEFGGI
MLBr_01807|M.leprae_Br4923 THRAS------------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
MUL_0315|M.ulcerans_Agy99 LDLK--------------TPDGGLAFSADVTNRSQVDAALAAIRQRLGPV
MMAR_1568|M.marinum_M IARGKRALDSAVERLSQAGAPDAVAISADMADAASITSAFAAVSERWG-Q
MAV_2438|M.avium_104 MARGRHALDAAVALLREAGAPDAVGVSVDMADAESIADGFAAVAQRWG-R
Mflv_4353|M.gilvum_PYR-GCK VGRTRDVLDEAAAQLRGRGSPDAVGVVADCADEAAVQRAFGELAERWNGE
Mvan_1991|M.vanbaalenii_PYR-1 IGRSPEVLDGAAAQLRERGSPDAVGVVADTTDDAAVRRAFAELGERWNGE
TH_4608|M.thermoresistible__bu IGRTRSMLDEAAADLARRGSPDALGIVADIRDEQQVERVFAELGERWQGE
MSMEG_2228|M.smegmatis_MC2_155 IGRSKDVLETAASDLARRGSPDAIAIVADTGDAEQVERAFAEIGERWDGE
... . : . :.
Mb2788c|M.bovis_AF2122/97 DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
Rv2766c|M.tuberculosis_H37Rv DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
MAB_0833|M.abscessus_ATCC_1997 DIVVNNA-ANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDML-IMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MUL_0315|M.ulcerans_Agy99 TILVNAAGLDGFKR-FSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
MMAR_1568|M.marinum_M LNCLVHTIGPGD-GYFEELDDAAWDAAFTLGTMSGVRAIRAALPLLRAAD
MAV_2438|M.avium_104 LNSLVHTIGPGD-GDFEELDDTGWDEAFALGTMSAVRSIRNALPLLRAAD
Mflv_4353|M.gilvum_PYR-GCK LNVLVNAVGPTVRGTFDELSDADWRQAVDEGAMGMVRCVRAALPLLRAAE
Mvan_1991|M.vanbaalenii_PYR-1 LNILVNAVGPTVRGTFDELTDADWRQAVDEGAMGMVHCVRAALPLLRAAE
TH_4608|M.thermoresistible__bu LNVLINTVGPAVMGTVEELSDEQWRSAVDDGVLGMVHCVRSALPLLRQAE
MSMEG_2228|M.smegmatis_MC2_155 LNVLINTVGPGAAGDFEELTDGQWQEAFDAGVMGMVRCVRAALPLLRKAE
: : . : . . . . .
Mb2788c|M.bovis_AF2122/97 GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAI
Rv2766c|M.tuberculosis_H37Rv GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAI
MAB_0833|M.abscessus_ATCC_1997 HAAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNAL
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MUL_0315|M.ulcerans_Agy99 WGRIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAV
MMAR_1568|M.marinum_M WARVVTLSAHSIQRQNPRLVAYTASKAALSSVTKNLSKSLAKEGILVNCV
MAV_2438|M.avium_104 WGRIVTFAAHSIQRQNPRIVAYTASKAALASITKNLSKSLAAEGILVNCV
Mflv_4353|M.gilvum_PYR-GCK WARIVNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVV
Mvan_1991|M.vanbaalenii_PYR-1 WARIVNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVV
TH_4608|M.thermoresistible__bu WARIVNLSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLAKDEILVNVV
MSMEG_2228|M.smegmatis_MC2_155 WARIVNFSAHSTQRQSTRLPAYTAAKAAVNSVSKNLSLLLAKDEIMVNVV
. : : * *:*: : :: : . : .* :
Mb2788c|M.bovis_AF2122/97 CPGVVRT--------------RLAEALWKD----HEDPLAATIALGRIGE
Rv2766c|M.tuberculosis_H37Rv CPGVVRT--------------RLAEALWKD----HEDPLAATIALGRIGE
MAB_0833|M.abscessus_ATCC_1997 APGAIDT--------------DMVRKTPPA----EVERMANTNHLKRLGL
MLBr_01807|M.leprae_Br4923 APGFIDT--------------EMTRAMDSK----YQEAALQAIPLGRIGA
MUL_0315|M.ulcerans_Agy99 PPGFIDT--------------PMLRNAAAQGHLGDIEQNIARTPVRRIGK
MMAR_1568|M.marinum_M CPGTIVTASFTEQLKDLLAADGLDATNPYDVMAWIDKYFHQPCDLGRAGL
MAV_2438|M.avium_104 CPGTIVTASFTEALKGVLAADGLDATDPVDVMTWIDDNFHQPCDLGRAGL
Mflv_4353|M.gilvum_PYR-GCK SPGSIAS----EALVGWADSVGVDGSDPYALMAAIDEHFGHPAHLPRAGL
Mvan_1991|M.vanbaalenii_PYR-1 SPGSIAS----EALLGWADSVGVDGSDPYALMAAIDEHFGHPAHLPRAGL
TH_4608|M.thermoresistible__bu SPGSIAS----EALVGWADSIGVDGTDPYALMSAIDEHFGHPAHLPRAGL
MSMEG_2228|M.smegmatis_MC2_155 SPGSISS----EALVGWAESVGVDGSDPYQLMAAIDEHFGHPAHLPRAGL
** : : : . : * *
Mb2788c|M.bovis_AF2122/97 PADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv PADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
MAB_0833|M.abscessus_ATCC_1997 PDEMVGTALLLTSDAGSYITGQTIIADGGLVAR-------------
MLBr_01807|M.leprae_Br4923 VEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH------------
MUL_0315|M.ulcerans_Agy99 PEDIAAACAFLVSEEAGYITGQILGVNGGRNT--------------
MMAR_1568|M.marinum_M PEEVASITAYLVSRRNGYVTGATVNADGGSDFI-------------
MAV_2438|M.avium_104 PEEVASITVYLASRRNGYVTGAMVNVDGGSDFI-------------
Mflv_4353|M.gilvum_PYR-GCK PTEIGSVVAFLASRRNSYMTGADINVDGGSDFT-------------
Mvan_1991|M.vanbaalenii_PYR-1 PTEIGPVVAFLASRRNSYMTGANINVDGGSDFT-------------
TH_4608|M.thermoresistible__bu PEEIGPVIAFLASRRNSYMTGANVNVDGGSDFV-------------
MSMEG_2228|M.smegmatis_MC2_155 PSEIGPVAAFLASRRNSYMTGANINVDGGSDFT-------------
:: *.* .:::* : :**