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M. thermoresistible (build 8) TH_3893 (-)

annotation: putative short-chain dehydrogenase/reductase SDR
coordinates: 233750 - 234559
length: 270

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3893--100% (270)putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_4266-2e-3031.03% (261) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3898-4e-2833.58% (265) PUTATIVE short chain dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0950c-9e-3033.71% (264) short chain dehydrogenase
M. gilvum PYR-GCKMflv_0296-7e-6149.08% (271) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0927c-9e-3033.71% (264) short chain dehydrogenase
M. leprae Br4923MLBr_02565fabG5e-2128.84% (267) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4665c-4e-3132.93% (246) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_4581-2e-2732.58% (264) short-chain type dehydrogenase/reductase
M. avium 104MAV_2549-3e-3032.23% (273) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155MSMEG_0600-2e-3636.06% (269) dehydrogenase
M. ulcerans Agy99MUL_4442-7e-2732.20% (264) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_0398-2e-3434.72% (265) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
TH_3893|M.thermoresistible__bu      --------------------------------------------------
Mflv_0296|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0600|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0398|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4665c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2549|M.avium_104                --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
                                                                                      

Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
TH_3893|M.thermoresistible__bu      --------------------------------------------------
Mflv_0296|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0600|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0398|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4665c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2549|M.avium_104                --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
                                                                                      

Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
TH_3893|M.thermoresistible__bu      --------------------------------------------------
Mflv_0296|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0600|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0398|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4665c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2549|M.avium_104                --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
                                                                                      

Mb0950c|M.bovis_AF2122/97           --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4581|M.marinum_M               --------------------------------------------------
MUL_4442|M.ulcerans_Agy99           --------------------------------------------------
TH_3893|M.thermoresistible__bu      --------------------------------------------------
Mflv_0296|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0600|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_0398|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4665c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2549|M.avium_104                --------------------------------------------------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
                                                                                      

Mb0950c|M.bovis_AF2122/97           ---MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSEL
Rv0927c|M.tuberculosis_H37Rv        ---MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSEL
MMAR_4581|M.marinum_M               ---MILDRFRLDDQVAVITGGGRGLGAAIALAFAEAGADVVIASRTQSQL
MUL_4442|M.ulcerans_Agy99           ---MILDRFRLDDQVAVITGGGRGFGAAIALAFAEAGADVVIASRTQSQL
TH_3893|M.thermoresistible__bu      ------MDFDLNGKRALVTGSSSGIGAGIVETLAAEGVSVVVHGRNAERA
Mflv_0296|M.gilvum_PYR-GCK          ------MDMGLSGKRALVTGSSSGLGRAIAESLAAEGASVVVHGRDEVRT
MSMEG_0600|M.smegmatis_MC2_155      ------MNIDLTGKTALVTGSTQGIGLAIAETLARSGARVAINGRTASRV
Mvan_0398|M.vanbaalenii_PYR-1       ------MKIDLTGKTALVTGSTQGIGLAIARSLAASGARVAVNGRSRDRV
MAB_4665c|M.abscessus_ATCC_199      -----------------------------MRQLAASGARAVVNGRSQERV
MAV_2549|M.avium_104                ------MHYGIDGRSALVVGGSKGIGFEVAKLLAAEGARVAILARTKTDV
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
                                                                    .*  *. .          

Mb0950c|M.bovis_AF2122/97           DAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLDIVVNNVGG
Rv0927c|M.tuberculosis_H37Rv        DAVAEQIRAAGRRAHTVAADLAHPEVTAQLAGQAVGAFGKLDIVVNNVGG
MMAR_4581|M.marinum_M               DEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFGRLDIVVNNVGG
MUL_4442|M.ulcerans_Agy99           DEVADTVRSIGRRAHVVAADLAHPEATAELAGQAVEAFGRLDIVVNNVGG
TH_3893|M.thermoresistible__bu      EAVADRIRADGGTAATAVGDLATEDGAAQVADTAAAAFSGIDILVNNAGG
Mflv_0296|M.gilvum_PYR-GCK          GAVADGIRARGGDAWAAVGDLATEGGAGAVAAAAG----EVDILVNNAGV
MSMEG_0600|M.smegmatis_MC2_155      DETVAQLG--DLDVVGVAADVATQKGTEALLEQLP----SVDILVNNLGI
Mvan_0398|M.vanbaalenii_PYR-1       DEAVATL---DGDVVGVAADVADAAGAQALAAELP----HIDILVNNLGI
MAB_4665c|M.abscessus_ATCC_199      DAAVAEVGLQHGSVSGVAADVSTADGVERLLKQLP----EVDILINNLGI
MAV_2549|M.avium_104                DAAVEAIRTEGGTAIGVTADVADDGQLTDAVREIAARHGAPLIVVGQAKY
MLBr_02565|M.leprae_Br4923          ALDETANRVGGTTLSLDVTADDAVDKITEHLHDYQG--GHADILVNNAGI
                                                     .                        *::.:   

Mb0950c|M.bovis_AF2122/97           TMP---NTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVIN
Rv0927c|M.tuberculosis_H37Rv        TMP---NTLLSTSTKDLADAFAFNVGTAHALTVAAVPLMLEHSGGGSVIN
MMAR_4581|M.marinum_M               TMP---NTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGSIIN
MUL_4442|M.ulcerans_Agy99           TMP---NTLLTTSTKDLKDAFTFNVATAHALTVAAVPLMLEHSGGGGIIN
TH_3893|M.thermoresistible__bu      SSETGIQSWFALPVSEWGVTYQRNVMSAGYLIHALVPAMKES-GWGRIIQ
Mflv_0296|M.gilvum_PYR-GCK          YDG---LAWSDLAPRQWQSIYEVNVVSGVRMIEYLVPGMRQR-GWGRIIQ
MSMEG_0600|M.smegmatis_MC2_155      FGA---EPAREITDEQWRKYFDVNVLAAVRLIRSYLPGMIEK-GWGRAIQ
Mvan_0398|M.vanbaalenii_PYR-1       FGA---VPAREITDDQWRSYFEVNVLAAARLIRHYLPGMVDR-GWGRVLQ
MAB_4665c|M.abscessus_ATCC_199      FGA---TPAREITDEQWRNYFEVNVLSAVRLIRAYLPAMIGA-GWGRIIQ
MAV_2549|M.avium_104                QRPG--DFADITDVNVYRESFELHTMSQILLLHAVLPAMQDA-GWGRFVH
MLBr_02565|M.leprae_Br4923          TRD---KLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSIS-KGGRVIV
                                                           :  :   :    :         *  : 

Mb0950c|M.bovis_AF2122/97           ISSTMGRLAARGFAAYGT--AKAALAHYTRLAALDLCPR-VRVNAIAPGS
Rv0927c|M.tuberculosis_H37Rv        ISSTMGRLAARGFAAYGT--AKAALAHYTRLAALDLCPR-VRVNAIAPGS
MMAR_4581|M.marinum_M               ITSTMGRVAGRGFAAYGT--AKAALAHYTRLAALDLCPR-IRVNAIAPGS
MUL_4442|M.ulcerans_Agy99           ITSTMGRVAGRGFAAYGT--AKVALAHYTRLAALDLCPR-IRVNAIAPGS
TH_3893|M.thermoresistible__bu      IASAAGIIPTSGQPDYGP--SKAAMINMSMGLSKALAGTGITVNTVMPGM
Mflv_0296|M.gilvum_PYR-GCK          IGGGLALQPAADQPHYNA--TLAARHNLTVSLARELAGTGVTSNTVAPGA
MSMEG_0600|M.smegmatis_MC2_155      IASDSAIVIPEEMIHYGV--SKTALLAVSRGFAKDAAGTGVTVNSVIAGP
Mvan_0398|M.vanbaalenii_PYR-1       IASDSAIVIPEEMIHYGV--SKTALLALSRGFAKDASGTGVTVNSVIAGP
MAB_4665c|M.abscessus_ATCC_199      IASDSAIVIPQEMIHYGV--SKTALLGVTRGFAKDAAGSGVTINSVIAGP
MAV_2549|M.avium_104                IGSATAKEPAGNIHHAVANTSRPSTIGLLKTVSDEYAQFGITVNTVAPGW
MLBr_02565|M.leprae_Br4923          LSSMAGIAGNRGQTNYAT--AKAGVIGLTQALAPGLAEKGITINAVAPGF
                                    : .  .              :  .        :   .   :  *:: .* 

Mb0950c|M.bovis_AF2122/97           ILTSALEVVAAN------------DELRAPMEQATPLR----RLGDPVDI
Rv0927c|M.tuberculosis_H37Rv        ILTSALEVVAAN------------DELRAPMEQATPLR----RLGDPVDI
MMAR_4581|M.marinum_M               ILTSALEVVAAN------------DELRAPMEQATPLR----RLGDPVDI
MUL_4442|M.ulcerans_Agy99           ILTSALEVVAAN------------DELRAPMEQATPLR----RLGDPVDI
TH_3893|M.thermoresistible__bu      IMTEGLRDFLRTFADHRGWG---DDLDKAADYILKGTGQTVHRIGQVSDV
Mflv_0296|M.gilvum_PYR-GCK          ILTEPVREMTYRVAAQRGWGPTWEDVEKAAATTWFPN--DIGRFGRPEEV
MSMEG_0600|M.smegmatis_MC2_155      THTAGVEDFVYQLVDK---SLPWDEAQREFMRKHRPQS-LLQRLIEPEEI
Mvan_0398|M.vanbaalenii_PYR-1       THTAGVEDFVYQLVDK---SLPWEQAQREFMRLHRPQS-LIERLIEPEEI
MAB_4665c|M.abscessus_ATCC_199      THTAGVEDFVYQLVDK---SLPWDEAQREFMKRHRPQS-LVQRLIEPAEI
MAV_2549|M.avium_104                IETENALAYLEQHLGAS-----TDQERREFMLREARVP--AARMGKPSEI
MLBr_02565|M.leprae_Br4923          IETQMTAAIPLAT--------------REVGRRLNSLL----QGGLPVDV
                                      *                        :              :     ::

Mb0950c|M.bovis_AF2122/97           AAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL
Rv0927c|M.tuberculosis_H37Rv        AAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL
MMAR_4581|M.marinum_M               AAAAVYLASPAGSFLTGKTLEVDGGLTHPNLDIPVPDL
MUL_4442|M.ulcerans_Agy99           AAAAVYLASPAGSFLTGKTLEVDGGLTHPNLDIPVPDL
TH_3893|M.thermoresistible__bu      AYAVAFLASPRADFLNGINLHLDGGATQSIY-------
Mflv_0296|M.gilvum_PYR-GCK          AAAVAFLAGVHAGYISGADLRVDGGAIRSVA-------
MSMEG_0600|M.smegmatis_MC2_155      ANMVAYLASPLASATTGGALRVDGGYVDAILP------
Mvan_0398|M.vanbaalenii_PYR-1       ANMVTYLASPLASATTGGALRVDGGYVDAILP------
MAB_4665c|M.abscessus_ATCC_199      ANLVVYLSSPLASATTGAAVRADGGYVDSILP------
MAV_2549|M.avium_104                ASLIAYLCSEPAGYLTGSWIEVDGGLHRSAF-------
MLBr_02565|M.leprae_Br4923          AETIAYFAIPASNAVTGNVIRVCGQAMLGA--------
                                    *   .::.   ..  .*  :.  *