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NRVAVVTGGASGMGEATCHELGRRGHKVAVLDVDVDAAQRVTDHLRSEGVTAFAVGADVTDRAAVEEAFA KVRSELGAVGILVTSAGMFGYASFADITEQSWAQMIDVNLSGTFRCCQVALPDMVDAGWGRIVLISSSSA QRGTPFAAHYAASKGALLTLTKSLAREYAKHGITVNNIPPSGIETPMQHASQAAGYLPPNETIAANIPLG RLGAPADIAAAVGFLCSEEAGFITGQTLGVNGGSVM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0294 | fabG | - | 100% (247) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_0527 | - | 6e-68 | 51.01% (247) | 2-hydroxycyclohexnecarboxyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4800 | - | 4e-58 | 50.42% (240) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 5e-34 | 35.63% (247) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_2469 | - | 1e-104 | 75.61% (246) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 5e-34 | 35.63% (247) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-36 | 37.70% (244) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 1e-32 | 32.64% (242) | 3-oxoacyl- |
| M. marinum M | MMAR_4715 | - | 3e-58 | 50.83% (242) | 3-oxoacyl- |
| M. avium 104 | MAV_3962 | - | 1e-112 | 81.63% (245) | NAD-dependent epimerase/dehydratase:Short-chain |
| M. thermoresistible (build 8) | TH_2435 | - | 7e-68 | 52.50% (240) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 2e-58 | 51.25% (240) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 1e-104 | 75.30% (247) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0294|M.smegmatis_MC2_155 -------------------MNRVAVVTGGASGMGEATCHELGRRGHKVAV
MAV_3962|M.avium_104 --------------------MRVAVVTGGASGMGEATCHELGRRGMKIAV
Mflv_2469|M.gilvum_PYR-GCK ------------------MSSRVAVVTGGASGMGESTCHELGRRGHKVAV
Mvan_4185|M.vanbaalenii_PYR-1 -------------------MTRVAVVTGGASGMGEATCHELGRRGCKVAV
TH_2435|M.thermoresistible__bu -------------------------VTGGASGLGRAIAARLGDDGHRVAV
MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
Mb1519|M.bovis_AF2122/97 MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_2723c|M.abscessus_ATCC_199 MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV
**** *:* : . .* * :*.
MSMEG_0294|M.smegmatis_MC2_155 LDVDVDAAQRVTDHLRSEGVTAFAVGADVTDRAAVEEAFAKVRSELGAVG
MAV_3962|M.avium_104 LDVDEHAAQRVTDDLRTGGATALGVGADVTDRAAVEQAFAKVRSELGPVT
Mflv_2469|M.gilvum_PYR-GCK LDLNGEAAQRVAEELRADGVTALGIAADVTDRAAVEDAFAKVRTELGPVH
Mvan_4185|M.vanbaalenii_PYR-1 LDLDGQAAQRVAEELRGDGVPALGVAADVTDRAAVEDAFAKVRTELGPVH
TH_2435|M.thermoresistible__bu LDIDHAAAEQTAAELRAHGGDAVAVGADVADQDAVHDAFAAIRGSLGPVH
MMAR_4715|M.marinum_M LDLKTPDGE-------------LAFSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99 LDLKTPDGG-------------LAFSADVTNRSQVDAALAAIRQRLGPVT
Mb1519|M.bovis_AF2122/97 THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE
Rv1483|M.tuberculosis_H37Rv THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE
MLBr_01807|M.leprae_Br4923 THRASVVPDW-----------FFGVECDVTDNDAIGAAFKAVEEHQGPVE
MAB_2723c|M.abscessus_ATCC_199 THRGSGAPEG-----------LLGVQCDITDNDQIDAAFKEVEEKQGPVE
. ... .*::: : *: :. *.*
MSMEG_0294|M.smegmatis_MC2_155 ILVTSAGMFGYASFADITEQSWAQMIDVNLSGTFRCCQVALPDMVDAGWG
MAV_3962|M.avium_104 VLVTSAGMFGFSPFLDITAESWSRIIDVNLTGTFHCCQVALPDMVAANWG
Mflv_2469|M.gilvum_PYR-GCK ILVTSAGLVDFAPFLDISPQLWQRLIDVNLNGTFHCAQAAIPDMLAAGWG
Mvan_4185|M.vanbaalenii_PYR-1 ILVTSAGLVDFAPFLEISPDRWQRLIEVNLNGTFHCAQVAIPDMLAAGWG
TH_2435|M.thermoresistible__bu ILVTSAAIAGFTRFDEITLDEWNRYLAVNLTGTFLCVQAALTDMVADGWG
MMAR_4715|M.marinum_M ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MUL_0315|M.ulcerans_Agy99 ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
Mb1519|M.bovis_AF2122/97 VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG
Rv1483|M.tuberculosis_H37Rv VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
MAB_2723c|M.abscessus_ATCC_199 VLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFG
:** *.: : :: : : : : .** *.* : . .* :*
MSMEG_0294|M.smegmatis_MC2_155 RIVLISSSSAQRGTPFAAHYAASKGALLTLTKSLAREYAKHGITVNNIPP
MAV_3962|M.avium_104 RIVMISSSSAQRGSPFAAHYAASKGAVITLTKSLAREYAPHGITVNNIPP
Mflv_2469|M.gilvum_PYR-GCK RIVMISSSSAQRGSPGMAHYAASKGALISLTRSLAREYGAAGITVNNIPP
Mvan_4185|M.vanbaalenii_PYR-1 RIVMISSSSAQRGSPGMAHYAASKGALISFTRSLAREYGPAGITVNNVPP
TH_2435|M.thermoresistible__bu RIVTISSAAGQQGAHRQGHYAATKGGVIALTKTVALDYAAKGITANTVPP
MMAR_4715|M.marinum_M RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
MUL_0315|M.ulcerans_Agy99 RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
Mb1519|M.bovis_AF2122/97 RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP
Rv1483|M.tuberculosis_H37Rv RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP
MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
MAB_2723c|M.abscessus_ATCC_199 RLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAP
* : :.* * :* *:*..: :::::: : . .:*.* :.*
MSMEG_0294|M.smegmatis_MC2_155 SGIETPMQHASQAAGYLPPNETIAANIPLGRLGAPADIAAAVGFLCSEEA
MAV_3962|M.avium_104 SGIETPMQHQGQAAGYLPSNEQIAANIPLGYLGTGADIAAAVGFLTSDEA
Mflv_2469|M.gilvum_PYR-GCK SGIETPMQLQSQAAGFLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSEQA
Mvan_4185|M.vanbaalenii_PYR-1 SGIETPMQHQSQAAGFLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSEEA
TH_2435|M.thermoresistible__bu FVIDSPMLREQQRRGTLPPAEYLTRAIPMGRLGVAEDVAAVCSFLCSDAA
MMAR_4715|M.marinum_M GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA
MUL_0315|M.ulcerans_Agy99 GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA
Mb1519|M.bovis_AF2122/97 GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA
Rv1483|M.tuberculosis_H37Rv GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA
MLBr_01807|M.leprae_Br4923 GFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
MAB_2723c|M.abscessus_ATCC_199 GFIDTDMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVSWLASPDA
*:: * : * :* ::*.. .:* * *
MSMEG_0294|M.smegmatis_MC2_155 GFITGQTLGVNGGSVM------
MAV_3962|M.avium_104 RYITGQVLGVNGGAVMLTVRIR
Mflv_2469|M.gilvum_PYR-GCK GFITGQTLGVNGGSVMA-----
Mvan_4185|M.vanbaalenii_PYR-1 GFITGQTLGVNGGSVMA-----
TH_2435|M.thermoresistible__bu GYLTGQVIGVNGGAIR------
MMAR_4715|M.marinum_M GYITGQILGVNGGRNT------
MUL_0315|M.ulcerans_Agy99 GYITGQILGVNGGRNT------
Mb1519|M.bovis_AF2122/97 SYISGAVIPVDGGMGMGH----
Rv1483|M.tuberculosis_H37Rv SYISGAVIPVDGGMGMGH----
MLBr_01807|M.leprae_Br4923 GYISGAVIPVDGGLGMGH----
MAB_2723c|M.abscessus_ATCC_199 AYVSGAVIPVDGGLGMGH----
:::* : *:**