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VSDDMSDTDEIPVAHRTHVEHKPRLARTIRVLALPIVLGWLVLAVGVNVFVPQLEKVAEEVSVPLSPSDA PSVTGMKHIGEKFKEYDSDNLVLVTLVGDKPLGEDAHRFYDGLVEKLKQDPHVEHALNFWGQRFTSSGVE SYDHRSAYVQVNLRGDQGGAVGDKSVAAIRKIVADSKPPAGVKAYVAGQGALTADTIVVGDASLAKMTII TIIIIAIMLMFVYRSIGTVLLTMVILFVGLATGRGVVALLGETGIMGLSTFAVNLLTALAIAAGTDYAIF MVGRYQEGRERGLDREAAYYDTFAGVTKVVLGSGLTIVGALACLKFTRLPYFSSLAFPCAVGLLVVVAAG VTLTPALIALASGFGLFDPKRKFNYTRWRRLATAIVRWPAPILATSVILAIVGAIGLMGFTPRYNDLYYL PQSASSVQAYNAADRHFTQARLNPDLLMIESDHDLRNPRDMLVLDKVAGAIFRVPGIERVQSITRPLGPP IQDGSVPFQLSVQSAPIRSNLDYLKARVGDIKKITGFLDTQIALLERQYAVTQKLANAADDSSKTTGETA AITDQIRDHIADFDDFWRPIRSYFYWEKHCYDIPICWSLRSLFDALDGFDQLAEKFHALTSDLTDTAKAT RELLAIIPENIAVSKSIRDTTLTIYSSFDSLIAQFDRLTDTNAVMGKSFNDSQVESLFYLPPEIFQNPDF QLGLSLMVSPDGKAARFIITHATDPATVKGIASVDQERQAAKEALKLTSLENADIYLGGTAATFYDIANG AKYDLMIAAVASIVLIFIIMVIVTRALVAAGVIVGTIVLSLGAAFGFSTLIWQHLADFQLHWVATEFALI VLLAVGSDYNLMLVSRIEEEIGAGLKTGLIRGMGVTGPVVTAAGVVFAVTMGAMITSDLRAIGQFGTTIG IGLLFDTFVVRSLITPSIMTAMGRWFWWPKRVRVRPASQMLRSVGPRPLVRALLHQPRHAVPPPPTT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0084 | - | - | 100% (977) | putative transport protein MmpL4 |
| M. avium 104 | MAV_1755 | - | 0.0 | 56.73% (943) | MmpL4 protein |
| M. avium 104 | MAV_3249 | - | 0.0 | 53.11% (932) | Mmp14A protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1583 | mmpL6 | 0.0 | 54.38% (947) | transmembrane transport protein MmpL6 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 52.02% (942) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 54.26% (927) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 51.70% (942) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_2303 | - | 0.0 | 51.86% (966) | putative membrane protein, MmpL |
| M. marinum M | MMAR_3744 | mmpL4_1 | 0.0 | 55.22% (938) | transmembrane transport protein MmpL4_1 |
| M. smegmatis MC2 155 | MSMEG_0382 | - | 0.0 | 52.02% (967) | putative transport protein |
| M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 50.58% (955) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 54.90% (938) | transmembrane transport protein MmpL4_1 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 51.43% (941) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0382|M.smegmatis_MC2_155 ---------MSTEQS-------------GTEKARRPFFARAVRTLSPFII
TH_3056|M.thermoresistible__bu ---------MSVLDR-------------VGVEPRRPRVASFIRRYSVLII
Mflv_3435|M.gilvum_PYR-GCK -----MSAPVSDARTD---------EFPAAHGPHRSFIPRMIRLFAVPII
Mvan_3189|M.vanbaalenii_PYR-1 -----MSAPVSDARTD---------EFPAARQPHRPFIPRMIRLFAVPII
Rv0450c|M.tuberculosis_H37Rv ---------MSTKFAN---------DSNTNARPEKPFIARMIHAFAVPII
MLBr_02378|M.leprae_Br4923 ---------MTVKCAN---------DLDTHTKP--PFVARMIHRFAVPII
Mb1583|M.bovis_AF2122/97 ---------MSNHHR------------------PRPWLPHTIRRLSLPIL
MMAR_3744|M.marinum_M MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPII
MUL_3688|M.ulcerans_Agy99 MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPII
MAB_2303|M.abscessus_ATCC_1997 ---------MSTHSAP-----------THGAAQKPSRIARFIHTFSVPII
MAV_0084|M.avium_104 -----MSDDMSDTDEIP--------VAHRTHVEHKPRLARTIRVLALPIV
:: . .. :: : *:
MSMEG_0382|M.smegmatis_MC2_155 VGWLAVILVTTLAAVGGDWSAAIPALERVGEKNSVSLMPQDAPSAKAMKH
TH_3056|M.thermoresistible__bu LGWVALTVLAT---------VAVPPLEAVEREKSLSLIPYDAPAFAAMHR
Mflv_3435|M.gilvum_PYR-GCK LGWIALIVVVN---------VTVPQLETVGEAQAVSMSPNDAPSMISMKK
Mvan_3189|M.vanbaalenii_PYR-1 LGWIALIVILN---------VTVPQLEAVGEARAVSMSPNEAPSLISMKK
Rv0450c|M.tuberculosis_H37Rv LGWLAVCVVVT---------VFVPSLEAVGQERSVSLSPKDAPSFEAMGR
MLBr_02378|M.leprae_Br4923 LVWLAIAVTVS---------VFIPSLEDVGQERSVSLSPKDAPSYIAMQK
Mb1583|M.bovis_AF2122/97 LFWVGVAAITN---------AAVPQLEVVGEAHNVAQSSPDDPSLQAMKR
MMAR_3744|M.marinum_M LGWVLLTVLVN---------VVVPSLEVVSEQHSAPMTPMDAPSMKAMMR
MUL_3688|M.ulcerans_Agy99 LGWVLLTVLVN---------VVVPSLEVVSEQHSAPMTPMDAPSMKAMMR
MAB_2303|M.abscessus_ATCC_1997 LAWLVLTVIVN---------VVVPQLEEVGKEHSVSLASKDAPSYQAIKR
MAV_0084|M.avium_104 LGWLVLAVGVN---------VFVPQLEKVAEEVSVPLSPSDAPSVTGMKH
: *: : . . :* ** * . . . : *: .: :
MSMEG_0382|M.smegmatis_MC2_155 MGQKFEESDSDSFAMIVLEGQEPLG----PDALDYYTGLISELRNDSKHV
TH_3056|M.thermoresistible__bu MGELFDEPDSESIAIIVLEGQEPLG----LEAHEYYDQLISQLREHPQYV
Mflv_3435|M.gilvum_PYR-GCK VGELFEEGDSDSSVMIVFEGDQPLG----DEAHAWYDELVDRLEADTAHV
Mvan_3189|M.vanbaalenii_PYR-1 VGELFREGDSDSSVMIVFEGDQPLG----DEAHAWYDELVERLRADTKHV
Rv0450c|M.tuberculosis_H37Rv IGMVFKEGDSDSFAMVIIEGNQPLG----DAAHKYYDGLVAQLRADKKHV
MLBr_02378|M.leprae_Br4923 MGQVFNEGNSDSVIMIVLEGDKPLG----DDAHRFYDGLIRKLRADK-HV
Mb1583|M.bovis_AF2122/97 IGKVFHEFDSDSAAMIVLEGDKPLG----NDAHRFYDTLLRNLSNDTKHV
MMAR_3744|M.marinum_M LGHNFREFDSNSTVMIVLEGQHKLG----DDAHQYYDSLIRQLRQDPEHI
MUL_3688|M.ulcerans_Agy99 LGHNFREFDSNSTVMIVLEGQHKLG----DDAHQYYDSLIRQLRQDPEHI
MAB_2303|M.abscessus_ATCC_1997 QGELFQQFKDDSMVMVLLENDTKFSTDMNDKAHTFYRELVKRLRADTKHV
MAV_0084|M.avium_104 IGEKFKEYDSDNLVLVTLVGDKPLG----EDAHRFYDGLVEKLKQDP-HV
* * : ..:. :: : .: :. * :* *: .* . ::
MSMEG_0382|M.smegmatis_MC2_155 EHVQDLWGDRLTASSAQSADGKAAYVQLNLAGNQGTPLGDESVAAVRDLV
TH_3056|M.thermoresistible__bu QHIRDFWGDPLTAGAAQSDDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIV
Mflv_3435|M.gilvum_PYR-GCK QSVQDFWSDPLTASGSQSNDGKAAYVQVKLSGNQGEALANESVKAVQQTV
Mvan_3189|M.vanbaalenii_PYR-1 QSVQDFWSDPLTASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIV
Rv0450c|M.tuberculosis_H37Rv QSVQDLWGDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIV
MLBr_02378|M.leprae_Br4923 QSVQDFWGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIV
Mb1583|M.bovis_AF2122/97 EHVQDFWGDPLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIV
MMAR_3744|M.marinum_M QHIQDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVI
MUL_3688|M.ulcerans_Agy99 QHIQDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVI
MAB_2303|M.abscessus_ATCC_1997 EYAQDFWGDRITAGGAQSVDEKAAYVQLNLRGDQGTTEGKESVTAVQDNV
MAV_0084|M.avium_104 EHALNFWGQRFTSSGVESYDHRSAYVQVNLRGDQGGAVGDKSVAAIRKIV
: ::*.: :*: . :* * ::*:* : * * * ::: * :. :
MSMEG_0382|M.smegmatis_MC2_155 ARTPA--------PEGVSVYVTGAAPLVSDMQHSGNRSILKITAVTVVII
TH_3056|M.thermoresistible__bu ERTPA--------PEGVETFVTGPAALGADAGDSGTATVILITLVTVAVI
Mflv_3435|M.gilvum_PYR-GCK SSLEP--------PPGVRAFVTGPAALAADQHIAGDRSMRLIEAATFTVI
Mvan_3189|M.vanbaalenii_PYR-1 RSLEP--------PPGVRAFVTGPAALAADQHIASDRSVRVIELVTFAVI
Rv0450c|M.tuberculosis_H37Rv ESTPA--------PPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVI
MLBr_02378|M.leprae_Br4923 VQTPA--------PPGITAWVTGASALIADMHHSGDKSMIRITATSVIVI
Mb1583|M.bovis_AF2122/97 AHTPP--------PAGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVI
MMAR_3744|M.marinum_M NRTHE--------PAGVKAYVTGPAALSDDMHLIGNASLAKITMFTLGAI
MUL_3688|M.ulcerans_Agy99 NRTHE--------PAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAI
MAB_2303|M.abscessus_ATCC_1997 AKLIDESKKNGTYPDGLKVFVTGQAALTMDMNDAGDKSMLKMTGITFIVI
MAV_0084|M.avium_104 ADSKP--------PAGVKAYVAGQGALTADTIVVGDASLAKMTIITIIII
* *: .:*:* ..* * . : :. *
MSMEG_0382|M.smegmatis_MC2_155 FAMLLMVYRSVITVILLLIMVGFEVAAARGIVAFLGANEVFVLSTFAVNM
TH_3056|M.thermoresistible__bu FLMLLFFFRSFLTVIVLLLTVAVELQVARGLVAYLGLQGWVGLTTYVVNL
Mflv_3435|M.gilvum_PYR-GCK IVMLLLVYRSIVTVLITLVMVVMSLATARGVVAFLGHHEIIGLSTFATNL
Mvan_3189|M.vanbaalenii_PYR-1 IVMLLLVYRSIVTVLLTLVMVVLSLATARGVVAFLGWHEIIGLSLFATNL
Rv0450c|M.tuberculosis_H37Rv FIMLLLVYRSIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSL
MLBr_02378|M.leprae_Br4923 LVTLLLVYRSFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNL
Mb1583|M.bovis_AF2122/97 AVMLLFVYRSVVTMVLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNL
MMAR_3744|M.marinum_M AVMLLLVYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANI
MUL_3688|M.ulcerans_Agy99 AVMLLLVYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANI
MAB_2303|M.abscessus_ATCC_1997 TIMLLFIYRSITTVLLILFMVFVELGAARGVVAILGNAEIIGLSTFAVNL
MAV_0084|M.avium_104 AIMLMFVYRSIGTVLLTMVILFVGLATGRGVVALLGETGIMGLSTFAVNL
*::.:**. * :: :. . .**:** ** . *: : ..:
MSMEG_0382|M.smegmatis_MC2_155 LVFLAIAAGTDYGIFFFGRYQEARAAGEDRETAYYSMYRGVTPVVMASGL
TH_3056|M.thermoresistible__bu LVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSAYFTTYRSVAKVVLASGL
Mflv_3435|M.gilvum_PYR-GCK LVTLAIAAATDYAIFLIGRYQEARTAGEDKETAYYTMFHGTAHVVLGSGL
Mvan_3189|M.vanbaalenii_PYR-1 LVTLAIAAATDYAIFLIGRYQEARTNGEDKESAYYTMFHGTAHVVLGSGL
Rv0450c|M.tuberculosis_H37Rv LTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGL
MLBr_02378|M.leprae_Br4923 LTSLAIAAGTDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGL
Mb1583|M.bovis_AF2122/97 LTLLVIAAGTDYAIFVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGL
MMAR_3744|M.marinum_M LTMLAIAAGTDYGIFLVGRYQEARQAGEDREDAYYTTFRGVAPVVLGSGL
MUL_3688|M.ulcerans_Agy99 LTMLAIAAGTDYGIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGL
MAB_2303|M.abscessus_ATCC_1997 LTSLAIAAGTDYAIFLIGRYQELRAEGKERLESFYLTYHSVSHVILGSGL
MAV_0084|M.avium_104 LTALAIAAGTDYAIFMVGRYQEGRERGLDREAAYYDTFAGVTKVVLGSGL
*. : ***.***.**. ***:* * :: ::: : .. *::.***
MSMEG_0382|M.smegmatis_MC2_155 TIAGAIFCLTFTRLPYFHTMGVPCAIGMLAAVAVAVTLVPAGVALAGRIG
TH_3056|M.thermoresistible__bu TIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVAVALTLVPATIALGSRFG
Mflv_3435|M.gilvum_PYR-GCK TIAGATFCLSFTRLPYFQTMGVPLAIGMFVVVMAGVVLMVACISVATRFG
Mvan_3189|M.vanbaalenii_PYR-1 TIAGATYCLSFTRLPYFQTLGVPLAIGMFVVVMAGVILMVAMISVATRFG
Rv0450c|M.tuberculosis_H37Rv TIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG
MLBr_02378|M.leprae_Br4923 TISGATFCLSFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG
Mb1583|M.bovis_AF2122/97 TVAGAVYCLSFTRLPYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFG
MMAR_3744|M.marinum_M TIAGATYCLSFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH
MUL_3688|M.ulcerans_Agy99 TIAGATYCLSFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH
MAB_2303|M.abscessus_ATCC_1997 TIAGATFCLKFTRLPYFESLGVPCAIGMLVVVAASLTIGPAVLLVATKFG
MAV_0084|M.avium_104 TIVGALACLKFTRLPYFSSLAFPCAVGLLVVVAAGVTLTPALIALASGFG
*: ** **.*:*:* * .:. * ::*:: .: ..: : : : :. :
MSMEG_0382|M.smegmatis_MC2_155 -WLEPKRKMRVRRWRGIGTAIVRWPAPILVASLAVALVGLLALPGYETSY
TH_3056|M.thermoresistible__bu -LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAVALSLVGLLTLPGYNPSY
Mflv_3435|M.gilvum_PYR-GCK KLLEPKRAMRIRGWRKIGAAIVRWPGPILVATMAITLVGLLALPGYKTNY
Mvan_3189|M.vanbaalenii_PYR-1 KLLEPKRAMRIRGWRKIGAAVVRWPGPILVATLAITLVGLLALPGYKTNY
Rv0450c|M.tuberculosis_H37Rv -LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSY
MLBr_02378|M.leprae_Br4923 -LFEPKRLIKVRGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNY
Mb1583|M.bovis_AF2122/97 -CFEPKRRMRTRGWRRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSY
MMAR_3744|M.marinum_M LFESKRAANRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSY
MUL_3688|M.ulcerans_Agy99 PFESKRAANRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSY
MAB_2303|M.abscessus_ATCC_1997 -LLESKRTIKNRTWRKVGTAIVRWPGPILAVTMIIALLGLGILPSYTVNY
MAV_0084|M.avium_104 -LFDPKRKFNYTRWRRLATAIVRWPAPILATSVILAIVGAIGLMGFTPRY
. : ** :.:.:**** *:* : : ::* * .: *
MSMEG_0382|M.smegmatis_MC2_155 NDRDYIPADIPANAGFAAADRHFSQARMT-PDILMVESDHDMRNPTDFLV
TH_3056|M.thermoresistible__bu SDQEFIPDDIPASEGYKAAARHFPASAMSVPDVVLIEADRDMRNPADLLV
Mflv_3435|M.gilvum_PYR-GCK NDRDYLPADLPANQGYAVADEHFDQARMN-PELLMIESDHDLRNSADFLV
Mvan_3189|M.vanbaalenii_PYR-1 NDRTYLPADLPANEGYAVADRHFDQARMN-PELLMIESDHDLRNSADFLV
Rv0450c|M.tuberculosis_H37Rv NDRDYLPDFIPANQGYAAADRHFSQARMK-PEILMIESDHDMRNPADFLV
MLBr_02378|M.leprae_Br4923 KDRAYLPASIPANQGFAAADRHFPQARMK-PEILMIESDHDMRNPADFLI
Mb1583|M.bovis_AF2122/97 DARYYMPATAPANIGYMAAERHFPQARLN-PELLMIETDHDMRNPADMLI
MMAR_3744|M.marinum_M NDRYYLPASAPSNLGEAAADRHFSHARMN-PDMLMVEAEHDMRNPADMLV
MUL_3688|M.ulcerans_Agy99 NDRYYLPASAPSNLGEAAADRHFSHARMN-PDMLMVEAEHDMRNPADMLV
MAB_2303|M.abscessus_ATCC_1997 NDRYYIPASLPSIQGFQASDRHFSKARMN-PDILIVEADKDLRTPANMLV
MAV_0084|M.avium_104 NDLYYLPQSASSVQAYNAADRHFTQARLN-PDLLMIESDHDLRNPRDMLV
. ::* .: . .: .** : :. *:::::*:::*:*.. ::*:
MSMEG_0382|M.smegmatis_MC2_155 LNKIAKAIFKVRGVSRVQGITRPEGTPIERTSIPFLLSLQSAGQVQATNF
TH_3056|M.thermoresistible__bu LNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTIPFMLSMSQASQRLALPF
Mflv_3435|M.gilvum_PYR-GCK IDKIAKALFRVEGIARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKY
Mvan_3189|M.vanbaalenii_PYR-1 IDKIAKAIFKVEGIARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKY
Rv0450c|M.tuberculosis_H37Rv LDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKY
MLBr_02378|M.leprae_Br4923 LDKLARGIFRVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKY
Mb1583|M.bovis_AF2122/97 LDRIAKAVFHLPGIGLVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKY
MMAR_3744|M.marinum_M LDKVAKNVIRTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAF
MUL_3688|M.ulcerans_Agy99 LDKVAKNVIRTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAF
MAB_2303|M.abscessus_ATCC_1997 LDRIAKNVFRVEGINKVQSMTRPMGAPIDHSSVPFQVSMQSVSMTENMNY
MAV_0084|M.avium_104 LDKVAGAIFRVPGIERVQSITRPLGPPIQDGSVPFQLSVQSAPIRSNLDY
::::* ::. *: :* :*** * :. ::** *:. :
MSMEG_0382|M.smegmatis_MC2_155 QKQRIGDMLKQVDDMNMMIGVMKTTYGVLQELAATTHSLNG-STHELRDV
TH_3056|M.thermoresistible__bu QRARMDDMLKQADELTETIALMRRMQSLMEKMVATTHSMVG-TTHELLDT
Mflv_3435|M.gilvum_PYR-GCK MQDRMADMLVQADEMANTIKTMEKMSGLTAQMADITHSMVT-KMEGMVVD
Mvan_3189|M.vanbaalenii_PYR-1 MQDRMADMLVQADEMANTIATMEKMSNLTAQMADITHSMVS-KMENMLTD
Rv0450c|M.tuberculosis_H37Rv QRDRANDMLKQADEMATTIAVLTRMHSLMAEMASTTHRMVG-DTEEMKEI
MLBr_02378|M.leprae_Br4923 QKDRMNDLLRQAENMAETIASMRRMHQLMALLTENTHHILN-DTVEMQKT
Mb1583|M.bovis_AF2122/97 QRDRAADLLKQAEELGKTIEILQRQYALQQELAAATHEQAE-SFHQTIAT
MMAR_3744|M.marinum_M LKERMADMTKMADEMQVLIDTTERMYAVMRDLDTTTTDMAR-VTAETSTI
MUL_3688|M.ulcerans_Agy99 LKERMADMTKMADEMQVLIDTTERMYAVMRELDTTTTDMAR-VTAETSTI
MAB_2303|M.abscessus_ATCC_1997 LKNSMSDMLKMTDDMGSMIAIMERMYSLMKELTGVTHHMATVTTPDMIHV
MAV_0084|M.avium_104 LKARVGDIKKITGFLDTQIALLERQYAVTQKLANAADDSSK-TTGETAAI
: *: . : * : : :
MSMEG_0382|M.smegmatis_MC2_155 ARDLRGSIAIFDDLLRPIRNYFYWEPHCYNIPICWSLRSIFDAMDGVDRL
TH_3056|M.thermoresistible__bu TRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPICWSIRSIFDALDGINEM
Mflv_3435|M.gilvum_PYR-GCK IEDLRDSIANFDDFFRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINIM
Mvan_3189|M.vanbaalenii_PYR-1 IEDLRDSIANFDDFFRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINVM
Rv0450c|M.tuberculosis_H37Rv TEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKL
MLBr_02378|M.leprae_Br4923 TSKLRDEIANFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQI
Mb1583|M.bovis_AF2122/97 VKELRDRIANFDDFFRPIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQL
MMAR_3744|M.marinum_M TDELRDHLAEFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKL
MUL_3688|M.ulcerans_Agy99 TDELRDHLAEFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKL
MAB_2303|M.abscessus_ATCC_1997 ADEMRDNMANFDDFYRPLRNYLYWEKHCFDIPMCWSMRSLFDALDGIDKL
MAV_0084|M.avium_104 TDQIRDHIADFDDFWRPIRSYFYWEKHCYDIPICWSLRSLFDALDGFDQL
.:*. :* ***: **:*.*::** **:.:* **::**:**::**.: :
MSMEG_0382|M.smegmatis_MC2_155 NDELQVLVDNMDRLDALVPELVAQFPEYIASMETFRELTLTSYSTFSGLL
TH_3056|M.thermoresistible__bu TEKMEELVEDMDRLDALMPQMLVQFPQMIETMESSRTMILTMHATMSGIF
Mflv_3435|M.gilvum_PYR-GCK TDDFKAIIPDMKRLDTLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQ
Mvan_3189|M.vanbaalenii_PYR-1 TDDFREILPDMKRLDSLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQ
Rv0450c|M.tuberculosis_H37Rv SEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIF
MLBr_02378|M.leprae_Br4923 DERLNSIVGDIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIF
Mb1583|M.bovis_AF2122/97 GEQLASVTVTLDKLAAIQPQLVALLPDEIASQQINRELALANYATMSGIY
MMAR_3744|M.marinum_M SEKFSELTEDIQHTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAML
MUL_3688|M.ulcerans_Agy99 SEKFSELTEDIQRTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAML
MAB_2303|M.abscessus_ATCC_1997 TESMRGLLDDVTNMDKLMPQVVEQLPPMIAITKNMRNTMLTMYSTMNGMI
MAV_0084|M.avium_104 AEKFHALTSDLTDTAKATRELLAIIPENIAVSKSIRDTTLTIYSSFDSLI
: : : : ::: :* * : : *: : .
MSMEG_0382|M.smegmatis_MC2_155 QQMDEQTEDVTAMGQAFDAAKNDDTFFLPPEVFDNPDFKRAMTSFLSPDG
TH_3056|M.thermoresistible__bu DQMESSSENATAMGKAFDASHNDDSFYLPPEALENKDFQRVMEIFLSPDG
Mflv_3435|M.gilvum_PYR-GCK DQMAAMSEDADAMGEAFDDSMNDDSFYLPPEIFENADFQRGLEQFLSPDG
Mvan_3189|M.vanbaalenii_PYR-1 DQMAAMSEDADAMGEAFDDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDG
Rv0450c|M.tuberculosis_H37Rv DQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDG
MLBr_02378|M.leprae_Br4923 DQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDG
Mb1583|M.bovis_AF2122/97 AQTAALIENAAAMGQAFDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADG
MMAR_3744|M.marinum_M DQMDELSNTAIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDG
MUL_3688|M.ulcerans_Agy99 DQMDELSNTAIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDG
MAB_2303|M.abscessus_ATCC_1997 GQMDRMTDTATVMGQAFDEAKNDDFFYLPPEAFDNEDFKKGVKLMMSPDG
MAV_0084|M.avium_104 AQFDRLTDTNAVMGKSFNDSQVESLFYLPPEIFQNPDFQLGLSLMVSPDG
* : .**::*: : :. *:**** :.* **: : ::*.**
MSMEG_0382|M.smegmatis_MC2_155 KAARFIISHNGDPATPEGISRVDQMQTAAVEALKGTPLTDAQVYLAGTAP
TH_3056|M.thermoresistible__bu KAARMLVTQRGDPATPEGMALVEPIYIAAEEALKGTPLESSRIYLAGSAA
Mflv_3435|M.gilvum_PYR-GCK HAVRFIISHEGDPLSPEGVAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAA
Mvan_3189|M.vanbaalenii_PYR-1 HAVRFIISHEGDPLSPEGVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAA
Rv0450c|M.tuberculosis_H37Rv HAARFIILHRGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAA
MLBr_02378|M.leprae_Br4923 HAARFIILHRGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAA
Mb1583|M.bovis_AF2122/97 KAARMIISHEGDPATPEGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAA
MMAR_3744|M.marinum_M KSARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAA
MUL_3688|M.ulcerans_Agy99 KSARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAA
MAB_2303|M.abscessus_ATCC_1997 KAAQFIITHEGDYASNESLANTEVELKAAKEAIKGTPLDESKLYLGGTAP
MAV_0084|M.avium_104 KAARFIITHATDPATVKGIASVDQERQAAKEALKLTSLENADIYLGGTAA
::.:::: : * : .: : ** *.:* :.: : :**.*:*.
MSMEG_0382|M.smegmatis_MC2_155 TAKDWKDGSTYDLLIAGIAAMCLIFIIMLIVTRSFIAALVIVGTVVLSLG
TH_3056|M.thermoresistible__bu GVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRSVIAALVIVGTVVLSLG
Mflv_3435|M.gilvum_PYR-GCK VFKDMQDGNNYDLLIAGIAALGLIFIIMLILTRAVVAAAVIVGTVVLSLA
Mvan_3189|M.vanbaalenii_PYR-1 TFKDMQDGNNYDLLIAGISALGLIFIIMLILTRAIVAAAVIVGTVVLSLA
Rv0450c|M.tuberculosis_H37Rv VFHDISEGAQWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLG
MLBr_02378|M.leprae_Br4923 VFKDIDEGANWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLG
Mb1583|M.bovis_AF2122/97 TFKDIQDGATYDLLIAGIAALSLILLIMMIITRSLVAALVIVGTVALSLG
MMAR_3744|M.marinum_M TFKDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIA
MUL_3688|M.ulcerans_Agy99 TFKDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIA
MAB_2303|M.abscessus_ATCC_1997 TYHDIGEMVKYDLMIAVIASLCLIFVIMLVITRSIVAAFTIVGTIAVSLG
MAV_0084|M.avium_104 TFYDIANGAKYDLMIAAVASIVLIFIIMVIVTRALVAAGVIVGTIVLSLG
* : :**:** :::: **::**:.:**:.:** .**** . *:.
MSMEG_0382|M.smegmatis_MC2_155 ASFGLSVLLWQYILGIHLHWMVLAMSVIILLAVGSDYNLLLVSRIKEEVG
TH_3056|M.thermoresistible__bu ASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIG
Mflv_3435|M.gilvum_PYR-GCK ASFGLSVLFWQHILGQPLHWMVLAMAVIILLAVGADYNLLLVSRLKEEIH
Mvan_3189|M.vanbaalenii_PYR-1 ASFGLSVLFWQHILGTELHWMVLAMAVIVLLAVGADYNLLLVSRLKEEIH
Rv0450c|M.tuberculosis_H37Rv ASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIG
MLBr_02378|M.leprae_Br4923 ASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQ
Mb1583|M.bovis_AF2122/97 ASFGLSVLVWQHLLGIQLYWIVLALAVILLLAVGSDYNLLLISRFKEEIG
MMAR_3744|M.marinum_M ASFGLSVLIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIH
MUL_3688|M.ulcerans_Agy99 ASFGLSVLIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIH
MAB_2303|M.abscessus_ATCC_1997 ASFGLSVLLWEHILGLQLHWFVLPFTVIILLAVGSDYNLLLVSRFKEELH
MAV_0084|M.avium_104 AAFGFSTLIWQHLADFQLHWVATEFALIVLLAVGSDYNLMLVSRIEEEIG
*:**:*.*.*: : :::.. :::*:*****:****:*:**:.:*:
MSMEG_0382|M.smegmatis_MC2_155 AGINTGIVRAMGGTGKVVTSAGLVFAGTMAAMVVSDLRIIGQIGTTIGLG
TH_3056|M.thermoresistible__bu AGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIVSDLLMIGQVGTTIALG
Mflv_3435|M.gilvum_PYR-GCK AGIGTGIIRAMGGSGSVVTAAGLVFALTMMSMSVSELTVIGQVGTTIGLG
Mvan_3189|M.vanbaalenii_PYR-1 AGIGTGIIRAMGGSGSVVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLG
Rv0450c|M.tuberculosis_H37Rv AGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLG
MLBr_02378|M.leprae_Br4923 AGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLG
Mb1583|M.bovis_AF2122/97 AGLNTGIIRAMAGTGGVVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLG
MMAR_3744|M.marinum_M AGLKTGIIRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIG
MUL_3688|M.ulcerans_Agy99 AGLKTGIIRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIG
MAB_2303|M.abscessus_ATCC_1997 GGLNTAILRGVGGSGSVATQAGLVFAFTMGSMITSDLIAIGQSGSAICLG
MAV_0084|M.avium_104 AGLKTGLIRGMGVTGPVVTAAGVVFAVTMGAMITSDLRAIGQFGTTIGIG
.*: *.::*.:. :* *.* **:*** ** :: *:* :** *::: :*
MSMEG_0382|M.smegmatis_MC2_155 LLFDTMIVRSFMTPSIAALLGRWFWWPQKVRPRPASALLEPYGPRPLVRA
TH_3056|M.thermoresistible__bu LLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRPASAMLRPVGPRPLVRS
Mflv_3435|M.gilvum_PYR-GCK LLFDTLVIRAFMTPSIAALLGPWFWWPQRVRTRPVPAPWPRSGGLQSDPS
Mvan_3189|M.vanbaalenii_PYR-1 LLFDTLVIRAFMTPSIAALLGPWFWWPQRVRTRPVPAPWPRPGGLQSDPS
Rv0450c|M.tuberculosis_H37Rv LLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRP
MLBr_02378|M.leprae_Br4923 LLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RS
Mb1583|M.bovis_AF2122/97 LLFDTLVVRAFMTPSIAVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRE
MMAR_3744|M.marinum_M LLLDTLIVRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH----
MUL_3688|M.ulcerans_Agy99 LLLDTLIVRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH----
MAB_2303|M.abscessus_ATCC_1997 LLFDTFIIRAFMTPAIAALMGRWFWWPMKVSKYATDPPPPPVPVESQTPP
MAV_0084|M.avium_104 LLFDTFVVRSLITPSIMTAMGRWFWWPKRVRVRPASQMLRSVGPRPLVRA
**:**:::*::: *:: . :* *****
MSMEG_0382|M.smegmatis_MC2_155 LLEGPSGAASPGGPGGRLSDDDTPTGPMRTR
TH_3056|M.thermoresistible__bu LLLRD--------------------------
Mflv_3435|M.gilvum_PYR-GCK EGVRA--------------------------
Mvan_3189|M.vanbaalenii_PYR-1 EGVKV--------------------------
Rv0450c|M.tuberculosis_H37Rv LAMSSDRLG----------------------
MLBr_02378|M.leprae_Br4923 LVYSD--------------------------
Mb1583|M.bovis_AF2122/97 LLLREGNDDPRTQVATHR-------------
MMAR_3744|M.marinum_M -------------------------------
MUL_3688|M.ulcerans_Agy99 -------------------------------
MAB_2303|M.abscessus_ATCC_1997 PPAPVPVGPSPGPAHDDAVTTEFPRPPV---
MAV_0084|M.avium_104 LLHQPRHAVPPPPTT----------------