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VFIILGWVALTLLVTFGVPRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFAMLVLEGQQQLG DDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQSPDGKAVYVQLNLAGNQGTTLGQESVAAVRDV IARIPPPAGLKAYVTGPAALFSDMQLAGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLLLTVGIEVFA ARGVIAFVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFGRYQEAREAGEDRATAYFTTYRSVAPVVLG SGLTIAGAMLCLSFTRMPIFQTMGLPCSVGMLISVFIALTLVPAVLTVGGGFGLFDPKRAIGFGRWRRIG TAIVRWPAPILTATIAVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAAADRHFTQSRMMPELLMIESD HDMRNPADFLVLHRLAKGVFGVHGISRVQGITRPEGTPIQHTSIPFLLSMQQATMHQDIQYMKARMDDML VQADLMRKQIEIMRHIYELQKRLTDITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRSYFYWEKHCYD IPICWSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQLLEQYPPMIAMSEDMLRMMLTNHSTMSGII GQMDSNNKDATAMGEAFDASKNDDSFYLPPDIFDNADFKKAMSQFLSPDGKAARFIISHRGDPATSEALN RIDKIRSAAEEALKNTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGALCLIFIIMLILTRSFIAALV IVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLPMSVIVLLAVGSDYNLLLVSRMKEEISAGINTGIIRA MGGTGKVVTNAGLVFAFTMASMVVSDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPQLV RRRPASQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRPTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3249 | - | - | 100% (952) | Mmp14A protein |
| M. avium 104 | MAV_3248 | - | 0.0 | 64.27% (932) | Mmp14A protein |
| M. avium 104 | MAV_2510 | - | 0.0 | 60.46% (913) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 65.10% (934) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 59.80% (923) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 65.20% (934) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 63.60% (912) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_4115c | - | 0.0 | 63.77% (955) | putative membrane protein, MmpL |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 65.50% (913) | transmembrane transport protein MmpL5_2 |
| M. smegmatis MC2 155 | MSMEG_0382 | - | 0.0 | 65.43% (940) | putative transport protein |
| M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 59.06% (933) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 58.84% (916) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 60.20% (917) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVF-
Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVF-
MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDT--HTKPPFVARMIHRFAVPIILVWLAIAVTVSVF-
MMAR_0771|M.marinum_M ----MTVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVF-
MAB_4115c|M.abscessus_ATCC_199 ------MKPGMSAETDSARSRPFIARTIRTLSPLIILGWLVLILYTTLAS
MSMEG_0382|M.smegmatis_MC2_155 -------MSTEQSGTEKAR-RPFFARAVRTLSPFIIVGWLAVILVTTLAA
MAV_3249|M.avium_104 --------------------------------MFIILGWVALTLLVTFG-
TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVA-
Mflv_4418|M.gilvum_PYR-GCK ---------------MADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVA-
Mvan_1936|M.vanbaalenii_PYR-1 ---------------MADAGRSGIGRIIHLLAVPIVLGWIALTVLTNVA-
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSV-
::: *: : .
Mb0458c|M.bovis_AF2122/97 --------VPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFA
Rv0450c|M.tuberculosis_H37Rv --------VPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFA
MLBr_02378|M.leprae_Br4923 --------IPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVI
MMAR_0771|M.marinum_M --------IPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQA
MAB_4115c|M.abscessus_ATCC_199 VNWDWTKAIPALETVGDERSVSLMPQDAPAVKAILRMGKDFNESNSDSSA
MSMEG_0382|M.smegmatis_MC2_155 VGGDWSAAIPALERVGEKNSVSLMPQDAPSAKAMKHMGQKFEESDSDSFA
MAV_3249|M.avium_104 --------VPRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFA
TH_3056|M.thermoresistible__bu --------VPPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIA
Mflv_4418|M.gilvum_PYR-GCK --------VPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFDSDSSA
Mvan_1936|M.vanbaalenii_PYR-1 --------VPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFDSDSSA
MUL_0757|M.ulcerans_Agy99 --------VPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAA
:* ** * .:: : . **: :: ::* * * :*:*
Mb0458c|M.bovis_AF2122/97 MVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
Rv0450c|M.tuberculosis_H37Rv MVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
MLBr_02378|M.leprae_Br4923 MIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQS
MMAR_0771|M.marinum_M MIVLEGKDALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQS
MAB_4115c|M.abscessus_ATCC_199 MIVLEGKEPLGDDAHQYYAQLVRELRNDPEHVEHVQDLWGDRLTSSSVQS
MSMEG_0382|M.smegmatis_MC2_155 MIVLEGQEPLGPDALDYYTGLISELRNDSKHVEHVQDLWGDRLTASSAQS
MAV_3249|M.avium_104 MLVLEGQQQLGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQS
TH_3056|M.thermoresistible__bu IIVLEGQEPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQS
Mflv_4418|M.gilvum_PYR-GCK MVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQS
Mvan_1936|M.vanbaalenii_PYR-1 MVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPLTASGAQS
MUL_0757|M.ulcerans_Agy99 MIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQS
::::**.. ** * :* :: :*. . *: : *:*** ** ..**
Mb0458c|M.bovis_AF2122/97 NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP--APPGIKAYVTGP
Rv0450c|M.tuberculosis_H37Rv NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP--APPGIKAYVTGP
MLBr_02378|M.leprae_Br4923 NDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP--APPGITAWVTGA
MMAR_0771|M.marinum_M NDGKAAYVQLNLAGNQGEPLANESVEAVRKIVKETP--APPGVTTYVTGA
MAB_4115c|M.abscessus_ATCC_199 PDEKAAYVQLNLVGNQGTAQGDQSVAAVRDIVKRTSPSAPKDVETYVAGA
MSMEG_0382|M.smegmatis_MC2_155 ADGKAAYVQLNLAGNQGTPLGDESVAAVRDLVARTP--APEGVSVYVTGA
MAV_3249|M.avium_104 PDGKAVYVQLNLAGNQGTTLGQESVAAVRDVIARIP--PPAGLKAYVTGP
TH_3056|M.thermoresistible__bu DDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIVERTP--APEGVETFVTGP
Mflv_4418|M.gilvum_PYR-GCK TDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP--APPGIKAYVTGG
Mvan_1936|M.vanbaalenii_PYR-1 TDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP--APPGLKAYVTGG
MUL_0757|M.ulcerans_Agy99 GDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ--APPGVKVYVTGS
* **.:**: * *. * :::: **: :: .* .: .:*:*
Mb0458c|M.bovis_AF2122/97 SALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVE
Rv0450c|M.tuberculosis_H37Rv SALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVE
MLBr_02378|M.leprae_Br4923 SALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIE
MMAR_0771|M.marinum_M AALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVE
MAB_4115c|M.abscessus_ATCC_199 APLASDMQHAGNKSILKITAVTVVIIFTLLLILYRSVITVILLLIMVGVE
MSMEG_0382|M.smegmatis_MC2_155 APLVSDMQHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILLLIMVGFE
MAV_3249|M.avium_104 AALFSDMQLAGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLLLTVGIE
TH_3056|M.thermoresistible__bu AALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVE
Mflv_4418|M.gilvum_PYR-GCK APLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVLILFMVFAE
Mvan_1936|M.vanbaalenii_PYR-1 APLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVLILFMVFAE
MUL_0757|M.ulcerans_Agy99 AALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLG
:.* :* :* :: : :* **:.:**. * ::* *
Mb0458c|M.bovis_AF2122/97 LTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR
Rv0450c|M.tuberculosis_H37Rv LTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR
MLBr_02378|M.leprae_Br4923 SAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEAR
MMAR_0771|M.marinum_M LTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEAR
MAB_4115c|M.abscessus_ATCC_199 LAAARGIVAFLGHHDVFVLSTFAVNMLVFLSIAAGTDYGIFFFGRYQEAR
MSMEG_0382|M.smegmatis_MC2_155 VAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAAGTDYGIFFFGRYQEAR
MAV_3249|M.avium_104 VFAARGVIAFVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFGRYQEAR
TH_3056|M.thermoresistible__bu LQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAR
Mflv_4418|M.gilvum_PYR-GCK LGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEAR
Mvan_1936|M.vanbaalenii_PYR-1 LGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEAR
MUL_0757|M.ulcerans_Agy99 LLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEAR
.:** :* :. . *:*:...:*. : :**.***.** *******
Mb0458c|M.bovis_AF2122/97 QAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPC
Rv0450c|M.tuberculosis_H37Rv QAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPC
MLBr_02378|M.leprae_Br4923 QANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPC
MMAR_0771|M.marinum_M QAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPC
MAB_4115c|M.abscessus_ATCC_199 QAGQDRETAYYTTYRSVAPVVLASGVTIAGAILCLHFTRLPYFQTMGIPC
MSMEG_0382|M.smegmatis_MC2_155 AAGEDRETAYYSMYRGVTPVVMASGLTIAGAIFCLTFTRLPYFHTMGVPC
MAV_3249|M.avium_104 EAGEDRATAYFTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIFQTMGLPC
TH_3056|M.thermoresistible__bu EAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPG
Mflv_4418|M.gilvum_PYR-GCK GAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPC
Mvan_1936|M.vanbaalenii_PYR-1 GAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPC
MUL_0757|M.ulcerans_Agy99 GLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPL
.::: :*::: : .. *::.**:**:** ** *:*:* *..:*:*
Mb0458c|M.bovis_AF2122/97 AVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRW
Rv0450c|M.tuberculosis_H37Rv AVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRW
MLBr_02378|M.leprae_Br4923 AVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRW
MMAR_0771|M.marinum_M AVGMLVAVMVALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRW
MAB_4115c|M.abscessus_ATCC_199 AIGMLAAVAVAVTLVPAGIVVASRFG-LLEPKRKLRVQRWRAIGTAVVRW
MSMEG_0382|M.smegmatis_MC2_155 AIGMLAAVAVAVTLVPAGVALAGRIG-WLEPKRKMRVRRWRGIGTAIVRW
MAV_3249|M.avium_104 SVGMLISVFIALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRIGTAIVRW
TH_3056|M.thermoresistible__bu AVGLLVAVAVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRW
Mflv_4418|M.gilvum_PYR-GCK AVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRIGVSVVRW
Mvan_1936|M.vanbaalenii_PYR-1 AVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGWRRIGVSVVRW
MUL_0757|M.ulcerans_Agy99 AIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRW
::* . * *:** ** : : . :* ::*** ** :*. :***
Mb0458c|M.bovis_AF2122/97 PLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFS
Rv0450c|M.tuberculosis_H37Rv PLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFS
MLBr_02378|M.leprae_Br4923 PLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFP
MMAR_0771|M.marinum_M PLPVLAATLAVALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFS
MAB_4115c|M.abscessus_ATCC_199 PAPILVASLAVALVGLSTLPGYKTSYNDRLYISSDIPANQGFAAAQRHFS
MSMEG_0382|M.smegmatis_MC2_155 PAPILVASLAVALVGLLALPGYETSYNDRDYIPADIPANAGFAAADRHFS
MAV_3249|M.avium_104 PAPILTATIAVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAAADRHFT
TH_3056|M.thermoresistible__bu PVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFP
Mflv_4418|M.gilvum_PYR-GCK PGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQHFG
Mvan_1936|M.vanbaalenii_PYR-1 PGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGYAVADRHFG
MUL_0757|M.ulcerans_Agy99 PGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFS
* *:* : *:::*** :****...*. : ::. :**. *: .* :**
Mb0458c|M.bovis_AF2122/97 QARM-KPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPE
Rv0450c|M.tuberculosis_H37Rv QARM-KPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPE
MLBr_02378|M.leprae_Br4923 QARM-KPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPD
MMAR_0771|M.marinum_M QARM-KPDILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPD
MAB_4115c|M.abscessus_ATCC_199 ESRL-TPDVLLIETDRDLRNPADFLVLNKVAKAIFKVRGVSRVQGITRPE
MSMEG_0382|M.smegmatis_MC2_155 QARM-TPDILMVESDHDMRNPTDFLVLNKIAKAIFKVRGVSRVQGITRPE
MAV_3249|M.avium_104 QSRM-MPELLMIESDHDMRNPADFLVLHRLAKGVFGVHGISRVQGITRPE
TH_3056|M.thermoresistible__bu ASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPE
Mflv_4418|M.gilvum_PYR-GCK SARM-NPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPD
Mvan_1936|M.vanbaalenii_PYR-1 SARM-NPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARVQTITRPD
MUL_0757|M.ulcerans_Agy99 QARM-NPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPD
: : *:::::::*:*:**.:*:*::.::*: :* * *::.** :***:
Mb0458c|M.bovis_AF2122/97 GTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTR
Rv0450c|M.tuberculosis_H37Rv GTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTR
MLBr_02378|M.leprae_Br4923 GTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRR
MMAR_0771|M.marinum_M GTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRR
MAB_4115c|M.abscessus_ATCC_199 GTPIANTSVPFLLSLQSAGQVQATRFQKKRIAEMQKQADDMAKMIATMQR
MSMEG_0382|M.smegmatis_MC2_155 GTPIERTSIPFLLSLQSAGQVQATNFQKQRIGDMLKQVDDMNMMIGVMKT
MAV_3249|M.avium_104 GTPIQHTSIPFLLSMQQATMHQDIQYMKARMDDMLVQADLMRKQIEIMRH
TH_3056|M.thermoresistible__bu GRQIEHTTIPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRR
Mflv_4418|M.gilvum_PYR-GCK GKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQTNVDTMTR
Mvan_1936|M.vanbaalenii_PYR-1 GKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQTNVDTMTK
MUL_0757|M.ulcerans_Agy99 GKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMER
* : .*::** :*: : : : .: *.: : : :
Mb0458c|M.bovis_AF2122/97 MHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWE
Rv0450c|M.tuberculosis_H37Rv MHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWE
MLBr_02378|M.leprae_Br4923 MHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWE
MMAR_0771|M.marinum_M MYGLMTQLANNTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWE
MAB_4115c|M.abscessus_ATCC_199 TYGVMKKMSETTHRMTADTHEVQQITDDLRGSIALFDDFLRPIRNYFYWE
MSMEG_0382|M.smegmatis_MC2_155 TYGVLQELAATTHSLNGSTHELRDVARDLRGSIAIFDDLLRPIRNYFYWE
MAV_3249|M.avium_104 IYELQKRLTDITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRSYFYWE
TH_3056|M.thermoresistible__bu MQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWE
Mflv_4418|M.gilvum_PYR-GCK MQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPVRNYFYWE
Mvan_1936|M.vanbaalenii_PYR-1 MQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPVRNYFYWE
MUL_0757|M.ulcerans_Agy99 MHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWE
: : ** .:*. :: ::*: **:*.**:**
Mb0458c|M.bovis_AF2122/97 KHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQI
Rv0450c|M.tuberculosis_H37Rv KHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQI
MLBr_02378|M.leprae_Br4923 RHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQF
MMAR_0771|M.marinum_M KHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETF
MAB_4115c|M.abscessus_ATCC_199 KHCFDIPICWSIRSIFDALDGADALDDGLVELVKNMDKLDAIMPQLLVQF
MSMEG_0382|M.smegmatis_MC2_155 PHCYNIPICWSLRSIFDAMDGVDRLNDELQVLVDNMDRLDALVPELVAQF
MAV_3249|M.avium_104 KHCYDIPICWSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQLLEQY
TH_3056|M.thermoresistible__bu PHCYNIPICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQF
Mflv_4418|M.gilvum_PYR-GCK PHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALL
Mvan_1936|M.vanbaalenii_PYR-1 PHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALMPQLIALL
MUL_0757|M.ulcerans_Agy99 KHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMM
**:.**:* ::*.:*:::** : : : : :: : .:* ::*::
Mb0458c|M.bovis_AF2122/97 PPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDS
Rv0450c|M.tuberculosis_H37Rv PPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDS
MLBr_02378|M.leprae_Br4923 PPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDS
MMAR_0771|M.marinum_M PPMIETMESMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDS
MAB_4115c|M.abscessus_ATCC_199 PQMIEVMQSMRTSVLTMYATMSGQFAQMDETTDDVMAMGEAFDASKNDDS
MSMEG_0382|M.smegmatis_MC2_155 PEYIASMETFRELTLTSYSTFSGLLQQMDEQTEDVTAMGQAFDAAKNDDT
MAV_3249|M.avium_104 PPMIAMSEDMLRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFDASKNDDS
TH_3056|M.thermoresistible__bu PQMIETMESSRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDS
Mflv_4418|M.gilvum_PYR-GCK PSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDS
Mvan_1936|M.vanbaalenii_PYR-1 PSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFDDSMNDDS
MUL_0757|M.ulcerans_Agy99 PEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDS
* * . * : : * * .: :**:*** : ***:
Mb0458c|M.bovis_AF2122/97 FYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAI
Rv0450c|M.tuberculosis_H37Rv FYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAI
MLBr_02378|M.leprae_Br4923 FYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAI
MMAR_0771|M.marinum_M FYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQI
MAB_4115c|M.abscessus_ATCC_199 FFLPPEVFKNPDFQRAMSSFLSPDGKTVRFIISHNGDPMSPEGIARIEQV
MSMEG_0382|M.smegmatis_MC2_155 FFLPPEVFDNPDFKRAMTSFLSPDGKAARFIISHNGDPATPEGISRVDQM
MAV_3249|M.avium_104 FYLPPDIFDNADFKKAMSQFLSPDGKAARFIISHRGDPATSEALNRIDKI
TH_3056|M.thermoresistible__bu FYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPI
Mflv_4418|M.gilvum_PYR-GCK FYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEGISEVVPI
Mvan_1936|M.vanbaalenii_PYR-1 FYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEGISRVLPI
MUL_0757|M.ulcerans_Agy99 FYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKI
*:***: :.* **:: : *:*.**::.*::: :.*** : .: : :
Mb0458c|M.bovis_AF2122/97 RTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIF
Rv0450c|M.tuberculosis_H37Rv RTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIF
MLBr_02378|M.leprae_Br4923 RTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIF
MMAR_0771|M.marinum_M RTAAEESLKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIF
MAB_4115c|M.abscessus_ATCC_199 RNAAEEALKGTPLVGGKVYIAGAASTAKDWKDGSTYDLLIAGIAAICLVF
MSMEG_0382|M.smegmatis_MC2_155 QTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGSTYDLLIAGIAAMCLIF
MAV_3249|M.avium_104 RSAAEEALKNTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGALCLIF
TH_3056|M.thermoresistible__bu YIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIF
Mflv_4418|M.gilvum_PYR-GCK KTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLIF
Mvan_1936|M.vanbaalenii_PYR-1 KTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGIAAVTLIF
MUL_0757|M.ulcerans_Agy99 KTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIF
** *::*.*** . :*:.*:.. :* :* :**.**.:.:: *:*
Mb0458c|M.bovis_AF2122/97 IIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAM
Rv0450c|M.tuberculosis_H37Rv IIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAM
MLBr_02378|M.leprae_Br4923 IIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAM
MMAR_0771|M.marinum_M IIMLILTRAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAM
MAB_4115c|M.abscessus_ATCC_199 IIMLITTRSFIAALVIVGTVALSLGASFGLSVLLWQYILGVNLHWMVLAM
MSMEG_0382|M.smegmatis_MC2_155 IIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLLWQYILGIHLHWMVLAM
MAV_3249|M.avium_104 IIMLILTRSFIAALVIVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLPM
TH_3056|M.thermoresistible__bu MIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAM
Mflv_4418|M.gilvum_PYR-GCK VIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPM
Mvan_1936|M.vanbaalenii_PYR-1 VIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPM
MUL_0757|M.ulcerans_Agy99 IIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAM
:**:. **:.:** ****** ********:***:**::: : *:::**.*
Mb0458c|M.bovis_AF2122/97 SVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVF
Rv0450c|M.tuberculosis_H37Rv SVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVF
MLBr_02378|M.leprae_Br4923 SVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVF
MMAR_0771|M.marinum_M SVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVF
MAB_4115c|M.abscessus_ATCC_199 SVIILLAVGSDYNLLLVSRMKEELGAGLNTGIIRAMGGTGKVVTSAGLVF
MSMEG_0382|M.smegmatis_MC2_155 SVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVRAMGGTGKVVTSAGLVF
MAV_3249|M.avium_104 SVIVLLAVGSDYNLLLVSRMKEEISAGINTGIIRAMGGTGKVVTNAGLVF
TH_3056|M.thermoresistible__bu SVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVF
Mflv_4418|M.gilvum_PYR-GCK AVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVVTSAGLVF
Mvan_1936|M.vanbaalenii_PYR-1 AVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVVTSAGLVF
MUL_0757|M.ulcerans_Agy99 AVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVF
:**:*****:****:**:*:*:*: .*::***:*:*.*:* *** *****
Mb0458c|M.bovis_AF2122/97 AVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW
Rv0450c|M.tuberculosis_H37Rv AVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW
MLBr_02378|M.leprae_Br4923 AFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFW
MMAR_0771|M.marinum_M AFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFW
MAB_4115c|M.abscessus_ATCC_199 AATMASMVVSDLQIIGQIGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFW
MSMEG_0382|M.smegmatis_MC2_155 AGTMAAMVVSDLRIIGQIGTTIGLGLLFDTMIVRSFMTPSIAALLGRWFW
MAV_3249|M.avium_104 AFTMASMVVSDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFW
TH_3056|M.thermoresistible__bu AATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFW
Mflv_4418|M.gilvum_PYR-GCK AFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFW
Mvan_1936|M.vanbaalenii_PYR-1 AFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFW
MUL_0757|M.ulcerans_Agy99 AFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFW
* ** :: .*:* ::.*:****.:**:***::**:** *::**:**:***
Mb0458c|M.bovis_AF2122/97 WPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------------
Rv0450c|M.tuberculosis_H37Rv WPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------------
MLBr_02378|M.leprae_Br4923 WPQQGRTRPLLTVAAPVGLP-PDRSLVYSD--------------------
MMAR_0771|M.marinum_M WPMRVRTRPARTPSSPTADPEPDRALAMSGER------------------
MAB_4115c|M.abscessus_ATCC_199 WPQRVRPRPPSALLTPVGASAPSAWHTDARHDDEGPTAELPRLSE-----
MSMEG_0382|M.smegmatis_MC2_155 WPQKVRPRPASALLEPYGPRPLVRALLEGPSGAASPGGPGGRLSDDDTPT
MAV_3249|M.avium_104 WPQLVRRRPASQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRPTA---
TH_3056|M.thermoresistible__bu WPQRVRTRPASAMLRPVGPRPLVRSLLLRD--------------------
Mflv_4418|M.gilvum_PYR-GCK WPQKFRSAASERRLARIGVQPATAGR------------------------
Mvan_1936|M.vanbaalenii_PYR-1 WPQKVRSHASQRRLAALNH-------------------------------
MUL_0757|M.ulcerans_Agy99 WPQVVRQRPAPQPWPTPAPTPPPATTSV----------------------
** * .
Mb0458c|M.bovis_AF2122/97 ------
Rv0450c|M.tuberculosis_H37Rv ------
MLBr_02378|M.leprae_Br4923 ------
MMAR_0771|M.marinum_M ------
MAB_4115c|M.abscessus_ATCC_199 ------
MSMEG_0382|M.smegmatis_MC2_155 GPMRTR
MAV_3249|M.avium_104 ------
TH_3056|M.thermoresistible__bu ------
Mflv_4418|M.gilvum_PYR-GCK ------
Mvan_1936|M.vanbaalenii_PYR-1 ------
MUL_0757|M.ulcerans_Agy99 ------