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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3056 | - | - | 100% (961) | Mmp14a protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 54.69% (938) | PUTATIVE MmpL4 protein |
M. thermoresistible (build 8) | TH_2972 | - | 0.0 | 66.08% (566) | PUTATIVE putative transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 62.66% (948) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 58.25% (939) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 62.76% (948) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 59.77% (947) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4116c | - | 0.0 | 72.09% (953) | putative membrane protein, MmpL |
M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 62.55% (940) | transmembrane transport protein MmpL5_2 |
M. avium 104 | MAV_3248 | - | 0.0 | 64.56% (948) | Mmp14A protein |
M. smegmatis MC2 155 | MSMEG_0381 | - | 0.0 | 75.42% (948) | Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 55.94% (942) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 58.57% (934) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDT--HTKPPFVARMIHRFAVPIILVWLAIAVTVSVFI MMAR_0771|M.marinum_M ----MTVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVFI MAB_4116c|M.abscessus_ATCC_199 ---------MSADDGKVKSHRPIMATIIRRGAVFIILGWLAITVLLTVKV MSMEG_0381|M.smegmatis_MC2_155 --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV MAV_3248|M.avium_104 --------MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGV MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRPFIPRMIRLFAVPIILGWIALIVILNVTV Mflv_4418|M.gilvum_PYR-GCK ---------------MADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVAV . : :*: :* ::* *: : . . : Mb0458c|M.bovis_AF2122/97 PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP Rv0450c|M.tuberculosis_H37Rv PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP MLBr_02378|M.leprae_Br4923 PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGDKP MMAR_0771|M.marinum_M PSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGKDA MAB_4116c|M.abscessus_ATCC_199 PPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGEGT MSMEG_0381|M.smegmatis_MC2_155 PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQEP TH_3056|M.thermoresistible__bu PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQEP MAV_3248|M.avium_104 PSLEQVEAEHAVSLSPIGAPSFKAMERLGEDFKETNTGALAMILLEGQQQ MUL_0757|M.ulcerans_Agy99 PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQEP Mvan_3189|M.vanbaalenii_PYR-1 PQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIVFEGDQP Mflv_4418|M.gilvum_PYR-GCK PSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFDSDSSAMVVLEGEQP * ** * :::.: . **: :* ::* * * :: : ::::**. Mb0458c|M.bovis_AF2122/97 LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ Rv0450c|M.tuberculosis_H37Rv LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ MLBr_02378|M.leprae_Br4923 LGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAYVQ MMAR_0771|M.marinum_M LGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAYVQ MAB_4116c|M.abscessus_ATCC_199 LGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAYVQ MSMEG_0381|M.smegmatis_MC2_155 LGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAYVQ TH_3056|M.thermoresistible__bu LGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAFVQ MAV_3248|M.avium_104 LGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAYVQ MUL_0757|M.ulcerans_Agy99 LGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAYVQ Mvan_3189|M.vanbaalenii_PYR-1 LGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDGKAAYVQ Mflv_4418|M.gilvum_PYR-GCK LGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQSTDGKAAYVQ ** ** :** :: *. . ** : ::*.**** . :* * ***:** Mb0458c|M.bovis_AF2122/97 LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS Rv0450c|M.tuberculosis_H37Rv LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS MLBr_02378|M.leprae_Br4923 LSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMHHS MMAR_0771|M.marinum_M LNLAGNQGEPLANESVEAVRKIVKETP-APPGVTTYVTGAAALVSDMHSS MAB_4116c|M.abscessus_ATCC_199 LNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMAES MSMEG_0381|M.smegmatis_MC2_155 INLHGSFGQAEANESVKAVQDAVESTP-APPGVQAFVTGPAAIVADMGES TH_3056|M.thermoresistible__bu VNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAGDS MAV_3248|M.avium_104 VNLNGNAGAAAGDESVAAIRKLVQEAS-PPPGLKVYVTGPAPIVADMNIA MUL_0757|M.ulcerans_Agy99 VKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQLA Mvan_3189|M.vanbaalenii_PYR-1 VKLAGNQGESLANESVQAAQEIVRSLE-PPPGVRAFVTGPAALAADQHIA Mflv_4418|M.gilvum_PYR-GCK VYLQGNQGEPRANEAVAAVREIVDRTP-APPGIKAYVTGGAPLVADQHSA : * * * :*:: * : * * *: .:*** :.: :* : Mb0458c|M.bovis_AF2122/97 GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV Rv0450c|M.tuberculosis_H37Rv GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV MLBr_02378|M.leprae_Br4923 GDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVAL MMAR_0771|M.marinum_M GDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVELTAARGVVAL MAB_4116c|M.abscessus_ATCC_199 GNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLVAF MSMEG_0381|M.smegmatis_MC2_155 GNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLVSF TH_3056|M.thermoresistible__bu GTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVAY MAV_3248|M.avium_104 GQKTVMLVTLASLIVIFVTLLLVYRSVITVILLLLIVGLELQIARGMVAL MUL_0757|M.ulcerans_Agy99 GDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVAF Mvan_3189|M.vanbaalenii_PYR-1 SDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSLATARGVVAF Mflv_4418|M.gilvum_PYR-GCK GDTSVLRVTLITIGVIAVMLLIVFRSVATMVLILFMVFAELGAARGIVAF . :: : :. ** : **:.:* . : * * :** *: Mb0458c|M.bovis_AF2122/97 LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY Rv0450c|M.tuberculosis_H37Rv LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY MLBr_02378|M.leprae_Br4923 LGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAF MMAR_0771|M.marinum_M LGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEARQAGEDKETAF MAB_4116c|M.abscessus_ATCC_199 LGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRESAY MSMEG_0381|M.smegmatis_MC2_155 LALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQAY TH_3056|M.thermoresistible__bu LGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSAY MAV_3248|M.avium_104 LGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEARQAGESREEAF MUL_0757|M.ulcerans_Agy99 LGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESAY Mvan_3189|M.vanbaalenii_PYR-1 LGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEARTNGEDKESAY Mflv_4418|M.gilvum_PYR-GCK LADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRETAY *. :**: :...**. **:.***.** ******* .:.:: *: Mb0458c|M.bovis_AF2122/97 YTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAVAV Rv0450c|M.tuberculosis_H37Rv YTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAV MLBr_02378|M.leprae_Br4923 YTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAV MMAR_0771|M.marinum_M YTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPCAVGMLVAVMV MAB_4116c|M.abscessus_ATCC_199 YTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAVAV MSMEG_0381|M.smegmatis_MC2_155 YTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVAV TH_3056|M.thermoresistible__bu FTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVAV MAV_3248|M.avium_104 YTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAVLV MUL_0757|M.ulcerans_Agy99 YTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAT Mvan_3189|M.vanbaalenii_PYR-1 YTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPLAIGMFVVVMA Mflv_4418|M.gilvum_PYR-GCK YTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIA :* : .. :*:*.** **:** ** *:*:*:*:.:*:* *:* :.* . Mb0458c|M.bovis_AF2122/97 ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA Rv0450c|M.tuberculosis_H37Rv ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA MLBr_02378|M.leprae_Br4923 ALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITTCA MMAR_0771|M.marinum_M ALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRWPLPVLAATLA MAB_4116c|M.abscessus_ATCC_199 ALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAATVA MSMEG_0381|M.smegmatis_MC2_155 ALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIATIA TH_3056|M.thermoresistible__bu ALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAVA MAV_3248|M.avium_104 ALTLGPALLAAGARFG-LFEPRRAVSARRWRRIGTAIVRWPAPILIATLA MUL_0757|M.ulcerans_Agy99 ALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAVA Mvan_3189|M.vanbaalenii_PYR-1 GVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRWPGPILVATLA Mflv_4418|M.gilvum_PYR-GCK ALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLA .: * * : *** ::*:* : **::*. :**** *:* : * Mb0458c|M.bovis_AF2122/97 IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEIL Rv0450c|M.tuberculosis_H37Rv IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PEIL MLBr_02378|M.leprae_Br4923 IAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PEIL MMAR_0771|M.marinum_M VALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFSQARMK-PDIL MAB_4116c|M.abscessus_ATCC_199 VALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPDIL MSMEG_0381|M.smegmatis_MC2_155 VAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPDIL TH_3056|M.thermoresistible__bu LSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPDVV MAV_3248|M.avium_104 VSLVGLLALPNYRPSYDDQKFIPDSIPANVGYAAAARHFPGQRMQMPEIL MUL_0757|M.ulcerans_Agy99 LALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PEVL Mvan_3189|M.vanbaalenii_PYR-1 ITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFDQARMN-PELL Mflv_4418|M.gilvum_PYR-GCK LALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQHFGSARMN-PELL ::::**::**.*...* ::* :**. * .* :** * *::: Mb0458c|M.bovis_AF2122/97 MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP Rv0450c|M.tuberculosis_H37Rv MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP MLBr_02378|M.leprae_Br4923 MIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSIP MMAR_0771|M.marinum_M MIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPDGTAMDHTSIP MAB_4116c|M.abscessus_ATCC_199 LIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSSVP MSMEG_0381|M.smegmatis_MC2_155 LVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSIP TH_3056|M.thermoresistible__bu LIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTIP MAV_3248|M.avium_104 LVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTTIP MUL_0757|M.ulcerans_Agy99 MVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSIP Mvan_3189|M.vanbaalenii_PYR-1 MIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDGKPIKHTSIP Mflv_4418|M.gilvum_PYR-GCK MVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPDGKPIKHTTIP ::::::*:**.:*:*:::::*: :: * *:: **::***:* :.*:::* Mb0458c|M.bovis_AF2122/97 FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS Rv0450c|M.tuberculosis_H37Rv FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS MLBr_02378|M.leprae_Br4923 FQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLTE MMAR_0771|M.marinum_M FQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRRMYGLMTQLAN MAB_4116c|M.abscessus_ATCC_199 FMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQMVD MSMEG_0381|M.smegmatis_MC2_155 FMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMVA TH_3056|M.thermoresistible__bu FMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKMVA MAV_3248|M.avium_104 WIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMRELVA MUL_0757|M.ulcerans_Agy99 FLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMAD Mvan_3189|M.vanbaalenii_PYR-1 FQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKMSNLTAQMAD Mflv_4418|M.gilvum_PYR-GCK FQMSMQGTTQRLNEKYLQDRMADMLVQADAMQTNVDTMTRMQSLMGQMSA : :** : * : : .:* *.: : : : :* * : Mb0458c|M.bovis_AF2122/97 TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW Rv0450c|M.tuberculosis_H37Rv TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW MLBr_02378|M.leprae_Br4923 NTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPICW MMAR_0771|M.marinum_M NTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWEKHCYDIPICS MAB_4116c|M.abscessus_ATCC_199 TTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPICW MSMEG_0381|M.smegmatis_MC2_155 TTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPLCW TH_3056|M.thermoresistible__bu TTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPICW MAV_3248|M.avium_104 TTHHMVQTTHEMQEITGELRDHISDFEDFWRPLRSYFYWEKHCYDIPICF MUL_0757|M.ulcerans_Agy99 VTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPVCW Mvan_3189|M.vanbaalenii_PYR-1 ITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEPHCYNIPVCW Mflv_4418|M.gilvum_PYR-GCK TTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPVRNYFYWEPHCYDIPVCW ** : :*: : :*:**:**:*.*::*: **:.**:* Mb0458c|M.bovis_AF2122/97 SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM Rv0450c|M.tuberculosis_H37Rv SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM MLBr_02378|M.leprae_Br4923 SFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESMESM MMAR_0771|M.marinum_M SFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETFPPMIETMESM MAB_4116c|M.abscessus_ATCC_199 SIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMKST MSMEG_0381|M.smegmatis_MC2_155 SIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLENS TH_3056|M.thermoresistible__bu SIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETMESS MAV_3248|M.avium_104 SLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQIPPMIETMSGM MUL_0757|M.ulcerans_Agy99 SLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMKSM Mvan_3189|M.vanbaalenii_PYR-1 ALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMPEMIETMKTM Mflv_4418|M.gilvum_PYR-GCK TMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALLPSQIETMRSM ::**:** ***:: : : : :: : .:* ::**: :* * : Mb0458c|M.bovis_AF2122/97 RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN Rv0450c|M.tuberculosis_H37Rv RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN MLBr_02378|M.leprae_Br4923 RTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFKN MMAR_0771|M.marinum_M RLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDSFYLPPEVFKN MAB_4116c|M.abscessus_ATCC_199 RESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVLKN MSMEG_0381|M.smegmatis_MC2_155 RSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILEN TH_3056|M.thermoresistible__bu RTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEALEN MAV_3248|M.avium_104 RTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGIING MUL_0757|M.ulcerans_Agy99 KAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFNN Mvan_3189|M.vanbaalenii_PYR-1 RTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFYLPPEIFEN Mflv_4418|M.gilvum_PYR-GCK QAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDSFYLPPEAFDN : :* : : * * .:. :**:*** : ********* :.. Mb0458c|M.bovis_AF2122/97 KD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK Rv0450c|M.tuberculosis_H37Rv KD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLK MLBr_02378|M.leprae_Br4923 TD-FKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALK MMAR_0771|M.marinum_M ED-FKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQIRTAAEESLK MAB_4116c|M.abscessus_ATCC_199 KD-FQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEALK MSMEG_0381|M.smegmatis_MC2_155 ED-FKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALK TH_3056|M.thermoresistible__bu KD-FQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEALK MAV_3248|M.avium_104 SDSFKRVEKVFMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEESLK MUL_0757|M.ulcerans_Agy99 PD-FKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIK Mvan_3189|M.vanbaalenii_PYR-1 KD-FQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKTAAKEAIK Mflv_4418|M.gilvum_PYR-GCK DD-FKRGMENFISPDGRSVRFIISHEGDPATVEGISEVVPIKTAAKEAIK * *:* : *:*.**: *::: :.*** : *: : * **:*::* Mb0458c|M.bovis_AF2122/97 GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA Rv0450c|M.tuberculosis_H37Rv GTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRA MLBr_02378|M.leprae_Br4923 GTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITRA MMAR_0771|M.marinum_M GTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIFIIMLILTRA MAB_4116c|M.abscessus_ATCC_199 GTPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMTRS MSMEG_0381|M.smegmatis_MC2_155 GTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMTRS TH_3056|M.thermoresistible__bu GTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRS MAV_3248|M.avium_104 GTPLENSKIYLTGTAAITKDLVDGSKFDLLIAGVSALCLIFIIMLIMTRS MUL_0757|M.ulcerans_Agy99 GTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRS Mvan_3189|M.vanbaalenii_PYR-1 GTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIFIIMLILTRA Mflv_4418|M.gilvum_PYR-GCK GTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLIFVIMLVITRS ***** : : : *:.: :: :* **:**.:::: ***:**:.:**: Mb0458c|M.bovis_AF2122/97 FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG Rv0450c|M.tuberculosis_H37Rv FIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVG MLBr_02378|M.leprae_Br4923 FVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVG MMAR_0771|M.marinum_M FVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAMSVIVLLAVG MAB_4116c|M.abscessus_ATCC_199 LVAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLAVG MSMEG_0381|M.smegmatis_MC2_155 FIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVG TH_3056|M.thermoresistible__bu VIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVG MAV_3248|M.avium_104 FIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLAVG MUL_0757|M.ulcerans_Agy99 VVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVG Mvan_3189|M.vanbaalenii_PYR-1 IVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAMAVIVLLAVG Mflv_4418|M.gilvum_PYR-GCK VVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVG .:** ****** :**.****:***.**:: ::: **. :**:***** Mb0458c|M.bovis_AF2122/97 SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV Rv0450c|M.tuberculosis_H37Rv SDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAV MLBr_02378|M.leprae_Br4923 SDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVV MMAR_0771|M.marinum_M SDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVFAFTMASMAV MAB_4116c|M.abscessus_ATCC_199 SDYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSMIV MSMEG_0381|M.smegmatis_MC2_155 SDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIV TH_3056|M.thermoresistible__bu SDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIV MAV_3248|M.avium_104 SDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAMVV MUL_0757|M.ulcerans_Agy99 ADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAV Mvan_3189|M.vanbaalenii_PYR-1 ADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFALTMMSMAV Mflv_4418|M.gilvum_PYR-GCK SDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVVTSAGLVFAFTMASFAF :****:**:*:*:*: .*: *****:*.*:* *** ****** ** :: . Mb0458c|M.bovis_AF2122/97 SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP Rv0450c|M.tuberculosis_H37Rv SDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRP MLBr_02378|M.leprae_Br4923 SDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRP MMAR_0771|M.marinum_M SDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFWWPMRVRTRP MAB_4116c|M.abscessus_ATCC_199 SDLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSPRP MSMEG_0381|M.smegmatis_MC2_155 SDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRP TH_3056|M.thermoresistible__bu SDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRP MAV_3248|M.avium_104 SDLRSIGQVGTTIGLGLLFDTLIVRAFMTPSVAALLGRWFWWPQLVRPRP MUL_0757|M.ulcerans_Agy99 SELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRP Mvan_3189|M.vanbaalenii_PYR-1 SELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWPQRVRTRP Mflv_4418|M.gilvum_PYR-GCK SDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFWWPQKFRSAA *:* :.******.:******:::*:** *::**:** ***** . Mb0458c|M.bovis_AF2122/97 ARTPTVPSETQPAGRPLAMSSDRLG Rv0450c|M.tuberculosis_H37Rv ARTPTVPSETQPAGRPLAMSSDRLG MLBr_02378|M.leprae_Br4923 LLTVAAPVGLP-PDRSLVYSD---- MMAR_0771|M.marinum_M ARTPSSPTADPEPDRALAMSGER-- MAB_4116c|M.abscessus_ATCC_199 VGAVRGWRGPR-LVRSVLQRN---- MSMEG_0381|M.smegmatis_MC2_155 ASAMLRSVGPRPLVRSLLLRD---- TH_3056|M.thermoresistible__bu ASAMLRPVGPRPLVRSLLLRD---- MAV_3248|M.avium_104 ASTMLRPTGPRPLVRSLLLKQPQ-- MUL_0757|M.ulcerans_Agy99 APQPWPTPAPTPPPATTSV------ Mvan_3189|M.vanbaalenii_PYR-1 VPAPWPRPGGLQSDPSEGVKV---- Mflv_4418|M.gilvum_PYR-GCK SERRLARIGVQPATAGR--------