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MSTHSAPTHGAAQKPSRIARFIHTFSVPIILAWLVLTVIVNVVVPQLEEVGKEHSVSLASKDAPSYQAIK RQGELFQQFKDDSMVMVLLENDTKFSTDMNDKAHTFYRELVKRLRADTKHVEYAQDFWGDRITAGGAQSV DEKAAYVQLNLRGDQGTTEGKESVTAVQDNVAKLIDESKKNGTYPDGLKVFVTGQAALTMDMNDAGDKSM LKMTGITFIVITIMLLFIYRSITTVLLILFMVFVELGAARGVVAILGNAEIIGLSTFAVNLLTSLAIAAG TDYAIFLIGRYQELRAEGKERLESFYLTYHSVSHVILGSGLTIAGATFCLKFTRLPYFESLGVPCAIGML VVVAASLTIGPAVLLVATKFGLLESKRTIKNRTWRKVGTAIVRWPGPILAVTMIIALLGLGILPSYTVNY NDRYYIPASLPSIQGFQASDRHFSKARMNPDILIVEADKDLRTPANMLVLDRIAKNVFRVEGINKVQSMT RPMGAPIDHSSVPFQVSMQSVSMTENMNYLKNSMSDMLKMTDDMGSMIAIMERMYSLMKELTGVTHHMAT VTTPDMIHVADEMRDNMANFDDFYRPLRNYLYWEKHCFDIPMCWSMRSLFDALDGIDKLTESMRGLLDDV TNMDKLMPQVVEQLPPMIAITKNMRNTMLTMYSTMNGMIGQMDRMTDTATVMGQAFDEAKNDDFFYLPPE AFDNEDFKKGVKLMMSPDGKAAQFIITHEGDYASNESLANTEVELKAAKEAIKGTPLDESKLYLGGTAPT YHDIGEMVKYDLMIAVIASLCLIFVIMLVITRSIVAAFTIVGTIAVSLGASFGLSVLLWEHILGLQLHWF VLPFTVIILLAVGSDYNLLLVSRFKEELHGGLNTAILRGVGGSGSVATQAGLVFAFTMGSMITSDLIAIG QSGSAICLGLLFDTFIIRAFMTPAIAALMGRWFWWPMKVSKYATDPPPPPVPVESQTPPPPAPVPVGPSP GPAHDDAVTTEFPRPPV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2303 | - | - | 100% (997) | putative membrane protein, MmpL |
M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 56.67% (990) | putative membrane protein, mmpL |
M. abscessus ATCC 19977 | MAB_1134c | - | 0.0 | 56.55% (985) | membrane protein MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 56.15% (967) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 54.79% (940) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 56.26% (967) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 56.68% (935) | hypothetical protein MLBr_02378 |
M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 56.87% (953) | transmembrane transport protein MmpL5_2 |
M. avium 104 | MAV_2510 | - | 0.0 | 55.42% (951) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 54.55% (977) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 52.55% (982) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 54.27% (949) | transmembrane transport protein MmpL4_1 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 54.95% (939) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 MSTKFANDSNTNARPEKP------------------FIARMIHAFAVPII Rv0450c|M.tuberculosis_H37Rv MSTKFANDSNTNARPEKP------------------FIARMIHAFAVPII MLBr_02378|M.leprae_Br4923 MTVKCANDLDT--HTKPP------------------FVARMIHRFAVPII MMAR_0771|M.marinum_M MTVKYANDPDTRTHTEKP------------------FLARMIHAFAVPII Mflv_4418|M.gilvum_PYR-GCK MADAGRSG-----------------------------IGRIIRVLAVPIV Mvan_1936|M.vanbaalenii_PYR-1 MADAGRSG-----------------------------IGRIIHLLAVPIV MAV_2510|M.avium_104 MSTTFDDTRTDAIPVV--KEPVREK------------IPRFIRAFAVPII MSMEG_3496|M.smegmatis_MC2_155 MSNPSHDAPTDAMGVSGPKHARPGG------------IAKWIRVLAVPII TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPS--------FISTWIRRLSLPII MUL_3688|M.ulcerans_Agy99 MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPII MAB_2303|M.abscessus_ATCC_1997 MSTHSAPTHGAAQKPSR--------------------IARFIHTFSVPII *: : *: :::**: Mb0458c|M.bovis_AF2122/97 LGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGD Rv0450c|M.tuberculosis_H37Rv LGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGD MLBr_02378|M.leprae_Br4923 LVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGN MMAR_0771|M.marinum_M LAWVAVCVALSVFIPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGN Mflv_4418|M.gilvum_PYR-GCK LGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFD Mvan_1936|M.vanbaalenii_PYR-1 LGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFD MAV_2510|M.avium_104 IGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYK MSMEG_3496|M.smegmatis_MC2_155 LVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFK TH_3260|M.thermoresistible__bu VGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGS MUL_3688|M.ulcerans_Agy99 LGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFREFD MAB_2303|M.abscessus_ATCC_1997 LAWLVLTVIVNVVVPQLEEVGKEHSVSLASKDAPSYQAIKRQGELFQQFK : *: : . . :*.*: *.: ::. ::. :* * : : * * : . Mb0458c|M.bovis_AF2122/97 SDSFAMVIIEGNQPLG----DAAHKYYDGLVAQLRADKKHVQSVQDLWGD Rv0450c|M.tuberculosis_H37Rv SDSFAMVIIEGNQPLG----DAAHKYYDGLVAQLRADKKHVQSVQDLWGD MLBr_02378|M.leprae_Br4923 SDSVIMIVLEGDKPLG----DDAHRFYDGLIRKLRAD-KHVQSVQDFWGD MMAR_0771|M.marinum_M SDSQAMIVLEGKDALG----DDAHKYYDVLIRKLRADPRHVQSVQDFWGD Mflv_4418|M.gilvum_PYR-GCK SDSSAMVVLEGEQPLG----DAAHRYYDQLIDELEADTANVQHIADFWGD Mvan_1936|M.vanbaalenii_PYR-1 SDSSAMVVLEGEQPLG----DAAHRYYDELIGKLEADTANVQHVADFWGD MAV_2510|M.avium_104 SNSSVMIVLEGQQPLG----ADAHAYYDEIVRRLNADTKHVEHVQDMWSD MSMEG_3496|M.smegmatis_MC2_155 SNSSVMIVLEGEQPLG----DEAHKYYDEIVDKLEADPAHVEHVQDFWGD TH_3260|M.thermoresistible__bu SDSQVMIVLEGEEPLG----ADARAFYDELVKRLEADDAHVENVQDLWSD MUL_3688|M.ulcerans_Agy99 SNSTVMIVLEGQHKLG----DDAHQYYDSLIRQLRQDPEHIQHIQDFWGD MAB_2303|M.abscessus_ATCC_1997 DDSMVMVLLENDTKFSTDMNDKAHTFYRELVKRLRADTKHVEYAQDFWGD .:* *:::*.. :. *: :* :: .*. * ::: *:*.* Mb0458c|M.bovis_AF2122/97 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST------ Rv0450c|M.tuberculosis_H37Rv PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST------ MLBr_02378|M.leprae_Br4923 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT------ MMAR_0771|M.marinum_M PLTAAGAQSNDGKAAYVQLNLAGNQGEPLANESVEAVRKIVKET------ Mflv_4418|M.gilvum_PYR-GCK PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT------ Mvan_1936|M.vanbaalenii_PYR-1 PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQT------ MAV_2510|M.avium_104 PLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSV------ MSMEG_3496|M.smegmatis_MC2_155 PLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESV------ TH_3260|M.thermoresistible__bu PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE--- MUL_3688|M.ulcerans_Agy99 RLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT------ MAB_2303|M.abscessus_ATCC_1997 RITAGGAQSVDEKAAYVQLNLRGDQGTTEGKESVTAVQDNVAKLIDESKK :*. *.** * ::** : *:** .:*:: :*:. : Mb0458c|M.bovis_AF2122/97 --PAPPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYR Rv0450c|M.tuberculosis_H37Rv --PAPPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYR MLBr_02378|M.leprae_Br4923 --PAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYR MMAR_0771|M.marinum_M --PAPPGVTTYVTGAAALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYR Mflv_4418|M.gilvum_PYR-GCK --PAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFR Mvan_1936|M.vanbaalenii_PYR-1 --PAPPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFR MAV_2510|M.avium_104 --QAPNGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYR MSMEG_3496|M.smegmatis_MC2_155 --PAPPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYR TH_3260|M.thermoresistible__bu --MAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYR MUL_3688|M.ulcerans_Agy99 --HEPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYR MAB_2303|M.abscessus_ATCC_1997 NGTYPDGLKVFVTGQAALTMDMNDAGDKSMLKMTGITFIVITIMLLFIYR * *: .:*** :.: * : .: *: : :. .* **:::* Mb0458c|M.bovis_AF2122/97 SIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAG Rv0450c|M.tuberculosis_H37Rv SIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAG MLBr_02378|M.leprae_Br4923 SFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAG MMAR_0771|M.marinum_M SVITVVVLLLTVGVELTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAG Mflv_4418|M.gilvum_PYR-GCK SVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAG Mvan_1936|M.vanbaalenii_PYR-1 SVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAG MAV_2510|M.avium_104 SVITVLLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAA MSMEG_3496|M.smegmatis_MC2_155 SIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAA TH_3260|M.thermoresistible__bu SVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIA MUL_3688|M.ulcerans_Agy99 SIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAG MAB_2303|M.abscessus_ATCC_1997 SITTVLLILFMVFVELGAARGVVAILGNAEIIGLSTFAVNLLTSLAIAAG *. * :: *. . :**::*.*. :**:.**..:*. :.** . Mb0458c|M.bovis_AF2122/97 TDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCL Rv0450c|M.tuberculosis_H37Rv TDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCL MLBr_02378|M.leprae_Br4923 TDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCL MMAR_0771|M.marinum_M TDYGIFIFGRYQEARQAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCL Mflv_4418|M.gilvum_PYR-GCK TDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCL Mvan_1936|M.vanbaalenii_PYR-1 TDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCL MAV_2510|M.avium_104 TDYAIFLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCL MSMEG_3496|M.smegmatis_MC2_155 TDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCL TH_3260|M.thermoresistible__bu VDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCL MUL_3688|M.ulcerans_Agy99 TDYGIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCL MAB_2303|M.abscessus_ATCC_1997 TDYAIFLIGRYQELRAEGKERLESFYLTYHSVSHVILGSGLTIAGATFCL .**.** ***** * . .: ::: : .. *: .**:**:** ** Mb0458c|M.bovis_AF2122/97 SFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLL Rv0450c|M.tuberculosis_H37Rv SFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLL MLBr_02378|M.leprae_Br4923 SFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLI MMAR_0771|M.marinum_M KFARMPYFETLGIPCAVGMLVAVMVALTLGPAVLTVGSRFG-LFDPKRLI Mflv_4418|M.gilvum_PYR-GCK SFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAI Mvan_1936|M.vanbaalenii_PYR-1 SFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAI MAV_2510|M.avium_104 HFTNLPYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQ MSMEG_3496|M.smegmatis_MC2_155 HFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAM TH_3260|M.thermoresistible__bu SFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAA MUL_3688|M.ulcerans_Agy99 SFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-PFESKRAA MAB_2303|M.abscessus_ATCC_1997 KFTRLPYFESLGVPCAIGMLVVVAASLTIGPAVLLVATKFG-LLESKRTI *:.:*:*:::* * *:* : : ..**:*.*:: :.::* ::.:* Mb0458c|M.bovis_AF2122/97 KV-RGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPD Rv0450c|M.tuberculosis_H37Rv KV-RGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPD MLBr_02378|M.leprae_Br4923 KV-RGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPA MMAR_0771|M.marinum_M KV-RGWRRVGTVVVRWPLPVLAATLAVALVGLLALPGYRTNYNDRDYLPN Mflv_4418|M.gilvum_PYR-GCK SS-RGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPE Mvan_1936|M.vanbaalenii_PYR-1 SS-RGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPE MAV_2510|M.avium_104 RI-RGWRKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPT MSMEG_3496|M.smegmatis_MC2_155 RT-RGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQ TH_3260|M.thermoresistible__bu RV-RFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPA MUL_3688|M.ulcerans_Agy99 NRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPA MAB_2303|M.abscessus_ATCC_1997 KN-RTWRKVGTAIVRWPGPILAVTMIIALLGLGILPSYTVNYNDRYYIPA * **::*. :**** *:: : : ::*: **.: ..*. * *:* Mb0458c|M.bovis_AF2122/97 FIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIF Rv0450c|M.tuberculosis_H37Rv FIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIF MLBr_02378|M.leprae_Br4923 SIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIF MMAR_0771|M.marinum_M FIPANQGFTAAERHFSQARMKPDILMIQSDHDMRNPADFLVLDRLAKGIF Mflv_4418|M.gilvum_PYR-GCK DIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVF Mvan_1936|M.vanbaalenii_PYR-1 DVPANVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIF MAV_2510|M.avium_104 DLPANEGYAAADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVF MSMEG_3496|M.smegmatis_MC2_155 DLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVF TH_3260|M.thermoresistible__bu SFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVF MUL_3688|M.ulcerans_Agy99 SAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVI MAB_2303|M.abscessus_ATCC_1997 SLPSIQGFQASDRHFSKARMNPDILIVEADKDLRTPANMLVLDRIAKNVF *: * .:::** **::*::*::::::*:*..*::*:::::*: :: Mb0458c|M.bovis_AF2122/97 RVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDML Rv0450c|M.tuberculosis_H37Rv RVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDML MLBr_02378|M.leprae_Br4923 RVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLL MMAR_0771|M.marinum_M HVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDML Mflv_4418|M.gilvum_PYR-GCK RVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADML Mvan_1936|M.vanbaalenii_PYR-1 RVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADML MAV_2510|M.avium_104 RVPGIGRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADML MSMEG_3496|M.smegmatis_MC2_155 QVPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADML TH_3260|M.thermoresistible__bu QVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADML MUL_3688|M.ulcerans_Agy99 RTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMT MAB_2303|M.abscessus_ATCC_1997 RVEGINKVQSMTRPMGAPIDHSSVPFQVSMQSVSMTENMNYLKNSMSDML :. *: :* :*** * .:.*:::** * . . : :: *: Mb0458c|M.bovis_AF2122/97 KQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTE-EMKEITEELRDHVA Rv0450c|M.tuberculosis_H37Rv KQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTE-EMKEITEELRDHVA MLBr_02378|M.leprae_Br4923 RQAENMAETIASMRRMHQLMALLTENTHHILNDTV-EMQKTTSKLRDEIA MMAR_0771|M.marinum_M TQAEEMAKTIALMRRMYGLMTQLANNTHKMVGDTI-EMQQITKELRDHIA Mflv_4418|M.gilvum_PYR-GCK VQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTK-KTEIDIIEVRDNLA Mvan_1936|M.vanbaalenii_PYR-1 VQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTK-KTAVDIVEVRDYLA MAV_2510|M.avium_104 HQADMMQTTIDSMEKMQSITVQMSNDMHVMVQKMH-DMTIDINDLRNKMA MSMEG_3496|M.smegmatis_MC2_155 VMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMH-GMVEDIKELRDHIA TH_3260|M.thermoresistible__bu VQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMD-EMAAHVAEMRDSIS MUL_3688|M.ulcerans_Agy99 KMADEMQVLIDTTERMYAVMRELDTTTTDMARVTA-ETSTITDELRDHLA MAB_2303|M.abscessus_ATCC_1997 KMTDDMGSMIAIMERMYSLMKELTGVTHHMATVTTPDMIHVADEMRDNMA :: * : .* : : : .:*: :: Mb0458c|M.bovis_AF2122/97 DFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLG Rv0450c|M.tuberculosis_H37Rv DFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLG MLBr_02378|M.leprae_Br4923 NFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVG MMAR_0771|M.marinum_M NFDDFFRPIRSYFYWEKHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVV Mflv_4418|M.gilvum_PYR-GCK DFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIP Mvan_1936|M.vanbaalenii_PYR-1 NLDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIP MAV_2510|M.avium_104 DFEDFFRPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLP MSMEG_3496|M.smegmatis_MC2_155 DFDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMP TH_3260|M.thermoresistible__bu EFDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLP MUL_3688|M.ulcerans_Agy99 EFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTE MAB_2303|M.abscessus_ATCC_1997 NFDDFYRPLRNYLYWEKHCFDIPMCWSMRSLFDALDGIDKLTESMRGLLD :::** **:*.*:*** ** .:*:* ::**:**:***:: : : : : Mb0458c|M.bovis_AF2122/97 DLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDN Rv0450c|M.tuberculosis_H37Rv DLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDN MLBr_02378|M.leprae_Br4923 DIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDN MMAR_0771|M.marinum_M DIKELDRLMPQMIETFPPMIETMESMRLMMLTMHSTMSGLYDQMSEMSEN Mflv_4418|M.gilvum_PYR-GCK DLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSED Mvan_1936|M.vanbaalenii_PYR-1 DLERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSED MAV_2510|M.avium_104 IMDHLDTLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKN MSMEG_3496|M.smegmatis_MC2_155 DMDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMEN TH_3260|M.thermoresistible__bu HMHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQEN MUL_3688|M.ulcerans_Agy99 DIQRTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNT MAB_2303|M.abscessus_ATCC_1997 DVTNMDKLMPQVVEQLPPMIAITKNMRNTMLTMYSTMNGMIGQMDRMTDT : . * .*:: :*. : . : * : . .* . Mb0458c|M.bovis_AF2122/97 ATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILH Rv0450c|M.tuberculosis_H37Rv ATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILH MLBr_02378|M.leprae_Br4923 ANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILH MMAR_0771|M.marinum_M ANAMGKAFDAAKNDDSFYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILH Mflv_4418|M.gilvum_PYR-GCK ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISH Mvan_1936|M.vanbaalenii_PYR-1 ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAH MAV_2510|M.avium_104 SNAMGKAFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISH MSMEG_3496|M.smegmatis_MC2_155 QTAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISH TH_3260|M.thermoresistible__bu ANAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISH MUL_3688|M.ulcerans_Agy99 AIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITH MAB_2303|M.abscessus_ATCC_1997 ATVMGQAFDEAKNDDFFYLPPEAFDNEDFKKGVKLMMSPDGKAAQFIITH .**::** : *** ******.*.* :*: .:. ::*.**::.:*:* * Mb0458c|M.bovis_AF2122/97 RGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGA Rv0450c|M.tuberculosis_H37Rv RGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGA MLBr_02378|M.leprae_Br4923 RGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGA MMAR_0771|M.marinum_M RGDPQSAQGIASIDQIRTAAEESLKGTPLEDAKIYVAGTASVFKDISEGA Mflv_4418|M.gilvum_PYR-GCK EGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGA Mvan_1936|M.vanbaalenii_PYR-1 EGDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGA MAV_2510|M.avium_104 DGDPMTQEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGN MSMEG_3496|M.smegmatis_MC2_155 EGDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGA TH_3260|M.thermoresistible__bu QGDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGT MUL_3688|M.ulcerans_Agy99 QGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGE MAB_2303|M.abscessus_ATCC_1997 EGDYASNESLANTEVELKAAKEAIKGTPLDESKLYLGGTAPTYHDIGEMV ** : .: ** *.:* :.*. : :*:.***. ::*: : Mb0458c|M.bovis_AF2122/97 QWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLL Rv0450c|M.tuberculosis_H37Rv QWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLL MLBr_02378|M.leprae_Br4923 NWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLL MMAR_0771|M.marinum_M DWDLLIAGISSLCLIFIIMLILTRAFVAAAVIVGTVALSLGASFGMSVLL Mflv_4418|M.gilvum_PYR-GCK FYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLL Mvan_1936|M.vanbaalenii_PYR-1 NYDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLL MAV_2510|M.avium_104 NYDLLIAGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLI MSMEG_3496|M.smegmatis_MC2_155 NYDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLI TH_3260|M.thermoresistible__bu KYDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLI MUL_3688|M.ulcerans_Agy99 KYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLI MAB_2303|M.abscessus_ATCC_1997 KYDLMIAVIASLCLIFVIMLVITRSIVAAFTIVGTIAVSLGASFGLSVLL :**:** :::: ***:***::**..:*: .**** *:.****:***: Mb0458c|M.bovis_AF2122/97 WQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIR Rv0450c|M.tuberculosis_H37Rv WQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIR MLBr_02378|M.leprae_Br4923 WQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIR MMAR_0771|M.marinum_M WQHILNIDLHYMVLAMSVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIR Mflv_4418|M.gilvum_PYR-GCK WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIR Mvan_1936|M.vanbaalenii_PYR-1 WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIR MAV_2510|M.avium_104 WQHLIGIELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIR MSMEG_3496|M.smegmatis_MC2_155 WQHIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIR TH_3260|M.thermoresistible__bu WQYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIR MUL_3688|M.ulcerans_Agy99 WQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIR MAB_2303|M.abscessus_ATCC_1997 WEHILGLQLHWFVLPFTVIILLAVGSDYNLLLVSRFKEELHGGLNTAILR *: :. : :*::* .:::*:*****:*****:*:*:::*: .**:*.::* Mb0458c|M.bovis_AF2122/97 SMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVR Rv0450c|M.tuberculosis_H37Rv SMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVR MLBr_02378|M.leprae_Br4923 SMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVR MMAR_0771|M.marinum_M AMGGTGKVVTNAGLVFAFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVR Mflv_4418|M.gilvum_PYR-GCK AMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR Mvan_1936|M.vanbaalenii_PYR-1 SMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR MAV_2510|M.avium_104 SMGGTGSVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVR MSMEG_3496|M.smegmatis_MC2_155 SMGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIR TH_3260|M.thermoresistible__bu AMGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVR MUL_3688|M.ulcerans_Agy99 SMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVR MAB_2303|M.abscessus_ATCC_1997 GVGGSGSVATQAGLVFAFTMGSMITSDLIAIGQSGSAICLGLLFDTFIIR .:.*:* *.* *****..** : *:* .:.* *::: :***:**:::* Mb0458c|M.bovis_AF2122/97 SFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG Rv0450c|M.tuberculosis_H37Rv SFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG MLBr_02378|M.leprae_Br4923 SFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLP-PDRSLVYSD---- MMAR_0771|M.marinum_M AFMTPSIAALLGRWFWWPMRVRTRPARTPSSPTADPEPDRALAMSGER-- Mflv_4418|M.gilvum_PYR-GCK SFMTPAVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR-------- Mvan_1936|M.vanbaalenii_PYR-1 SFMTPAVAALLGRWFWWPQKVRSHASQRRLAALNH--------------- MAV_2510|M.avium_104 SLMTPSIAALLGKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA------ MSMEG_3496|M.smegmatis_MC2_155 SFMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV----- TH_3260|M.thermoresistible__bu SFMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---- MUL_3688|M.ulcerans_Agy99 TLLMPSIATLLGRWFWWPQVVHPRG-DNARPRVAAPTH------------ MAB_2303|M.abscessus_ATCC_1997 AFMTPAIAALMGRWFWWPMKVSKYATDPPPPPVPVESQTPPPPAPVPVGP ::: *::*:*:*:***** Mb0458c|M.bovis_AF2122/97 ------------------- Rv0450c|M.tuberculosis_H37Rv ------------------- MLBr_02378|M.leprae_Br4923 ------------------- MMAR_0771|M.marinum_M ------------------- Mflv_4418|M.gilvum_PYR-GCK ------------------- Mvan_1936|M.vanbaalenii_PYR-1 ------------------- MAV_2510|M.avium_104 ------------------- MSMEG_3496|M.smegmatis_MC2_155 ------------------- TH_3260|M.thermoresistible__bu ------------------- MUL_3688|M.ulcerans_Agy99 ------------------- MAB_2303|M.abscessus_ATCC_1997 SPGPAHDDAVTTEFPRPPV