For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_2303 (-)

annotation: putative membrane protein, MmpL
coordinates: 2353308 - 2356301
length: 997

MSTHSAPTHGAAQKPSRIARFIHTFSVPIILAWLVLTVIVNVVVPQLEEVGKEHSVSLASKDAPSYQAIK
RQGELFQQFKDDSMVMVLLENDTKFSTDMNDKAHTFYRELVKRLRADTKHVEYAQDFWGDRITAGGAQSV
DEKAAYVQLNLRGDQGTTEGKESVTAVQDNVAKLIDESKKNGTYPDGLKVFVTGQAALTMDMNDAGDKSM
LKMTGITFIVITIMLLFIYRSITTVLLILFMVFVELGAARGVVAILGNAEIIGLSTFAVNLLTSLAIAAG
TDYAIFLIGRYQELRAEGKERLESFYLTYHSVSHVILGSGLTIAGATFCLKFTRLPYFESLGVPCAIGML
VVVAASLTIGPAVLLVATKFGLLESKRTIKNRTWRKVGTAIVRWPGPILAVTMIIALLGLGILPSYTVNY
NDRYYIPASLPSIQGFQASDRHFSKARMNPDILIVEADKDLRTPANMLVLDRIAKNVFRVEGINKVQSMT
RPMGAPIDHSSVPFQVSMQSVSMTENMNYLKNSMSDMLKMTDDMGSMIAIMERMYSLMKELTGVTHHMAT
VTTPDMIHVADEMRDNMANFDDFYRPLRNYLYWEKHCFDIPMCWSMRSLFDALDGIDKLTESMRGLLDDV
TNMDKLMPQVVEQLPPMIAITKNMRNTMLTMYSTMNGMIGQMDRMTDTATVMGQAFDEAKNDDFFYLPPE
AFDNEDFKKGVKLMMSPDGKAAQFIITHEGDYASNESLANTEVELKAAKEAIKGTPLDESKLYLGGTAPT
YHDIGEMVKYDLMIAVIASLCLIFVIMLVITRSIVAAFTIVGTIAVSLGASFGLSVLLWEHILGLQLHWF
VLPFTVIILLAVGSDYNLLLVSRFKEELHGGLNTAILRGVGGSGSVATQAGLVFAFTMGSMITSDLIAIG
QSGSAICLGLLFDTFIIRAFMTPAIAALMGRWFWWPMKVSKYATDPPPPPVPVESQTPPPPAPVPVGPSP
GPAHDDAVTTEFPRPPV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2303--100% (997)putative membrane protein, MmpL
M. abscessus ATCC 19977MAB_2301-0.056.67% (990) putative membrane protein, mmpL
M. abscessus ATCC 19977MAB_1134c-0.056.55% (985) membrane protein MmpL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.056.15% (967) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_4418-0.054.79% (940) transport protein
M. tuberculosis H37RvRv0450cmmpL40.056.26% (967) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.056.68% (935) hypothetical protein MLBr_02378
M. marinum MMMAR_0771mmpL5_20.056.87% (953) transmembrane transport protein MmpL5_2
M. avium 104MAV_2510-0.055.42% (951) MmpL4 protein
M. smegmatis MC2 155MSMEG_3496-0.054.55% (977) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.052.55% (982) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_3688mmpL4_10.054.27% (949) transmembrane transport protein MmpL4_1
M. vanbaalenii PYR-1Mvan_1936-0.054.95% (939) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0458c|M.bovis_AF2122/97           MSTKFANDSNTNARPEKP------------------FIARMIHAFAVPII
Rv0450c|M.tuberculosis_H37Rv        MSTKFANDSNTNARPEKP------------------FIARMIHAFAVPII
MLBr_02378|M.leprae_Br4923          MTVKCANDLDT--HTKPP------------------FVARMIHRFAVPII
MMAR_0771|M.marinum_M               MTVKYANDPDTRTHTEKP------------------FLARMIHAFAVPII
Mflv_4418|M.gilvum_PYR-GCK          MADAGRSG-----------------------------IGRIIRVLAVPIV
Mvan_1936|M.vanbaalenii_PYR-1       MADAGRSG-----------------------------IGRIIHLLAVPIV
MAV_2510|M.avium_104                MSTTFDDTRTDAIPVV--KEPVREK------------IPRFIRAFAVPII
MSMEG_3496|M.smegmatis_MC2_155      MSNPSHDAPTDAMGVSGPKHARPGG------------IAKWIRVLAVPII
TH_3260|M.thermoresistible__bu      MTANPGHVRTDEAPTDRLDIKVSTHGPS--------FISTWIRRLSLPII
MUL_3688|M.ulcerans_Agy99           MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPII
MAB_2303|M.abscessus_ATCC_1997      MSTHSAPTHGAAQKPSR--------------------IARFIHTFSVPII
                                    *:                                   :   *: :::**:

Mb0458c|M.bovis_AF2122/97           LGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGD
Rv0450c|M.tuberculosis_H37Rv        LGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGD
MLBr_02378|M.leprae_Br4923          LVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGN
MMAR_0771|M.marinum_M               LAWVAVCVALSVFIPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGN
Mflv_4418|M.gilvum_PYR-GCK          LGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFD
Mvan_1936|M.vanbaalenii_PYR-1       LGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFD
MAV_2510|M.avium_104                IGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYK
MSMEG_3496|M.smegmatis_MC2_155      LVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFK
TH_3260|M.thermoresistible__bu      VGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGS
MUL_3688|M.ulcerans_Agy99           LGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFREFD
MAB_2303|M.abscessus_ATCC_1997      LAWLVLTVIVNVVVPQLEEVGKEHSVSLASKDAPSYQAIKRQGELFQQFK
                                    : *: : .  .  :*.*: *.: ::. ::. :* *  :  : *  * : .

Mb0458c|M.bovis_AF2122/97           SDSFAMVIIEGNQPLG----DAAHKYYDGLVAQLRADKKHVQSVQDLWGD
Rv0450c|M.tuberculosis_H37Rv        SDSFAMVIIEGNQPLG----DAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923          SDSVIMIVLEGDKPLG----DDAHRFYDGLIRKLRAD-KHVQSVQDFWGD
MMAR_0771|M.marinum_M               SDSQAMIVLEGKDALG----DDAHKYYDVLIRKLRADPRHVQSVQDFWGD
Mflv_4418|M.gilvum_PYR-GCK          SDSSAMVVLEGEQPLG----DAAHRYYDQLIDELEADTANVQHIADFWGD
Mvan_1936|M.vanbaalenii_PYR-1       SDSSAMVVLEGEQPLG----DAAHRYYDELIGKLEADTANVQHVADFWGD
MAV_2510|M.avium_104                SNSSVMIVLEGQQPLG----ADAHAYYDEIVRRLNADTKHVEHVQDMWSD
MSMEG_3496|M.smegmatis_MC2_155      SNSSVMIVLEGEQPLG----DEAHKYYDEIVDKLEADPAHVEHVQDFWGD
TH_3260|M.thermoresistible__bu      SDSQVMIVLEGEEPLG----ADARAFYDELVKRLEADDAHVENVQDLWSD
MUL_3688|M.ulcerans_Agy99           SNSTVMIVLEGQHKLG----DDAHQYYDSLIRQLRQDPEHIQHIQDFWGD
MAB_2303|M.abscessus_ATCC_1997      DDSMVMVLLENDTKFSTDMNDKAHTFYRELVKRLRADTKHVEYAQDFWGD
                                    .:*  *:::*..  :.      *: :*  :: .*. *  :::   *:*.*

Mb0458c|M.bovis_AF2122/97           PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST------
Rv0450c|M.tuberculosis_H37Rv        PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST------
MLBr_02378|M.leprae_Br4923          PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT------
MMAR_0771|M.marinum_M               PLTAAGAQSNDGKAAYVQLNLAGNQGEPLANESVEAVRKIVKET------
Mflv_4418|M.gilvum_PYR-GCK          PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT------
Mvan_1936|M.vanbaalenii_PYR-1       PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQT------
MAV_2510|M.avium_104                PLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSV------
MSMEG_3496|M.smegmatis_MC2_155      PLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESV------
TH_3260|M.thermoresistible__bu      PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE---
MUL_3688|M.ulcerans_Agy99           RLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT------
MAB_2303|M.abscessus_ATCC_1997      RITAGGAQSVDEKAAYVQLNLRGDQGTTEGKESVTAVQDNVAKLIDESKK
                                     :*. *.** *  ::** :   *:**   .:*:: :*:. :         

Mb0458c|M.bovis_AF2122/97           --PAPPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYR
Rv0450c|M.tuberculosis_H37Rv        --PAPPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYR
MLBr_02378|M.leprae_Br4923          --PAPPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYR
MMAR_0771|M.marinum_M               --PAPPGVTTYVTGAAALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYR
Mflv_4418|M.gilvum_PYR-GCK          --PAPPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFR
Mvan_1936|M.vanbaalenii_PYR-1       --PAPPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFR
MAV_2510|M.avium_104                --QAPNGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYR
MSMEG_3496|M.smegmatis_MC2_155      --PAPPGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYR
TH_3260|M.thermoresistible__bu      --MAPEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYR
MUL_3688|M.ulcerans_Agy99           --HEPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYR
MAB_2303|M.abscessus_ATCC_1997      NGTYPDGLKVFVTGQAALTMDMNDAGDKSMLKMTGITFIVITIMLLFIYR
                                        * *: .:*** :.:  * :  .: *:  :   :. .*   **:::*

Mb0458c|M.bovis_AF2122/97           SIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAG
Rv0450c|M.tuberculosis_H37Rv        SIITVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAG
MLBr_02378|M.leprae_Br4923          SFITVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAG
MMAR_0771|M.marinum_M               SVITVVVLLLTVGVELTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAG
Mflv_4418|M.gilvum_PYR-GCK          SVATMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAG
Mvan_1936|M.vanbaalenii_PYR-1       SVATMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAG
MAV_2510|M.avium_104                SVITVLLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAA
MSMEG_3496|M.smegmatis_MC2_155      SIVTVILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAA
TH_3260|M.thermoresistible__bu      SVITVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIA
MUL_3688|M.ulcerans_Agy99           SIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAG
MAB_2303|M.abscessus_ATCC_1997      SITTVLLILFMVFVELGAARGVVAILGNAEIIGLSTFAVNLLTSLAIAAG
                                    *. * :: *. .      :**::*.*.    :**:.**..:*. :.** .

Mb0458c|M.bovis_AF2122/97           TDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCL
Rv0450c|M.tuberculosis_H37Rv        TDYGIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCL
MLBr_02378|M.leprae_Br4923          TDYGIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCL
MMAR_0771|M.marinum_M               TDYGIFIFGRYQEARQAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCL
Mflv_4418|M.gilvum_PYR-GCK          TDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCL
Mvan_1936|M.vanbaalenii_PYR-1       TDYAIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCL
MAV_2510|M.avium_104                TDYAIFLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCL
MSMEG_3496|M.smegmatis_MC2_155      TDYAIFLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCL
TH_3260|M.thermoresistible__bu      VDYAIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCL
MUL_3688|M.ulcerans_Agy99           TDYGIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCL
MAB_2303|M.abscessus_ATCC_1997      TDYAIFLIGRYQELRAEGKERLESFYLTYHSVSHVILGSGLTIAGATFCL
                                    .**.**  ***** *  . .:  :::  : ..  *: .**:**:**  **

Mb0458c|M.bovis_AF2122/97           SFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLL
Rv0450c|M.tuberculosis_H37Rv        SFARMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLL
MLBr_02378|M.leprae_Br4923          SFARMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLI
MMAR_0771|M.marinum_M               KFARMPYFETLGIPCAVGMLVAVMVALTLGPAVLTVGSRFG-LFDPKRLI
Mflv_4418|M.gilvum_PYR-GCK          SFTRLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAI
Mvan_1936|M.vanbaalenii_PYR-1       SFTRLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAI
MAV_2510|M.avium_104                HFTNLPYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQ
MSMEG_3496|M.smegmatis_MC2_155      HFTRMPYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAM
TH_3260|M.thermoresistible__bu      SFTRLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAA
MUL_3688|M.ulcerans_Agy99           SFARLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-PFESKRAA
MAB_2303|M.abscessus_ATCC_1997      KFTRLPYFESLGVPCAIGMLVVVAASLTIGPAVLLVATKFG-LLESKRTI
                                     *:.:*:*:::* * *:*  : : ..**:*.*:: :.::*   ::.:*  

Mb0458c|M.bovis_AF2122/97           KV-RGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPD
Rv0450c|M.tuberculosis_H37Rv        KV-RGWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPD
MLBr_02378|M.leprae_Br4923          KV-RGWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPA
MMAR_0771|M.marinum_M               KV-RGWRRVGTVVVRWPLPVLAATLAVALVGLLALPGYRTNYNDRDYLPN
Mflv_4418|M.gilvum_PYR-GCK          SS-RGWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPE
Mvan_1936|M.vanbaalenii_PYR-1       SS-RGWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPE
MAV_2510|M.avium_104                RI-RGWRKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPT
MSMEG_3496|M.smegmatis_MC2_155      RT-RGWRKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQ
TH_3260|M.thermoresistible__bu      RV-RFWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPA
MUL_3688|M.ulcerans_Agy99           NRGRLWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPA
MAB_2303|M.abscessus_ATCC_1997      KN-RTWRKVGTAIVRWPGPILAVTMIIALLGLGILPSYTVNYNDRYYIPA
                                       * **::*. :**** *::  :  : ::*:  **.: ..*. * *:* 

Mb0458c|M.bovis_AF2122/97           FIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIF
Rv0450c|M.tuberculosis_H37Rv        FIPANQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIF
MLBr_02378|M.leprae_Br4923          SIPANQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIF
MMAR_0771|M.marinum_M               FIPANQGFTAAERHFSQARMKPDILMIQSDHDMRNPADFLVLDRLAKGIF
Mflv_4418|M.gilvum_PYR-GCK          DIPANVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVF
Mvan_1936|M.vanbaalenii_PYR-1       DVPANVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIF
MAV_2510|M.avium_104                DLPANEGYAAADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVF
MSMEG_3496|M.smegmatis_MC2_155      DLPANTGYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVF
TH_3260|M.thermoresistible__bu      SFPSNAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVF
MUL_3688|M.ulcerans_Agy99           SAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVI
MAB_2303|M.abscessus_ATCC_1997      SLPSIQGFQASDRHFSKARMNPDILIVEADKDLRTPANMLVLDRIAKNVF
                                      *:  *  .:::**  **::*::*::::::*:*..*::*:::::*: ::

Mb0458c|M.bovis_AF2122/97           RVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDML
Rv0450c|M.tuberculosis_H37Rv        RVPGISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDML
MLBr_02378|M.leprae_Br4923          RVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLL
MMAR_0771|M.marinum_M               HVPGISRVQAITRPDGTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDML
Mflv_4418|M.gilvum_PYR-GCK          RVPGVARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADML
Mvan_1936|M.vanbaalenii_PYR-1       RVPGVARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADML
MAV_2510|M.avium_104                RVPGIGRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADML
MSMEG_3496|M.smegmatis_MC2_155      QVPGISRVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADML
TH_3260|M.thermoresistible__bu      QVEGISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADML
MUL_3688|M.ulcerans_Agy99           RTVGIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMT
MAB_2303|M.abscessus_ATCC_1997      RVEGINKVQSMTRPMGAPIDHSSVPFQVSMQSVSMTENMNYLKNSMSDML
                                    :. *:  :* :*** * .:.*:::**  *  .     .  : ::   *: 

Mb0458c|M.bovis_AF2122/97           KQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTE-EMKEITEELRDHVA
Rv0450c|M.tuberculosis_H37Rv        KQADEMATTIAVLTRMHSLMAEMASTTHRMVGDTE-EMKEITEELRDHVA
MLBr_02378|M.leprae_Br4923          RQAENMAETIASMRRMHQLMALLTENTHHILNDTV-EMQKTTSKLRDEIA
MMAR_0771|M.marinum_M               TQAEEMAKTIALMRRMYGLMTQLANNTHKMVGDTI-EMQQITKELRDHIA
Mflv_4418|M.gilvum_PYR-GCK          VQADAMQTNVDTMTRMQSLMGQMSATTHEMVLKTK-KTEIDIIEVRDNLA
Mvan_1936|M.vanbaalenii_PYR-1       VQADAMQTNVDTMTKMQSLMTQMSAATHDMVTKTK-KTAVDIVEVRDYLA
MAV_2510|M.avium_104                HQADMMQTTIDSMEKMQSITVQMSNDMHVMVQKMH-DMTIDINDLRNKMA
MSMEG_3496|M.smegmatis_MC2_155      VMADEMQKSVDTMEEMLKITREMSDTTHSMVGKMH-GMVEDIKELRDHIA
TH_3260|M.thermoresistible__bu      VQADEMQLMIDTMDKMIALMEEMVETTDNMVRDMD-EMAAHVAEMRDSIS
MUL_3688|M.ulcerans_Agy99           KMADEMQVLIDTTERMYAVMRELDTTTTDMARVTA-ETSTITDELRDHLA
MAB_2303|M.abscessus_ATCC_1997      KMTDDMGSMIAIMERMYSLMKELTGVTHHMATVTTPDMIHVADEMRDNMA
                                      :: *   :    .*  :   :      :             .:*: ::

Mb0458c|M.bovis_AF2122/97           DFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLG
Rv0450c|M.tuberculosis_H37Rv        DFDDFWRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLG
MLBr_02378|M.leprae_Br4923          NFDDFWRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVG
MMAR_0771|M.marinum_M               NFDDFFRPIRSYFYWEKHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVV
Mflv_4418|M.gilvum_PYR-GCK          DFDDFFRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIP
Mvan_1936|M.vanbaalenii_PYR-1       NLDDFVRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIP
MAV_2510|M.avium_104                DFEDFFRPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLP
MSMEG_3496|M.smegmatis_MC2_155      DFDDFLRPIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMP
TH_3260|M.thermoresistible__bu      EFDDFFRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLP
MUL_3688|M.ulcerans_Agy99           EFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTE
MAB_2303|M.abscessus_ATCC_1997      NFDDFYRPLRNYLYWEKHCFDIPMCWSMRSLFDALDGIDKLTESMRGLLD
                                    :::** **:*.*:*** ** .:*:* ::**:**:***:: : : :  :  

Mb0458c|M.bovis_AF2122/97           DLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDN
Rv0450c|M.tuberculosis_H37Rv        DLREMDRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDN
MLBr_02378|M.leprae_Br4923          DIKNMDLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDN
MMAR_0771|M.marinum_M               DIKELDRLMPQMIETFPPMIETMESMRLMMLTMHSTMSGLYDQMSEMSEN
Mflv_4418|M.gilvum_PYR-GCK          DLERLDELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSED
Mvan_1936|M.vanbaalenii_PYR-1       DLERLDALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSED
MAV_2510|M.avium_104                IMDHLDTLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKN
MSMEG_3496|M.smegmatis_MC2_155      DMDRLDELMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMEN
TH_3260|M.thermoresistible__bu      HMHRLNDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQEN
MUL_3688|M.ulcerans_Agy99           DIQRTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNT
MAB_2303|M.abscessus_ATCC_1997      DVTNMDKLMPQVVEQLPPMIAITKNMRNTMLTMYSTMNGMIGQMDRMTDT
                                     : .   * .*::  :*. :   .  :   *    :  .  .*     . 

Mb0458c|M.bovis_AF2122/97           ATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILH
Rv0450c|M.tuberculosis_H37Rv        ATAMGKAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILH
MLBr_02378|M.leprae_Br4923          ANTMGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILH
MMAR_0771|M.marinum_M               ANAMGKAFDAAKNDDSFYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILH
Mflv_4418|M.gilvum_PYR-GCK          ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISH
Mvan_1936|M.vanbaalenii_PYR-1       ADAMGEAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAH
MAV_2510|M.avium_104                SNAMGKAFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISH
MSMEG_3496|M.smegmatis_MC2_155      QTAMGQAFDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISH
TH_3260|M.thermoresistible__bu      ANAMGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISH
MUL_3688|M.ulcerans_Agy99           AIVMGQSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITH
MAB_2303|M.abscessus_ATCC_1997      ATVMGQAFDEAKNDDFFYLPPEAFDNEDFKKGVKLMMSPDGKAAQFIITH
                                      .**::** : *** ******.*.* :*: .:. ::*.**::.:*:* *

Mb0458c|M.bovis_AF2122/97           RGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGA
Rv0450c|M.tuberculosis_H37Rv        RGDPQSPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGA
MLBr_02378|M.leprae_Br4923          RGDPASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGA
MMAR_0771|M.marinum_M               RGDPQSAQGIASIDQIRTAAEESLKGTPLEDAKIYVAGTASVFKDISEGA
Mflv_4418|M.gilvum_PYR-GCK          EGDPATVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGA
Mvan_1936|M.vanbaalenii_PYR-1       EGDPATVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGA
MAV_2510|M.avium_104                DGDPMTQEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGN
MSMEG_3496|M.smegmatis_MC2_155      EGDPMSPEGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGA
TH_3260|M.thermoresistible__bu      QGDPMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGT
MUL_3688|M.ulcerans_Agy99           QGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGE
MAB_2303|M.abscessus_ATCC_1997      EGDYASNESLANTEVELKAAKEAIKGTPLDESKLYLGGTAPTYHDIGEMV
                                     **  :  .:        ** *.:* :.*. : :*:.***. ::*: :  

Mb0458c|M.bovis_AF2122/97           QWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLL
Rv0450c|M.tuberculosis_H37Rv        QWDLLIAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLL
MLBr_02378|M.leprae_Br4923          NWDLVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLL
MMAR_0771|M.marinum_M               DWDLLIAGISSLCLIFIIMLILTRAFVAAAVIVGTVALSLGASFGMSVLL
Mflv_4418|M.gilvum_PYR-GCK          FYDLLIAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLL
Mvan_1936|M.vanbaalenii_PYR-1       NYDLLIAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLL
MAV_2510|M.avium_104                NYDLLIAGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLI
MSMEG_3496|M.smegmatis_MC2_155      NYDLIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLI
TH_3260|M.thermoresistible__bu      KYDLIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLI
MUL_3688|M.ulcerans_Agy99           KYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLI
MAB_2303|M.abscessus_ATCC_1997      KYDLMIAVIASLCLIFVIMLVITRSIVAAFTIVGTIAVSLGASFGLSVLL
                                     :**:** :::: ***:***::**..:*: .****   *:.****:***:

Mb0458c|M.bovis_AF2122/97           WQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIR
Rv0450c|M.tuberculosis_H37Rv        WQHILAIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIR
MLBr_02378|M.leprae_Br4923          WQHILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIR
MMAR_0771|M.marinum_M               WQHILNIDLHYMVLAMSVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIR
Mflv_4418|M.gilvum_PYR-GCK          WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIR
Mvan_1936|M.vanbaalenii_PYR-1       WQHIIGLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIR
MAV_2510|M.avium_104                WQHLIGIELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIR
MSMEG_3496|M.smegmatis_MC2_155      WQHIIGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIR
TH_3260|M.thermoresistible__bu      WQYIVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIR
MUL_3688|M.ulcerans_Agy99           WQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIR
MAB_2303|M.abscessus_ATCC_1997      WEHILGLQLHWFVLPFTVIILLAVGSDYNLLLVSRFKEELHGGLNTAILR
                                    *: :. : :*::* .:::*:*****:*****:*:*:::*: .**:*.::*

Mb0458c|M.bovis_AF2122/97           SMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVR
Rv0450c|M.tuberculosis_H37Rv        SMGGTGKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVR
MLBr_02378|M.leprae_Br4923          SMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVR
MMAR_0771|M.marinum_M               AMGGTGKVVTNAGLVFAFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVR
Mflv_4418|M.gilvum_PYR-GCK          AMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR
Mvan_1936|M.vanbaalenii_PYR-1       SMAGTGSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVR
MAV_2510|M.avium_104                SMGGTGSVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVR
MSMEG_3496|M.smegmatis_MC2_155      SMGGTGSVVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIR
TH_3260|M.thermoresistible__bu      AMGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVR
MUL_3688|M.ulcerans_Agy99           SMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVR
MAB_2303|M.abscessus_ATCC_1997      GVGGSGSVATQAGLVFAFTMGSMITSDLIAIGQSGSAICLGLLFDTFIIR
                                    .:.*:* *.* *****..**  :  *:* .:.* *::: :***:**:::*

Mb0458c|M.bovis_AF2122/97           SFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG
Rv0450c|M.tuberculosis_H37Rv        SFMTPSIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG
MLBr_02378|M.leprae_Br4923          SFMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVGLP-PDRSLVYSD----
MMAR_0771|M.marinum_M               AFMTPSIAALLGRWFWWPMRVRTRPARTPSSPTADPEPDRALAMSGER--
Mflv_4418|M.gilvum_PYR-GCK          SFMTPAVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR--------
Mvan_1936|M.vanbaalenii_PYR-1       SFMTPAVAALLGRWFWWPQKVRSHASQRRLAALNH---------------
MAV_2510|M.avium_104                SLMTPSIAALLGKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA------
MSMEG_3496|M.smegmatis_MC2_155      SFMTPSIAALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV-----
TH_3260|M.thermoresistible__bu      SFMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV----
MUL_3688|M.ulcerans_Agy99           TLLMPSIATLLGRWFWWPQVVHPRG-DNARPRVAAPTH------------
MAB_2303|M.abscessus_ATCC_1997      AFMTPAIAALMGRWFWWPMKVSKYATDPPPPPVPVESQTPPPPAPVPVGP
                                    ::: *::*:*:*:*****                                

Mb0458c|M.bovis_AF2122/97           -------------------
Rv0450c|M.tuberculosis_H37Rv        -------------------
MLBr_02378|M.leprae_Br4923          -------------------
MMAR_0771|M.marinum_M               -------------------
Mflv_4418|M.gilvum_PYR-GCK          -------------------
Mvan_1936|M.vanbaalenii_PYR-1       -------------------
MAV_2510|M.avium_104                -------------------
MSMEG_3496|M.smegmatis_MC2_155      -------------------
TH_3260|M.thermoresistible__bu      -------------------
MUL_3688|M.ulcerans_Agy99           -------------------
MAB_2303|M.abscessus_ATCC_1997      SPGPAHDDAVTTEFPRPPV