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M. abscessus ATCC 19977 MAB_4768c (-)

annotation: putative membrane protein, MmpL
coordinates: 4879346 - 4882177
length: 943

SEQSKHSVKRPLIPRMVRVLAVPIVVFWAIVAVTTNTFVPHVEDVAEELAGPMIPHYAPSQRAMLHIGEK
FQESTSTSLTMLVLEADRPLDGSDHQYYDDLVRRLKSDTEHVQYVMDTWGKPITAAGAQSLDGKSAFVLL
RLAGDIGQTQANKSVEAIKETIDKDTPPRGLKVYVSGAAPLASDTLSVANSSLNNITIVTIFLIIFMLLM
VYRSVTTMLVPLFGVLVEMLVARGVVATLGHFGYIELSSFAVNIVIALTLGAGTDYGIFLLGRYHEARNA
GLDREDAFYSAYRGVSHVIIGSGLTIAGAGLCLSFARLNYFHTMGPAVAIAMLLTIAAALTLGPALLHLG
SLFGLFDPKRRVKARLYRRIGASVVRWPKPILVASAAAVLVGAVFVPTYQVNYDDRAYQPPDAPAKQGFA
AADRHFPPSKLFTEMLMVESDHDMRNSADFISLDRVSKSLVRLPGVAMVQSITRPMGRALEHASLPYLFT
TQGSGNGQQLPFTKAQNANTDRQAQIMAHSVAVLRQTTDLTQQLADEMHNTVVTMEDMQQVTQDMNEKVS
NLDDFMRPLRNYFYWEPHCFDIPVCQSFRSLFDMLDSIDKLAADIKDAVGSLEVVDRLLPQMVALLKLTA
NDQEALQALIVNTYGQTNLQATATDQTFDDMINVGNDFDASRSDDFFYIPHEAFDNEDIKTGMTLMMSPD
GKAARFIVTHMGNAMGPEGIEHVNDFPDAITTALKETSLAGAQVYIGGAGSNNKDIKQYAASDLLIAAIA
AFTLIFLIMMVITRSLVAPFVIIGTVAFSFAGAFGLSVLIWQHLVGLPLHWLILPLTFIILVAVGSDYNL
LLIARLKEETDAGLNTGLIRALGSTGGVVTSAGLVFAFTMLAMLASDLRTIGQVGTTVCIGLLLDTLIVR
SFIVPALVRLLGTWFWWPTRVLARPRREPVRS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4768c--100% (943)putative membrane protein, MmpL
M. abscessus ATCC 19977MAB_3562c-0.080.24% (931) MmpL family protein
M. abscessus ATCC 19977MAB_2037-0.056.55% (932) putative membrane protein MmpL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.049.09% (931) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_4418-0.048.91% (918) transport protein
M. tuberculosis H37RvRv0450cmmpL40.049.19% (931) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.047.79% (927) hypothetical protein MLBr_02378
M. marinum MMMAR_0771mmpL5_20.048.87% (931) transmembrane transport protein MmpL5_2
M. avium 104MAV_3863-0.049.20% (933) MmpL4 protein
M. smegmatis MC2 155MSMEG_0185-0.075.16% (938) MmpL6 protein
M. thermoresistible (build 8)TH_3260-0.045.34% (933) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_3688mmpL4_10.048.88% (937) transmembrane transport protein MmpL4_1
M. vanbaalenii PYR-1Mvan_1936-0.048.70% (920) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0458c|M.bovis_AF2122/97           ---MSTKFANDSN------------------TNARPEKPFIARMIHAFAV
Rv0450c|M.tuberculosis_H37Rv        ---MSTKFANDSN------------------TNARPEKPFIARMIHAFAV
MMAR_0771|M.marinum_M               ---MTVKYANDPD------------------TRTHTEKPFLARMIHAFAV
MLBr_02378|M.leprae_Br4923          ---MTVKCANDLD------------------THTKP--PFVARMIHRFAV
Mflv_4418|M.gilvum_PYR-GCK          --------------------------------MADAGRSGIGRIIRVLAV
Mvan_1936|M.vanbaalenii_PYR-1       --------------------------------MADAGRSGIGRIIHLLAV
TH_3260|M.thermoresistible__bu      ---MTANPGHVRTDEAPTDRLDI--------KVSTHGPSFISTWIRRLSL
MAV_3863|M.avium_104                ----------------------M--------TTDQATRSVVAQTIRRLSV
MUL_3688|M.ulcerans_Agy99           ---MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAV
MAB_4768c|M.abscessus_ATCC_199      ---MSEQ------------------------SKHSVKRPLIPRMVRVLAV
MSMEG_0185|M.smegmatis_MC2_155      MPGQVRM------------------------SAHRAGRPFFARTVRVLAV
                                                                          . .   :: :::

Mb0458c|M.bovis_AF2122/97           PIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFK
Rv0450c|M.tuberculosis_H37Rv        PIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFK
MMAR_0771|M.marinum_M               PIILAWVAVCVALSVFIPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFN
MLBr_02378|M.leprae_Br4923          PIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFN
Mflv_4418|M.gilvum_PYR-GCK          PIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFE
Mvan_1936|M.vanbaalenii_PYR-1       PIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFD
TH_3260|M.thermoresistible__bu      PIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFD
MAV_3863|M.avium_104                PILLVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAMQHIGKVFH
MUL_3688|M.ulcerans_Agy99           PIILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFR
MAB_4768c|M.abscessus_ATCC_199      PIVVFWAIVAVTTNTFVPHVEDVAEELAGPMIPHYAPSQRAMLHIGEKFQ
MSMEG_0185|M.smegmatis_MC2_155      PIIVFWGLLAVTTNTFIPQVEHVADELAGPMIPNYAPSQVALLHIGEKFQ
                                    **:: *  : .  .  :* :* *..     : .  ***  :: ::*  * 

Mb0458c|M.bovis_AF2122/97           EGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDP
Rv0450c|M.tuberculosis_H37Rv        EGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDP
MMAR_0771|M.marinum_M               EGNSDSQAMIVLEGKDALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDP
MLBr_02378|M.leprae_Br4923          EGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDP
Mflv_4418|M.gilvum_PYR-GCK          EFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDP
Mvan_1936|M.vanbaalenii_PYR-1       EFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDP
TH_3260|M.thermoresistible__bu      EGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDP
MAV_3863|M.avium_104                EYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEHVQNFWGDP
MUL_3688|M.ulcerans_Agy99           EFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDR
MAB_4768c|M.abscessus_ATCC_199      ESTSTSLTMLVLEADRPLDGSDHQYYDDLVRRLKSDTEHVQYVMDTWGKP
MSMEG_0185|M.smegmatis_MC2_155      ESDSTNLTMLVFEADRPLDDGDHRYYDDLVRRLQADTEHVQYVMDLWGKP
                                    *  * .  *:::*..  *.   : :** *: .*. *  ::: : : *.. 

Mb0458c|M.bovis_AF2122/97           LTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---PAPP
Rv0450c|M.tuberculosis_H37Rv        LTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---PAPP
MMAR_0771|M.marinum_M               LTAAGAQSNDGKAAYVQLNLAGNQGEPLANESVEAVRKIVKET---PAPP
MLBr_02378|M.leprae_Br4923          LTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---PAPP
Mflv_4418|M.gilvum_PYR-GCK          LTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT---PAPP
Mvan_1936|M.vanbaalenii_PYR-1       LTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQT---PAPP
TH_3260|M.thermoresistible__bu      LTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPE
MAV_3863|M.avium_104                LTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIVEHT---PPPP
MUL_3688|M.ulcerans_Agy99           LTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT---HEPA
MAB_4768c|M.abscessus_ATCC_199      ITAAGAQSLDGKSAFVLLRLAGDIGQTQANKSVEAIKETIDKD---TPPR
MSMEG_0185|M.smegmatis_MC2_155      ITAAGAQSVDGKASFVLLRLAGNIGQLEANESVDAVRDIIADD---APPQ
                                    :**.* ** ***:::* : * *: *   *:::: :::. :        * 

Mb0458c|M.bovis_AF2122/97           GIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVV
Rv0450c|M.tuberculosis_H37Rv        GIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVV
MMAR_0771|M.marinum_M               GVTTYVTGAAALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYRSVITVV
MLBr_02378|M.leprae_Br4923          GITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVI
Mflv_4418|M.gilvum_PYR-GCK          GIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMV
Mvan_1936|M.vanbaalenii_PYR-1       GLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMV
TH_3260|M.thermoresistible__bu      GVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVL
MAV_3863|M.avium_104                GVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVYRS-VTAV
MUL_3688|M.ulcerans_Agy99           GVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTV
MAB_4768c|M.abscessus_ATCC_199      GLKVYVSGAAPLASDTLSVANSSLNNITIVTIFLIIFMLLMVYRSVTTML
MSMEG_0185|M.smegmatis_MC2_155      GLKVYVSGAAPLASDTLSTANSSLNNITIFTIILIVVMLLLVYRSAACLL
                                    *: .:*:* :.:  *    .. .:  :   :.  *   ** *:**    :

Mb0458c|M.bovis_AF2122/97           LLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIF
Rv0450c|M.tuberculosis_H37Rv        LLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIF
MMAR_0771|M.marinum_M               VLLLTVGVELTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIF
MLBr_02378|M.leprae_Br4923          LLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIF
Mflv_4418|M.gilvum_PYR-GCK          LILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIF
Mvan_1936|M.vanbaalenii_PYR-1       LILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIF
TH_3260|M.thermoresistible__bu      IALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIF
MAV_3863|M.avium_104                FVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAAGTDYAIF
MUL_3688|M.ulcerans_Agy99           IQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIF
MAB_4768c|M.abscessus_ATCC_199      VPLFGVLVEMLVARGVVATLGHFGYIELSSFAVNIVIALTLGAGTDYGIF
MSMEG_0185|M.smegmatis_MC2_155      VPLPAVLIEMLVAKGVIATLGHFGLIPLSSFAVNVVVALTLGAGTDYGIF
                                    . *  .      ::*::* *.    : *:::*..::  :.:. ..**.**

Mb0458c|M.bovis_AF2122/97           IIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMP
Rv0450c|M.tuberculosis_H37Rv        IIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMP
MMAR_0771|M.marinum_M               IFGRYQEARQAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCLKFARMP
MLBr_02378|M.leprae_Br4923          ITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMP
Mflv_4418|M.gilvum_PYR-GCK          AIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLP
Mvan_1936|M.vanbaalenii_PYR-1       AIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLP
TH_3260|M.thermoresistible__bu      LIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLP
MAV_3863|M.avium_104                FVGRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLCLRFTRLN
MUL_3688|M.ulcerans_Agy99           LVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLP
MAB_4768c|M.abscessus_ATCC_199      LLGRYHEARNAGLDREDAFYSAYRGVSHVIIGSGLTIAGAGLCLSFARLN
MSMEG_0185|M.smegmatis_MC2_155      LLGRYHEARQSGESREDAYFTAYRSVAPIIIGSGLTIAGACFCLSLARLD
                                      ***:***  . .:  *:.: : ..  :::.****::**  ** ::*: 

Mb0458c|M.bovis_AF2122/97           YFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFGLFDPKRLLKV-RGWR
Rv0450c|M.tuberculosis_H37Rv        YFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFGLFDPKRLLKV-RGWR
MMAR_0771|M.marinum_M               YFETLGIPCAVGMLVAVMVALTLGPAVLTVGSRFGLFDPKRLIKV-RGWR
MLBr_02378|M.leprae_Br4923          YFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFGLFEPKRLIKV-RGWR
Mflv_4418|M.gilvum_PYR-GCK          YFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFGLFDPKRAISS-RGWR
Mvan_1936|M.vanbaalenii_PYR-1       YFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFGLFDPKRAISS-RGWR
TH_3260|M.thermoresistible__bu      YFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFGLLEPKRAARV-RFWR
MAV_3863|M.avium_104                YFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFGLFDPKRQMAT-RGWR
MUL_3688|M.ulcerans_Agy99           WFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGRLWR
MAB_4768c|M.abscessus_ATCC_199      YFHTMGPAVAIAMLLTIAAALTLGPALLHLGSLFGLFDPKRRVKA-RLYR
MSMEG_0185|M.smegmatis_MC2_155      YFHTMGPAVAISMLFTIAAALTLAPALLTLGSLLALFDPKRPTRG-HLYR
                                    :*.::* . *:.  . : ..*:: **:: :.: :  ::.**     : :*

Mb0458c|M.bovis_AF2122/97           RVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQG
Rv0450c|M.tuberculosis_H37Rv        RVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQG
MMAR_0771|M.marinum_M               RVGTVVVRWPLPVLAATLAVALVGLLALPGYRTNYNDRDYLPNFIPANQG
MLBr_02378|M.leprae_Br4923          RIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQG
Mflv_4418|M.gilvum_PYR-GCK          RIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVG
Mvan_1936|M.vanbaalenii_PYR-1       RIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVG
TH_3260|M.thermoresistible__bu      KVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAG
MAV_3863|M.avium_104                RIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPASAPANTG
MUL_3688|M.ulcerans_Agy99           RVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLG
MAB_4768c|M.abscessus_ATCC_199      RIGASVVRWPKPILVASAAAVLVGAVFVPTYQVNYDDRAYQPPDAPAKQG
MSMEG_0185|M.smegmatis_MC2_155      RIGTSVVRWPKPIFVASAAVVMVGAVFVPSYRVNYDDRAYQPVDAAANLG
                                    ::*. :**** *::  : . .:** : :* ::..*. * * *   .:: *

Mb0458c|M.bovis_AF2122/97           YAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISR
Rv0450c|M.tuberculosis_H37Rv        YAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISR
MMAR_0771|M.marinum_M               FTAAERHFSQARMKPDILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISR
MLBr_02378|M.leprae_Br4923          FAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISR
Mflv_4418|M.gilvum_PYR-GCK          YAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVAR
Mvan_1936|M.vanbaalenii_PYR-1       YAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVAR
TH_3260|M.thermoresistible__bu      YEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISR
MAV_3863|M.avium_104                YTAAERHFSQARLNPELLMIETDHDMRNPADMINLERVAKAIAHLPGIAQ
MUL_3688|M.ulcerans_Agy99           EAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAM
MAB_4768c|M.abscessus_ATCC_199      FAAADRHFPPSKLFTEMLMVESDHDMRNSADFISLDRVSKSLVRLPGVAM
MSMEG_0185|M.smegmatis_MC2_155      FQAADRHFNQSKLFSEMLMIETDHDMRNSADFISLDRVAKALIRLPGVAM
                                      .*::**  ::: .::*:::::**:**.**:: :::::: : :  *:: 

Mb0458c|M.bovis_AF2122/97           VQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMA
Rv0450c|M.tuberculosis_H37Rv        VQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMA
MMAR_0771|M.marinum_M               VQAITRPDGTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMA
MLBr_02378|M.leprae_Br4923          VQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMA
Mflv_4418|M.gilvum_PYR-GCK          VQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQ
Mvan_1936|M.vanbaalenii_PYR-1       VQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQ
TH_3260|M.thermoresistible__bu      VQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQ
MAV_3863|M.avium_104                VQSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDLLKQADNLK
MUL_3688|M.ulcerans_Agy99           IQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQ
MAB_4768c|M.abscessus_ATCC_199      VQSITRPMGRALEHASLPYLFTTQGSGNGQQLPFTKAQNANTDRQAQIMA
MSMEG_0185|M.smegmatis_MC2_155      VQSITRPLGRPLEHATIPYLFTTQGSTNGQQLPFSEQANENTDRQAEIQA
                                    :* :*** * .:.*:::.:  :  .        : .    :    *:   

Mb0458c|M.bovis_AF2122/97           TTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRP
Rv0450c|M.tuberculosis_H37Rv        TTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRP
MMAR_0771|M.marinum_M               KTIALMRRMYGLMTQLANNTHKMVGDTIEMQQITKELRDHIANFDDFFRP
MLBr_02378|M.leprae_Br4923          ETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRP
Mflv_4418|M.gilvum_PYR-GCK          TNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRP
Mvan_1936|M.vanbaalenii_PYR-1       TNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRP
TH_3260|M.thermoresistible__bu      LMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRP
MAV_3863|M.avium_104                DTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIANFDDFFRP
MUL_3688|M.ulcerans_Agy99           VLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRP
MAB_4768c|M.abscessus_ATCC_199      HSVAVLRQTTDLTQQLADEMHNTVVTMEDMQQVTQDMNEKVSNLDDFMRP
MSMEG_0185|M.smegmatis_MC2_155      RSVEVLQHVITITQQMSAELHSTVLTFENLKEVTDEVNEGISNLDDFLRP
                                      :    :   :   :            .      .:.: ::::*** **

Mb0458c|M.bovis_AF2122/97           IRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRL
Rv0450c|M.tuberculosis_H37Rv        IRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRL
MMAR_0771|M.marinum_M               IRSYFYWEKHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRL
MLBr_02378|M.leprae_Br4923          IRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLL
Mflv_4418|M.gilvum_PYR-GCK          VRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDEL
Mvan_1936|M.vanbaalenii_PYR-1       VRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDAL
TH_3260|M.thermoresistible__bu      IRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDL
MAV_3863|M.avium_104                VRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTASLDKLDAG
MUL_3688|M.ulcerans_Agy99           MRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGL
MAB_4768c|M.abscessus_ATCC_199      LRNYFYWEPHCFDIPVCQSFRSLFDMLDSIDKLAADIKDAVGSLEVVDRL
MSMEG_0185|M.smegmatis_MC2_155      LKNYFYWEPHCFDIPVCFAMRSLFDSLDGIDSLDEQIGNAVVSFEAIDRL
                                    ::.***** **:.:* * ::**:** **.:: :   :      :      

Mb0458c|M.bovis_AF2122/97           MPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAF
Rv0450c|M.tuberculosis_H37Rv        MPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAF
MMAR_0771|M.marinum_M               MPQMIETFPPMIETMESMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAF
MLBr_02378|M.leprae_Br4923          MPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAF
Mflv_4418|M.gilvum_PYR-GCK          MPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAF
Mvan_1936|M.vanbaalenii_PYR-1       MPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAF
TH_3260|M.thermoresistible__bu      MPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAF
MAV_3863|M.avium_104                QQKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDTATALGQAY
MUL_3688|M.ulcerans_Agy99           TSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSF
MAB_4768c|M.abscessus_ATCC_199      LPQMVALLKLTANDQEALQALIVNTYGQTNLQATATDQTFDDMINVGNDF
MSMEG_0185|M.smegmatis_MC2_155      LPQMITQLERMIADSRALLGVITNNYGPAHLQSTQTDQTYYDQINVGNDF
                                      :::  :       .    :                        :*: :

Mb0458c|M.bovis_AF2122/97           DAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPE
Rv0450c|M.tuberculosis_H37Rv        DAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPE
MMAR_0771|M.marinum_M               DAAKNDDSFYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILHRGDPQSAQ
MLBr_02378|M.leprae_Br4923          DTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVA
Mflv_4418|M.gilvum_PYR-GCK          DDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVE
Mvan_1936|M.vanbaalenii_PYR-1       DDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVE
TH_3260|M.thermoresistible__bu      DQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPE
MAV_3863|M.avium_104                DAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISHEGDPATPE
MUL_3688|M.ulcerans_Agy99           DASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPE
MAB_4768c|M.abscessus_ATCC_199      DASRSDDFFYIPHEAFDNEDIKTGMTLMMSPDGKAARFIVTHMGNAMGPE
MSMEG_0185|M.smegmatis_MC2_155      DAARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAMAPE
                                    * : .** **:* *.* * :.: .:  ::*.**::.*::: * *:.    

Mb0458c|M.bovis_AF2122/97           GIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAA
Rv0450c|M.tuberculosis_H37Rv        GIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAA
MMAR_0771|M.marinum_M               GIASIDQIRTAAEESLKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAG
MLBr_02378|M.leprae_Br4923          GIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAG
Mflv_4418|M.gilvum_PYR-GCK          GISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAG
Mvan_1936|M.vanbaalenii_PYR-1       GISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAG
TH_3260|M.thermoresistible__bu      GLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAA
MAV_3863|M.avium_104                GISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIAG
MUL_3688|M.ulcerans_Agy99           GISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAV
MAB_4768c|M.abscessus_ATCC_199      GIEHVNDFPDAITTALKETSLAGAQVYIGGAGSNNKDIKQYAASDLLIAA
MSMEG_0185|M.smegmatis_MC2_155      GIEHVEQFPDAIKMALKETSLAGAKIYIGGAASNNLDIKTYAASDLLIVA
                                    *:  :     *   .:* :.* .: :*:.*:.:   *:      **:*. 

Mb0458c|M.bovis_AF2122/97           ISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIH
Rv0450c|M.tuberculosis_H37Rv        ISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIH
MMAR_0771|M.marinum_M               ISSLCLIFIIMLILTRAFVAAAVIVGTVALSLGASFGMSVLLWQHILNID
MLBr_02378|M.leprae_Br4923          ISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIE
Mflv_4418|M.gilvum_PYR-GCK          IAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLA
Mvan_1936|M.vanbaalenii_PYR-1       IAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLA
TH_3260|M.thermoresistible__bu      IAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLE
MAV_3863|M.avium_104                IAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIK
MUL_3688|M.ulcerans_Agy99           VSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIK
MAB_4768c|M.abscessus_ATCC_199      IAAFTLIFLIMMVITRSLVAPFVIIGTVAFSFAGAFGLSVLIWQHLVGLP
MSMEG_0185|M.smegmatis_MC2_155      IAAFVLIFLIMLYLTRSLVAALVIPGTVAFSFAGAFGLSVMMWQHLIGLP
                                    :::. **::**: :**:.:*. ** **.  *:..:**:**::** :. : 

Mb0458c|M.bovis_AF2122/97           LHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKV
Rv0450c|M.tuberculosis_H37Rv        LHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKV
MMAR_0771|M.marinum_M               LHYMVLAMSVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKV
MLBr_02378|M.leprae_Br4923          LHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKV
Mflv_4418|M.gilvum_PYR-GCK          LHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSV
Mvan_1936|M.vanbaalenii_PYR-1       LHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSV
TH_3260|M.thermoresistible__bu      MHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSV
MAV_3863|M.avium_104                LYWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGSGAV
MUL_3688|M.ulcerans_Agy99           IHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGV
MAB_4768c|M.abscessus_ATCC_199      LHWLILPLTFIILVAVGSDYNLLLIARLKEETDAGLNTGLIRALGSTGGV
MSMEG_0185|M.smegmatis_MC2_155      LHWLILPLSFIILVAVGSDYNLLLISRVKEETGAGLNTGLIRALGSTGAV
                                    ::::  .::.*:*:***:*****:::*.::*  .**:**:**::..:* *

Mb0458c|M.bovis_AF2122/97           VTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIA
Rv0450c|M.tuberculosis_H37Rv        VTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIA
MMAR_0771|M.marinum_M               VTNAGLVFAFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIA
MLBr_02378|M.leprae_Br4923          VTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIA
Mflv_4418|M.gilvum_PYR-GCK          VTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVA
Mvan_1936|M.vanbaalenii_PYR-1       VTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVA
TH_3260|M.thermoresistible__bu      VTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIA
MAV_3863|M.avium_104                VTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVRSFMTPSVA
MUL_3688|M.ulcerans_Agy99           VTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIA
MAB_4768c|M.abscessus_ATCC_199      VTSAGLVFAFTMLAMLASDLRTIGQVGTTVCIGLLLDTLIVRSFIVPALV
MSMEG_0185|M.smegmatis_MC2_155      VTSAGLVFAFTMLSMLVSDLRTIGQLGTTVCIGLLLDTMIVRSLVVPCLL
                                    ** *****..**  :  :.* .:.*.*:*: :***:**::**::: *.: 

Mb0458c|M.bovis_AF2122/97           ALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG--------
Rv0450c|M.tuberculosis_H37Rv        ALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG--------
MMAR_0771|M.marinum_M               ALLGRWFWWPMRVRTRPARTPSSPTADPEPDRALAMSGER----------
MLBr_02378|M.leprae_Br4923          ALLGRWFWWPQQGRTRPLLTVAAPVG-LPPDRSLVYSD------------
Mflv_4418|M.gilvum_PYR-GCK          ALLGRWFWWPQKFRSAASERRLARIGVQ-PATAGR---------------
Mvan_1936|M.vanbaalenii_PYR-1       ALLGRWFWWPQKVRSHASQRRLAALNH-----------------------
TH_3260|M.thermoresistible__bu      TLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV------------
MAV_3863|M.avium_104                ALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDPAVAPETPS
MUL_3688|M.ulcerans_Agy99           TLLGRWFWWPQVVHPRGDNARPRVAAPTH---------------------
MAB_4768c|M.abscessus_ATCC_199      RLLGTWFWWPTRVLARPRREPVRS--------------------------
MSMEG_0185|M.smegmatis_MC2_155      RLLGPWFWWPTFIRQRPLRQAVRQRERADVV-------------------
                                     *** *****                                        

Mb0458c|M.bovis_AF2122/97           -------
Rv0450c|M.tuberculosis_H37Rv        -------
MMAR_0771|M.marinum_M               -------
MLBr_02378|M.leprae_Br4923          -------
Mflv_4418|M.gilvum_PYR-GCK          -------
Mvan_1936|M.vanbaalenii_PYR-1       -------
TH_3260|M.thermoresistible__bu      -------
MAV_3863|M.avium_104                AARHSRG
MUL_3688|M.ulcerans_Agy99           -------
MAB_4768c|M.abscessus_ATCC_199      -------
MSMEG_0185|M.smegmatis_MC2_155      -------