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TTDQATRSVVAQTIRRLSVPILLVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAMQHIGKVFHE YDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEHVQNFWGDPLTAAGSQSKDGKAAYVQVYLA GNQGDALANESVDAIRNIVEHTPPPPGVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVYR SVTAVFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAAGTDYAIFFVGRYHEARHEGQDR ETAYYTMYRGTTHVVLGSGLTVAGAVLCLRFTRLNYFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFG LFDPKRQMATRGWRRIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPASAPANTGYTAAER HFSQARLNPELLMIETDHDMRNPADMINLERVAKAIAHLPGIAQVQSMTRPLGTPIEHTSLAFQISAGSI GSIENLQYQKERAEDLLKQADNLKDTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIANFDD FFRPVRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTASLDKLDAGQQKLVTLLPPQIADQE KNLALTLSNYATNLGINAQTRANTDTATALGQAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAA RMIISHEGDPATPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIAGIAALSL ILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIKLYWICLALSVIILLAVGSDYNLLLIS RFREEIHAGLNTGIIRSMAGSGAVVTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVRSFMT PSVAALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDPAVAPETPSAARHSRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3863 | - | - | 100% (972) | MmpL4 protein |
| M. avium 104 | MAV_4696 | - | 0.0 | 64.50% (938) | MmpL4 protein |
| M. avium 104 | MAV_2510 | - | 0.0 | 58.25% (946) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1583 | mmpL6 | 0.0 | 75.03% (957) | transmembrane transport protein MmpL6 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 59.40% (941) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 59.33% (954) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 59.25% (935) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_0987c | - | 0.0 | 67.09% (945) | membrane protein MmpL |
| M. marinum M | MMAR_0775 | - | 0.0 | 62.62% (963) | MmpL family transport protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 58.66% (924) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 55.60% (946) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 57.72% (939) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 60.34% (933) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4418|M.gilvum_PYR-GCK ---------------------------------MADAGRSGIGRIIRVLA
Mvan_1936|M.vanbaalenii_PYR-1 ---------------------------------MADAGRSGIGRIIHLLA
MSMEG_3496|M.smegmatis_MC2_155 ----------------MSNPSHDAPTDAMGVSGPKHARPGGIAKWIRVLA
MUL_0757|M.ulcerans_Agy99 ----------------MTATTTDTPTDVVPP--AEHPPRPFIPRMIRTFA
MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
Rv0450c|M.tuberculosis_H37Rv ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
MLBr_02378|M.leprae_Br4923 ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA
TH_3056|M.thermoresistible__bu ----------------------MSVLDR----VGVEPRRPRVASFIRRYS
MAV_3863|M.avium_104 -------------------------------MTTDQATRSVVAQTIRRLS
Mb1583|M.bovis_AF2122/97 -------------------------------MSNHHRPRPWLPHTIRRLS
MAB_0987c|M.abscessus_ATCC_199 -------------------------------MSANHAHESRAAKIVRRLA
:: :
Mflv_4418|M.gilvum_PYR-GCK VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF
Mvan_1936|M.vanbaalenii_PYR-1 VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF
MSMEG_3496|M.smegmatis_MC2_155 VPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVF
MUL_0757|M.ulcerans_Agy99 VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF
MMAR_0775|M.marinum_M VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF
Rv0450c|M.tuberculosis_H37Rv VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923 VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
TH_3056|M.thermoresistible__bu VLIILGWVALTVLATVAVPPLEAVEREKSLSLIPYDAPAFAAMHRMGELF
MAV_3863|M.avium_104 VPILLVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAMQHIGKVF
Mb1583|M.bovis_AF2122/97 LPILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVF
MAB_0987c|M.abscessus_ATCC_199 VPIVLFWVAIAAVTNATVPQLEVVGEERSAPLNAADAPSTLAMRHIGKVF
: ::: *: : . :* *: * . : . : :* ::* *
Mflv_4418|M.gilvum_PYR-GCK EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD
Mvan_1936|M.vanbaalenii_PYR-1 DEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGD
MSMEG_3496|M.smegmatis_MC2_155 EEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGD
MUL_0757|M.ulcerans_Agy99 REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD
MMAR_0775|M.marinum_M NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD
Rv0450c|M.tuberculosis_H37Rv KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923 NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD
TH_3056|M.thermoresistible__bu DEPDSESIAIIVLEGQEPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGD
MAV_3863|M.avium_104 HEYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEHVQNFWGD
Mb1583|M.bovis_AF2122/97 HEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGD
MAB_0987c|M.abscessus_ATCC_199 NEFDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHVQHVADYWGD
* .::* ::::**:.*** **.:*: :: .* . *: : : ***
Mflv_4418|M.gilvum_PYR-GCK PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTPAPPGI
Mvan_1936|M.vanbaalenii_PYR-1 PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTPAPPGL
MSMEG_3496|M.smegmatis_MC2_155 PLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVPAPPGV
MUL_0757|M.ulcerans_Agy99 PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQAPPGV
MMAR_0775|M.marinum_M PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTPAPPGV
Rv0450c|M.tuberculosis_H37Rv PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPAPPGI
MLBr_02378|M.leprae_Br4923 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPAPPGI
TH_3056|M.thermoresistible__bu PLTAGAAQSDDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIVERTPAPEGV
MAV_3863|M.avium_104 PLTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIVEHTPPPPGV
Mb1583|M.bovis_AF2122/97 PLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTPPPAGV
MAB_0987c|M.abscessus_ATCC_199 PITAGGSQSKDGKAAYVQVYVAGNQGEALSNESVDAVRRIIAETPAPDGI
*:** . ** ** *::** *. * *:: *:: :: .* *:
Mflv_4418|M.gilvum_PYR-GCK KAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVLI
Mvan_1936|M.vanbaalenii_PYR-1 KAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVLI
MSMEG_3496|M.smegmatis_MC2_155 KAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILT
MUL_0757|M.ulcerans_Agy99 KVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIM
MMAR_0775|M.marinum_M KAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITVISV
Rv0450c|M.tuberculosis_H37Rv KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
MLBr_02378|M.leprae_Br4923 TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL
TH_3056|M.thermoresistible__bu ETFVTGPAALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVL
MAV_3863|M.avium_104 KAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVYRS-VTAVFV
Mb1583|M.bovis_AF2122/97 KAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVVTMVLV
MAB_0987c|M.abscessus_ATCC_199 KAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVVYRSLITTALV
.:*:* :. :* . : :. ** ** .:** *
Mflv_4418|M.gilvum_PYR-GCK LFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAI
Mvan_1936|M.vanbaalenii_PYR-1 LFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFAI
MSMEG_3496|M.smegmatis_MC2_155 LVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLI
MUL_0757|M.ulcerans_Agy99 LTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLI
MMAR_0775|M.marinum_M LVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAIFVL
Rv0450c|M.tuberculosis_H37Rv LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
MLBr_02378|M.leprae_Br4923 LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT
TH_3056|M.thermoresistible__bu LLTVAVELQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFF
MAV_3863|M.avium_104 LVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAAGTDYAIFFV
Mb1583|M.bovis_AF2122/97 LITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAIFVL
MAB_0987c|M.abscessus_ATCC_199 LAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIAAGTDYAIFFV
* * .:** :* *. :**:.: ..**. : ***.***.**
Mflv_4418|M.gilvum_PYR-GCK GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF
Mvan_1936|M.vanbaalenii_PYR-1 GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF
MSMEG_3496|M.smegmatis_MC2_155 GRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYF
MUL_0757|M.ulcerans_Agy99 GRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYF
MMAR_0775|M.marinum_M GRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRLPYF
Rv0450c|M.tuberculosis_H37Rv GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYF
MLBr_02378|M.leprae_Br4923 GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF
TH_3056|M.thermoresistible__bu GRYQEAREAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHF
MAV_3863|M.avium_104 GRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLCLRFTRLNYF
Mb1583|M.bovis_AF2122/97 GRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRLPYF
MAB_0987c|M.abscessus_ATCC_199 GRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGLTVAGALFCLSFTRLPYF
***:*** :.: :: * : .. :*::.**:*::** ** *:*: :*
Mflv_4418|M.gilvum_PYR-GCK QTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRI
Mvan_1936|M.vanbaalenii_PYR-1 QTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGWRRI
MSMEG_3496|M.smegmatis_MC2_155 QSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKL
MUL_0757|M.ulcerans_Agy99 QTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKI
MMAR_0775|M.marinum_M QTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGWRRV
Rv0450c|M.tuberculosis_H37Rv QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
MLBr_02378|M.leprae_Br4923 QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRI
TH_3056|M.thermoresistible__bu QPLGIPGAVGLLVAVAVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRI
MAV_3863|M.avium_104 QSLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKRQMATRGWRRI
Mb1583|M.bovis_AF2122/97 QSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRRMRTRGWRRI
MAB_0987c|M.abscessus_ATCC_199 QTLGVPAALGVLVTLAAALTLAPAVLVIAGRFG-LMEPKRAMRTRGWRRI
*.:* * ::* :.: .:*:: .: : : . * ::*** : **::
Mflv_4418|M.gilvum_PYR-GCK GVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGYA
Mvan_1936|M.vanbaalenii_PYR-1 GVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGYA
MSMEG_3496|M.smegmatis_MC2_155 GAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYA
MUL_0757|M.ulcerans_Agy99 GAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYS
MMAR_0775|M.marinum_M GTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNVGYT
Rv0450c|M.tuberculosis_H37Rv GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
MLBr_02378|M.leprae_Br4923 GTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFA
TH_3056|M.thermoresistible__bu GTAVVRWPVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYK
MAV_3863|M.avium_104 GTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPASAPANTGYT
Mb1583|M.bovis_AF2122/97 GTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANIGYM
MAB_0987c|M.abscessus_ATCC_199 GTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMPSSVPSNVGYA
*. :**** *:* : :::**::****...*. : ::* *:. *:
Mflv_4418|M.gilvum_PYR-GCK VADQHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARV
Mvan_1936|M.vanbaalenii_PYR-1 VADRHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARV
MSMEG_3496|M.smegmatis_MC2_155 AADRHFSQARMN-PELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRV
MUL_0757|M.ulcerans_Agy99 AAERHFSQARMN-PEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRV
MMAR_0775|M.marinum_M AADRHFSQARMN-PELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVARV
Rv0450c|M.tuberculosis_H37Rv AADRHFSQARMK-PEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
MLBr_02378|M.leprae_Br4923 AADRHFPQARMK-PEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV
TH_3056|M.thermoresistible__bu AAARHFPASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANV
MAV_3863|M.avium_104 AAERHFSQARLN-PELLMIETDHDMRNPADMINLERVAKAIAHLPGIAQV
Mb1583|M.bovis_AF2122/97 AAERHFPQARLN-PELLMIETDHDMRNPADMLILDRIAKAVFHLPGIGLV
MAB_0987c|M.abscessus_ATCC_199 AAERHFSVARLN-PELLMIETDFDMRNPAGMVLLERVAKSVLHARGVALV
.* :** : :. *:::::*:* *:**.:.:: ::::*: : *:. *
Mflv_4418|M.gilvum_PYR-GCK QTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQT
Mvan_1936|M.vanbaalenii_PYR-1 QTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQT
MSMEG_3496|M.smegmatis_MC2_155 QAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQK
MUL_0757|M.ulcerans_Agy99 QAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQT
MMAR_0775|M.marinum_M QAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAMQD
Rv0450c|M.tuberculosis_H37Rv QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
MLBr_02378|M.leprae_Br4923 QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE
TH_3056|M.thermoresistible__bu QSVTRPEGRQIEHTTIPFMLSMSQASQRLALPFQRARMDDMLKQADELTE
MAV_3863|M.avium_104 QSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDLLKQADNLKD
Mb1583|M.bovis_AF2122/97 QAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAEELGK
MAB_0987c|M.abscessus_ATCC_199 QSITRPLGTPITHSSIPFQISASSASQLMNLSQQQNQALYLSQQADQMTN
*::*** * : *:::.* :* . : : . :
Mflv_4418|M.gilvum_PYR-GCK NVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPV
Mvan_1936|M.vanbaalenii_PYR-1 NVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPV
MSMEG_3496|M.smegmatis_MC2_155 SVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPI
MUL_0757|M.ulcerans_Agy99 NIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPI
MMAR_0775|M.marinum_M SIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWRPI
Rv0450c|M.tuberculosis_H37Rv TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
MLBr_02378|M.leprae_Br4923 TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI
TH_3056|M.thermoresistible__bu TIALMRRMQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPI
MAV_3863|M.avium_104 TIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIANFDDFFRPV
Mb1583|M.bovis_AF2122/97 TIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDFFRPI
MAB_0987c|M.abscessus_ATCC_199 TIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIANFDDQFRPI
.: : . : ** .:*: :*::** **:
Mflv_4418|M.gilvum_PYR-GCK RNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELM
Mvan_1936|M.vanbaalenii_PYR-1 RNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALM
MSMEG_3496|M.smegmatis_MC2_155 RNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELM
MUL_0757|M.ulcerans_Agy99 RSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLM
MMAR_0775|M.marinum_M RSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDILM
Rv0450c|M.tuberculosis_H37Rv RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
MLBr_02378|M.leprae_Br4923 RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM
TH_3056|M.thermoresistible__bu RNYFHWEPHCYNIPICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALM
MAV_3863|M.avium_104 RSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTASLDKLDAGQ
Mb1583|M.bovis_AF2122/97 RSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQ
MAB_0987c|M.abscessus_ATCC_199 RNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTGSLTKLDALQ
*.**:** ** .:* * ::**:**::**:: : : : : .:
Mflv_4418|M.gilvum_PYR-GCK PQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFD
Mvan_1936|M.vanbaalenii_PYR-1 PQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFD
MSMEG_3496|M.smegmatis_MC2_155 PQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFD
MUL_0757|M.ulcerans_Agy99 PQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFD
MMAR_0775|M.marinum_M PQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKAFD
Rv0450c|M.tuberculosis_H37Rv PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
MLBr_02378|M.leprae_Br4923 PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD
TH_3056|M.thermoresistible__bu PQMLVQFPQMIETMESSRTMILTMHATMSGIFDQMESSSENATAMGKAFD
MAV_3863|M.avium_104 QKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDTATALGQAYD
Mb1583|M.bovis_AF2122/97 PQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFD
MAB_0987c|M.abscessus_ATCC_199 PKLVDLIPPQIAIQEKNRDLTLSNYAINNGTNTQNEESTRTATELGKAFD
:: :* * . * . * :*:*:*
Mflv_4418|M.gilvum_PYR-GCK DSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEG
Mvan_1936|M.vanbaalenii_PYR-1 DSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEG
MSMEG_3496|M.smegmatis_MC2_155 ASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEG
MUL_0757|M.ulcerans_Agy99 SSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAG
MMAR_0775|M.marinum_M AARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPASTEG
Rv0450c|M.tuberculosis_H37Rv AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
MLBr_02378|M.leprae_Br4923 TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG
TH_3056|M.thermoresistible__bu ASHNDDSFYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEG
MAV_3863|M.avium_104 AAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISHEGDPATPEG
Mb1583|M.bovis_AF2122/97 AAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEG
MAB_0987c|M.abscessus_ATCC_199 DAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMIITHQGDPQTSEG
: ******:***.: * *:* :: *:*.**::.*::: :.*** : *
Mflv_4418|M.gilvum_PYR-GCK ISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGI
Mvan_1936|M.vanbaalenii_PYR-1 ISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGI
MSMEG_3496|M.smegmatis_MC2_155 IKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGI
MUL_0757|M.ulcerans_Agy99 INHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGI
MMAR_0775|M.marinum_M ISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIAGV
Rv0450c|M.tuberculosis_H37Rv IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
MLBr_02378|M.leprae_Br4923 IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI
TH_3056|M.thermoresistible__bu MALVEPIYIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAI
MAV_3863|M.avium_104 ISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIAGI
Mb1583|M.bovis_AF2122/97 ISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGI
MAB_0987c|M.abscessus_ATCC_199 IAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQKYDLLMAAL
: : * * :::* **: .: :*:.*:.: :*: :* :**::*.:
Mflv_4418|M.gilvum_PYR-GCK AAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
Mvan_1936|M.vanbaalenii_PYR-1 AAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
MSMEG_3496|M.smegmatis_MC2_155 AALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLEL
MUL_0757|M.ulcerans_Agy99 SALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIEL
MMAR_0775|M.marinum_M AAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGVEL
Rv0450c|M.tuberculosis_H37Rv SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
MLBr_02378|M.leprae_Br4923 SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL
TH_3056|M.thermoresistible__bu SAVCLIFMIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQL
MAV_3863|M.avium_104 AALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIKL
Mb1583|M.bovis_AF2122/97 AALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQL
MAB_0987c|M.abscessus_ATCC_199 ASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVVWQYIFGIPL
::: **::**:.:**:.:*: ****** :**.****:**::** ::.: *
Mflv_4418|M.gilvum_PYR-GCK HWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVV
Mvan_1936|M.vanbaalenii_PYR-1 HWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVV
MSMEG_3496|M.smegmatis_MC2_155 HWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVV
MUL_0757|M.ulcerans_Agy99 HWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVV
MMAR_0775|M.marinum_M HWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGGVV
Rv0450c|M.tuberculosis_H37Rv HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
MLBr_02378|M.leprae_Br4923 HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV
TH_3056|M.thermoresistible__bu HWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVV
MAV_3863|M.avium_104 YWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGSGAVV
Mb1583|M.bovis_AF2122/97 YWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVV
MAB_0987c|M.abscessus_ATCC_199 YWVIFPLAVIILLAVGADYNLLLISRFKEETGAGLKTGIIRAIAGTGGVV
::: :.::**:*****:****:*::*:::* .*::*****::.*:* **
Mflv_4418|M.gilvum_PYR-GCK TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
Mvan_1936|M.vanbaalenii_PYR-1 TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
MSMEG_3496|M.smegmatis_MC2_155 TSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAA
MUL_0757|M.ulcerans_Agy99 TAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAA
MMAR_0775|M.marinum_M TTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
Rv0450c|M.tuberculosis_H37Rv TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
TH_3056|M.thermoresistible__bu TMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAA
MAV_3863|M.avium_104 TSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVRSFMTPSVAA
Mb1583|M.bovis_AF2122/97 TAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAV
MAB_0987c|M.abscessus_ATCC_199 TAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRSFLTPAIAT
* ****** ** *: :.* ::.*:****.:******:::*:*: *::*.
Mflv_4418|M.gilvum_PYR-GCK LLGRWFWWPQKFRSAASERRLARIGVQPATAGR-----------------
Mvan_1936|M.vanbaalenii_PYR-1 LLGRWFWWPQKVRSHASQRRLAALNH------------------------
MSMEG_3496|M.smegmatis_MC2_155 LMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV--------------
MUL_0757|M.ulcerans_Agy99 LLGKWFWWPQVVRQRPAPQPWPTPAP-TPPPATTSV--------------
MMAR_0775|M.marinum_M LMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPEDTNT
Rv0450c|M.tuberculosis_H37Rv LLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG---------
MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD-------------
TH_3056|M.thermoresistible__bu ILGRWFWWPQRVRTRPASAMLRPVGPRPLVRSLLLRD-------------
MAV_3863|M.avium_104 LLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDPAVAPETPSA
Mb1583|M.bovis_AF2122/97 LLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND---DPRTQVA
MAB_0987c|M.abscessus_ATCC_199 MLGRWFWWPINIRTRPAP---KPFGPKPTG--------ADDTTGPIPVSG
::*:***** * .
Mflv_4418|M.gilvum_PYR-GCK ----------
Mvan_1936|M.vanbaalenii_PYR-1 ----------
MSMEG_3496|M.smegmatis_MC2_155 ----------
MUL_0757|M.ulcerans_Agy99 ----------
MMAR_0775|M.marinum_M ERLAVSSPHY
Rv0450c|M.tuberculosis_H37Rv ----------
MLBr_02378|M.leprae_Br4923 ----------
TH_3056|M.thermoresistible__bu ----------
MAV_3863|M.avium_104 ARHSRG----
Mb1583|M.bovis_AF2122/97 THR-------
MAB_0987c|M.abscessus_ATCC_199 ----------