For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_2037 (-)

annotation: putative membrane protein MmpL
coordinates: 2036419 - 2039298
length: 959

VGNKHVGRDRGERRPFVAHAVRVLAIPIVLFWVGVAVLLSVLVPKLDGVTKQHAGPMVPLDAPSQRAMLH
IGEKFQESTSTSLAYILLETEGRILGDADHKYYDELIRLLDADKQHVQFIMNMWGKPITAAGSQSPDNKA
AYVMLRLVGDIGEAAANESTIALRKTVQDTLQRTPPPPGLRVYVSGAAPLSADLLDAGDKSMKRVLLFTI
AVIIIMLVLVYRSIACVVLILLTVAFEFTVSNGIVSFFVVHNIIGISTFATSMVESLIIAAGTDYGIFLL
GRYHEARNAGEDRDRAFYTTFHGVSHVILGSGLTIAGACLCLGFARLGYFNTMGPACAIAMLVTVAAALT
LGPALLAIASKFGLLDPKQTGQSRGWRRVGTIVVRWPKPVLVASSAAVLVGAVFLPSYRVSYNERAFQPV
NTPANAGFMASDRHFAGGKLNSEMLLIESDHDMRNPADFISLDHVAKTIFHTPGIAQVQGITRPEGRPME
RASIANILAGQGSSSGQQLPFTENQVADLDNQVAVMDHTISIMQTVIGLMDQMTQLTHEMVGTMEEMKAL
ADQVEVNISAVDDFLRPIKNYYYWEPHCADIPICWMGRSMFESMDSIDGMTALTAEALASMQVMDQLLPR
MLAQTRMALSDMTIMRGMMVKSRGTQALNTYTAADDANDMIDIGQDFDDSRNDDLFYAPKYIFSNTDFQV
ALRFLVSPDGTAARFIINHDGEALSPEGVAHVNAIEKAAYEGLKGTSLAGAKIYLGGSASNYRDIEQYVK
SDLLIAAIASFTLIFVIMLIITRSLIAACTIIGTVAFSFSGAFGLGILIWQHIIGLNLHWMVLPLTFILL
VAVGSDYNLLLIARMKEELQGGIQTGIIRSVGSTGGVVTAAGLVFAFTMLSMVPNDLRAISQVGSIICVG
LLLDTLIVRSFIVPAIARILGPWFWWPRVVRWRPAHASGAVLTSAPKGT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2037--100% (959)putative membrane protein MmpL
M. abscessus ATCC 19977MAB_4768c-0.056.55% (932) putative membrane protein, MmpL
M. abscessus ATCC 19977MAB_3562c-0.055.47% (932) MmpL family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.050.69% (945) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_4418-0.050.43% (930) transport protein
M. tuberculosis H37RvRv0450cmmpL40.050.79% (945) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.048.94% (940) hypothetical protein MLBr_02378
M. marinum MMMAR_0775-0.049.31% (945) MmpL family transport protein
M. avium 104MAV_4755-0.049.84% (915) MmpL4 protein
M. smegmatis MC2 155MSMEG_0185-0.054.78% (931) MmpL6 protein
M. thermoresistible (build 8)TH_3260-0.046.82% (929) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.048.12% (933) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.050.37% (937) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4418|M.gilvum_PYR-GCK          ---------------------------------MADAGRSGIGRIIRVLA
Mvan_1936|M.vanbaalenii_PYR-1       ---------------------------------MADAGRSGIGRIIHLLA
TH_3260|M.thermoresistible__bu      ------------MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLS
MUL_0757|M.ulcerans_Agy99           ------------MTAT-----TTDTPTDVVPPAEHPPRP-FIPRMIRTFA
MMAR_0775|M.marinum_M               MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
Mb0458c|M.bovis_AF2122/97           ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
Rv0450c|M.tuberculosis_H37Rv        ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
MLBr_02378|M.leprae_Br4923          ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA
MAV_4755|M.avium_104                -----------------------------------------------MLS
MAB_2037|M.abscessus_ATCC_1997      -------------------------MGNKHVGRDRGERRPFVAHAVRVLA
MSMEG_0185|M.smegmatis_MC2_155      -------------------------MPGQVRMSAHRAGRPFFARTVRVLA
                                                                                    ::

Mflv_4418|M.gilvum_PYR-GCK          VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF
Mvan_1936|M.vanbaalenii_PYR-1       VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF
TH_3260|M.thermoresistible__bu      LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF
MUL_0757|M.ulcerans_Agy99           VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF
MMAR_0775|M.marinum_M               VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF
Mb0458c|M.bovis_AF2122/97           VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
Rv0450c|M.tuberculosis_H37Rv        VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923          VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
MAV_4755|M.avium_104                LPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKF
MAB_2037|M.abscessus_ATCC_1997      IPIVLFWVGVAVLLSVLVPKLDGVTKQHAGPMVPLDAPSQRAMLHIGEKF
MSMEG_0185|M.smegmatis_MC2_155      VPIIVFWGLLAVTTNTFIPQVEHVADELAGPMIPNYAPSQVALLHIGEKF
                                    :*: : *  : .      *.:: * .  :  : .  * :  :: ::*  *

Mflv_4418|M.gilvum_PYR-GCK          EEFDSDSSAMVVLEGE-QPLGDAAHRYYDQLIDELEADTANVQHIADFWG
Mvan_1936|M.vanbaalenii_PYR-1       DEFDSDSSAMVVLEGE-QPLGDAAHRYYDELIGKLEADTANVQHVADFWG
TH_3260|M.thermoresistible__bu      DEGSSDSQVMIVLEGE-EPLGADARAFYDELVKRLEADDAHVENVQDLWS
MUL_0757|M.ulcerans_Agy99           REGDSDSAAMIVLEGQ-EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWG
MMAR_0775|M.marinum_M               NEFDTDSAVMIVLEGD-HPLGDEAHHYYDELVRKLKADKDHVQHVQDFWG
Mb0458c|M.bovis_AF2122/97           KEGDSDSFAMVIIEGN-QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWG
Rv0450c|M.tuberculosis_H37Rv        KEGDSDSFAMVIIEGN-QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWG
MLBr_02378|M.leprae_Br4923          NEGNSDSVIMIVLEGD-KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWG
MAV_4755|M.avium_104                NEFHTDSTAMVVLEGK-DKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWS
MAB_2037|M.abscessus_ATCC_1997      QESTSTSLAYILLETEGRILGDADHKYYDELIRLLDADKQHVQFIMNMWG
MSMEG_0185|M.smegmatis_MC2_155      QESDSTNLTMLVFEAD-RPLDDGDHRYYDDLVRRLQADTEHVQYVMDLWG
                                     *  : .   :::* .   *.   : :** ::  *  *  :*: : ::*.

Mflv_4418|M.gilvum_PYR-GCK          DPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP----
Mvan_1936|M.vanbaalenii_PYR-1       DPLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP----
TH_3260|M.thermoresistible__bu      DPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSE-EM
MUL_0757|M.ulcerans_Agy99           DPLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL----Q
MMAR_0775|M.marinum_M               DPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP----
Mb0458c|M.bovis_AF2122/97           DPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP----
Rv0450c|M.tuberculosis_H37Rv        DPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP----
MLBr_02378|M.leprae_Br4923          DPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP----
MAV_4755|M.avium_104                DPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTP----
MAB_2037|M.abscessus_ATCC_1997      KPITAAGSQSPDNKAAYVMLRLVGDIGEAAANESTIALRKTVQDTLQRTP
MSMEG_0185|M.smegmatis_MC2_155      KPITAAGAQSVDGKASFVLLRLAGNIGQLEANESVDAVRDIIAD----DA
                                    .*:**.* ** *.*:::*   * *  *   : *:  :::  :        

Mflv_4418|M.gilvum_PYR-GCK          APPGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVA
Mvan_1936|M.vanbaalenii_PYR-1       APPGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVA
TH_3260|M.thermoresistible__bu      APEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVI
MUL_0757|M.ulcerans_Agy99           APPGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSII
MMAR_0775|M.marinum_M               APPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLI
Mb0458c|M.bovis_AF2122/97           APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSII
Rv0450c|M.tuberculosis_H37Rv        APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSII
MLBr_02378|M.leprae_Br4923          APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFI
MAV_4755|M.avium_104                APPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIV
MAB_2037|M.abscessus_ATCC_1997      PPPGLRVYVSGAAPLSADLLDAGDKSMKRVLLFTIAVIIIMLVLVYRSIA
MSMEG_0185|M.smegmatis_MC2_155      PPQGLKVYVSGAAPLASDTLSTANSSLNNITIFTIILIVVMLLLVYRSAA
                                    .* *: .:*:* : : :*    .. *:  :   :. :*   *: *:**  

Mflv_4418|M.gilvum_PYR-GCK          TMVLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDY
Mvan_1936|M.vanbaalenii_PYR-1       TMVLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDY
TH_3260|M.thermoresistible__bu      TVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDY
MUL_0757|M.ulcerans_Agy99           TAAIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDY
MMAR_0775|M.marinum_M               TVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDY
Mb0458c|M.bovis_AF2122/97           TVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDY
Rv0450c|M.tuberculosis_H37Rv        TVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDY
MLBr_02378|M.leprae_Br4923          TVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDY
MAV_4755|M.avium_104                TTVLSLVIIGIELFAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDY
MAB_2037|M.abscessus_ATCC_1997      CVVLILLTVAFEFTVSNGIVSFFVVHNIIGISTFATSMVESLIIAAGTDY
MSMEG_0185|M.smegmatis_MC2_155      CLLVPLPAVLIEMLVAKGVIATLGHFGLIPLSSFAVNVVVALTLGAGTDY
                                         *  :     .:.*  :       * ::.:*..::  : :. ..**

Mflv_4418|M.gilvum_PYR-GCK          AIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFT
Mvan_1936|M.vanbaalenii_PYR-1       AIFAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFT
TH_3260|M.thermoresistible__bu      AIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFT
MUL_0757|M.ulcerans_Agy99           AIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFT
MMAR_0775|M.marinum_M               AIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFT
Mb0458c|M.bovis_AF2122/97           GIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFA
Rv0450c|M.tuberculosis_H37Rv        GIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFA
MLBr_02378|M.leprae_Br4923          GIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFA
MAV_4755|M.avium_104                VIFLLGRYHEARSFGQGREEAFYTAYHGVSHVILGSGLTIAGACLCLTAA
MAB_2037|M.abscessus_ATCC_1997      GIFLLGRYHEARNAGEDRDRAFYTTFHGVSHVILGSGLTIAGACLCLGFA
MSMEG_0185|M.smegmatis_MC2_155      GIFLLGRYHEARQSGESREDAYFTAYRSVAPIIIGSGLTIAGACFCLSLA
                                     **  ***:***  . .:  *:.* : ..  :::.*****:**  **  :

Mflv_4418|M.gilvum_PYR-GCK          RLPYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSR
Mvan_1936|M.vanbaalenii_PYR-1       RLPYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSR
TH_3260|M.thermoresistible__bu      RLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVR
MUL_0757|M.ulcerans_Agy99           RLPYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVR
MMAR_0775|M.marinum_M               RLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTR
Mb0458c|M.bovis_AF2122/97           RMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVR
Rv0450c|M.tuberculosis_H37Rv        RMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVR
MLBr_02378|M.leprae_Br4923          RMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVR
MAV_4755|M.avium_104                RLPYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFG-LFDPKRAIDVR
MAB_2037|M.abscessus_ATCC_1997      RLGYFNTMGPACAIAMLVTVAAALTLGPALLAIASKFG-LLDPKQTGQSR
MSMEG_0185|M.smegmatis_MC2_155      RLDYFHTMGPAVAISMLFTIAAALTLAPALLTLGSLLA-LFDPKRPTRGH
                                    *: **:::* . *:. .. : .:**:.**:: : : :  *::**:    :

Mflv_4418|M.gilvum_PYR-GCK          GWRRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPA
Mvan_1936|M.vanbaalenii_PYR-1       GWRRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPA
TH_3260|M.thermoresistible__bu      FWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPS
MUL_0757|M.ulcerans_Agy99           GWRKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPA
MMAR_0775|M.marinum_M               GWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPT
Mb0458c|M.bovis_AF2122/97           GWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPA
Rv0450c|M.tuberculosis_H37Rv        GWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPA
MLBr_02378|M.leprae_Br4923          GWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPA
MAV_4755|M.avium_104                GWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPA
MAB_2037|M.abscessus_ATCC_1997      GWRRVGTIVVRWPKPVLVASSAAVLVGAVFLPSYRVSYNERAFQPVNTPA
MSMEG_0185|M.smegmatis_MC2_155      LYRRIGTSVVRWPKPIFVASAAVVMVGAVFVPSYRVNYDDRAYQPVDAAA
                                     :*::*. :**** *::  : * .::* : :  *  .*. : : *   .:

Mflv_4418|M.gilvum_PYR-GCK          NVGYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPG
Mvan_1936|M.vanbaalenii_PYR-1       NVGYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPG
TH_3260|M.thermoresistible__bu      NAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEG
MUL_0757|M.ulcerans_Agy99           NEGYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEG
MMAR_0775|M.marinum_M               NVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPG
Mb0458c|M.bovis_AF2122/97           NQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPG
Rv0450c|M.tuberculosis_H37Rv        NQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPG
MLBr_02378|M.leprae_Br4923          NQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPG
MAV_4755|M.avium_104                NAAMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRG
MAB_2037|M.abscessus_ATCC_1997      NAGFMASDRHFAGGKLNSEMLLIESDHDMRNPADFISLDHVAKTIFHTPG
MSMEG_0185|M.smegmatis_MC2_155      NLGFQAADRHFNQSKLFSEMLMIETDHDMRNSADFISLDRVAKALIRLPG
                                    * .  .:::**  .:: .*:*::*:***:*:.:*:: ::::*: ::   *

Mflv_4418|M.gilvum_PYR-GCK          VARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQAD
Mvan_1936|M.vanbaalenii_PYR-1       VARVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQAD
TH_3260|M.thermoresistible__bu      ISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQAD
MUL_0757|M.ulcerans_Agy99           ISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVN
MMAR_0775|M.marinum_M               VARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAA
Mb0458c|M.bovis_AF2122/97           ISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQAD
Rv0450c|M.tuberculosis_H37Rv        ISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQAD
MLBr_02378|M.leprae_Br4923          ISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAE
MAV_4755|M.avium_104                IERVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQAD
MAB_2037|M.abscessus_ATCC_1997      IAQVQGITRPEGRPMERASIANILAGQGSSSGQQLPFTENQVADLDNQVA
MSMEG_0185|M.smegmatis_MC2_155      VAMVQSITRPLGRPLEHATIPYLFTTQGSTNGQQLPFSEQANENTDRQAE
                                    :  ** :*** * .:.:::*.  :: :.:       : .:   .   *. 

Mflv_4418|M.gilvum_PYR-GCK          AMQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDF
Mvan_1936|M.vanbaalenii_PYR-1       AMQTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDF
TH_3260|M.thermoresistible__bu      EMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDF
MUL_0757|M.ulcerans_Agy99           DIQTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDF
MMAR_0775|M.marinum_M               AMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDF
Mb0458c|M.bovis_AF2122/97           EMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDF
Rv0450c|M.tuberculosis_H37Rv        EMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDF
MLBr_02378|M.leprae_Br4923          NMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDF
MAV_4755|M.avium_104                ELDKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDF
MAB_2037|M.abscessus_ATCC_1997      VMDHTISIMQTVIGLMDQMTQLTHEMVGTMEEMKALADQVEVNISAVDDF
MSMEG_0185|M.smegmatis_MC2_155      IQARSVEVLQHVITITQQMSAELHSTVLTFENLKEVTDEVNEGISNLDDF
                                         :  :  :  :   :    .              ::.  :: .***

Mflv_4418|M.gilvum_PYR-GCK          FRPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERL
Mvan_1936|M.vanbaalenii_PYR-1       VRPVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERL
TH_3260|M.thermoresistible__bu      FRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRL
MUL_0757|M.ulcerans_Agy99           FRPIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERL
MMAR_0775|M.marinum_M               WRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRL
Mb0458c|M.bovis_AF2122/97           WRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREM
Rv0450c|M.tuberculosis_H37Rv        WRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREM
MLBr_02378|M.leprae_Br4923          WRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNM
MAV_4755|M.avium_104                FRPIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHM
MAB_2037|M.abscessus_ATCC_1997      LRPIKNYYYWEPHCADIPICWMGRSMFESMDSIDGMTALTAEALASMQVM
MSMEG_0185|M.smegmatis_MC2_155      LRPLKNYFYWEPHCFDIPVCFAMRSLFDSLDGIDSLDEQIGNAVVSFEAI
                                     **::.*:*** ** .:*:*   **:*:::*.:: :          :  :

Mflv_4418|M.gilvum_PYR-GCK          DELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMG
Mvan_1936|M.vanbaalenii_PYR-1       DALMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMG
TH_3260|M.thermoresistible__bu      NDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMG
MUL_0757|M.ulcerans_Agy99           DTLMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMG
MMAR_0775|M.marinum_M               DILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMG
Mb0458c|M.bovis_AF2122/97           DRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMG
Rv0450c|M.tuberculosis_H37Rv        DRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMG
MLBr_02378|M.leprae_Br4923          DLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMG
MAV_4755|M.avium_104                DRLMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEGSTLMG
MAB_2037|M.abscessus_ATCC_1997      DQLLPRMLAQTRMALSDMTIMRGMMVKSRGTQALNTYTAADDANDMIDIG
MSMEG_0185|M.smegmatis_MC2_155      DRLLPQMITQLERMIADSRALLGVITNNYGPAHLQSTQTDQTYYDQINVG
                                    : *:*::       :     :   :     .             .   :*

Mflv_4418|M.gilvum_PYR-GCK          EAFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPA
Mvan_1936|M.vanbaalenii_PYR-1       EAFDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPA
TH_3260|M.thermoresistible__bu      EAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPM
MUL_0757|M.ulcerans_Agy99           EAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPM
MMAR_0775|M.marinum_M               KAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPA
Mb0458c|M.bovis_AF2122/97           KAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQ
Rv0450c|M.tuberculosis_H37Rv        KAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQ
MLBr_02378|M.leprae_Br4923          KAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPA
MAV_4755|M.avium_104                QYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPA
MAB_2037|M.abscessus_ATCC_1997      QDFDDSRNDDLFYAPKYIFSNTDFQVALRFLVSPDGTAARFIINHDGEAL
MSMEG_0185|M.smegmatis_MC2_155      NDFDAARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAM
                                    : ** : .** ** *   *.* *.: .:. ::*.** :.**** * *:. 

Mflv_4418|M.gilvum_PYR-GCK          TVEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLL
Mvan_1936|M.vanbaalenii_PYR-1       TVEGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLL
TH_3260|M.thermoresistible__bu      TPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLI
MUL_0757|M.ulcerans_Agy99           SQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLM
MMAR_0775|M.marinum_M               STEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLL
Mb0458c|M.bovis_AF2122/97           SPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLL
Rv0450c|M.tuberculosis_H37Rv        SPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLL
MLBr_02378|M.leprae_Br4923          SVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLV
MAV_4755|M.avium_104                SVEGIKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLL
MAB_2037|M.abscessus_ATCC_1997      SPEGVAHVNAIEKAAYEGLKGTSLAGAKIYLGGSASNYRDIEQYVKSDLL
MSMEG_0185|M.smegmatis_MC2_155      APEGIEHVEQFPDAIKMALKETSLAGAKIYIGGAASNNLDIKTYAASDLL
                                    :  *:  :  .      .:* *.* .: :*:.*:.:   *:      **:

Mflv_4418|M.gilvum_PYR-GCK          IAGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHII
Mvan_1936|M.vanbaalenii_PYR-1       IAGIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHII
TH_3260|M.thermoresistible__bu      IAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIV
MUL_0757|M.ulcerans_Agy99           IAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVL
MMAR_0775|M.marinum_M               IAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIF
Mb0458c|M.bovis_AF2122/97           IAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHIL
Rv0450c|M.tuberculosis_H37Rv        IAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHIL
MLBr_02378|M.leprae_Br4923          IAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHIL
MAV_4755|M.avium_104                VAGISCLILIFTIMLIITRSVVAALVIVGTVAASLGTACGLSVLMWQDLI
MAB_2037|M.abscessus_ATCC_1997      IAAIASFTLIFVIMLIITRSLIAACTIIGTVAFSFSGAFGLGILIWQHII
MSMEG_0185|M.smegmatis_MC2_155      IVAIAAFVLIFLIMLYLTRSLVAALVIPGTVAFSFAGAFGLSVMMWQHLI
                                    :..::.. **: *** :**:.:** .* ***  *:. : *:.:::** :.

Mflv_4418|M.gilvum_PYR-GCK          GLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGT
Mvan_1936|M.vanbaalenii_PYR-1       GLALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGT
TH_3260|M.thermoresistible__bu      GLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGS
MUL_0757|M.ulcerans_Agy99           GIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGS
MMAR_0775|M.marinum_M               GVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGT
Mb0458c|M.bovis_AF2122/97           AIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGT
Rv0450c|M.tuberculosis_H37Rv        AIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGT
MLBr_02378|M.leprae_Br4923          GIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGT
MAV_4755|M.avium_104                GLGVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGAS
MAB_2037|M.abscessus_ATCC_1997      GLNLHWMVLPLTFILLVAVGSDYNLLLIARMKEELQGGIQTGIIRSVGST
MSMEG_0185|M.smegmatis_MC2_155      GLPLHWLILPLSFIILVAVGSDYNLLLISRVKEETGAGLNTGLIRALGST
                                    .: ::::::.::.::*:***:*****:::*.::*  .*::**:**.:..:

Mflv_4418|M.gilvum_PYR-GCK          GSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTP
Mvan_1936|M.vanbaalenii_PYR-1       GSVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTP
TH_3260|M.thermoresistible__bu      GSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMP
MUL_0757|M.ulcerans_Agy99           GSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTP
MMAR_0775|M.marinum_M               GGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
Mb0458c|M.bovis_AF2122/97           GKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
Rv0450c|M.tuberculosis_H37Rv        GKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
MLBr_02378|M.leprae_Br4923          GKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMP
MAV_4755|M.avium_104                GRVVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTP
MAB_2037|M.abscessus_ATCC_1997      GGVVTAAGLVFAFTMLSMVPNDLRAISQVGSIICVGLLLDTLIVRSFIVP
MSMEG_0185|M.smegmatis_MC2_155      GAVVTSAGLVFAFTMLSMLVSDLRTIGQLGTTVCIGLLLDTMIVRSLVVP
                                    * *** *****. **  :  .:* .:.::*: : :***.**::***:: *

Mflv_4418|M.gilvum_PYR-GCK          AVAALLGRWFWWPQKFRSAASERRLARIGVQPATAGR-------------
Mvan_1936|M.vanbaalenii_PYR-1       AVAALLGRWFWWPQKVRSHASQRRLAALNH--------------------
TH_3260|M.thermoresistible__bu      SIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---------
MUL_0757|M.ulcerans_Agy99           SIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-----------
MMAR_0775|M.marinum_M               SIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPE
Mb0458c|M.bovis_AF2122/97           SIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----
Rv0450c|M.tuberculosis_H37Rv        SIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----
MLBr_02378|M.leprae_Br4923          SIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD---------
MAV_4755|M.avium_104                SIAAALGHWFWWPINTIRMTRRTHHDEEAHTAPIRQPALR----------
MAB_2037|M.abscessus_ATCC_1997      AIARILGPWFWWPRVVRWRPAHASGAVLTSAPKGT---------------
MSMEG_0185|M.smegmatis_MC2_155      CLLRLLGPWFWWPTFIRQRPLRQAVRQRERADVV----------------
                                    .:   :* *****      .                              

Mflv_4418|M.gilvum_PYR-GCK          --------------
Mvan_1936|M.vanbaalenii_PYR-1       --------------
TH_3260|M.thermoresistible__bu      --------------
MUL_0757|M.ulcerans_Agy99           --------------
MMAR_0775|M.marinum_M               DTNTERLAVSSPHY
Mb0458c|M.bovis_AF2122/97           --------------
Rv0450c|M.tuberculosis_H37Rv        --------------
MLBr_02378|M.leprae_Br4923          --------------
MAV_4755|M.avium_104                --------------
MAB_2037|M.abscessus_ATCC_1997      --------------
MSMEG_0185|M.smegmatis_MC2_155      --------------