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MAASPGLWGGRTAAQRRAERRERLVGAAQEIWIEQGWAAVTMRGVCARTSLNDRYFYEDFADREDLLAAV WDGVRDELIAQISAIVAEDPDRPPLDTLRKTITLVVERVSGDPGWADIIFVRHVGSAVLEQRRIDLLHQA TAVLIAAAEPYLVKNIDRTGFRMDTLVGIGGFSELVNAWRSGLLDVSADELIEHSTRIGATLASRYLAAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4479 | - | - | 100% (210) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2070c | - | 4e-63 | 51.98% (202) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1638 | - | 2e-24 | 34.38% (192) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 2e-14 | 25.25% (198) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4631 | - | 4e-68 | 58.50% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 8e-14 | 24.75% (198) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 2e-06 | 25.23% (111) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3142 | - | 2e-66 | 55.17% (203) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 3e-20 | 32.66% (199) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1355 | - | 3e-20 | 32.83% (198) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4000 | - | 1e-20 | 32.18% (202) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1200 | - | 3e-15 | 26.27% (217) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1244 | - | 4e-20 | 33.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4631|M.gilvum_PYR-GCK MGADATKVLRPTVVCQDGHVRTRSKRWGGRTGAERRAERRQRLIDAATEI
MMAR_3142|M.marinum_M --------------MFD--VRSRNTRWGGRTGAERRAERRQQLIEAATEI
MAB_4479|M.abscessus_ATCC_1997 -------------------MAASPGLWGGRTAAQRRAERRERLVGAAQEI
MSMEG_1355|M.smegmatis_MC2_155 --------------------MTTPTRWAGVPLTDRRAERRALLVDAAFRL
TH_4000|M.thermoresistible__bu --------------------MTSPTRWAGVPLTDRRAERRALLIAAAYRL
Mvan_1244|M.vanbaalenii_PYR-1 ------------MSSAASRPAATPTRWAGVPLTDRRAERRALLVDAAFRL
MAV_3986|M.avium_104 --------------------MSSPSRWAGVPLKDRRAERRALLVEAAYRL
Mb0281c|M.bovis_AF2122/97 -------------------MTRSDRPYRGVEAAERLATRRRQLLSAGLDL
Rv0275c|M.tuberculosis_H37Rv -------------------MTRSDRPYRGVEAAERLATRRRQSLSAGLDL
MUL_1200|M.ulcerans_Agy99 -----------------------MRPYRGVEATERLATRRSQLLESGLEL
MLBr_02677|M.leprae_Br4923 ------------------------MESQRRTQEERSTATRDALTLARHRL
:* : * : :
Mflv_4631|M.gilvum_PYR-GCK WSESGW--AAVTMRGVCAKTGLNDRYFYEDFKTRDELLVAAWDGVRNEML
MMAR_3142|M.marinum_M WSESGW--AAVTMRGVCARTGLNDRYFYEDFKTREDLLVAAWDGVRNDML
MAB_4479|M.abscessus_ATCC_1997 WIEQGW--AAVTMRGVCARTSLNDRYFYEDFADREDLLAAVWDGVRDELI
MSMEG_1355|M.smegmatis_MC2_155 FGDGGE--TALSVRSVCRECGLNTRYFYESFADTDDLIGAVYDEVSALLA
TH_4000|M.thermoresistible__bu FGEGGE--AALSVRSVCRESELNSRYFYESFADVDELLGAVYDEVSAQLA
Mvan_1244|M.vanbaalenii_PYR-1 FGDGGE--QALSVRSVSREAGLNTRYFYESFTDTDDLLGAVYDRVSAELA
MAV_3986|M.avium_104 FGSEGE--AAVSVRSVCRECGLNTRYFYESFRDTDDLLGAVYDRVSEQLE
Mb0281c|M.bovis_AF2122/97 LGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELV
Rv0275c|M.tuberculosis_H37Rv LGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELV
MUL_1200|M.ulcerans_Agy99 LGSSDRDIAELTVRGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLA
MLBr_02677|M.leprae_Br4923 WRLRGY--AEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDAM
: :. . . .*..* :. . : *
Mflv_4631|M.gilvum_PYR-GCK GEVSATLAE-------RIGQPPMETIRVTIAAVVDRIAEDPGRAKILLAQ
MMAR_3142|M.marinum_M GEVSALFDE-------RVDRPPIETITAAIAIVVDRIARDPGRAHILLAQ
MAB_4479|M.abscessus_ATCC_1997 AQISAIVAE-------DPDRPPLDTLRKTITLVVERVSGDPGWADIIFVR
MSMEG_1355|M.smegmatis_MC2_155 ADVEAAM--------EGAGNSLRARTRAGIAAVLGFSSADPRRGRVLFTD
TH_4000|M.thermoresistible__bu AEVETAMAAAVEGAGEGAGDSLRARTRAGIVAVLGFSSADPRRGRILFTD
Mvan_1244|M.vanbaalenii_PYR-1 EVVEAAMS--------GAGASLPARTRAGMTAVLHFSSADPRRGRVLFTD
MAV_3986|M.avium_104 EVIAAAIE--------QAGDSLRARTRAGIAAVLGFSSADPRRGRVLFTD
Mb0281c|M.bovis_AF2122/97 ATTQAAVT----------AVPAREQTRAGMANIVRTITADARVGRLLFST
Rv0275c|M.tuberculosis_H37Rv ATTQAAVT----------AVPAREQTRAGMANIVRTITADARVGRLLFST
MUL_1200|M.ulcerans_Agy99 TTIQAAVA----------TVPPPEQARAGIAEIVRTIVGDARIGRLLFST
MLBr_02677|M.leprae_Br4923 AQIASVVAS-------SGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYA
: . . : : :::
Mflv_4631|M.gilvum_PYR-GCK HVGS-----SPLQDRRAVALQEATHLVIAASEPHLRPEADETAL--RMDT
MMAR_3142|M.marinum_M HVGS-----SPLQDRRAVALQEATQLVVEASRPHLREDADETAL--RMDT
MAB_4479|M.abscessus_ATCC_1997 HVGS-----AVLEQRRIDLLHQATAVLIAAAEPYLVKNIDRTGF--RMDT
MSMEG_1355|M.smegmatis_MC2_155 ARAN-----PVLAQRRAVTQDLLREAVLSEGG-RLNPGSDPVAA--QVGA
TH_4000|M.thermoresistible__bu ARAN-----PVLAARRAATQDQLREAVLTEGW-RLHPKSDPVAA--QVGA
Mvan_1244|M.vanbaalenii_PYR-1 ARAN-----PVLTQRRAATQDLLREAVLTEGW-RLHPDSDPTAA--MVGA
MAV_3986|M.avium_104 ARTN-----PVLAARRRATQDMLRQGVLSEGW-RLNPRSDPVAA--EVAA
Mb0281c|M.bovis_AF2122/97 QLAN-----AVITRKRAESSALFAMLSGQHAV-DTLHAPANDHV--KAVA
Rv0275c|M.tuberculosis_H37Rv QLAN-----AVITRKRAESSALFAMLSGQHAV-DTLHAPANDHV--KAVA
MUL_1200|M.ulcerans_Agy99 HLAN-----PVVVRKRTESSALFAMLSGQHAG-DALRIPANDRI--KVGA
MLBr_02677|M.leprae_Br4923 PSVLGWAAFRDVAQHYSLGMTEQQLLSEASRARQLAQPLDHVLIGKLYES
: : :
Mflv_4631|M.gilvum_PYR-GCK LVAVGGFVELITAWHAGLLDVIQGEIVEHTSRLAETLAERYLVDDAGL--
MMAR_3142|M.marinum_M LVAVGGFVEVITAWHSGLLAVTEKEVVAHTSRLAETLAQRYVVSG-----
MAB_4479|M.abscessus_ATCC_1997 LVGIGGFSELVNAWRSGLLDVSADELIEHSTRIGATLASRYLAAG-----
MSMEG_1355|M.smegmatis_MC2_155 AMYTGAMAELAQQWLAGNLGDDLDAVVDHALRLVLGR-------------
TH_4000|M.thermoresistible__bu AMYTGAMAELAQQWLAGNLGDDLDRVVDYALRLVLGR-------------
Mvan_1244|M.vanbaalenii_PYR-1 AMYTGAMAELAQQWLAGHLGDDLDAVVGYALRLVLR--------------
MAV_3986|M.avium_104 AMYTGAMAELAQQWLAGHLGGDLDAVVDYASKLVLR--------------
Mb0281c|M.bovis_AF2122/97 HFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAAT
Rv0275c|M.tuberculosis_H37Rv HFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAAT
MUL_1200|M.ulcerans_Agy99 HFIVGGVAQTISAWIEGDVELEPGQLVDQLASLLDELSDPRLYGLR----
MLBr_02677|M.leprae_Br4923 AMAIRRHHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTR
. .
Mflv_4631|M.gilvum_PYR-GCK ----------------------------
MMAR_3142|M.marinum_M ----------------------------
MAB_4479|M.abscessus_ATCC_1997 ----------------------------
MSMEG_1355|M.smegmatis_MC2_155 ----------------------------
TH_4000|M.thermoresistible__bu ----------------------------
Mvan_1244|M.vanbaalenii_PYR-1 ----------------------------
MAV_3986|M.avium_104 ----------------------------
Mb0281c|M.bovis_AF2122/97 AAKSGANDPQPPEVAGQPPSSARPARRS
Rv0275c|M.tuberculosis_H37Rv AAKSGANDPQPPEVAGQPPSSARPARRS
MUL_1200|M.ulcerans_Agy99 GTRAGATAASPAQ---------------
MLBr_02677|M.leprae_Br4923 SHRGKRGELLPRAATSSLL---------