For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGR VFDWVVAELVATTQAAVTAVPAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAM LSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVA ATAAKSGANDPQPPEVAGQPPSSARPARRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0275c | - | - | 100% (241) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) |
| M. tuberculosis H37Rv | Rv0825c | - | 1e-15 | 32.63% (190) | hypothetical protein Rv0825c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 1e-133 | 99.59% (241) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0331 | - | 5e-66 | 62.87% (202) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2494c | - | 2e-46 | 44.79% (192) | putative transcriptional regulator |
| M. marinum M | MMAR_0536 | - | 2e-79 | 70.42% (213) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4882 | - | 4e-88 | 78.64% (206) | FadD27 protein |
| M. smegmatis MC2 155 | MSMEG_0612 | - | 2e-66 | 62.44% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 8e-77 | 66.34% (205) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_1200 | - | 3e-80 | 70.89% (213) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0409 | - | 8e-59 | 65.85% (164) | FadD27 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0331|M.gilvum_PYR-GCK MGCMA----QVRPYRGVDAPARVAERRRRLLEAGLDLLGG-QLNPPELTV
Mvan_0409|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_0801|M.thermoresistible__bu MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAELTV
Rv0275c|M.tuberculosis_H37Rv ----MTRSD--RPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTI
Mb0281c|M.bovis_AF2122/97 ----MTRSD--RPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
MAV_4882|M.avium_104 -MVCMSQTSGARPYRGVEAAERLATRRNRLLGAGLDLLGAEQQNIAAVTV
MMAR_0536|M.marinum_M ----------MRPYRGVEATERLAARRSQLLESGLELLGSSDRDIAELTV
MUL_1200|M.ulcerans_Agy99 ----------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTV
MSMEG_0612|M.smegmatis_MC2_155 -------MTPVRPYRGIEAADRLAQRRGQLLAAGLDLLGD---ENAEVTV
MAB_2494c|M.abscessus_ATCC_199 -----MSSPAGRSYSGLPADERLARRRQRLLEVGLDILGTPD-GSGDLTL
:
Mflv_0331|M.gilvum_PYR-GCK RAICAQSGLAARYFYESFTDKDVFVGAVFDRVIADIATTTQAAVAAAPPR
Mvan_0409|M.vanbaalenii_PYR-1 RAICAQSGLAARYFYESFADKDVFVGAVFDWVVADIAATTQAAVAAAPVR
TH_0801|M.thermoresistible__bu RAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAAAPRR
Rv0275c|M.tuberculosis_H37Rv RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAR
Mb0281c|M.bovis_AF2122/97 RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAR
MAV_4882|M.avium_104 RGVCRRAGLAARYFYESFTDKDQFVACVFDWVVAELAATTQAAVTAVPAH
MMAR_0536|M.marinum_M RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVPPP
MUL_1200|M.ulcerans_Agy99 RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVPPP
MSMEG_0612|M.smegmatis_MC2_155 RAVCQRAGLAARYFYESFGDKDAFVSEVYDWVIAEIAASTQAAVASVPLA
MAB_2494c|M.abscessus_ATCC_199 RTVCQRSGLAQRYFYESFADKDEYAAAIFDWAIEGLAATVEAEVAAAHPR
* :* .:**: ******* *** : . ::* .: :.:: :* *::.
Mflv_0331|M.gilvum_PYR-GCK EQSRQGMANIVRAISEDARVGRLLFNAHLDNPVVVRKRAESGALFALLSG
Mvan_0409|M.vanbaalenii_PYR-1 EQSRQGMANIVNTISDDIRVGRLLFNTRLDNPVVVRKRAESGALFALLSG
TH_0801|M.thermoresistible__bu DQTRAGMANIVRTVSEDPRVGRLLFSRHLSTATVVRKRAESGALFAMLSG
Rv0275c|M.tuberculosis_H37Rv EQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSG
Mb0281c|M.bovis_AF2122/97 EQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSG
MAV_4882|M.avium_104 EQTRAGMANIVRTITEDARVGRLLFSTQLADPVVVRKRAESSALFAMLSG
MMAR_0536|M.marinum_M EQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSG
MUL_1200|M.ulcerans_Agy99 EQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSG
MSMEG_0612|M.smegmatis_MC2_155 EQTTAAMTNIVRTIADDPRIGRLLFSAKLSNEVVVRKRVEGIGFFAGLLG
MAB_2494c|M.abscessus_ATCC_199 LQVRAGITSVVRAVSADRRIGQLLYSRHQVNPVLVRRRFDATAMFVSLFA
* .::.:*.:: * *:*:**:. : .:.*:* :. .:*. * .
Mflv_0331|M.gilvum_PYR-GCK QHAGSALRLERNDRITSAAHFVVGGVAQTLSAWLAGDLTFTEAQLAAQLG
Mvan_0409|M.vanbaalenii_PYR-1 QHAGTALQVEPNERIRAAAHFAVGGVAQTLSAWLAGDLAFTPEQLAGQLG
TH_0801|M.thermoresistible__bu QHVGSTMQLPENERIKATSHFVVGGVGQTIGAWLAGEVRLSPEALIDQLA
Rv0275c|M.tuberculosis_H37Rv QHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLA
Mb0281c|M.bovis_AF2122/97 QHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLA
MAV_4882|M.avium_104 QHVGDALRMPANDRIKAAAHFVVGGVAQTISAWLAGEVRLEPDQLVDQLA
MMAR_0536|M.marinum_M QHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLA
MUL_1200|M.ulcerans_Agy99 QHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLA
MSMEG_0612|M.smegmatis_MC2_155 QHTVDALRLPENDQLRATAHFAVGGVTQTISAWLGGEVSFTPDELVQQLR
MAB_2494c|M.abscessus_ATCC_199 QHLHDWFRRDDQGNLPVLAHFIVGGVGQAVTAWLHQEVTISEDELIEQLV
** :: : .: :** **** *:: **: :: : * **
Mflv_0331|M.gilvum_PYR-GCK ALIDQLADPALYRD---------------------------------
Mvan_0409|M.vanbaalenii_PYR-1 ALLDQLADPTLYRD---------------------------------
TH_0801|M.thermoresistible__bu SVIDQLAKPELFRAD--------------------------------
Rv0275c|M.tuberculosis_H37Rv ALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
Mb0281c|M.bovis_AF2122/97 ALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
MAV_4882|M.avium_104 ALLDELAEPALYRR--TETPAQS------------------------
MMAR_0536|M.marinum_M SLLDELSDPRLYGLRGTRAGATAASPAQ-------------------
MUL_1200|M.ulcerans_Agy99 SLLDELSDPRLYGLRGTRAGATAASPAQ-------------------
MSMEG_0612|M.smegmatis_MC2_155 SLLDALANLQSRK----------------------------------
MAB_2494c|M.abscessus_ATCC_199 DMLLAHGPAGSGQR---------------------------------
::