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MVTKQATGLYGGRTADERRAERRRRLLEAGLEVMASSGWAATTVREICKTAGLNTRYFYECFDGLDELLV AVFDWIIEDSIATAGSAMAAADKDSRSQVHAGVVGAVTALTADPRRARVIATEAMGSQRLTRRRMRLTHY MALMLGAARAEFDPEADPNYTAVQAEALAAGVAGTVLAWLDGRLRLEREELAEYTAQFVDQAMFTPLPVH NSVEH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1638 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2070c | - | 1e-26 | 33.16% (193) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2494c | - | 1e-25 | 35.90% (195) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 8e-28 | 34.54% (194) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4631 | - | 2e-28 | 35.38% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 4e-27 | 34.02% (194) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-07 | 22.22% (180) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3142 | - | 7e-27 | 34.36% (195) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4882 | - | 1e-25 | 33.51% (194) | FadD27 protein |
| M. smegmatis MC2 155 | MSMEG_1168 | - | 2e-25 | 37.37% (190) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 4e-29 | 37.11% (194) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_1200 | - | 4e-25 | 34.02% (194) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1244 | - | 5e-23 | 31.58% (190) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4631|M.gilvum_PYR-GCK -MGADATKVLRPTVVCQDGHVRTRSKRWGGRTGAERRAERRQRLIDAATE
MMAR_3142|M.marinum_M ---------------MFD--VRSRNTRWGGRTGAERRAERRQQLIEAATE
Mvan_1244|M.vanbaalenii_PYR-1 -------------MSSAASRPAATPTRWAGVPLTDRRAERRALLVDAAFR
Mb0281c|M.bovis_AF2122/97 ------------------MTRSD--RPYRGVEAAERLATRRRQLLSAGLD
Rv0275c|M.tuberculosis_H37Rv ------------------MTRSD--RPYRGVEAAERLATRRRQSLSAGLD
MAV_4882|M.avium_104 ---------------MVCMSQTSGARPYRGVEAAERLATRRNRLLGAGLD
MUL_1200|M.ulcerans_Agy99 ------------------------MRPYRGVEATERLATRRSQLLESGLE
TH_0801|M.thermoresistible__bu --------------MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLE
MAB_1638|M.abscessus_ATCC_1997 ------------------MVTKQATGLYGGRTADERRAERRRRLLEAGLE
MSMEG_1168|M.smegmatis_MC2_155 ----------------------MSQRSYAGQSAEERRRLRRARLLDAAMD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
** : .
Mflv_4631|M.gilvum_PYR-GCK IWSESG--WAAVTMRGVCAKTGLNDRYFYEDFKTRDELLVAAWDGVRNEM
MMAR_3142|M.marinum_M IWSESG--WAAVTMRGVCARTGLNDRYFYEDFKTREDLLVAAWDGVRNDM
Mvan_1244|M.vanbaalenii_PYR-1 LFGDGG--EQALSVRSVSREAGLNTRYFYESFTDTDDLLGAVYDRVSAEL
Mb0281c|M.bovis_AF2122/97 LLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAEL
Rv0275c|M.tuberculosis_H37Rv LLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAEL
MAV_4882|M.avium_104 LLGAEQQNIAAVTVRGVCRRAGLAARYFYESFTDKDQFVACVFDWVVAEL
MUL_1200|M.ulcerans_Agy99 LLGSSDRDIAELTVRGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDL
TH_0801|M.thermoresistible__bu LLGGEQRDPAELTVRAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDI
MAB_1638|M.abscessus_ATCC_1997 VMASSG--WAATTVREICKTAGLNTRYFYECFDGLDELLVAVFDWIIEDS
MSMEG_1168|M.smegmatis_MC2_155 AMCANA--WRAVTVDKLCASAGLNKRYFYENFTHLDSVAAAVIDDIAADV
MLBr_00815|M.leprae_Br4923 VFVDHG--YHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNL
: :. :*: :*: * .. . : :
Mflv_4631|M.gilvum_PYR-GCK LGEVSATLAERIGQPPMETIRVTIAAVVDRIAEDPGRAKILLAQHVGSSP
MMAR_3142|M.marinum_M LGEVSALFDERVDRPPIETITAAIAIVVDRIARDPGRAHILLAQHVGSSP
Mvan_1244|M.vanbaalenii_PYR-1 AEVVEAAMSG-AGASLPARTRAGMTAVLHFSSADPRRGRVLFTDAR-ANP
Mb0281c|M.bovis_AF2122/97 VATTQAAVTAVP---AREQTRAGMANIVRTITADARVGRLLFSTQLANAV
Rv0275c|M.tuberculosis_H37Rv VATTQAAVTAVP---AREQTRAGMANIVRTITADARVGRLLFSTQLANAV
MAV_4882|M.avium_104 AATTQAAVTAVP---AHEQTRAGMANIVRTITEDARVGRLLFSTQLADPV
MUL_1200|M.ulcerans_Agy99 ATTIQAAVATVP---PPEQARAGIAEIVRTIVGDARIGRLLFSTHLANPV
TH_0801|M.thermoresistible__bu AATTQAAVAAAP---RRDQTRAGMANIVRTVSEDPRVGRLLFSRHLSTAT
MAB_1638|M.abscessus_ATCC_1997 IATAGSAMAAADK-DSRSQVHAGVVGAVTALTADPRRARVIATEAMGSQR
MSMEG_1168|M.smegmatis_MC2_155 RTAALTALAGAASRPLDEQAAVAMDALVHILLDDPRRARVLLGGVASSPS
MLBr_00815|M.leprae_Br4923 VSSVQQALRTTTN--NRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEP
. . : . * :::
Mflv_4631|M.gilvum_PYR-GCK LQDRRAVALQ-EATHLVIAASEPHLRPEADETALRMDTLVAVGGFVELIT
MMAR_3142|M.marinum_M LQDRRAVALQ-EATQLVVEASRPHLREDADETALRMDTLVAVGGFVEVIT
Mvan_1244|M.vanbaalenii_PYR-1 VLTQRRAATQ-DLLREAVLTEGWRLHPDSDPTAAMVGAAMYTGAMAELAQ
Mb0281c|M.bovis_AF2122/97 ITRKRAESS--ALFAMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTIS
Rv0275c|M.tuberculosis_H37Rv ITRKRAESS--ALFAMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTIS
MAV_4882|M.avium_104 VVRKRAESS--ALFAMLSGQHVGDALRMPANDRIKAAAHFVVGGVAQTIS
MUL_1200|M.ulcerans_Agy99 VVRKRTESS--ALFAMLSGQHAGDALRIPANDRIKVGAHFIVGGVAQTIS
TH_0801|M.thermoresistible__bu VVRKRAESG--ALFAMLSGQHVGSTMQLPENERIKATSHFVVGGVGQTIG
MAB_1638|M.abscessus_ATCC_1997 LTRRRMRLT--HYMALMLGAARAEFDPEADPNYTAVQAEALAAGVAGTVL
MSMEG_1168|M.smegmatis_MC2_155 LQQHREAVMRGLTKVLVTHARTVHGVELETDPLSQVAPAFLVGGTADAIL
MLBr_00815|M.leprae_Br4923 RVAAQVRVATESCIDAVFALISADSR--LDPHRARMVAVGLVGISVDCAR
: . ..
Mflv_4631|M.gilvum_PYR-GCK AWHAGLLDVIQGEIVEHTSRLAETLAERYLVDDAGL--------------
MMAR_3142|M.marinum_M AWHSGLLAVTEKEVVAHTSRLAETLAQRYVVSG-----------------
Mvan_1244|M.vanbaalenii_PYR-1 QWLAGHLGDDLDAVVGYALRLVLR--------------------------
Mb0281c|M.bovis_AF2122/97 AWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPP
Rv0275c|M.tuberculosis_H37Rv AWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPP
MAV_4882|M.avium_104 AWLAGEVRLEPDQLVDQLAALLDELAEPALYRR--TETPAQS--------
MUL_1200|M.ulcerans_Agy99 AWIEGDVELEPGQLVDQLASLLDELSDPRLYGLRGTRAGATAASPAQ---
TH_0801|M.thermoresistible__bu AWLAGEVRLSPEALIDQLASVIDQLAKPELFRAD----------------
MAB_1638|M.abscessus_ATCC_1997 AWLDGRLRLEREELAEYTAQFVDQAMFTPLPVHNSVEH------------
MSMEG_1168|M.smegmatis_MC2_155 AFVDGRAKLSREQLVDSLATLWLITGNGATQTARARHEAL----------
MLBr_00815|M.leprae_Br4923 YWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----------------
: .
Mflv_4631|M.gilvum_PYR-GCK ----------------
MMAR_3142|M.marinum_M ----------------
Mvan_1244|M.vanbaalenii_PYR-1 ----------------
Mb0281c|M.bovis_AF2122/97 EVAGQPPSSARPARRS
Rv0275c|M.tuberculosis_H37Rv EVAGQPPSSARPARRS
MAV_4882|M.avium_104 ----------------
MUL_1200|M.ulcerans_Agy99 ----------------
TH_0801|M.thermoresistible__bu ----------------
MAB_1638|M.abscessus_ATCC_1997 ----------------
MSMEG_1168|M.smegmatis_MC2_155 ----------------
MLBr_00815|M.leprae_Br4923 ----------------