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MSDRSYQPTVVGLRAFVAIARKRHFGSAAGELGVSQPSLSQALSMLEEGLGVRLVERNTRKVLLTPEGDA LLEKAISALNAVDEFTSAASGVRDPFAQTLRLGLIPTVAPYVLPMVLSGLSREFPEMSLRVTEDQTHRLL RSLSDGTLDVAVMALPVQTQGMAEIPMYREDFVLALPSGHPLAGSKNVEPADLADMPLLLLDEGHCLRDQ ALEVCQLAGVRPDLGHTRAASLATAVQCVEGGLGVTLIPGTAVTAETASGGLATATFAAPVPGRRIGLVY RAISAREDAYRRLAELLTRLVSAVHPVTADAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4409 | - | - | 100% (312) | hydrogen peroxide-inducible genes activator |
| M. abscessus ATCC 19977 | MAB_0993c | - | 9e-25 | 29.11% (292) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2707 | - | 8e-24 | 27.20% (239) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 3e-20 | 26.58% (316) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 1e-27 | 34.17% (278) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 3e-20 | 26.58% (316) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 1e-101 | 58.63% (307) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 1e-103 | 62.58% (302) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_2838 | - | 1e-104 | 62.54% (307) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_5654 | - | 2e-31 | 34.31% (239) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-11 | 25.66% (265) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 1e-101 | 61.26% (302) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 1e-25 | 29.80% (245) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
MAV_2838|M.avium_104 --------MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQA
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MAB_4409|M.abscessus_ATCC_1997 --------MSDRSYQPTVVGLRAFVAIARKRHFGSAAGELGVSQPSLSQA
Mflv_1346|M.gilvum_PYR-GCK ---------------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQ
MSMEG_5654|M.smegmatis_MC2_155 -----------------MRHLRCFVVLAEELHFGRAAQRLHVAQPALSQL
Mvan_1027|M.vanbaalenii_PYR-1 --------------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLSRQ
Mb2303c|M.bovis_AF2122/97 --------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRR
Rv2282c|M.tuberculosis_H37Rv --------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRR
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
: : * .:.. : ** * : * .:*
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
MAV_2838|M.avium_104 LAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGS
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MAB_4409|M.abscessus_ATCC_1997 LSMLEEGLGVRLVERNTRKVLLTPEGDALLEKAISALNAVDEFTSAASGV
Mflv_1346|M.gilvum_PYR-GCK IRQLEREVGADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRI
MSMEG_5654|M.smegmatis_MC2_155 IQRVERELGAQLFLRTRRTVSLTEAGQTLLPEARRILRDADRVTQAVRAV
Mvan_1027|M.vanbaalenii_PYR-1 VQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVKRI
Mb2303c|M.bovis_AF2122/97 LASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSL
Rv2282c|M.tuberculosis_H37Rv LASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSL
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
: :* :. * * * :* * . :
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLP----TLTLRVV-EDQTE
MAV_2838|M.avium_104 ADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRP----GLTLRVT-EDQTE
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLP----TLTVRVI-EDQTE
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLP----TLTVRVI-EDQTE
MAB_4409|M.abscessus_ATCC_1997 RDPFAQTLRLGLIPTVAPYVLPMVLSGLSREFP----EMSLRVT-EDQTH
Mflv_1346|M.gilvum_PYR-GCK GTGAEGRLVVGCVGSATYSLLPRLVRELRAALP----AVDLRVRGEMLAP
MSMEG_5654|M.smegmatis_MC2_155 HRGETGSVTIGFVGSAADDVLPRLVAAHRRHHP----GVSIRLE-EGTTA
Mvan_1027|M.vanbaalenii_PYR-1 PAGDLGTVVVGFTAASAHAVLPRLLERARERLP----DVKLDLR-EMVTA
Mb2303c|M.bovis_AF2122/97 RTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSE
Rv2282c|M.tuberculosis_H37Rv RTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSE
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYP----STSFTLR-QLYPD
. : : : : .
MLBr_02041|M.leprae_Br4923 HLLTALREGALDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKR-
MAV_2838|M.avium_104 RLLAVLREGALDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKR-
MMAR_2756|M.marinum_M RLLTALREGSLDTALIALPADYGGLTEIPIYEEDFVLALPPGHPMADRH-
MUL_2998|M.ulcerans_Agy99 RLLTALREGSLDTALIALPADYGGLTEIPIYEEDFVLALPPGHPMADRH-
MAB_4409|M.abscessus_ATCC_1997 RLLRSLSDGTLDVAVMALPVQTQGMAEIPMYREDFVLALPSGHPLAGSK-
Mflv_1346|M.gilvum_PYR-GCK EQLAALHAKDIDLALMRPPVDDPALTAVSLRRDRLLVALPAGHRCADRD-
MSMEG_5654|M.smegmatis_MC2_155 QQLEWLRDQRITVGLGRTPIDDPAVSTVVLARESLVLAVPDSHALSGAE-
Mvan_1027|M.vanbaalenii_PYR-1 AQIEGLMTGELDLGMARPPLKRPGLVSRPLLHEQLLAALPEGHPLADMTR
Mb2303c|M.bovis_AF2122/97 HAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSR
Rv2282c|M.tuberculosis_H37Rv HAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSR
TH_3504|M.thermoresistible__bu ALTDAVFDGTVQLGLRRGVVPTPELATAVIGYHRVRVAFVDSHPLAARE-
: .. : : . . .. .* :
MLBr_02041|M.leprae_Br4923 RVPTTALAQLPLLLLDEG--HCLRDQTLDICRK---SGVQAELANTRAAS
MAV_2838|M.avium_104 RVPATALADLPLLLLDEG--HCLRDQALDVCHK---AGVRAELANTRAAS
MMAR_2756|M.marinum_M GVPVAALSELPLLLLDEG--HCLRDQALDVCQN---AGVRAELADTRAAS
MUL_2998|M.ulcerans_Agy99 GVPVAALSELPLLLLDEG--HCLRDQALDVCQN---AGVRAEHADTRADS
MAB_4409|M.abscessus_ATCC_1997 NVEPADLADMPLLLLDEG--HCLRDQALEVCQL---AGVRPDLGHTRAAS
Mflv_1346|M.gilvum_PYR-GCK EVSLADLRDEDFISHAGGGRSRMSALLAALCAD---AGFSPRIRD-EVDE
MSMEG_5654|M.smegmatis_MC2_155 SAELAGLAEEPFIMFPRHLGPGLYDIIHSACAA---AGFTPSVVY-ETVR
Mvan_1027|M.vanbaalenii_PYR-1 ELTLIDLDGQDFVMYSPVQARYFNELLISTFTI---AGTTPRYVQ-YVTQ
Mb2303c|M.bovis_AF2122/97 VVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLELSS
Rv2282c|M.tuberculosis_H37Rv VVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLELSS
TH_3504|M.thermoresistible__bu SVDITELAREQVALWAPPGTSYYSDFLMGACRR---AGFEPDYVVSRVQG
* . .
MLBr_02041|M.leprae_Br4923 LATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFR
MAV_2838|M.avium_104 LATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFR
MMAR_2756|M.marinum_M LATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRRIGLVYR
MUL_2998|M.ulcerans_Agy99 LATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLVYR
MAB_4409|M.abscessus_ATCC_1997 LATAVQCVEGGLGVTLIPGTAVTAETASGGLATATFAAPVPGRRIGLVYR
Mflv_1346|M.gilvum_PYR-GCK TSTLVTLVAGGLGVALVPEPTAALEI-GGVTYRPLAAKAGATIELLAVYR
MSMEG_5654|M.smegmatis_MC2_155 MQTIVGLVSGGLGVALVPESVRNLGR-KGVRYVHLADAP-PAIELSMMWR
Mvan_1027|M.vanbaalenii_PYR-1 VHTMLVLVRSGIGIALVPASAATLHP-EGVVFRTIGAFRERPVELDAVWR
Mb2303c|M.bovis_AF2122/97 AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWV
Rv2282c|M.tuberculosis_H37Rv AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWV
TH_3504|M.thermoresistible__bu AATVAAPLTTG-GIAFVTAAAGPTMN---GRVQVVDLTPPLLVPVQALWQ
: : * * : :. . : :
MLBr_02041|M.leprae_Br4923 SASGRSASYRQIAKIIGELISTEHHVRLVA-
MAV_2838|M.avium_104 SSSGRDDSYRELAGLIGELISSQHQVRLVK-
MMAR_2756|M.marinum_M ASSGRDEAYRQLAAIMGESISNEQQVRLVN-
MUL_2998|M.ulcerans_Agy99 ASSGRDEAYRQLAAIMGESISNEQQVRLVN-
MAB_4409|M.abscessus_ATCC_1997 AISAREDAYRRLAELLTRLVSAVHPVTADAA
Mflv_1346|M.gilvum_PYR-GCK SADASPLTAKVVDVLRATV------------
MSMEG_5654|M.smegmatis_MC2_155 NDCESPHLQPLRKTARHL-------------
Mvan_1027|M.vanbaalenii_PYR-1 GDSTNPALLRVLKDVLPQQEWTT--------
Mb2303c|M.bovis_AF2122/97 G--GRTPPAGAIRDLLSHITSRST-------
Rv2282c|M.tuberculosis_H37Rv G--GRTPPAGAIRDLLSHITSRST-------
TH_3504|M.thermoresistible__bu RHTLSAIRDRILEGLG---------------