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SGQRQRVSRAESQQRTREELLDAAEELFLANGLGGTTVTKIAEAAGRTVGAIYSNFSSKENLCAEVLLRC YMRTFSEVAGRLIQSASSVDEQITELAQWSASLGGDEGLVALAAEYALAIHKDQVQLAVSQGHIEMGRGL LAAVLANALPDDVSDDDRDAALTAVLATAVGLALGRTLGTIDEQQYVDLLTRTLRLWIADLRRSAHISS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0145c | - | - | 100% (210) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0138 | - | 7e-24 | 33.33% (198) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3437c | - | 2e-16 | 32.23% (211) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 2e-08 | 25.43% (173) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 9e-13 | 31.02% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 7e-08 | 24.86% (173) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 7e-05 | 38.46% (65) | putative TetR/AcrR-family transcriptional regulator |
| M. marinum M | MMAR_0500 | - | 2e-06 | 26.87% (201) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1611 | - | 3e-11 | 30.30% (198) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0148 | - | 9e-14 | 49.37% (79) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 2e-07 | 44.44% (54) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1163 | - | 6e-07 | 27.36% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 1e-12 | 29.72% (212) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0500|M.marinum_M --------------------------MAGGTKRLPRAIREQQMLDAAVQM
MUL_1163|M.ulcerans_Agy99 --------------------------MAGGTKRLPRAIREQQMLDAAVQM
Mflv_2460|M.gilvum_PYR-GCK -------------------------MVERWTRERRLEHTRSVLLDAAEEV
Mvan_4194|M.vanbaalenii_PYR-1 -------------------------MAERWTRERRLEHTRSVLLDAAEEV
Mb0310|M.bovis_AF2122/97 ------------------------MGVPAKKKQQQGERSRESILDATERL
Rv0302|M.tuberculosis_H37Rv ------------------------MGVPAKKKQQQGERSRESILDATERL
MAB_0145c|M.abscessus_ATCC_199 ----------------------MSGQRQRVSRAESQQRTREELLDAAEEL
MAV_1611|M.avium_104 -------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAKV
MSMEG_0148|M.smegmatis_MC2_155 -----------------------MVPRKRLTRAEARAQTRRRLLDAAAET
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
MLBr_00316|M.leprae_Br4923 -------------MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEA
. :*..: .
MMAR_0500|M.marinum_M FSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFIDA
MUL_1163|M.ulcerans_Agy99 FSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFIDA
Mflv_2460|M.gilvum_PYR-GCK FAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFDN
Mvan_4194|M.vanbaalenii_PYR-1 FAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFDN
Mb0310|M.bovis_AF2122/97 MATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAA
Rv0302|M.tuberculosis_H37Rv MATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAA
MAB_0145c|M.abscessus_ATCC_199 FLANGLGGTTVTKIAEAAGRTVGAIYSNFSSKENLCAEVLLRCYMRTFSE
MAV_1611|M.avium_104 FAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQQ
MSMEG_0148|M.smegmatis_MC2_155 FARKGYDAASVEEIAEAAGYSVGAVYSNFSSKEQLFSELRSERAALRLDE
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
MLBr_00316|M.leprae_Br4923 FATEGLS-VPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDD
: .* . : * . .* : :*: :
MMAR_0500|M.marinum_M VRADIDLSQSPKDLLRNAIVSFLRYIDQNQ-----ASWIVMYTQAVSSQA
MUL_1163|M.ulcerans_Agy99 VRADIDLSQSPKDLLRNAIVSFLRYIDQNQ-----ASWIVMYTQAVSSQA
Mflv_2460|M.gilvum_PYR-GCK FAEVMSSASRVGADELDEIAERWRQLSIDRGAEHAALGLEFTLYLLRNPE
Mvan_4194|M.vanbaalenii_PYR-1 FAEVMASASRVGAHELDEIAERWRQLSIDRGADHAALGLEFTLYLLRNPD
Mb0310|M.bovis_AF2122/97 IPTWDEAHGPVEQRSERQLTELVSLQSQHP--DFLRLFYLLSMERSQDPV
Rv0302|M.tuberculosis_H37Rv IPTWDEAHGPVEQRSERQLTELVSLQSQHP--DFLRLFYLLSMERSQDPA
MAB_0145c|M.abscessus_ATCC_199 VAGRLIQSASSVDEQITELAQWSASLGGDE--GLVALAAEYALAIHKDQV
MAV_1611|M.avium_104 IAIALDRSAGDTTAAAREVSRSVLDSVRDHS-DYYVLLVEYWLRAQRDPQ
MSMEG_0148|M.smegmatis_MC2_155 VADALRSAQGDPGGPFAKLSRQLVEVADKN-IEVAALHTEFWLHAIRNPG
TH_4015|M.thermoresistible__bu VRTDAGTEPKNPYERILRANRTYLEAYRAN----RAIMIVWEQVASLNEH
MLBr_00316|M.leprae_Br4923 GYVLLKSAGPGEALFTYLRSLVLHWGATDR-------GLVDALAGAGGID
.
MMAR_0500|M.marinum_M FAQTVREGR----EQIVELVAGMLRAGTRSPRSDAEID----MMAAALVG
MUL_1163|M.ulcerans_Agy99 FAQTVREGR----EQIVELVAGMLRAGTRSPRSDAEID----MMAAALVG
Mflv_2460|M.gilvum_PYR-GCK ARERVEAKR----AEVVDQLAEFIVEGMSQLGATLLIEPSTFARALVATS
Mvan_4194|M.vanbaalenii_PYR-1 ARERVAAKR----AEVVDQLAKFINEGMTRLGASLLISPLTFAQALVATS
Mb0310|M.bovis_AF2122/97 VAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVA--ELTAFAVALS
Rv0302|M.tuberculosis_H37Rv VAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVA--ELTAFAVALS
MAB_0145c|M.abscessus_ATCC_199 QLAVSQGHIEMGRGLLAAVLANALPDDVSDDDRDAALTAVLATAVGLALG
MAV_1611|M.avium_104 LRERLIERR-----RAAADQALHIVESTDTVPGDRRLT--DIAQLVVTLN
MSMEG_0148|M.smegmatis_MC2_155 AMDVLAESVGQTLQSLTGIAADLLAEHNVDQSVVRPET---FAVSLLALH
TH_4015|M.thermoresistible__bu VEQLRREYS----DRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGML
MLBr_00316|M.leprae_Br4923 ILGVAPDAE----DAFLTILSDLLYAAQYAGTARTDVG----VREVKSIL
:
MMAR_0500|M.marinum_M AGEAVANRLSAGDTDVDEAAEMMIDLFWRGLKGAPSDREIGSNFAAG
MUL_1163|M.ulcerans_Agy99 AGEAVANRLSAGDTDVDEAAEMMIDLLWRGLKGAPSDREIGSNFAAG
Mflv_2460|M.gilvum_PYR-GCK DSVVLGSQLD----AVD-LYRPMVEMYVSVIKLPD------------
Mvan_4194|M.vanbaalenii_PYR-1 DSVVLASQLD----DID-LYRPVVEMYTSVIKLPD------------
Mb0310|M.bovis_AF2122/97 DGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET---------
Rv0302|M.tuberculosis_H37Rv DGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET---------
MAB_0145c|M.abscessus_ATCC_199 RTLGTIDEQQ----YVDLLTRTLRLWIADLRRSAHISS---------
MAV_1611|M.avium_104 LGVAMEEVLRPGTINPDLLAQLITALLESIPV---------------
MSMEG_0148|M.smegmatis_MC2_155 QGLIRQRRTNPSWVPEELFGQLLSWLLAGMPKLPAH-----------
TH_4015|M.thermoresistible__bu SNFAYRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA---
MLBr_00316|M.leprae_Br4923 VGCQAMEAYN------SALAERVTDVVVDGLRAAR------------
. . :