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ITVFLVDDHEVVRRGLADLLEEEADFSVIGQASSVAEAMARIPALQPDIAVLDIRLPDGNGVELCRELRS KLPNLNCLMLTSFTDEHAMLDAIMAGAGGYVIKDIKGMELISAVRTVGAGRSLLDNRAAAALMNRLRAAA DNPSPLAGLTAQERTLLELIGEGLTNRQIAERMFLAEKTVKNYVSRLLTKLDLERRTQVAVLATKLAREN QGLHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3891c | - | - | 100% (216) | LuxR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1522 | - | 5e-32 | 35.10% (208) | putative two-component system response regulator LuxR |
| M. abscessus ATCC 19977 | MAB_3714c | - | 4e-28 | 35.47% (203) | two-component LuxR family response regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 3e-83 | 71.77% (209) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3847 | - | 3e-81 | 69.86% (209) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 3e-83 | 71.77% (209) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_00773 | mtrA | 1e-11 | 33.33% (114) | putative two-component response regulator |
| M. marinum M | MMAR_1516 | devR | 5e-84 | 69.77% (215) | two-component transcriptional regulatory protein DevR |
| M. avium 104 | MAV_4109 | - | 4e-81 | 70.48% (210) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_5244 | - | 3e-84 | 72.04% (211) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 8e-84 | 72.25% (209) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 3e-84 | 69.77% (215) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_2548 | - | 3e-84 | 71.70% (212) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3847|M.gilvum_PYR-GCK ----MVKVFLVDDHEVVRRGLIDLLGSD-PELDVVGEAGSVSEALTRVPT
Mvan_2548|M.vanbaalenii_PYR-1 ----MVKVFLVDDHEVVRRGLIDLLSSD-PELDVVGEAGSVAEALARIPA
MSMEG_5244|M.smegmatis_MC2_155 ----MIRVFLVDDHEVVRRGLIDLLSAD-PELDVIGEADSVSQALARIPA
TH_2159|M.thermoresistible__bu ----MVSVFLVDDHEVVRRGLIDLLDSD-PDLEVVGEAGTVAQAMARIPA
Mb3157c|M.bovis_AF2122/97 ----MVKVFLVDDHEVVRRGLVDLLGAD-PELDVVGEAGSVAEAMARVPA
Rv3133c|M.tuberculosis_H37Rv ----MVKVFLVDDHEVVRRGLVDLLGAD-PELDVVGEAGSVAEAMARVPA
MMAR_1516|M.marinum_M ----MVTVFLVDDHEVVRRGLIDLLDAD-PQLDVVGEAGSVSEAMARIPA
MUL_2423|M.ulcerans_Agy99 ----MVTVFLVDDHEVVRRGLIDLLDAD-PQLDVVGEAGSVSEAMARIPA
MAV_4109|M.avium_104 ----MVKVFLVDDHEVVRRGLCDLLSSD-PDLRIVGEAGTVAEAKARIPA
MAB_3891c|M.abscessus_ATCC_199 ----MITVFLVDDHEVVRRGLADLLEEE-ADFSVIGQASSVAEAMARIPA
MLBr_00773|M.leprae_Br4923 MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDG---TQALTAVRE
:::***. : . * :* : : ::*:. ::* : :
Mflv_3847|M.gilvum_PYR-GCK AQPDVAVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDEAMLDAIL
Mvan_2548|M.vanbaalenii_PYR-1 LQPDVAVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDEAMLDAIL
MSMEG_5244|M.smegmatis_MC2_155 AQPDVAVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDEAMLDAIL
TH_2159|M.thermoresistible__bu AQPDVAVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQAMLDAIL
Mb3157c|M.bovis_AF2122/97 ARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAIL
Rv3133c|M.tuberculosis_H37Rv ARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAIL
MMAR_1516|M.marinum_M ANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAIL
MUL_2423|M.ulcerans_Agy99 ANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAIL
MAV_4109|M.avium_104 ARPDVAVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDEAMLEAIL
MAB_3891c|M.abscessus_ATCC_199 LQPDIAVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAMLDAIM
MLBr_00773|M.leprae_Br4923 LRPDLVLLDLMLPGMNGIDVCRVLRADS-GVPIVMLTAKTDTVDVVLGLE
.**:.:**: **. :*:::** * : .: ::**: *. :: .:
Mflv_3847|M.gilvum_PYR-GCK AGASGYVVKDIKGMELARAIKEVGSGR----SLLDNRAAAALMAKLRGEG
Mvan_2548|M.vanbaalenii_PYR-1 AGASGYVVKDIKGMELAQAIKDVGSGR----SLLDNRAAAALMARLRGEG
MSMEG_5244|M.smegmatis_MC2_155 AGASGYVVKDIKGMELAQAIKDVGAGK----SLLDNRAATALMSKLRGDA
TH_2159|M.thermoresistible__bu AGASGYVVKDIKGMELAQAIKDVGAGR----SLLDNRAAEALMAKLRGAD
Mb3157c|M.bovis_AF2122/97 AGASGYVVKDIKGMELARAVKDVGAGR----SLLDNRAAAALMAKLRGAA
Rv3133c|M.tuberculosis_H37Rv AGASGYVVKDIKGMELARAVKDVGAGR----SLLDNRAAAALMAKLRGAA
MMAR_1516|M.marinum_M AGASGYVVKDIKGMELARAIKEVGAGR----SLLDNRAAAALMSRLRGVV
MUL_2423|M.ulcerans_Agy99 AGASGYVVKDIKGMELARAIKEVGAGR----SLLDNRAAAALMSRLRGVV
MAV_4109|M.avium_104 AGASGFVIKDIKGMELARAIKDVGAGK----SLLDNRAAAALMAKLRGSA
MAB_3891c|M.abscessus_ATCC_199 AGAGGYVIKDIKGMELISAVRTVGAGR----SLLDNRAAAALMNRLRAAA
MLBr_00773|M.leprae_Br4923 SGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVDIDVPAHKVT
:**..:::* :* ** :: . : : . * : :
Mflv_3847|M.gilvum_PYR-GCK ERTDPLSGLTDQERVLLDLLGEG---------LTNKQIAARMFLAEKTVK
Mvan_2548|M.vanbaalenii_PYR-1 ERTDPLSGLTEQERVLLGLLGEG---------LTNKQIAARMFLAEKTVK
MSMEG_5244|M.smegmatis_MC2_155 ERSDPLSGLTQQERVLLDLLGEG---------LTNKQIAARMFLAEKTVK
TH_2159|M.thermoresistible__bu HQPDPLAGLSDQERVLLSLIGEG---------LTNKQIAARMFLAEKTVK
Mb3157c|M.bovis_AF2122/97 EKQDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
Rv3133c|M.tuberculosis_H37Rv EKQDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
MMAR_1516|M.marinum_M ERPDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
MUL_2423|M.ulcerans_Agy99 ERPDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
MAV_4109|M.avium_104 AQADPLSGLTEQERTLLGLLSEG---------LTNRQIAARMFLAEKTVK
MAB_3891c|M.abscessus_ATCC_199 DNPSPLAGLTAQERTLLELIGEG---------LTNRQIAERMFLAEKTVK
MLBr_00773|M.leprae_Br4923 RNGEHIS-LTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVN
. . :: *: * ** :.. * :: . * : *:
Mflv_3847|M.gilvum_PYR-GCK NYVSRLLAKLGMERRTQAAVFISKLDRGHGAGNA------
Mvan_2548|M.vanbaalenii_PYR-1 NYVSRLLAKLGMERRTQAAVFVSKLERHHRPDGE------
MSMEG_5244|M.smegmatis_MC2_155 NYVSRLLAKLGMERRTQAAVFASKLDRRN-----------
TH_2159|M.thermoresistible__bu NYVSRLLAKLGMERRTQAAVFVSKLDRPIDPRG-------
Mb3157c|M.bovis_AF2122/97 NYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP-----
Rv3133c|M.tuberculosis_H37Rv NYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP-----
MMAR_1516|M.marinum_M NYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR------
MUL_2423|M.ulcerans_Agy99 NYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR------
MAV_4109|M.avium_104 NYVSRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
MAB_3891c|M.abscessus_ATCC_199 NYVSRLLTKLDLERRTQVAVLATKLARENQGLHG------
MLBr_00773|M.leprae_Br4923 VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP-------
:*.** :*: : .. ..*: .