For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRVAIIGAGIGGLTAAAALRANDIDVIVYEKAHELREVGAGVVIANNGLRALDEVGLGDRVRAVGTQIRR TLWHTWQGESVPVPPAWPAVSPDRPVTSLPVHRGELQHALLGALPAGTVQLGRPCQDIVETADEVRIIFA DGSEERADVAVGADGIHSAVQRVVADPVELSSDGIMAYRGLIPVERLDGVIDLNSMQMWLGPGRSFLIYP VSRGRLLNVVAFTPSNLDAEESWTAPGDVAELSAEFAGWDQPVQRVAGAMTETFRWGLYDRKPLNRWTTD RIALLGDAAHPMTPHLGQGANMSIEDAVVLATVLAGASATEVPRRLSLYESLRRDRTSRVQRNARQSGRV YRSVDLTAQQQAAQLTEILADNWIPDYDAAATAGTALATL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3330 | - | - | 100% (390) | putative salicylate hydroxylase |
| M. abscessus ATCC 19977 | MAB_0288 | - | 9e-49 | 34.75% (377) | putative monooxygenase (salicylate/ hydroxybenzoate hydroxylase |
| M. abscessus ATCC 19977 | MAB_1601c | - | 1e-37 | 30.88% (353) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 3e-13 | 26.16% (344) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 5e-43 | 32.99% (388) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1260 | - | 7e-16 | 24.92% (325) | hypothetical protein Rv1260 |
| M. leprae Br4923 | MLBr_02276 | - | 6e-06 | 24.78% (339) | putative FAD-linked oxidoreductase |
| M. marinum M | MMAR_4944 | - | 6e-38 | 31.78% (365) | oxidoreductase |
| M. avium 104 | MAV_4429 | - | 4e-26 | 27.79% (385) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3841 | - | 5e-41 | 34.47% (351) | hypothetical protein MSMEG_3841 |
| M. thermoresistible (build 8) | TH_0968 | - | 2e-14 | 26.12% (356) | 3-(3-hydroxy-phenyl)propionate hydroxylase |
| M. ulcerans Agy99 | MUL_1770 | - | 7e-21 | 25.85% (352) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 1e-39 | 31.63% (392) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0590c|M.bovis_AF2122/97 ------MK-VAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYMID
Rv1260|M.tuberculosis_H37Rv ------MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAID
MUL_1770|M.ulcerans_Agy99 ----MAKPIVLISGAGIAGPALAFWLTHSGYQVVVTELADDIRPGGQTVD
MAB_3330|M.abscessus_ATCC_1997 -------MRVAIIGAGIGGLTAAAALRANDIDVIVYEKAHELREVGAGVV
MSMEG_3841|M.smegmatis_MC2_155 ---MSITTTVAIAGAGIGGLTAALALQQRGFEVVVLESAHELRPLGVGIN
Mflv_2621|M.gilvum_PYR-GCK -----MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG-AGSGIS
Mvan_3960|M.vanbaalenii_PYR-1 -----MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLT-SGAGIS
MMAR_4944|M.marinum_M -------MKAVIIGAGIGGMSAAIALRQIGIDTEVYERVTENKPVGAAIS
MAV_4429|M.avium_104 MVGDARPLRVLVVGAGVAGISVARGLLRDGHDVTVFERRPRLAAAGGAVT
TH_0968|M.thermoresistible__bu ---MTERVDVVIVGAGPSGLTLANILGLQGVRTLVVEERDTLIDYPRGVG
MLBr_02276|M.leprae_Br4923 -MRVETSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDKACGDG
: **. .* : * . : :
Mb0590c|M.bovis_AF2122/97 FWGVGYQVAKRMGITDQIAAAGYHMEHVRSVGPTGKVKADLGVDVFRRMV
Rv1260|M.tuberculosis_H37Rv VRGPALDVLERMGL---LAAAQEHKTRIRGASFVDRDGNELFRDTESTPT
MUL_1770|M.ulcerans_Agy99 LRGAGRLVIERMGLLEQMRQRSLRQRGIAWIRADGRRRAEMPVEAFHGNG
MAB_3330|M.abscessus_ATCC_1997 IANNGLRALDEVGLGDRVRAVGTQIRRTLWHTWQGES---VPVPPAWPAV
MSMEG_3841|M.smegmatis_MC2_155 LLPHAVRELDHLGLGDAVGDASVAPTAIRFYSADGTL---LFTEPRGLAA
Mflv_2621|M.gilvum_PYR-GCK LWPNALAALDQIGLGDSVRDAGGRVTAGAIRWRDGTW---VRRPSVRRIV
Mvan_3960|M.vanbaalenii_PYR-1 IWPNALAALDQIGLGDNVRQAGGRVTAGAIRWRDGTW---LRRPSAQRIV
MMAR_4944|M.marinum_M VWSNGVKCLNYLGLEQQTARLGGIVETMSYAEAHSGET--MCRISMQPLI
MAV_4429|M.avium_104 VWSNGETVLRQLGV--EMDGAGRQLSSVGAVTSTGRP---LATLDVTAMA
TH_0968|M.thermoresistible__bu LDDEALRTFQSIGLVDRILPHTVPNQILRFFDAKRRLLAEMAPP-DARFG
MLBr_02276|M.leprae_Br4923 LTPRAVAELKRLGLDDWLNTR-IRHRGLRMSGFGGEVEVDWPGPSFPSTS
. . :*:
Mb0590c|M.bovis_AF2122/97 GDDFTS----LPRGDLAAAIYT---TIEDQVETIFDDSIATIDEHRDG--
Rv1260|M.tuberculosis_H37Rv GGPVNSPDIELLRDDLVELLYG---ATQPSVEYLFDDSISTLQDDGDS--
MUL_1770|M.ulcerans_Agy99 ----PVSELEILRGDLAAVLYR---ATAAGTDYRFGTRITDLAPSGDA--
MAB_3330|M.abscessus_ATCC_1997 SPDRPVTSLPVHRGELQHALLG----ALPAGTVQLGRPCQDIVETADE--
MSMEG_3841|M.smegmatis_MC2_155 GDTHP--QLSIHRGRLQMLLLAAVRERLGADAVRTGARVSGFHDDGSR--
Mflv_2621|M.gilvum_PYR-GCK DALGEP-LVVVRRSRLTDILRE----ALPAGTVRTGLAATRVSVGASS--
Mvan_3960|M.vanbaalenii_PYR-1 HALGEP-LVVVRRSALTEILLD----ALPPDTVQTGLSATALSIAAAT--
MMAR_4944|M.marinum_M EQVGQR-PYPIARAELQQMLME----AYGIDEIHFGMKMVEVANRDGA--
MAV_4429|M.avium_104 RRLGAPVRMVPRRVLLERLLDG-----FPTGRIHCDRRAVALATSRDG--
TH_0968|M.thermoresistible__bu WPKRNGFVQPMVDAELYAGLDR-----FDHVEVRFGHRMQNCVEASDAGE
MLBr_02276|M.leprae_Br4923 SAVPR----LELDDRIRKVAEN------SGARMLLGTKAVSVYHDSSR--
: .
Mb0590c|M.bovis_AF2122/97 --VRLTFERTA-PRDFDLVIGADGLHSNVRRLVFG-PERDFEHYLGCKVA
Rv1260|M.tuberculosis_H37Rv --VRVTFERAA-AREFDLVIGADGLHSNVRRLVFG-PEEQFVKRLGTHAA
MUL_1770|M.ulcerans_Agy99 --VQARLSDGT-TVRADLVVGADGPHSGVRRLAFG-PEEQFARPLGGYNA
MAB_3330|M.abscessus_ATCC_1997 --VRIIFADGS-EERADVAVGADGIHSAVQRVVAD-PVELSSDGIMAYRG
MSMEG_3841|M.smegmatis_MC2_155 --VVVRTDAG--DVRADVLVGADGIGSVVRAALHPGPDPLRFSGITMFRG
Mflv_2621|M.gilvum_PYR-GCK --VRITLSDGE-VRESDAVVGADGVNSVLARTLNG-PLRTRYVGYTAWRG
Mvan_3960|M.vanbaalenii_PYR-1 --ARVTLSDGR-TREADAVVGADGVNSMVARALNG-PLPSRYVGYTAWRG
MMAR_4944|M.marinum_M --ATATFADGT-IASADILIGADGANSITREYVLGGPVTRRYAGYVNYNG
MAV_4429|M.avium_104 --VSVEFTDGT-VAEGDVLIGADGLHSMVREWVGA--RHAKATGWCSWQG
TH_0968|M.thermoresistible__bu DGVTVEFADGHPPVRASYVVGCDGGRSTTRRLMGV-----SFDGTTSSTR
MLBr_02276|M.leprae_Br4923 RAASVTLADGT-EVGCRQLIIADGARSPLGRKLGR-SWHQKTVYGVAARG
. : .** *
Mb0590c|M.bovis_AF2122/97 ACVVDGYRPRDERSYVLYNT-----VDRQLARFALRG---DRTMFLFVFR
Rv1260|M.tuberculosis_H37Rv IFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARA---ALAFMDTELR
MUL_1770|M.ulcerans_Agy99 WFSAPDTVGLNGWYLMYQAPGGLNASMRPSHDPATAK---AGLAFRSAPI
MAB_3330|M.abscessus_ATCC_1997 LIPVERLDGVIDLNSMQMWLG----PGRSFLIYPVSRGRLLNVVAFTPSN
MSMEG_3841|M.smegmatis_MC2_155 AG---RMAAFLDGHTMAIVKGDRGDQGVDLVTYPIAP-DLVNWVVQVPQS
Mflv_2621|M.gilvum_PYR-GCK IAAH-PLDPELGGETLG--------PGTQVGHVPLGP----DHTYWFATE
Mvan_3960|M.vanbaalenii_PYR-1 VAAY-RLDPALAGETMS--------AGTEVGHVPLGP----DHTYWFATE
MMAR_4944|M.marinum_M LVEVDEAISPANEWTMYVGD------GKRVSAMPVAD---DRFYFFFDVV
MAV_4429|M.avium_104 LVSLPEIAESDAALMMIGGSG-------NLGLWPAGG----AEVQWWFDL
TH_0968|M.thermoresistible__bu WLVVDVANDPLG------------HPNSEVGADPARP-----YVSISIAH
MLBr_02276|M.leprae_Br4923 YLTTPRSDDLWLTSHLELRSPDGAVLPGYGWIFPLGN-----GEVNIGVG
Mb0590c|M.bovis_AF2122/97 AEHDNPGVAPKDELRDQFGDVGWESR-----DILAALDDVEDLYFDVVSQ
Rv1260|M.tuberculosis_H37Rv IDYRDT-EAQFAELQRRMAEDGWVRA-----QLLHYMRSAPDFYFDEMSQ
MUL_1770|M.ulcerans_Agy99 RYDRGDLDAQRDLLAACFAGAGWQSD-----ALIAAAREADDFYLDAIVQ
MAB_3330|M.abscessus_ATCC_1997 LDAEESWTAPGDVAELSAEFAGWDQP---VQRVAGAMT--ETFRWGLYDR
MSMEG_3841|M.smegmatis_MC2_155 APTSAGWNTPASAADVLPHVAGWRLDWLDVDSLIGSTP--QIFTYPMVDK
Mflv_2621|M.gilvum_PYR-GCK RTAEGGSAPGGEHAYLTAKVADWADP---IPRLVATTDPGDLLRNDLYDR
Mvan_3960|M.vanbaalenii_PYR-1 RTREGSRSAGGEHAYLTAKLAGWADP---IPALLASTDPADVLRNDLYDR
MMAR_4944|M.marinum_M EPEGLPFEKGTAREVLREQFAGWAPG---VQALIDKLDPTTTNRVEILDL
MAV_4429|M.avium_104 PWSTGFVRPQHPIETIRSHFAGWSEP---VDRVLAILTDEDLAASPFPHF
TH_0968|M.thermoresistible__bu GIRRFEFMIHPHETDAEVDDPAFVRR--MLGRRIPYPERVDMIRYRVYTH
MLBr_02276|M.leprae_Br4923 ALSTSKRPADLALRSLISYYTDLRRH------EWGFSGQPRAVSSALLPM
Mb0590c|M.bovis_AF2122/97 I-RMDRWSR-GRVLLIGDAAGCISLLGGEGTGLAITEAYVLAGELARAGG
Rv1260|M.tuberculosis_H37Rv I-LMDRWSR-GRVALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGD
MUL_1770|M.ulcerans_Agy99 I-HLDAWSR-GRVTLVGDAGYCASPLSGMGTSLALVGAYVLAGELGPAHG
MAB_3330|M.abscessus_ATCC_1997 K-PLNRWTT-DRIALLGDAAHPMTPHLGQGANMSIEDAVVLATVLAGASA
MSMEG_3841|M.smegmatis_MC2_155 D-PVRQWGRGGRVTLLGDAAHPMYPVGANGGSQAVVDARVLADHLAEAG-
Mflv_2621|M.gilvum_PYR-GCK A-RAARWSD-GRAVLIGDAAHPMRPHLGQGGCQGIEDAAILARFLELAD-
Mvan_3960|M.vanbaalenii_PYR-1 A-QPRDWSR-GPAVIVGDAAHPMRPHLGQGGCQGLEDAAILARFVGLSP-
MMAR_4944|M.marinum_M D-PFHTWVK-GRVAVLGDAAHNTTPDIGQGGCSAMEDAVALQWALKDNPT
MAV_4429|M.avium_104 R-HPIPPPGRGRVTLLGDAAHTMPPTLAQGTNQALLDTMVLCQALADFGR
TH_0968|M.thermoresistible__bu HSRIAGSFRKGRLLLAGDAAHLMPVWQGQGYNSGIRDAANLGWKLAAVVN
MLBr_02276|M.leprae_Br4923 GGAVSGVAG-PNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLDLRDL
: ***. . * .: :
Mb0590c|M.bovis_AF2122/97 D-------HRRAFDAYEKRLRPFIEGKQASAAKFIWFFRHP---------
Rv1260|M.tuberculosis_H37Rv D-------YQLGFANYHAEFHGFVERNQ-------WLVSDN---------
MUL_1770|M.ulcerans_Agy99 DGID-EAALAAALARYETVLRPYVANCQDLPNSIDRFLPMSESEIRSN--
MAB_3330|M.abscessus_ATCC_1997 T------EVPRRLSLYESLRRDRTSRVQRNARQSGRVYRSVDLTAQQ---
MSMEG_3841|M.smegmatis_MC2_155 ---------VRGLRTYEAERADETAAVIVAN-------REMHRAANT---
Mflv_2621|M.gilvum_PYR-GCK -------DVPTAFERFEAFRKPRVGMLVREAQTLGRIVNVRPAVLSG---
Mvan_3960|M.vanbaalenii_PYR-1 -------DLPAAFDRFGAFRRRRVRPLVRESAAIGRIVNLRPAFLSG---
MMAR_4944|M.marinum_M D-------VAAALAAYQASRTERAGDLVLRARKRCDVIHAKDPDTTA---
MAV_4429|M.avium_104 GTPGGQADVANALRWYEKTRRRRVRAVSWVASLPVSHGEAVLRPAALVSD
TH_0968|M.thermoresistible__bu G-----HAHDALLDTYDLERREHARAMIDLSTMVGRVISPTNRRVAALRD
MLBr_02276|M.leprae_Br4923 S-----YVWPSLLQQHYGRGFSVARRLALLLTFKRCLPAIGPSAMRS---
: .
Mb0590c|M.bovis_AF2122/97 -------NPIRPVVSQRCDAHDELRPAGDAVRRQRA--------------
Rv1260|M.tuberculosis_H37Rv -------IPGGAPIPQ-----EEFERIVHSITIKDY--------------
MUL_1770|M.ulcerans_Agy99 ----AAAMKYMQRWPFRFFAERKWFTIAESIELPRYPRLP----------
MAB_3330|M.abscessus_ATCC_1997 -----QAAQLTEILADNWIPDYDAAATAGTALATL---------------
MSMEG_3841|M.smegmatis_MC2_155 -----RSATELDRVTRKYRTDTARSTRA----------------------
Mflv_2621|M.gilvum_PYR-GCK -----LAGRATALIPERMVTAHLAWIAAGSAFVLPTAADLAR--------
Mvan_3960|M.vanbaalenii_PYR-1 -----VASRASALIPEWAVASHLASIAAGSAFILPTAGDVGG--------
MMAR_4944|M.marinum_M ----AWYEELRNEDGTNIIRGLVANIMGGPLTPLS---------------
MAV_4429|M.avium_104 RLQAAALTMFLRWTSHRRMSDHINRSVGEAINRSLGEAPKIPSRR-----
TH_0968|M.thermoresistible__bu R---LIHAASVVPTLKRYVLEMRFKPMPRYLQGAVYHGGPRSKSSPTGTL
MLBr_02276|M.leprae_Br4923 ----TSLITIAVRVMANLVTDDDADWVARVWRSGGWASWLVDRRPPFS--
Mb0590c|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1770|M.ulcerans_Agy99 --------------------------------------------------
MAB_3330|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3841|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3960|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4944|M.marinum_M --------------------------------------------------
MAV_4429|M.avium_104 --------------------------------------------------
TH_0968|M.thermoresistible__bu FIQPRVDTRDAENVLLDDVLGPGFAVLCWSNNLRAVLGEDAFSHWKSLGA
MLBr_02276|M.leprae_Br4923 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1770|M.ulcerans_Agy99 --------------------------------------------------
MAB_3330|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3841|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3960|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4944|M.marinum_M --------------------------------------------------
MAV_4429|M.avium_104 --------------------------------------------------
TH_0968|M.thermoresistible__bu TFVEARPITQLHWPGHDDPDVVVVGDRTGALKGWFDVHTDSVLFLRPDRC
MLBr_02276|M.leprae_Br4923 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1770|M.ulcerans_Agy99 --------------------------------------------------
MAB_3330|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3841|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2621|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3960|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4944|M.marinum_M --------------------------------------------------
MAV_4429|M.avium_104 --------------------------------------------------
TH_0968|M.thermoresistible__bu IAAACIAQRAPETSAALSEVMCLTQGGGNGAASPVLHVAQSAAEPSGTAT
MLBr_02276|M.leprae_Br4923 --------------------------------------------------
Mb0590c|M.bovis_AF2122/97 ---
Rv1260|M.tuberculosis_H37Rv ---
MUL_1770|M.ulcerans_Agy99 ---
MAB_3330|M.abscessus_ATCC_1997 ---
MSMEG_3841|M.smegmatis_MC2_155 ---
Mflv_2621|M.gilvum_PYR-GCK ---
Mvan_3960|M.vanbaalenii_PYR-1 ---
MMAR_4944|M.marinum_M ---
MAV_4429|M.avium_104 ---
TH_0968|M.thermoresistible__bu RST
MLBr_02276|M.leprae_Br4923 ---