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MSAHSAQKSLFARMIRKYSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSKALIHIGESFQ ESDSNSLAMVILEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLWGQGTTAAGVQSSDGQAAYTLVRV AGDQGSTVSDESIRAVRELVAEVQPPNGVKVYVSGSAPLSTDMLQVGNQSMIRLMYVTIVIITVMLLIVY RSFTTAFLTLLIVMVELSCGRGVVAFLAYHKLIGISVFASNILVSLILGAGTDYAIFLIGRYQEARHAGE DRETAYYSAVKGVSHVILGSGLAIAGATFCLQFTRLNYFNTMGLPCAAATLVAVAASLTFGPAVLALGSR FGIFDPKRKADSGIWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPNYNDRIYIAGDVPANQGYAAA DRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPGVAMIQSVTRPLGTPLEHSSFTYTMGTM GTKINEILPFLTDLTDRFTQMADITDRMAALMRQQQGLTGQQAGASHISLKGAQELKDVTVTMRDTLANF DDQFRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMTDAVDDSLKAAVIQDAVTPQLVEVIGKSAAE LDNMRKVVLTEQSTMRPMLTQMNELGRQMMDLGYAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGK SARYMIYHDGEALSTEGIDHAQAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLLIAAIAAF ALIFLVMLVITRSVVAALVIVGTVAFSYSGAFGLSVLVWQHFLGIPLSWLNLPITFIILVAVGSDYNLLL ISRYLEESKAGLNTGLIRAVANSGKVVTTAGIVFATTMMAMLSSDLLSVGQLGSIIGLGLLLDTLIVRSF ITPAIARLLGPLFWWPRLIRSRPAPAQYR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2650 | - | - | 100% (939) | MmpL family protein |
| M. abscessus ATCC 19977 | MAB_4768c | - | 0.0 | 51.29% (932) | putative membrane protein, MmpL |
| M. abscessus ATCC 19977 | MAB_2037 | - | 0.0 | 49.95% (935) | putative membrane protein MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 49.57% (928) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 48.57% (943) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 49.68% (928) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 47.78% (923) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_3048 | mmpL5_5 | 0.0 | 50.75% (928) | transmembrane transport protein, MmpL5_5 |
| M. avium 104 | MAV_3863 | - | 0.0 | 49.09% (939) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0185 | - | 0.0 | 49.62% (933) | MmpL6 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 46.42% (937) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 49.52% (933) | transmembrane transport protein MmpL4_1 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 47.61% (943) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 ------MSTKFANDSNTNARPEK------------------PFIARMIHA
Rv0450c|M.tuberculosis_H37Rv ------MSTKFANDSNTNARPEK------------------PFIARMIHA
MLBr_02378|M.leprae_Br4923 ------MTVKCANDLDTHTKP--------------------PFVARMIHR
Mflv_3435|M.gilvum_PYR-GCK ------MSAPVS-DARTDEFPAAHGPHRS-------------FIPRMIRL
Mvan_3189|M.vanbaalenii_PYR-1 ------MSAPVS-DARTDEFPAARQPHRP-------------FIPRMIRL
TH_3260|M.thermoresistible__bu ------MTANPG-HVRTDEAPTDRLDIKVS-------THGPSFISTWIRR
MUL_3688|M.ulcerans_Agy99 ------MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRI
MAV_3863|M.avium_104 ------MTTDQATRS---------------------------VVAQTIRR
MMAR_3048|M.marinum_M ------MSGKSGNDR--------------------------PRFMRMVRA
MAB_2650|M.abscessus_ATCC_1997 ------MSAHSAQKS---------------------------LFARMIRK
MSMEG_0185|M.smegmatis_MC2_155 MPGQVRMSAHRAGRP---------------------------FFARTVRV
*: . . ::
Mb0458c|M.bovis_AF2122/97 FAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGM
Rv0450c|M.tuberculosis_H37Rv FAVPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGM
MLBr_02378|M.leprae_Br4923 FAVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQ
Mflv_3435|M.gilvum_PYR-GCK FAVPIILGWIALIVVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGE
Mvan_3189|M.vanbaalenii_PYR-1 FAVPIILGWIALIVILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGE
TH_3260|M.thermoresistible__bu LSLPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGE
MUL_3688|M.ulcerans_Agy99 LAVPIILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGH
MAV_3863|M.avium_104 LSVPILLVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAMQHIGK
MMAR_3048|M.marinum_M FAIPIILIWLLLTIAVNVFVPQIEFVARDNAVTMSPQDAPAMIAAKRIGK
MAB_2650|M.abscessus_ATCC_1997 YSILVVLAWVAFTVVINVVVPQLEPVTDANQGPLVPLDAPSSKALIHIGE
MSMEG_0185|M.smegmatis_MC2_155 LAVPIIVFWGLLAVTTNTFIPQVEHVADELAGPMIPNYAPSQVALLHIGE
:: ::: * . . :*.:* * .: . **: : ::*
Mb0458c|M.bovis_AF2122/97 VFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLW
Rv0450c|M.tuberculosis_H37Rv VFKEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLW
MLBr_02378|M.leprae_Br4923 VFNEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFW
Mflv_3435|M.gilvum_PYR-GCK LFEEGDSDSSVMIVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFW
Mvan_3189|M.vanbaalenii_PYR-1 LFREGDSDSSVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFW
TH_3260|M.thermoresistible__bu LFDEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLW
MUL_3688|M.ulcerans_Agy99 NFREFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFW
MAV_3863|M.avium_104 VFHEYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEHVQNFW
MMAR_3048|M.marinum_M TFHESDSDSIVMIVLESDKELGDAAHRYYDGLVQKLEADTEHVQHVHNLW
MAB_2650|M.abscessus_ATCC_1997 SFQESDSNSLAMVILEGDHKLNDADHKFYDVLASKLENDKKHVQYVMNLW
MSMEG_0185|M.smegmatis_MC2_155 KFQESDSTNLTMLVFEADRPLDDGDHRYYDDLVRRLQADTEHVQYVMDLW
* * .* . *:::*.:. *. : :** * :*. * *:: : ::*
Mb0458c|M.bovis_AF2122/97 GDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---
Rv0450c|M.tuberculosis_H37Rv GDPLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---
MLBr_02378|M.leprae_Br4923 GDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---
Mflv_3435|M.gilvum_PYR-GCK SDPLTASGSQSNDGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---
Mvan_3189|M.vanbaalenii_PYR-1 SDPLTASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---
TH_3260|M.thermoresistible__bu SDPLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEM
MUL_3688|M.ulcerans_Agy99 GDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTH---
MAV_3863|M.avium_104 GDPLTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIVEHTP---
MMAR_3048|M.marinum_M ADRITAAGVQSGDGKAAYVQLNIAGNQGSTLGNESVDAVRAIVDRSP---
MAB_2650|M.abscessus_ATCC_1997 GQGTTAAGVQSSDGQAAYTLVRVAGDQGSTVSDESIRAVRELVAEVQ---
MSMEG_0185|M.smegmatis_MC2_155 GKPITAAGAQSVDGKASFVLLRLAGNIGQLEANESVDAVRDIIADDA---
.. **.* ** **::::. : ::*: * .:**: : : :
Mb0458c|M.bovis_AF2122/97 APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSII
Rv0450c|M.tuberculosis_H37Rv APPGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSII
MLBr_02378|M.leprae_Br4923 APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFI
Mflv_3435|M.gilvum_PYR-GCK PPPGVRAFVTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIV
Mvan_3189|M.vanbaalenii_PYR-1 PPPGVRAFVTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIV
TH_3260|M.thermoresistible__bu APEGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVI
MUL_3688|M.ulcerans_Agy99 EPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIV
MAV_3863|M.avium_104 PPPGVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVYRS-V
MMAR_3048|M.marinum_M PPDGMRVYITGPAALTTDMNEAADKSMFKMMGVTGVVIMIMLFIVYRSVS
MAB_2650|M.abscessus_ATCC_1997 PPNGVKVYVSGSAPLSTDMLQVGNQSMIRLMYVTIVIITVMLLIVYRSFT
MSMEG_0185|M.smegmatis_MC2_155 PPQGLKVYVSGAAPLASDTLSTANSSLNNITIFTIILIVVMLLLVYRSAA
* *: .:::* :.: * .. .: : : * *: ****
Mb0458c|M.bovis_AF2122/97 TVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDY
Rv0450c|M.tuberculosis_H37Rv TVVLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDY
MLBr_02378|M.leprae_Br4923 TVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDY
Mflv_3435|M.gilvum_PYR-GCK TVLITLVMVVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDY
Mvan_3189|M.vanbaalenii_PYR-1 TVLLTLVMVVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDY
TH_3260|M.thermoresistible__bu TVLIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDY
MUL_3688|M.ulcerans_Agy99 TTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDY
MAV_3863|M.avium_104 TAVFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAAGTDY
MMAR_3048|M.marinum_M TVLLVLAMVGFEMGTARGVIALLGHHHLLGFSTFVVAMLSSLAIAAGTDY
MAB_2650|M.abscessus_ATCC_1997 TAFLTLLIVMVELSCGRGVVAFLAYHKLIGISVFASNILVSLILGAGTDY
MSMEG_0185|M.smegmatis_MC2_155 CLLVPLPAVLIEMLVAKGVIATLGHFGLIPLSSFAVNVVVALTLGAGTDY
.. * . . :*::* *. : :: :. :: * :. ..**
Mb0458c|M.bovis_AF2122/97 GIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFA
Rv0450c|M.tuberculosis_H37Rv GIFIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFA
MLBr_02378|M.leprae_Br4923 GIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFA
Mflv_3435|M.gilvum_PYR-GCK AIFLIGRYQEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFT
Mvan_3189|M.vanbaalenii_PYR-1 AIFLIGRYQEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFT
TH_3260|M.thermoresistible__bu AIFLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFT
MUL_3688|M.ulcerans_Agy99 GIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFA
MAV_3863|M.avium_104 AIFFVGRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLCLRFT
MMAR_3048|M.marinum_M AIFLIGRYQEARQAGEDRETAYYSMFRGTYHVILGSGLTIAGATFCLHLA
MAB_2650|M.abscessus_ATCC_1997 AIFLIGRYQEARHAGEDRETAYYSAVKGVSHVILGSGLAIAGATFCLQFT
MSMEG_0185|M.smegmatis_MC2_155 GIFLLGRYHEARQSGESREDAYFTAYRSVAPIIIGSGLTIAGACFCLSLA
.**: ***:*** . .: *:.: .. :::.***:::** ** ::
Mb0458c|M.bovis_AF2122/97 RMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVR
Rv0450c|M.tuberculosis_H37Rv RMPYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVR
MLBr_02378|M.leprae_Br4923 RMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVR
Mflv_3435|M.gilvum_PYR-GCK RLPYFQTMGVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIR
Mvan_3189|M.vanbaalenii_PYR-1 RLPYFQTLGVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIR
TH_3260|M.thermoresistible__bu RLPYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVR
MUL_3688|M.ulcerans_Agy99 RLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGR
MAV_3863|M.avium_104 RLNYFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKRQMATR
MMAR_3048|M.marinum_M RLSYFKALGIPSALGLLVVIAGALTAAPAIVAVATRFG-LLDPRRMIKVR
MAB_2650|M.abscessus_ATCC_1997 RLNYFNTMGLPCAAATLVAVAASLTFGPAVLALGSRFG-IFDPKRKADSG
MSMEG_0185|M.smegmatis_MC2_155 RLDYFHTMGPAVAISMLFTIAAALTLAPALLTLGSLLA-LFDPKRPTRGH
*: :*:::* . * . . : .: * : :.: : : . :
Mb0458c|M.bovis_AF2122/97 GWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPA
Rv0450c|M.tuberculosis_H37Rv GWRRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPA
MLBr_02378|M.leprae_Br4923 GWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPA
Mflv_3435|M.gilvum_PYR-GCK GWRKIGAAIVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPA
Mvan_3189|M.vanbaalenii_PYR-1 GWRKIGAAVVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPA
TH_3260|M.thermoresistible__bu FWRKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPS
MUL_3688|M.ulcerans_Agy99 LWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPS
MAV_3863|M.avium_104 GWRRIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPASAPA
MMAR_3048|M.marinum_M GWRRIGTATVRWPGPVFVASLLIALVGMMVVPGMKISYNDRYYIPRNLPS
MAB_2650|M.abscessus_ATCC_1997 IWRKVGTVTVRWPGRILVVSSVVVMIGSITLPTYKPNYNDRIYIAGDVPA
MSMEG_0185|M.smegmatis_MC2_155 LYRRIGTSVVRWPKPIFVASAAVVMVGAVFVPSYRVNYDDRAYQPVDAAA
:*::*: **** :: : :.::* : :* : .*. * * . .:
Mb0458c|M.bovis_AF2122/97 NQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPG
Rv0450c|M.tuberculosis_H37Rv NQGYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPG
MLBr_02378|M.leprae_Br4923 NQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPG
Mflv_3435|M.gilvum_PYR-GCK NQGYAVADEHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEG
Mvan_3189|M.vanbaalenii_PYR-1 NEGYAVADRHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEG
TH_3260|M.thermoresistible__bu NAGYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEG
MUL_3688|M.ulcerans_Agy99 NLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVG
MAV_3863|M.avium_104 NTGYTAAERHFSQARLNPELLMIETDHDMRNPADMINLERVAKAIAHLPG
MMAR_3048|M.marinum_M NVGYVAAEQHFSAARLNPDILMIEGDHDMRNSSDMILLDRIAKEVFRAPG
MAB_2650|M.abscessus_ATCC_1997 NQGYAAADRHFPVSKLNSDMLMVESDHDMRNSTDMIALDKVAREVFHTPG
MSMEG_0185|M.smegmatis_MC2_155 NLGFQAADRHFNQSKLFSEMLMIETDHDMRNSADFISLDRVAKALIRLPG
* * .*:.** ::: .::*::* :**:**.:*:: ::::*: : : *
Mb0458c|M.bovis_AF2122/97 ISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQAD
Rv0450c|M.tuberculosis_H37Rv ISRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQAD
MLBr_02378|M.leprae_Br4923 ISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAE
Mflv_3435|M.gilvum_PYR-GCK IARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQAD
Mvan_3189|M.vanbaalenii_PYR-1 IARVQAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQAD
TH_3260|M.thermoresistible__bu ISRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQAD
MUL_3688|M.ulcerans_Agy99 IAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMAD
MAV_3863|M.avium_104 IAQVQSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDLLKQAD
MMAR_3048|M.marinum_M IARVQSITRPLGSPIEHSSIPFQVSMQALPIQQNLKFMKERTADMLKMSD
MAB_2650|M.abscessus_ATCC_1997 VAMIQSVTRPLGTPLEHSSFTYTMGTMGTKINEILPFLTDLTDRFTQMAD
MSMEG_0185|M.smegmatis_MC2_155 VAMVQSITRPLGRPLEHATIPYLFTTQGSTNGQQLPFSEQANENTDRQAE
:: :* :*** * .:.*:::.: : : ::
Mb0458c|M.bovis_AF2122/97 EMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDF
Rv0450c|M.tuberculosis_H37Rv EMATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDF
MLBr_02378|M.leprae_Br4923 NMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDF
Mflv_3435|M.gilvum_PYR-GCK EMANTIKTMEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDF
Mvan_3189|M.vanbaalenii_PYR-1 EMANTIATMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDF
TH_3260|M.thermoresistible__bu EMQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDF
MUL_3688|M.ulcerans_Agy99 EMQVLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDF
MAV_3863|M.avium_104 NLKDTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIANFDDF
MMAR_3048|M.marinum_M DLGAMIASMERMQGLLGQMSGTTHRMVGDMGEMRVTLNEMRDHLADFDDF
MAB_2650|M.abscessus_ATCC_1997 ITDRMAALMRQQQGLTGQQAGASHISLKGAQELKDVTVTMRDTLANFDDQ
MSMEG_0185|M.smegmatis_MC2_155 IQARSVEVLQHVITITQQMSAELHSTVLTFENLKEVTDEVNEGISNLDDF
: : :.: ::::**
Mb0458c|M.bovis_AF2122/97 WRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREM
Rv0450c|M.tuberculosis_H37Rv WRPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREM
MLBr_02378|M.leprae_Br4923 WRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNM
Mflv_3435|M.gilvum_PYR-GCK FRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRL
Mvan_3189|M.vanbaalenii_PYR-1 FRPIRNYFYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRL
TH_3260|M.thermoresistible__bu FRPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRL
MUL_3688|M.ulcerans_Agy99 WRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRT
MAV_3863|M.avium_104 FRPVRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTASLDKL
MMAR_3048|M.marinum_M ARPFRGYLYWEQHCFNIPVCWASRSVFDAIDGVDKFSENMDALIGDMNDV
MAB_2650|M.abscessus_ATCC_1997 FRPLRNYFYWEPHCADIPMCWAMRSLFDMTDQVDSMTDAVDDSLKAAVIQ
MSMEG_0185|M.smegmatis_MC2_155 LRPLKNYFYWEPHCFDIPVCFAMRSLFDSLDGIDSLDEQIGNAVVSFEAI
**.:.*:*** ** .:* *:: **:** * :: : .
Mb0458c|M.bovis_AF2122/97 DRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMG
Rv0450c|M.tuberculosis_H37Rv DRLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMG
MLBr_02378|M.leprae_Br4923 DLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMG
Mflv_3435|M.gilvum_PYR-GCK DTLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMG
Mvan_3189|M.vanbaalenii_PYR-1 DSLMPQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMG
TH_3260|M.thermoresistible__bu NDLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMG
MUL_3688|M.ulcerans_Agy99 AGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMG
MAV_3863|M.avium_104 DAGQQKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDTATALG
MMAR_3048|M.marinum_M DSILPRMQAEFPSMIAVATSMRGTLLTLHSSFSGLVTQMSRMTDTASAMG
MAB_2650|M.abscessus_ATCC_1997 DAVTPQLVEVIGKSAAELDNMRKVVLTEQSTMRPMLTQMNELGRQMMDLG
MSMEG_0185|M.smegmatis_MC2_155 DRLLPQMITQLERMIADSRALLGVITNNYGPAHLQSTQTDQTYYDQINVG
:: : . . * :*
Mb0458c|M.bovis_AF2122/97 KAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQ
Rv0450c|M.tuberculosis_H37Rv KAFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQ
MLBr_02378|M.leprae_Br4923 KAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPA
Mflv_3435|M.gilvum_PYR-GCK EAFDDSMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPL
Mvan_3189|M.vanbaalenii_PYR-1 EAFDDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPL
TH_3260|M.thermoresistible__bu EAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPM
MUL_3688|M.ulcerans_Agy99 QSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPM
MAV_3863|M.avium_104 QAYDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISHEGDPA
MMAR_3048|M.marinum_M QAFDASKADDYFYLPPEAFDNPDFQRGLKLFLSSDGKAARFIITHDSDPA
MAB_2650|M.abscessus_ATCC_1997 YAFDSSKNDEFFYLPPDAFDNPYFQIDLKYFVSPDGKSARYMIYHDGEAL
MSMEG_0185|M.smegmatis_MC2_155 NDFDAARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAM
:* : *: **:* : * * .: :. ::*.**::.* :* * .:.
Mb0458c|M.bovis_AF2122/97 SPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLL
Rv0450c|M.tuberculosis_H37Rv SPEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLL
MLBr_02378|M.leprae_Br4923 SVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLV
Mflv_3435|M.gilvum_PYR-GCK SPEGVAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLL
Mvan_3189|M.vanbaalenii_PYR-1 SPEGVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLL
TH_3260|M.thermoresistible__bu TPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLI
MUL_3688|M.ulcerans_Agy99 TPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLM
MAV_3863|M.avium_104 TPEGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLL
MMAR_3048|M.marinum_M TPKGIAAVKPELNAARQAVKGTPLADAKFYLTGTAAIYNDIQTGSKYDIL
MAB_2650|M.abscessus_ATCC_1997 STEGIDHAQAYLPKAKEALKGTTLAGSRVYLGGAAATYWDIQDATKTDLL
MSMEG_0185|M.smegmatis_MC2_155 APEGIEHVEQFPDAIKMALKETSLAGAKIYIGGAASNNLDIKTYAASDLL
: *: . .:* :.* .:..*: *:*: *: *::
Mb0458c|M.bovis_AF2122/97 IAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHIL
Rv0450c|M.tuberculosis_H37Rv IAAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHIL
MLBr_02378|M.leprae_Br4923 IAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHIL
Mflv_3435|M.gilvum_PYR-GCK IAGIAALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHIL
Mvan_3189|M.vanbaalenii_PYR-1 IAGISALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHIL
TH_3260|M.thermoresistible__bu IAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIV
MUL_3688|M.ulcerans_Agy99 IAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLF
MAV_3863|M.avium_104 IAGIAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDIL
MMAR_3048|M.marinum_M IVGIAALTLIFVVMVIITRALVASLVIVGTVLLSLGAAFGLSVLVWQHIL
MAB_2650|M.abscessus_ATCC_1997 IAAIAAFALIFLVMLVITRSVVAALVIVGTVAFSYSGAFGLSVLVWQHFL
MSMEG_0185|M.smegmatis_MC2_155 IVAIAAFVLIFLIMLYLTRSLVAALVIPGTVAFSFAGAFGLSVMMWQHLI
*. :::. **:::*: :**:.:*: ** **. * ..:**:**:.** :.
Mb0458c|M.bovis_AF2122/97 AIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGT
Rv0450c|M.tuberculosis_H37Rv AIHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGT
MLBr_02378|M.leprae_Br4923 GIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGT
Mflv_3435|M.gilvum_PYR-GCK GQPLHWMVLAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGS
Mvan_3189|M.vanbaalenii_PYR-1 GTELHWMVLAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGS
TH_3260|M.thermoresistible__bu GLEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGS
MUL_3688|M.ulcerans_Agy99 GIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGT
MAV_3863|M.avium_104 GIKLYWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGS
MMAR_3048|M.marinum_M GLDLNWIAPVFGVIILLAVGSDYNLLLVSRFQEEIGAGLKTGIIRSMGET
MAB_2650|M.abscessus_ATCC_1997 GIPLSWLNLPITFIILVAVGSDYNLLLISRYLEESKAGLNTGLIRAVANS
MSMEG_0185|M.smegmatis_MC2_155 GLPLHWLILPLSFIILVAVGSDYNLLLISRVKEETGAGLNTGLIRALGST
. : :: : .*:*:***:*****:::* :* **: **:**::. :
Mb0458c|M.bovis_AF2122/97 GKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
Rv0450c|M.tuberculosis_H37Rv GKVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
MLBr_02378|M.leprae_Br4923 GKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMP
Mflv_3435|M.gilvum_PYR-GCK GSVVTAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTP
Mvan_3189|M.vanbaalenii_PYR-1 GSVVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTP
TH_3260|M.thermoresistible__bu GSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMP
MUL_3688|M.ulcerans_Agy99 GGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMP
MAV_3863|M.avium_104 GAVVTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVRSFMTP
MMAR_3048|M.marinum_M GGVVTAAGLVFAFTMLSMVASDLRSIGQAGSTIGLGLLFDTLIVRSLMTP
MAB_2650|M.abscessus_ATCC_1997 GKVVTTAGIVFATTMMAMLSSDLLSVGQLGSIIGLGLLLDTLIVRSFITP
MSMEG_0185|M.smegmatis_MC2_155 GAVVTSAGLVFAFTMLSMLVSDLRTIGQLGTTVCIGLLLDTMIVRSLVVP
* *** **:**. ** : :.* :** *: : :***:**:::*::: *
Mb0458c|M.bovis_AF2122/97 SIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----
Rv0450c|M.tuberculosis_H37Rv SIAALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-----
MLBr_02378|M.leprae_Br4923 SIAALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD---------
Mflv_3435|M.gilvum_PYR-GCK SIAALLGPWFWWPQRVRTRPVPAPWPRSGGLQSDPSEGVRA---------
Mvan_3189|M.vanbaalenii_PYR-1 SIAALLGPWFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV---------
TH_3260|M.thermoresistible__bu SIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---------
MUL_3688|M.ulcerans_Agy99 SIATLLGRWFWWPQVVHPR-GDNARPRVAAPTH-----------------
MAV_3863|M.avium_104 SVAALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDPAVAPE
MMAR_3048|M.marinum_M SVAALLGRWFWWPLRVRPRPASYMLRPFGPRRLVRSLLLGEPTDVATSQP
MAB_2650|M.abscessus_ATCC_1997 AIARLLGPLFWWPRLIRSRPAPAQYR------------------------
MSMEG_0185|M.smegmatis_MC2_155 CLLRLLGPWFWWPTFIRQRPLRQAVRQRERADVV----------------
.: *** **** : *
Mb0458c|M.bovis_AF2122/97 ----------------------------------
Rv0450c|M.tuberculosis_H37Rv ----------------------------------
MLBr_02378|M.leprae_Br4923 ----------------------------------
Mflv_3435|M.gilvum_PYR-GCK ----------------------------------
Mvan_3189|M.vanbaalenii_PYR-1 ----------------------------------
TH_3260|M.thermoresistible__bu ----------------------------------
MUL_3688|M.ulcerans_Agy99 ----------------------------------
MAV_3863|M.avium_104 TPSAARHSRG------------------------
MMAR_3048|M.marinum_M AGYGGSPERSNGDPATVPAAVPAPETGGADGSAR
MAB_2650|M.abscessus_ATCC_1997 ----------------------------------
MSMEG_0185|M.smegmatis_MC2_155 ----------------------------------