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SGKSGNDRPRFMRMVRAFAIPIILIWLLLTIAVNVFVPQIEFVARDNAVTMSPQDAPAMIAAKRIGKTFH ESDSDSIVMIVLESDKELGDAAHRYYDGLVQKLEADTEHVQHVHNLWADRITAAGVQSGDGKAAYVQLNI AGNQGSTLGNESVDAVRAIVDRSPPPDGMRVYITGPAALTTDMNEAADKSMFKMMGVTGVVIMIMLFIVY RSVSTVLLVLAMVGFEMGTARGVIALLGHHHLLGFSTFVVAMLSSLAIAAGTDYAIFLIGRYQEARQAGE DRETAYYSMFRGTYHVILGSGLTIAGATFCLHLARLSYFKALGIPSALGLLVVIAGALTAAPAIVAVATR FGLLDPRRMIKVRGWRRIGTATVRWPGPVFVASLLIALVGMMVVPGMKISYNDRYYIPRNLPSNVGYVAA EQHFSAARLNPDILMIEGDHDMRNSSDMILLDRIAKEVFRAPGIARVQSITRPLGSPIEHSSIPFQVSMQ ALPIQQNLKFMKERTADMLKMSDDLGAMIASMERMQGLLGQMSGTTHRMVGDMGEMRVTLNEMRDHLADF DDFARPFRGYLYWEQHCFNIPVCWASRSVFDAIDGVDKFSENMDALIGDMNDVDSILPRMQAEFPSMIAV ATSMRGTLLTLHSSFSGLVTQMSRMTDTASAMGQAFDASKADDYFYLPPEAFDNPDFQRGLKLFLSSDGK AARFIITHDSDPATPKGIAAVKPELNAARQAVKGTPLADAKFYLTGTAAIYNDIQTGSKYDILIVGIAAL TLIFVVMVIITRALVASLVIVGTVLLSLGAAFGLSVLVWQHILGLDLNWIAPVFGVIILLAVGSDYNLLL VSRFQEEIGAGLKTGIIRSMGETGGVVTAAGLVFAFTMLSMVASDLRSIGQAGSTIGLGLLFDTLIVRSL MTPSVAALLGRWFWWPLRVRPRPASYMLRPFGPRRLVRSLLLGEPTDVATSQPAGYGGSPERSNGDPATV PAAVPAPETGGADGSAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3048 | mmpL5_5 | - | 100% (998) | transmembrane transport protein, MmpL5_5 |
| M. marinum M | MMAR_0775 | - | 0.0 | 57.56% (959) | MmpL family transport protein |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 59.44% (932) | transmembrane transport protein MmpL5_2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 60.67% (928) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 58.17% (930) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 60.78% (928) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 57.07% (934) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_4746 | - | 0.0 | 75.47% (962) | putative membrane protein, MmpL |
| M. avium 104 | MAV_2510 | - | 0.0 | 56.74% (927) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0382 | - | 0.0 | 55.76% (990) | putative transport protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 54.66% (922) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 56.79% (928) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 57.17% (927) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAAHGPHRS------FIPRMIRLFAVPIILGWIALIV
Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRP------FIPRMIRLFAVPIILGWIALIV
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRP------FIPRMIRTFAVPLILGWVLLIA
MAV_2510|M.avium_104 MSTTFDDTRTDAIPVVKEPVREK------IPRFIRAFAVPIIIGWIALIA
Mb0458c|M.bovis_AF2122/97 MSTKFANDSNTNARPEK----------PFIARMIHAFAVPIILGWLAVCV
Rv0450c|M.tuberculosis_H37Rv MSTKFANDSNTNARPEK----------PFIARMIHAFAVPIILGWLAVCV
MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKP------------PFVARMIHRFAVPIILVWLAIAV
MSMEG_0382|M.smegmatis_MC2_155 ----MSTEQSGTEKARR----------PFFARAVRTLSPFIIVGWLAVIL
MMAR_3048|M.marinum_M MSGKS-----GNDRPR-------------FMRMVRAFAIPIILIWLLLTI
MAB_4746|M.abscessus_ATCC_1997 MSGESRVSAPAPERPA-------------FMRFVRRFAVPILTTWLFMTV
. :: :: :: *: :
Mflv_3435|M.gilvum_PYR-GCK VVN---------VTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEG
Mvan_3189|M.vanbaalenii_PYR-1 ILN---------VTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREG
TH_3260|M.thermoresistible__bu LLN---------ITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEG
MUL_0757|M.ulcerans_Agy99 VLN---------SVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREG
MAV_2510|M.avium_104 VLN---------VVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEY
Mb0458c|M.bovis_AF2122/97 VVT---------VFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEG
Rv0450c|M.tuberculosis_H37Rv VVT---------VFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEG
MLBr_02378|M.leprae_Br4923 TVS---------VFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEG
MSMEG_0382|M.smegmatis_MC2_155 VTTLAAVGGDWSAAIPALERVGEKNSVSLMPQDAPSAKAMKHMGQKFEES
MMAR_3048|M.marinum_M AVN---------VFVPQIEFVARDNAVTMSPQDAPAMIAAKRIGKTFHES
MAB_4746|M.abscessus_ATCC_1997 AVN---------VLVPPIESVAREHAVTMSPHDAPAMIAAKHIGQKYHES
. :* :: *.. .:* : *. * : : ::* : *
Mflv_3435|M.gilvum_PYR-GCK DSDSSVMIVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLT
Mvan_3189|M.vanbaalenii_PYR-1 DSDSSVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLT
TH_3260|M.thermoresistible__bu SSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLT
MUL_0757|M.ulcerans_Agy99 DSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLT
MAV_2510|M.avium_104 KSNSSVMIVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLT
Mb0458c|M.bovis_AF2122/97 DSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLT
Rv0450c|M.tuberculosis_H37Rv DSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLT
MLBr_02378|M.leprae_Br4923 NSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLT
MSMEG_0382|M.smegmatis_MC2_155 DSDSFAMIVLEGQEPLGPDALDYYTGLISELRNDSKHVEHVQDLWGDRLT
MMAR_3048|M.marinum_M DSDSIVMIVLESDKELGDAAHRYYDGLVQKLEADTEHVQHVHNLWADRIT
MAB_4746|M.abscessus_ATCC_1997 DSDSIAMIVLESDDPLGERAHQYYDNLVLALQADTRHVQHVQNVWGDPLT
.*:* *:::*.:. ** * :* :: *. * **: *::.*.* :*
Mflv_3435|M.gilvum_PYR-GCK ASGSQSNDGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPGV
Mvan_3189|M.vanbaalenii_PYR-1 ASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPGV
TH_3260|M.thermoresistible__bu ATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGV
MUL_0757|M.ulcerans_Agy99 ATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGV
MAV_2510|M.avium_104 GAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSVQ---APNGV
Mb0458c|M.bovis_AF2122/97 AAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---APPGI
Rv0450c|M.tuberculosis_H37Rv AAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---APPGI
MLBr_02378|M.leprae_Br4923 APGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGI
MSMEG_0382|M.smegmatis_MC2_155 ASSAQSADGKAAYVQLNLAGNQGTPLGDESVAAVRDLVARTP---APEGV
MMAR_3048|M.marinum_M AAGVQSGDGKAAYVQLNIAGNQGSTLGNESVDAVRAIVDRSP---PPDGM
MAB_4746|M.abscessus_ATCC_1997 ASGVQSRDGRAAYVQVNLAGDQGSTLGNKSVVAVREIVDNST---PPQGV
... ** **:::***: ::*:** *.::*: :.: : .* *:
Mflv_3435|M.gilvum_PYR-GCK RAFVTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLIT
Mvan_3189|M.vanbaalenii_PYR-1 RAFVTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLT
TH_3260|M.thermoresistible__bu QAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIA
MUL_0757|M.ulcerans_Agy99 KVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIM
MAV_2510|M.avium_104 KAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLT
Mb0458c|M.bovis_AF2122/97 KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
Rv0450c|M.tuberculosis_H37Rv KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
MLBr_02378|M.leprae_Br4923 TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL
MSMEG_0382|M.smegmatis_MC2_155 SVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILL
MMAR_3048|M.marinum_M RVYITGPAALTTDMNEAADKSMFKMMGVTGVVIMIMLFIVYRSVSTVLLV
MAB_4746|M.abscessus_ATCC_1997 TVYVTGPAALTTDMNEAADKSMLIMMGVTGAVIMIMLLITYRSVSTMLLV
.::** :.: :* : :.: *: : : :* *::.***. * :
Mflv_3435|M.gilvum_PYR-GCK LVMVVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLI
Mvan_3189|M.vanbaalenii_PYR-1 LVMVVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLI
TH_3260|M.thermoresistible__bu LFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLI
MUL_0757|M.ulcerans_Agy99 LTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLI
MAV_2510|M.avium_104 LVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLI
Mb0458c|M.bovis_AF2122/97 LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
Rv0450c|M.tuberculosis_H37Rv LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
MLBr_02378|M.leprae_Br4923 LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT
MSMEG_0382|M.smegmatis_MC2_155 LIMVGFEVAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAAGTDYGIFFF
MMAR_3048|M.marinum_M LAMVGFEMGTARGVIALLGHHHLLGFSTFVVAMLSSLAIAAGTDYAIFLI
MAB_4746|M.abscessus_ATCC_1997 LVMVGFEMGTARGIVAILGNYDLLGFSTFVVAMLSSLAIAAGTDYAIFLI
* * . .:** :*.** : :: *.. :* **** ..**.**:
Mflv_3435|M.gilvum_PYR-GCK GRYQEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYF
Mvan_3189|M.vanbaalenii_PYR-1 GRYQEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYF
TH_3260|M.thermoresistible__bu GRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYF
MUL_0757|M.ulcerans_Agy99 GRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYF
MAV_2510|M.avium_104 GRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYF
Mb0458c|M.bovis_AF2122/97 GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYF
Rv0450c|M.tuberculosis_H37Rv GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYF
MLBr_02378|M.leprae_Br4923 GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF
MSMEG_0382|M.smegmatis_MC2_155 GRYQEARAAGEDRETAYYSMYRGVTPVVMASGLTIAGAIFCLTFTRLPYF
MMAR_3048|M.marinum_M GRYQEARQAGEDRETAYYSMFRGTYHVILGSGLTIAGATFCLHLARLSYF
MAB_4746|M.abscessus_ATCC_1997 GRYQEARQVGQDRENAYYTMFRGTFHIILGSGLTIAGATLCLHLARLSYF
******* . .: *:::*: *. :: .**:**:** ** ::.:.**
Mflv_3435|M.gilvum_PYR-GCK QTMGVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKI
Mvan_3189|M.vanbaalenii_PYR-1 QTLGVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKI
TH_3260|M.thermoresistible__bu QSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKV
MUL_0757|M.ulcerans_Agy99 QTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKI
MAV_2510|M.avium_104 QTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKV
Mb0458c|M.bovis_AF2122/97 QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
Rv0450c|M.tuberculosis_H37Rv QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
MLBr_02378|M.leprae_Br4923 QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRI
MSMEG_0382|M.smegmatis_MC2_155 HTMGVPCAIGMLAAVAVAVTLVPAGVALAGRIG-WLEPKRKMRVRRWRGI
MMAR_3048|M.marinum_M KALGIPSALGLLVVIAGALTAAPAIVAVATRFG-LLDPRRMIKVRGWRRI
MAB_4746|M.abscessus_ATCC_1997 KALGIPSALGLLVVVVGALTAAPAVVVVAGRFG-LLDPKRPVNVRRWRRI
:::* * *:*:. : .: * : : *: ::*:* .:* ** :
Mflv_3435|M.gilvum_PYR-GCK GAAIVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYA
Mvan_3189|M.vanbaalenii_PYR-1 GAAVVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYA
TH_3260|M.thermoresistible__bu GASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYE
MUL_0757|M.ulcerans_Agy99 GAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYS
MAV_2510|M.avium_104 GTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYA
Mb0458c|M.bovis_AF2122/97 GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
Rv0450c|M.tuberculosis_H37Rv GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
MLBr_02378|M.leprae_Br4923 GTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFA
MSMEG_0382|M.smegmatis_MC2_155 GTAIVRWPAPILVASLAVALVGLLALPGYETSYNDRDYIPADIPANAGFA
MMAR_3048|M.marinum_M GTATVRWPGPVFVASLLIALVGMMVVPGMKISYNDRYYIPRNLPSNVGYV
MAB_4746|M.abscessus_ATCC_1997 GTATVRWPGAVFAASSAIALVGIAIMPTMKVSYNDRFYIPEDLPSNIGYT
*: **** .:: : :::**: :* . .*:** *:* :*:* *:
Mflv_3435|M.gilvum_PYR-GCK VADEHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQ
Mvan_3189|M.vanbaalenii_PYR-1 VADRHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQ
TH_3260|M.thermoresistible__bu AAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQ
MUL_0757|M.ulcerans_Agy99 AAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQ
MAV_2510|M.avium_104 AADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQ
Mb0458c|M.bovis_AF2122/97 AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ
Rv0450c|M.tuberculosis_H37Rv AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ
MLBr_02378|M.leprae_Br4923 AADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQ
MSMEG_0382|M.smegmatis_MC2_155 AADRHFSQARMTPDILMVESDHDMRNPTDFLVLNKIAKAIFKVRGVSRVQ
MMAR_3048|M.marinum_M AAEQHFSAARLNPDILMIEGDHDMRNSSDMILLDRIAKEVFRAPGIARVQ
MAB_4746|M.abscessus_ATCC_1997 AAERHFSSATMNPDILMIESDHDMRNTGDMIILDRIAKEVFRSPGIAMVQ
.*:.** * :.*::*::*.***:**. *:::::::*: :* *:. **
Mflv_3435|M.gilvum_PYR-GCK AITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANT
Mvan_3189|M.vanbaalenii_PYR-1 AITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANT
TH_3260|M.thermoresistible__bu GITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLM
MUL_0757|M.ulcerans_Agy99 AITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTN
MAV_2510|M.avium_104 AITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTT
Mb0458c|M.bovis_AF2122/97 AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT
Rv0450c|M.tuberculosis_H37Rv AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT
MLBr_02378|M.leprae_Br4923 AITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAET
MSMEG_0382|M.smegmatis_MC2_155 GITRPEGTPIERTSIPFLLSLQSAGQVQATNFQKQRIGDMLKQVDDMNMM
MMAR_3048|M.marinum_M SITRPLGSPIEHSSIPFQVSMQALPIQQNLKFMKERTADMLKMSDDLGAM
MAB_4746|M.abscessus_ATCC_1997 SITRPLGGPIEHTSIPFQISAQSIPIQQNLQFMKDRAADMLSMSKDLDAL
.**** * .:.::**** :* * :: :: .:* . :
Mflv_3435|M.gilvum_PYR-GCK IKTMEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIR
Mvan_3189|M.vanbaalenii_PYR-1 IATMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIR
TH_3260|M.thermoresistible__bu IDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIR
MUL_0757|M.ulcerans_Agy99 IDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIR
MAV_2510|M.avium_104 IDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMR
Mb0458c|M.bovis_AF2122/97 IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR
Rv0450c|M.tuberculosis_H37Rv IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR
MLBr_02378|M.leprae_Br4923 IASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIR
MSMEG_0382|M.smegmatis_MC2_155 IGVMKTTYGVLQELAATTHSLNGSTHELRDVARDLRGSIAIFDDLLRPIR
MMAR_3048|M.marinum_M IASMERMQGLLGQMSGTTHRMVGDMGEMRVTLNEMRDHLADFDDFARPFR
MAB_4746|M.abscessus_ATCC_1997 IGAMERMQSLLGQMSSATHRMSANMTDAKTTLEEIRDHLADFDDVVRPLR
* : : : . : . .:*. :: *:*. **:*
Mflv_3435|M.gilvum_PYR-GCK NYFYWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMP
Mvan_3189|M.vanbaalenii_PYR-1 NYFYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMP
TH_3260|M.thermoresistible__bu NYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMP
MUL_0757|M.ulcerans_Agy99 SYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMP
MAV_2510|M.avium_104 SYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMP
Mb0458c|M.bovis_AF2122/97 SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP
Rv0450c|M.tuberculosis_H37Rv SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP
MLBr_02378|M.leprae_Br4923 SYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMP
MSMEG_0382|M.smegmatis_MC2_155 NYFYWEPHCYNIPICWSLRSIFDAMDGVDRLNDELQVLVDNMDRLDALVP
MMAR_3048|M.marinum_M GYLYWEQHCFNIPVCWASRSVFDAIDGVDKFSENMDALIGDMNDVDSILP
MAB_4746|M.abscessus_ATCC_1997 NYFYWEQHCFDLPACSAIRSVFDALDGVDAFSDKMRALTTDIGNVDAVIP
.*:*** **:.:* * : **:**::**:: : : : : : :: ::*
Mflv_3435|M.gilvum_PYR-GCK QMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDD
Mvan_3189|M.vanbaalenii_PYR-1 QMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDD
TH_3260|M.thermoresistible__bu QMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQ
MUL_0757|M.ulcerans_Agy99 QMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDS
MAV_2510|M.avium_104 QMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDA
Mb0458c|M.bovis_AF2122/97 QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA
Rv0450c|M.tuberculosis_H37Rv QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA
MLBr_02378|M.leprae_Br4923 QMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDT
MSMEG_0382|M.smegmatis_MC2_155 ELVAQFPEYIASMETFRELTLTSYSTFSGLLQQMDEQTEDVTAMGQAFDA
MMAR_3048|M.marinum_M RMQAEFPSMIAVATSMRGTLLTLHSSFSGLVTQMSRMTDTASAMGQAFDA
MAB_4746|M.abscessus_ATCC_1997 QMAAQLPPIIAVARSMQDTLLTMHSSFSNLITQMAHMTDTASAMGQAFDA
.: :* : :: *: : . * . :**:***
Mflv_3435|M.gilvum_PYR-GCK SMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGV
Mvan_3189|M.vanbaalenii_PYR-1 SMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGV
TH_3260|M.thermoresistible__bu ARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGL
MUL_0757|M.ulcerans_Agy99 SRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGI
MAV_2510|M.avium_104 SKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGI
Mb0458c|M.bovis_AF2122/97 AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI
Rv0450c|M.tuberculosis_H37Rv AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI
MLBr_02378|M.leprae_Br4923 AKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGI
MSMEG_0382|M.smegmatis_MC2_155 AKNDDTFFLPPEVFDNPDFKRAMTSFLSPDGKAARFIISHNGDPATPEGI
MMAR_3048|M.marinum_M SKADDYFYLPPEAFDNPDFQRGLKLFLSSDGKAARFIITHDSDPATPKGI
MAB_4746|M.abscessus_ATCC_1997 SRSGDYFYLPPEAFQNPDFQRGLKLFLSPDGTAARFIITHDRDPATPAGI
: .* *:**** *.* :*::.: *:*.** *.**** * ** : *:
Mflv_3435|M.gilvum_PYR-GCK AKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIA
Mvan_3189|M.vanbaalenii_PYR-1 AKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGIS
TH_3260|M.thermoresistible__bu AKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIA
MUL_0757|M.ulcerans_Agy99 NHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGIS
MAV_2510|M.avium_104 SHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGIS
Mb0458c|M.bovis_AF2122/97 KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS
Rv0450c|M.tuberculosis_H37Rv KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS
MLBr_02378|M.leprae_Br4923 ASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGIS
MSMEG_0382|M.smegmatis_MC2_155 SRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGSTYDLLIAGIA
MMAR_3048|M.marinum_M AAVKPELNAARQAVKGTPLADAKFYLTGTAAIYNDIQTGSKYDILIVGIA
MAB_4746|M.abscessus_ATCC_1997 STVTSELEAAHQAVKGTALTDAKFYLAGTAAIYRDIQSGSRYDLLIVGIA
: ** :::***.* .: .** **.. .* . * :*::*..*:
Mflv_3435|M.gilvum_PYR-GCK ALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLH
Mvan_3189|M.vanbaalenii_PYR-1 ALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELH
TH_3260|M.thermoresistible__bu AVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMH
MUL_0757|M.ulcerans_Agy99 ALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELH
MAV_2510|M.avium_104 SLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELH
Mb0458c|M.bovis_AF2122/97 SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH
Rv0450c|M.tuberculosis_H37Rv SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH
MLBr_02378|M.leprae_Br4923 SLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELH
MSMEG_0382|M.smegmatis_MC2_155 AMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLLWQYILGIHLH
MMAR_3048|M.marinum_M ALTLIFVVMVIITRALVASLVIVGTVLLSLGAAFGLSVLVWQHILGLDLN
MAB_4746|M.abscessus_ATCC_1997 AVTLIFAVMMIITRAFVASLAIVGTVLLSLGAAFGISVLVWQHIFGLELN
:: *** :*:*:**..:*: .***** ***.*:**:***.**::.. ::
Mflv_3435|M.gilvum_PYR-GCK WMVLAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVT
Mvan_3189|M.vanbaalenii_PYR-1 WMVLAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVT
TH_3260|M.thermoresistible__bu WMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVT
MUL_0757|M.ulcerans_Agy99 WLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVT
MAV_2510|M.avium_104 WMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVT
Mb0458c|M.bovis_AF2122/97 WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT
Rv0450c|M.tuberculosis_H37Rv WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT
MLBr_02378|M.leprae_Br4923 YLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVT
MSMEG_0382|M.smegmatis_MC2_155 WMVLAMSVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVRAMGGTGKVVT
MMAR_3048|M.marinum_M WIAPVFGVIILLAVGSDYNLLLVSRFQEEIGAGLKTGIIRSMGETGGVVT
MAB_4746|M.abscessus_ATCC_1997 WIAPVFGLIILLAVGSDYNLLLVSRFQEEIGAGLKTGIIRSMGGTGGVVT
::. :.:*:*****:*****:*:*:::*: **: **::*:** :* ***
Mflv_3435|M.gilvum_PYR-GCK AAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAAL
Mvan_3189|M.vanbaalenii_PYR-1 AAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAAL
TH_3260|M.thermoresistible__bu AAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATL
MUL_0757|M.ulcerans_Agy99 AAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAAL
MAV_2510|M.avium_104 SAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAAL
Mb0458c|M.bovis_AF2122/97 NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL
Rv0450c|M.tuberculosis_H37Rv NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL
MLBr_02378|M.leprae_Br4923 NAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAAL
MSMEG_0382|M.smegmatis_MC2_155 SAGLVFAGTMAAMVVSDLRIIGQIGTTIGLGLLFDTMIVRSFMTPSIAAL
MMAR_3048|M.marinum_M AAGLVFAFTMLSMVASDLRSIGQAGSTIGLGLLFDTLIVRSLMTPSVAAL
MAB_4746|M.abscessus_ATCC_1997 SAGLVFAFTMMSMVASDLSSIGQAGSTIGLGLLFDTLIVRSLMTPSLAGL
*****. ** : .*:* :.* *:***:******:::*::* **:* *
Mflv_3435|M.gilvum_PYR-GCK LGPWFWWPQRVRTRPVPAPWPRSGGLQSDPSEGVRA--------------
Mvan_3189|M.vanbaalenii_PYR-1 LGPWFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV--------------
TH_3260|M.thermoresistible__bu LGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV--------------
MUL_0757|M.ulcerans_Agy99 LGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV----------------
MAV_2510|M.avium_104 LGKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA----------------
Mb0458c|M.bovis_AF2122/97 LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------
Rv0450c|M.tuberculosis_H37Rv LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------
MLBr_02378|M.leprae_Br4923 LGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD--------------
MSMEG_0382|M.smegmatis_MC2_155 LGRWFWWPQKVRPRPASALLEPYGPRPLVRALLEGPSGAASPGGPGGRLS
MMAR_3048|M.marinum_M LGRWFWWPLRVRPRPASYMLRPFGPRRLVRSLLLGEPTDVATSQPAGYGG
MAB_4746|M.abscessus_ATCC_1997 LGPWFWWPLRVRTGPT-AEARPNGRRPYTQEGILNIAT------------
** ***** * *
Mflv_3435|M.gilvum_PYR-GCK -----------------------------
Mvan_3189|M.vanbaalenii_PYR-1 -----------------------------
TH_3260|M.thermoresistible__bu -----------------------------
MUL_0757|M.ulcerans_Agy99 -----------------------------
MAV_2510|M.avium_104 -----------------------------
Mb0458c|M.bovis_AF2122/97 -----------------------------
Rv0450c|M.tuberculosis_H37Rv -----------------------------
MLBr_02378|M.leprae_Br4923 -----------------------------
MSMEG_0382|M.smegmatis_MC2_155 DDDTPTGPMRTR-----------------
MMAR_3048|M.marinum_M SPERSNGDPATVPAAVPAPETGGADGSAR
MAB_4746|M.abscessus_ATCC_1997 GPER-------------------------