For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RSVAHVVIGSGVAISGACLCLSLTTLDYFRTLGPPCFAAMVVAVISALTLGPALLTLGSKVPWLSEPAKT SPAWRKLGTAIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKSVESSQGYAAADRHFQPSQLSI DTLYIKADHDMRNTTDMISLDRLAKNIVRTPGISMVQSITRPNGRPLEHASLPYAMGSMGTKIGQNLGFL KDRVADIDAIAARMGDMIASTEKMAGLTRQLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPIRNYL YWEPHCFDIPMCWAMRSLNESLDSIDETTQYLGPMVDGLTKISTATPQMITQLNAMVQNMTVMQRLTLTT QSLLHATVTQMEPMVNPMVDMAQAFDNAKNDDFFFLPPDSFKTKDFQSGLKFMMTPDGKGARIMIYHQGE AMSPEGIDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMMLATFGLVFLIVMAIT RTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIELHWLTLPIAFIVLVGVGCDYNLLLLSRYREELSAG IRTGLIRTIAGSGNVAVTAAFVLAGTMLAMLSSDVVNIGQAGATICIGLVFDMMIVRLFLVMPLARLLGP WFWWPQKLPRRQPVQLRGTPGPGPQAISEAGPHV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2570c | - | - | 100% (665) | MmpL family membrane protein |
| M. abscessus ATCC 19977 | MAB_0478 | - | 0.0 | 88.07% (654) | membrane protein MmpL |
| M. abscessus ATCC 19977 | MAB_2650 | - | e-180 | 47.38% (650) | MmpL family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1583 | mmpL6 | 1e-159 | 41.46% (656) | transmembrane transport protein MmpL6 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 1e-162 | 41.53% (655) | transport protein |
| M. tuberculosis H37Rv | Rv0402c | mmpL1 | 1e-163 | 42.39% (644) | transmembrane transport protein MmpL1 |
| M. leprae Br4923 | MLBr_02378 | - | 1e-156 | 41.78% (639) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_3744 | mmpL4_1 | 1e-164 | 42.32% (638) | transmembrane transport protein MmpL4_1 |
| M. avium 104 | MAV_1755 | - | 1e-160 | 41.76% (649) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0185 | - | 1e-165 | 43.71% (652) | MmpL6 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 1e-157 | 40.85% (661) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 1e-165 | 42.63% (638) | transmembrane transport protein MmpL4_1 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 1e-162 | 41.59% (654) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3744|M.marinum_M MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
MUL_3688|M.ulcerans_Agy99 MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
MAV_1755|M.avium_104 MSDASNKTQPDLSAADTGPINVKGLS----KAERGHRPYLPHAIRIFAVP
Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAAHGPHRS----------------FIPRMIRLFAVP
Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRP----------------FIPRMIRLFAVP
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHG----------PSFISTWIRRLSLP
MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKPP----------------------FVARMIHRFAVP
Mb1583|M.bovis_AF2122/97 -------MSNHHRPRP----------------------WLPHTIRRLSLP
Rv0402c|M.tuberculosis_H37Rv ---MRSQRLAGHLSAA------------------------ARTIHALSLP
MSMEG_0185|M.smegmatis_MC2_155 -MPGQVRMSAHRAGRP----------------------FFARTVRVLAVP
MAB_2570c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3744|M.marinum_M IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
MUL_3688|M.ulcerans_Agy99 IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
MAV_1755|M.avium_104 IILGWLFVTVLVNVIVPTLEKVGEAHSAPMTPLDAPSMKAMMRLGHNFHE
Mflv_3435|M.gilvum_PYR-GCK IILGWIALIVVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEE
Mvan_3189|M.vanbaalenii_PYR-1 IILGWIALIVILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFRE
TH_3260|M.thermoresistible__bu IIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDE
MLBr_02378|M.leprae_Br4923 IILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNE
Mb1583|M.bovis_AF2122/97 ILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVFHE
Rv0402c|M.tuberculosis_H37Rv IILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQ
MSMEG_0185|M.smegmatis_MC2_155 IIVFWGLLAVTTNTFIPQVEHVADELAGPMIPNYAPSQVALLHIGEKFQE
MAB_2570c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3744|M.marinum_M FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
MUL_3688|M.ulcerans_Agy99 FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
MAV_1755|M.avium_104 FDSNSTVMIVLEGQQPLGPDAHKYYDNLIRQLRQDPKHIQHIQDFWGDRL
Mflv_3435|M.gilvum_PYR-GCK GDSDSSVMIVFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPL
Mvan_3189|M.vanbaalenii_PYR-1 GDSDSSVMIVFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPL
TH_3260|M.thermoresistible__bu GSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPL
MLBr_02378|M.leprae_Br4923 GNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPL
Mb1583|M.bovis_AF2122/97 FDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGDPL
Rv0402c|M.tuberculosis_H37Rv FDSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPL
MSMEG_0185|M.smegmatis_MC2_155 SDSTNLTMLVFEADRPLDDGDHRYYDDLVRRLQADTEHVQYVMDLWGKPI
MAB_2570c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3744|M.marinum_M TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTH---EPAG
MUL_3688|M.ulcerans_Agy99 TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTH---EPAG
MAV_1755|M.avium_104 TAAGAQSADAKGAYVQVNLAGNQGTTLANESVDAVRKVIDENK---APPG
Mflv_3435|M.gilvum_PYR-GCK TASGSQSNDGKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPG
Mvan_3189|M.vanbaalenii_PYR-1 TASGSQSNDGKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPG
TH_3260|M.thermoresistible__bu TATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEG
MLBr_02378|M.leprae_Br4923 TAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPG
Mb1583|M.bovis_AF2122/97 TAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP---PPAG
Rv0402c|M.tuberculosis_H37Rv TAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSVP---PPPG
MSMEG_0185|M.smegmatis_MC2_155 TAAGAQSVDGKASFVLLRLAGNIGQLEANESVDAVRDIIADDA---PPQG
MAB_2570c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3744|M.marinum_M VKAYVTGPAALSDDMHLIGNASLAKITMFTLGAIAVMLLLVYRSIVTTVI
MUL_3688|M.ulcerans_Agy99 VKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVI
MAV_1755|M.avium_104 VKAYVTGPAALSDDMHIIGNASLAKITLFTLGAIAIMLLLVYRSIVTTLV
Mflv_3435|M.gilvum_PYR-GCK VRAFVTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLI
Mvan_3189|M.vanbaalenii_PYR-1 VRAFVTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLL
TH_3260|M.thermoresistible__bu VQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLI
MLBr_02378|M.leprae_Br4923 ITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVIL
Mb1583|M.bovis_AF2122/97 VKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVVTMVL
Rv0402c|M.tuberculosis_H37Rv IKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALI
MSMEG_0185|M.smegmatis_MC2_155 LKVYVSGAAPLASDTLSTANSSLNNITIFTIILIVVMLLLVYRSAACLLV
MAB_2570c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3744|M.marinum_M QLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFL
MUL_3688|M.ulcerans_Agy99 QLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFL
MAV_1755|M.avium_104 QLFMTFVALACSRGVVAVLAYHNAFGLTTFAANILTMLAIAAGTDYGIFL
Mflv_3435|M.gilvum_PYR-GCK TLVMVVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFL
Mvan_3189|M.vanbaalenii_PYR-1 TLVMVVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFL
TH_3260|M.thermoresistible__bu ALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFL
MLBr_02378|M.leprae_Br4923 LLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFI
Mb1583|M.bovis_AF2122/97 VLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAIFV
Rv0402c|M.tuberculosis_H37Rv MLLTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFL
MSMEG_0185|M.smegmatis_MC2_155 PLPAVLIEMLVAKGVIATLGHFGLIPLSSFAVNVVVALTLGAGTDYGIFL
MAB_2570c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3744|M.marinum_M VGRYQEARQAGEDREDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPW
MUL_3688|M.ulcerans_Agy99 VGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPW
MAV_1755|M.avium_104 IGRYQEALAAGEDRESAYYTTFKGVAPVVLGSGLTIAGATYCLSFSRLPW
Mflv_3435|M.gilvum_PYR-GCK IGRYQEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPY
Mvan_3189|M.vanbaalenii_PYR-1 IGRYQEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPY
TH_3260|M.thermoresistible__bu IGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPY
MLBr_02378|M.leprae_Br4923 TGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPY
Mb1583|M.bovis_AF2122/97 LGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRLPY
Rv0402c|M.tuberculosis_H37Rv VGRYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPY
MSMEG_0185|M.smegmatis_MC2_155 LGRYHEARQSGESREDAYFTAYRSVAPIIIGSGLTIAGACFCLSLARLDY
MAB_2570c|M.abscessus_ATCC_199 ---------------------MRSVAHVVIGSGVAISGACLCLSLTTLDY
.. :::.**::::** **.:: : :
MMAR_3744|M.marinum_M FNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHLFESKRAANRGRLWRR
MUL_3688|M.ulcerans_Agy99 FNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGRLWRR
MAV_1755|M.avium_104 FNTMGAPVAIGMLVVVLAGVTLGPAVVFVGSRFHFFE--RQAKRGRLWRR
Mflv_3435|M.gilvum_PYR-GCK FQTMGVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRK
Mvan_3189|M.vanbaalenii_PYR-1 FQTLGVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRK
TH_3260|M.thermoresistible__bu FQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRK
MLBr_02378|M.leprae_Br4923 FQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRR
Mb1583|M.bovis_AF2122/97 FQSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRRMRTRGWRR
Rv0402c|M.tuberculosis_H37Rv FNTLASPCAIGLVTVMLASLTLAPAIIAVASRFG-LFDPKRATTKRRWRR
MSMEG_0185|M.smegmatis_MC2_155 FHTMGPAVAISMLFTIAAALTLAPALLTLGSLLA-LFDPKRPTRGHLYRR
MAB_2570c|M.abscessus_ATCC_199 FRTLGPPCFAAMVVAVISALTLGPALLTLGSKVPWLSEPAKTSP--AWRK
*.::. . .:. : .: : : : :.: . :*:
MMAR_3744|M.marinum_M VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
MUL_3688|M.ulcerans_Agy99 VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
MAV_1755|M.avium_104 VGTAVVRWPAPVLAVSAAVVLVGMIALPSFHTSYNDRHYLPLSAPSNQGQ
Mflv_3435|M.gilvum_PYR-GCK IGAAIVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGY
Mvan_3189|M.vanbaalenii_PYR-1 IGAAVVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGY
TH_3260|M.thermoresistible__bu VGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGY
MLBr_02378|M.leprae_Br4923 IGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGF
Mb1583|M.bovis_AF2122/97 IGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANIGY
Rv0402c|M.tuberculosis_H37Rv IGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGY
MSMEG_0185|M.smegmatis_MC2_155 IGTSVVRWPKPIFVASAAVVMVGAVFVPSYRVNYDDRAYQPVDAAANLGF
MAB_2570c|M.abscessus_ATCC_199 LGTAIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKSVESSQGY
:*: :.:** .:: : : : :. : ..*. * * * :. *
MMAR_3744|M.marinum_M AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
MUL_3688|M.ulcerans_Agy99 AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
MAV_1755|M.avium_104 EAANRHFSEARMNPDLLMIESDHDMRNPADMLVLDRVAKNEMRTLGIAMV
Mflv_3435|M.gilvum_PYR-GCK AVADEHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARV
Mvan_3189|M.vanbaalenii_PYR-1 AVADRHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARV
TH_3260|M.thermoresistible__bu EAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRV
MLBr_02378|M.leprae_Br4923 AAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV
Mb1583|M.bovis_AF2122/97 MAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPGIGLV
Rv0402c|M.tuberculosis_H37Rv LASDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARV
MSMEG_0185|M.smegmatis_MC2_155 QAADRHFNQSKLFSEMLMIETDHDMRNSADFISLDRVAKALIRLPGVAMV
MAB_2570c|M.abscessus_ATCC_199 AAADRHFQPSQLSIDTLYIKADHDMRNTTDMISLDRLAKNIVRTPGISMV
.::.** ::: : * ::::**:**.:*:: ::::*: .: *:. :
MMAR_3744|M.marinum_M QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
MUL_3688|M.ulcerans_Agy99 QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
MAV_1755|M.avium_104 QDITRPLGIPIQHSSIPFQNSVQSQTTMQNMGFLKERMNDILKMADDLQT
Mflv_3435|M.gilvum_PYR-GCK QAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMAN
Mvan_3189|M.vanbaalenii_PYR-1 QAITRPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMAN
TH_3260|M.thermoresistible__bu QGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQL
MLBr_02378|M.leprae_Br4923 QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE
Mb1583|M.bovis_AF2122/97 QAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAEELGK
Rv0402c|M.tuberculosis_H37Rv QSITRPLGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQR
MSMEG_0185|M.smegmatis_MC2_155 QSITRPLGRPLEHATIPYLFTTQGSTNGQQLPFSEQANENTDRQAEIQAR
MAB_2570c|M.abscessus_ATCC_199 QSITRPNGRPLEHASLPYAMGSMGTKIGQNLGFLKDRVADIDAIAARMGD
* :*** * .:.*:::*: . .: : :
MMAR_3744|M.marinum_M LIDTTERMYAVMRDLDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
MUL_3688|M.ulcerans_Agy99 LIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
MAV_1755|M.avium_104 QIDTTQRQYEVSMDLANAADDSAKTTAVTSQITDSLRDHIADFDDTFRPI
Mflv_3435|M.gilvum_PYR-GCK TIKTMEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPI
Mvan_3189|M.vanbaalenii_PYR-1 TIATMEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPI
TH_3260|M.thermoresistible__bu MIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPI
MLBr_02378|M.leprae_Br4923 TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI
Mb1583|M.bovis_AF2122/97 TIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDFFRPI
Rv0402c|M.tuberculosis_H37Rv MIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFWRPL
MSMEG_0185|M.smegmatis_MC2_155 SVEVLQHVITITQQMSAELHSTVLTFENLKEVTDEVNEGISNLDDFLRPL
MAB_2570c|M.abscessus_ATCC_199 MIASTEKMAGLTRQLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPI
: : : : .:.: ::::** **:
MMAR_3744|M.marinum_M RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQHTAGLT
MUL_3688|M.ulcerans_Agy99 RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGLT
MAV_1755|M.avium_104 RTYFYWEKHCYDIPVCIGLRSLFDTFDGFDQLAEQFHYLTTDIAHTAKAS
Mflv_3435|M.gilvum_PYR-GCK RNYFYWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLM
Mvan_3189|M.vanbaalenii_PYR-1 RNYFYWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLM
TH_3260|M.thermoresistible__bu RNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLM
MLBr_02378|M.leprae_Br4923 RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM
Mb1583|M.bovis_AF2122/97 RSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAAIQ
Rv0402c|M.tuberculosis_H37Rv RSFTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQ
MSMEG_0185|M.smegmatis_MC2_155 KNYFYWEPHCFDIPVCFAMRSLFDSLDGIDSLDEQIGNAVVSFEAIDRLL
MAB_2570c|M.abscessus_ATCC_199 RNYLYWEPHCFDIPMCWAMRSLNESLDSIDETTQYLGPMVDGLTKISTAT
:.: *** **:::* * .:**: :::*..: : :
MMAR_3744|M.marinum_M SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
MUL_3688|M.ulcerans_Agy99 SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
MAV_1755|M.avium_104 RDLTALFPTLITTLKTTRGITLTLYQTFKAMIDQMEAMSNTAVVMGQSFD
Mflv_3435|M.gilvum_PYR-GCK PQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFD
Mvan_3189|M.vanbaalenii_PYR-1 PQMVALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFD
TH_3260|M.thermoresistible__bu PQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFD
MLBr_02378|M.leprae_Br4923 PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD
Mb1583|M.bovis_AF2122/97 PQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQAFD
Rv0402c|M.tuberculosis_H37Rv RQLLAQLDPTIATMQTVKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFD
MSMEG_0185|M.smegmatis_MC2_155 PQMITQLERMIADSRALLGVITNNYGPAHLQSTQTDQTYYDQINVGNDFD
MAB_2570c|M.abscessus_ATCC_199 PQMITQLNAMVQNMTVMQRLTLTTQSLLHATVTQMEPMVNPMVDMAQAFD
:: : : : * :.. **
MMAR_3744|M.marinum_M ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
MUL_3688|M.ulcerans_Agy99 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
MAV_1755|M.avium_104 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMSPEG
Mflv_3435|M.gilvum_PYR-GCK DSMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEG
Mvan_3189|M.vanbaalenii_PYR-1 DSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEG
TH_3260|M.thermoresistible__bu QARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEG
MLBr_02378|M.leprae_Br4923 TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG
Mb1583|M.bovis_AF2122/97 AAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATPEG
Rv0402c|M.tuberculosis_H37Rv AANNDDSFYLPPEAFQNPDFQRGLKLFLSPDGTCARFVITHRGDPASAEG
MSMEG_0185|M.smegmatis_MC2_155 AARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAMAPEG
MAB_2570c|M.abscessus_ATCC_199 NAKNDDFFFLPPDSFKTKDFQSGLKFMMTPDGKGARIMIYHQGEAMSPEG
: .** *::* : *.. *.: .:. :::.** .*:.* *.*:. : *
MMAR_3744|M.marinum_M ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
MUL_3688|M.ulcerans_Agy99 ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
MAV_1755|M.avium_104 IKRVDAERTAAQEGLKQSSLSDARVYLGGTAATFKDMADGEKYDLMIAVV
Mflv_3435|M.gilvum_PYR-GCK VAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGI
Mvan_3189|M.vanbaalenii_PYR-1 VAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGI
TH_3260|M.thermoresistible__bu LAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAI
MLBr_02378|M.leprae_Br4923 IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI
Mb1583|M.bovis_AF2122/97 ISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIAGI
Rv0402c|M.tuberculosis_H37Rv ISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIAVV
MSMEG_0185|M.smegmatis_MC2_155 IEHVEQFPDAIKMALKETSLAGAKIYIGGAASNNLDIKTYAASDLLIVAI
MAB_2570c|M.abscessus_ATCC_199 IDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMML
: : * .:* :.: : :.*::: *: *:: :
MMAR_3744|M.marinum_M SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
MUL_3688|M.ulcerans_Agy99 SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
MAV_1755|M.avium_104 SALTLIFMIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIRI
Mflv_3435|M.gilvum_PYR-GCK AALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPL
Mvan_3189|M.vanbaalenii_PYR-1 SALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTEL
TH_3260|M.thermoresistible__bu AAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEM
MLBr_02378|M.leprae_Br4923 SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL
Mb1583|M.bovis_AF2122/97 AALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGIQL
Rv0402c|M.tuberculosis_H37Rv ASLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHMPL
MSMEG_0185|M.smegmatis_MC2_155 AAFVLIFLIMLYLTRSLVAALVIPGTVAFSFAGAFGLSVMMWQHLIGLPL
MAB_2570c|M.abscessus_ATCC_199 ATFGLVFLIVMAITRTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIEL
::. *:::*:: :**:...: :: *.. *: .::*::*:.*: :. :
MMAR_3744|M.marinum_M HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
MUL_3688|M.ulcerans_Agy99 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
MAV_1755|M.avium_104 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHGGLKTGIIRSMAGTGGVV
Mflv_3435|M.gilvum_PYR-GCK HWMVLAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVV
Mvan_3189|M.vanbaalenii_PYR-1 HWMVLAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVV
TH_3260|M.thermoresistible__bu HWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVV
MLBr_02378|M.leprae_Br4923 HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV
Mb1583|M.bovis_AF2122/97 YWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGGVV
Rv0402c|M.tuberculosis_H37Rv HWLVLPMAIIVMLAVGSDYNLLLIARFQEEIGAGLKTGMIRAMAGTGRVV
MSMEG_0185|M.smegmatis_MC2_155 HWLILPLSFIILVAVGSDYNLLLISRVKEETGAGLNTGLIRALGSTGAVV
MAB_2570c|M.abscessus_ATCC_199 HWLTLPIAFIVLVGVGCDYNLLLLSRYREELSAGIRTGLIRTIAGSGNVA
::: .::.*:::.**.*****:::* ::* .*: **:**::..:* *.
MMAR_3744|M.marinum_M TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MUL_3688|M.ulcerans_Agy99 TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MAV_1755|M.avium_104 TAAGLVFAFTMAAMLGSELRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
Mflv_3435|M.gilvum_PYR-GCK TAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAA
Mvan_3189|M.vanbaalenii_PYR-1 TAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAA
TH_3260|M.thermoresistible__bu TAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIAT
MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
Mb1583|M.bovis_AF2122/97 TAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSIAV
Rv0402c|M.tuberculosis_H37Rv TIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRSYMTPALAT
MSMEG_0185|M.smegmatis_MC2_155 TSAGLVFAFTMLSMLVSDLRTIGQLGTTVCIGLLLDTMIVRSLVVPCLLR
MAB_2570c|M.abscessus_ATCC_199 VTAAFVLAGTMLAMLSSDVVNIGQAGATICIGLVFDMMIVRLFLVMPLAR
. *.:*:. ** : *:: :** *:*: :**::* :::* : :
MMAR_3744|M.marinum_M LLGRWFWWPQVVH-----PRGDNARPRVAAPTH-----------------
MUL_3688|M.ulcerans_Agy99 LLGRWFWWPQVVH-----PRGDNARPRVAAPTH-----------------
MAV_1755|M.avium_104 LLGRWFWWPMVVH-----PRGDNARRPVPASS------------------
Mflv_3435|M.gilvum_PYR-GCK LLGPWFWWPQRVR---TRPVPAPWPRSGGLQSDPSEGVRA----------
Mvan_3189|M.vanbaalenii_PYR-1 LLGPWFWWPQRVR---TRPVPAPWPRPGGLQSDPSEGVKV----------
TH_3260|M.thermoresistible__bu LLGRWFWWPQFVR---KRPVPQPWPSVPPRGPATTDRVSV----------
MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGR---TRPLLTVAAPVG-LPPDRSLVYSD----------
Mb1583|M.bovis_AF2122/97 LLGRWFWWPQRVR---PRPASRMLRPYGPRPVVRELLLREGNDDPRTQVA
Rv0402c|M.tuberculosis_H37Rv LLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ-----------
MSMEG_0185|M.smegmatis_MC2_155 LLGPWFWWPTFIR---QRPLRQAVRQRERADVV-----------------
MAB_2570c|M.abscessus_ATCC_199 LLGPWFWWPQKLPR--RQPVQLRGTPGPGPQAISEAGPHV----------
*** ***** *
MMAR_3744|M.marinum_M ---
MUL_3688|M.ulcerans_Agy99 ---
MAV_1755|M.avium_104 ---
Mflv_3435|M.gilvum_PYR-GCK ---
Mvan_3189|M.vanbaalenii_PYR-1 ---
TH_3260|M.thermoresistible__bu ---
MLBr_02378|M.leprae_Br4923 ---
Mb1583|M.bovis_AF2122/97 THR
Rv0402c|M.tuberculosis_H37Rv ---
MSMEG_0185|M.smegmatis_MC2_155 ---
MAB_2570c|M.abscessus_ATCC_199 ---