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DRLVYVGEEGEVASGPRQRLIDSAIAMMRERGVHATGLADLLKRSGTARNSIYQHFPEGKAELIAAAERE ASDLANGFLDALRARGDAEYLLTRFIAWWVNQLEAHDFDTGCPHAAAALAGPGEEQIRAAAHDAFIGMRT RLAESFRDSGVAHDVDSLASLTVSAIEGALLQAQAARSVQPLREVERELIALIRARAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3924c | - | - | 100% (199) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4634c | - | 3e-22 | 37.16% (183) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1494 | - | 4e-22 | 35.29% (187) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 6e-22 | 37.70% (191) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 6e-21 | 32.80% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 6e-22 | 37.70% (191) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 8e-05 | 29.85% (67) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3560 | - | 3e-30 | 45.51% (167) | transcriptional regulatory protein |
| M. avium 104 | MAV_4948 | - | 1e-23 | 34.05% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3520 | - | 7e-24 | 37.70% (183) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3160 | - | 1e-25 | 38.58% (197) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_2793 | - | 4e-29 | 44.31% (167) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0275 | - | 4e-24 | 40.86% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3560|M.marinum_M -------------------------MTARER------------LIESAIE
MUL_2793|M.ulcerans_Agy99 -------------------------MTARER------------LIESAIE
MAB_3924c|M.abscessus_ATCC_199 -----------MDRLVYVGEEGEVASGPRQR------------LIDSAIA
Mb0202|M.bovis_AF2122/97 ------------------------MQGPRER------------MVVSAAL
Rv0196|M.tuberculosis_H37Rv ------------------------MQGPRER------------MVVSAAL
Mflv_3287|M.gilvum_PYR-GCK ------------------------MTTPRER------------MVVSAAL
MSMEG_3520|M.smegmatis_MC2_155 ------------------------MASPRER------------MVRSAAV
Mvan_0275|M.vanbaalenii_PYR-1 --------------------MSPRTSDARER------------MLDSAST
MAV_4948|M.avium_104 -------------MPTTKQQAPAKRGGTRTK------------MLASAAE
TH_3160|M.thermoresistible__bu -------------MGVEVTRRRDPQSGPRAA------------MLRSAVA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
.. :: *
MMAR_3560|M.marinum_M LLRRNGVAGTGLADLLEHSGTARRSVYVNFPGGKSELMTEATRTAGRLMD
MUL_2793|M.ulcerans_Agy99 LLRRNGVAGTGLADLLEHSGTARRSVYVNFPGGKSELMTEATRTAGRLMD
MAB_3924c|M.abscessus_ATCC_199 MMRERGVHATGLADLLKRSGTARNSIYQHFPEGKAELIAAAEREASDLAN
Mb0202|M.bovis_AF2122/97 LIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA
Rv0196|M.tuberculosis_H37Rv LIRERGAHATAISDVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAGEHVA
Mflv_3287|M.gilvum_PYR-GCK LIRERGAHPTAIADVLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAAEFMA
MSMEG_3520|M.smegmatis_MC2_155 LIRERGAHPTAIADVLAHSGAPRGSAYHYFPGGRTQLLCEAIDYASDHVT
Mvan_0275|M.vanbaalenii_PYR-1 LIREHGASGTSLDDILRHSRAPRGSVYHHFPGGRAQLIEEVVDRAGGALA
MAV_4948|M.avium_104 VMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILAEALRYSGDSIT
TH_3160|M.thermoresistible__bu LMRRQGVAATSFADVLADSGAPRGSIYHHFPAGKAQLIEEATRTAAAQLT
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSS-KLELYLAVLERHMNNLV
:: .* . : : : ..: * *. : :: .
MMAR_3560|M.marinum_M STLAS-IAAGGDQP--LVAFADSWKQTLRASDYAAGCPIVAAALGRTESP
MUL_2793|M.ulcerans_Agy99 STLAS-IAAGGGQP--LVAFADSWKQTLRASDYAAGCPIVAAALGRTESP
MAB_3924c|M.abscessus_ATCC_199 GFLDA-LRARGDAEYLLTRFIAWWVNQLEAHDFDTGCPHAAAALAGPGEE
Mb0202|M.bovis_AF2122/97 AMIN--EAEGG--LELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQ
Rv0196|M.tuberculosis_H37Rv AMIN--EAEGG--LELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQ
Mflv_3287|M.gilvum_PYR-GCK ERLS--RASSS--LRVLDDLFGYYRTQLQDSDFRAGCPVVAVAVESGDPD
MSMEG_3520|M.smegmatis_MC2_155 ARLD--RATDT--FALLDDMVARFRDQLLASDFRAGCPVVAVAVEAGDPE
Mvan_0275|M.vanbaalenii_PYR-1 AILG--DAGDATPATTFDVFISTWKAGLEASGFRAGCPVLAVAVETNDD-
MAV_4948|M.avium_104 ALID--QAAGRGGRALLREFVEYWERLLTEGGFTAGCPVVAAAIGCSEDE
TH_3160|M.thermoresistible__bu ERVARVLDEAADLPTALRELVGVWRDGLEAGDYAVGCPIVAAALGTERAA
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQRLHAAVQAFFDFIEHD--GQGYRLIFENDNITEPR
: : : : *
MMAR_3560|M.marinum_M ------SAADAAGEVFGAWQTVLAGRFRAQGVGDDTAESLAT-TVVAAVE
MUL_2793|M.ulcerans_Agy99 ------SAADVAGEVFGAWQTVLAGRFRAQGVGDDTAESLAT-TVVAAVE
MAB_3924c|M.abscessus_ATCC_199 ------QIRAAAHDAFIGMRTRLAESFRDSGVAHD-VDSLAS-LTVSAIE
Mb0202|M.bovis_AF2122/97 DRERMAPVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAV-LATSTLE
Rv0196|M.tuberculosis_H37Rv DRERMAPVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAV-LATSTLE
Mflv_3287|M.gilvum_PYR-GCK KPEQSAPVIERAAAALTRWSDIIEQRLIADGVPRADAAALAM-LVLTSFE
MSMEG_3520|M.smegmatis_MC2_155 KADSADAVRERAGAAFQRWIARITARLCDDGVPVERAEELAT-LITTSVE
Mvan_0275|M.vanbaalenii_PYR-1 ----APQLTEAAARAFGSWRDALNTVLRHQGVPPARARRLAT-LIVAAVE
MAV_4948|M.avium_104 ----GPKLSAEAGAILGRWCTALTRAFVNDGFDDADAASLAV-MSIAALE
TH_3160|M.thermoresistible__bu --------RDVAGVAFADLTGLISDKLVSDGMARRRANSVAV-LILTAME
MLBr_00815|M.leprae_Br4923 ------VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVD
. . . :* :.:
MMAR_3560|M.marinum_M GAVILCLAARSTDPLDRTVPMLQQLIAQHTSRPSG----------
MUL_2793|M.ulcerans_Agy99 GAVILCLAARSTDPLDRTVPMLQQLIAQHTSRPSG----------
MAB_3924c|M.abscessus_ATCC_199 GALLQAQAARSVQPLR---EVERELIALIRARAE-----------
Mb0202|M.bovis_AF2122/97 GAILLARVRRDLTPLDLVHRQLRNLLLAELPERSR----------
Rv0196|M.tuberculosis_H37Rv GAILLARVRRDLTPLDLVHRQLRNLLLAELPERSR----------
Mflv_3287|M.gilvum_PYR-GCK GAIVVARATRDLKPLDLVAGQLASLIDARTVTRRK----------
MSMEG_3520|M.smegmatis_MC2_155 GAVLVARTTRDVKPLELVHRQLREQLTAATGKKDRP---------
Mvan_0275|M.vanbaalenii_PYR-1 GAVALSRVERNTQPIDDVARELRALIRQATDAS------------
MAV_4948|M.avium_104 GGIVLSRSTRNAGPLHQVGEQLEFLIKAREFVVRNKIPGKQPGSR
TH_3160|M.thermoresistible__bu GALVLAQARRDPAALDAVVDELTLLCSGSAD--------------
MLBr_00815|M.leprae_Br4923 CARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL--------
. *