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PRNRQQIPRAERESAILEQAVELFAANGYRGTSVAAVGRAAGVAPAAVHWYYPTKDDLFAAAVTSIFDSV RERVEADPSINGEPYGELVALLSESQSYRNLHREAYERMEGSEAVRAAYEHVQSWLDERLLAAIAQRNRG GVNSELVADAAHVLFEGILISSRRLDRSAGELIGLVVDALVAVAVTKRGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4360c | - | - | 100% (191) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_4449c | - | 2e-11 | 31.78% (107) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2543c | - | 2e-09 | 29.88% (164) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 5e-11 | 26.49% (151) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0414 | - | 6e-10 | 24.65% (142) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 6e-11 | 26.49% (151) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 5e-10 | 34.12% (85) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0500 | - | 1e-10 | 26.21% (145) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4919 | - | 1e-11 | 26.76% (142) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0363 | - | 2e-09 | 25.67% (187) | TetR-family protein regulatory protein |
| M. thermoresistible (build 8) | TH_2602 | - | 5e-52 | 50.53% (188) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1163 | - | 4e-11 | 25.00% (188) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0257 | - | 4e-10 | 24.65% (142) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0244|M.bovis_AF2122/97 --MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPM
Rv0238|M.tuberculosis_H37Rv --MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQISKPM
MMAR_0500|M.marinum_M --MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPM
MUL_1163|M.ulcerans_Agy99 --MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAAQISKPM
MAV_4919|M.avium_104 --MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAQAQISKPM
MLBr_02568|M.leprae_Br4923 --MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPM
Mflv_0414|M.gilvum_PYR-GCK --MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPM
Mvan_0257|M.vanbaalenii_PYR-1 --MAGGTKRLPRAVREQQMLDAAVEIFSVNGYHETSMDAIAAEAQISKPM
MSMEG_0363|M.smegmatis_MC2_155 MGMAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAAAEISKPM
MAB_4360c|M.abscessus_ATCC_199 --MPRNRQQIPRAERESAILEQAVELFAANGYRGTSVAAVGRAAGVAPAA
TH_2602|M.thermoresistible__bu --VPRNNQTVPKAEREAAVLMRAVELFKAYGYRATSIAAVAKAAGLAPAA
:. . : :*:* ** :* **::* . **: **: ::. * :: .
Mb0244|M.bovis_AF2122/97 LYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLR
Rv0238|M.tuberculosis_H37Rv LYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLR
MMAR_0500|M.marinum_M LYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLR
MUL_1163|M.ulcerans_Agy99 LYLYYGSKEDLFGACLNREMSRFIDAVRADIDLSQSPKDLLRNAIVSFLR
MAV_4919|M.avium_104 LYLYYGSKEDLFGACLNRELGRFIDAVRADIDFQQSPNDMLRNTIASFMR
MLBr_02568|M.leprae_Br4923 LYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVSFLR
Mflv_0414|M.gilvum_PYR-GCK LYLYYGSKEELFGACLHRELTRFVDEVNSNIDFTAPPKELLRTAVLAFLN
Mvan_0257|M.vanbaalenii_PYR-1 LYLYYGSKEELFGACLNRELGRFVDEVNSNIDFSAAPKELLRTAVLAFLK
MSMEG_0363|M.smegmatis_MC2_155 LYLYYGSKEELFGACLDRELRRFVDTVRGQIDFSQSPKELLRTAVLAFLT
MAB_4360c|M.abscessus_ATCC_199 VHWYYPTKDDLFAAAVTSIFDSVRERVEADPSINGEPYGELVALLSESQS
TH_2602|M.thermoresistible__bu VHWYFPTKDDLFAAVLRHMIGETQRRIESDPDVAGDPYLELTTFLDLLAP
:: *: :*::**.* : : :... .. * * :
Mb0244|M.bovis_AF2122/97 YIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLT
Rv0238|M.tuberculosis_H37Rv YIDANRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLT
MMAR_0500|M.marinum_M YIDQNQASWIVMYTQAVSSQAFAQTVREGREQIVELVAGMLRAGTRSPRS
MUL_1163|M.ulcerans_Agy99 YIDQNQASWIVMYTQAVSSQAFAQTVREGREQIVELVAGMLRAGTRSPRS
MAV_4919|M.avium_104 YIDANRASWIVMYTQATSSQAFAHMVREGREQIIELVAGLMRAGSRTPRT
MLBr_02568|M.leprae_Br4923 YIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRP
Mflv_0414|M.gilvum_PYR-GCK YIDANRASWMVLYTQATSSQAFAHTVREGRERIIEIVGRLLRSGTRFPEP
Mvan_0257|M.vanbaalenii_PYR-1 YIDANRASWMVLYTQATSSQAFAHTVREGRERIIELVGRLLRSGTKFPEP
MSMEG_0363|M.smegmatis_MC2_155 YIDRNRASWMVLYTQATSSQAFAHTVREGRERIIDLVARLLSTGTRNPQP
MAB_4360c|M.abscessus_ATCC_199 YRNLHREAYERMEGSEAVRAAYEHVQSWLDERLLAAIAQRNRGGVN----
TH_2602|M.thermoresistible__bu YRSLHREAYERMDDSAALHAVYTETHDWLQERLMAVVSPELPADVD----
* . :: :: : . .: . ::: :. .
Mb0244|M.bovis_AF2122/97 DAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVD
Rv0238|M.tuberculosis_H37Rv DAEIEMMAVALVGAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVD
MMAR_0500|M.marinum_M DAEIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMIDLFWRGLKGAPSD
MUL_1163|M.ulcerans_Agy99 DAEIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMIDLLWRGLKGAPSD
MAV_4919|M.avium_104 DREHEMMAVALVGAGEAVANRLSTGDIDVDEAAALMIDLFWYGLKGSPEE
MLBr_02568|M.leprae_Br4923 DHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPAD
Mflv_0414|M.gilvum_PYR-GCK DTDFDMMAVALVGAGEAIASRVSTGDADVHEASELMINLFWRGLKGSPSA
Mvan_0257|M.vanbaalenii_PYR-1 DTDFELMAVALVGAGEAIASRVSTGDADVDEAAELMINLFWLGLKGAPSA
MSMEG_0363|M.smegmatis_MC2_155 DSDFEMMAVALVGAGEAIATRVSTGDADVDEAAELMINLFWRGLKGTPSD
MAB_4360c|M.abscessus_ATCC_199 -------SELVADAAHVLFEGILISSRRLDRSAGELIGLVVDALVAVAVT
TH_2602|M.thermoresistible__bu -------PAHVVDVANFFFEGLLVSVRRVDKPAAHYIDLVTSAVVGAAAA
. :..... . : . :...: *.*. .: . .
Mb0244|M.bovis_AF2122/97 R-------LETGH----------
Rv0238|M.tuberculosis_H37Rv R-------LETGH----------
MMAR_0500|M.marinum_M RE------IGSNFAAG-------
MUL_1163|M.ulcerans_Agy99 RE------IGSNFAAG-------
MAV_4919|M.avium_104 RE------AAAAQPEADRSGAGG
MLBr_02568|M.leprae_Br4923 RD------FGPSIVAG-------
Mflv_0414|M.gilvum_PYR-GCK ASDRDADATDATAVITS------
Mvan_0257|M.vanbaalenii_PYR-1 AD------VDATAVISS------
MSMEG_0363|M.smegmatis_MC2_155 AG------TPPVSAGSSG-----
MAB_4360c|M.abscessus_ATCC_199 KR-------GS------------
TH_2602|M.thermoresistible__bu RP-------RSGQQHPA------
.