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M. abscessus ATCC 19977 MAB_0987c (-)

annotation: membrane protein MmpL
coordinates: 994399 - 997269
length: 956

SANHAHESRAAKIVRRLAVPIVLFWVAIAAVTNATVPQLEVVGEERSAPLNAADAPSTLAMRHIGKVFNE
FDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHVQHVADYWGDPITAGGSQSKDGKAAYVQVYVA
GNQGEALSNESVDAVRRIIAETPAPDGIKAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVVYR
SLITTALVLAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIAAGTDYAIFFVGRYQEARSAGED
RPSAYQTMYKSTAHVIIGSGLTVAGALFCLSFTRLPYFQTLGVPAALGVLVTLAAALTLAPAVLVIAGRF
GLMEPKRAMRTRGWRRIGTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMPSSVPSNVGYAAAE
RHFSVARLNPELLMIETDFDMRNPAGMVLLERVAKSVLHARGVALVQSITRPLGTPITHSSIPFQISASS
ASQLMNLSQQQNQALYLSQQADQMTNTIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIANFD
DQFRPIRNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTGSLTKLDALQPKLVDLIPPQIAIQ
EKNRDLTLSNYAINNGTNTQNEESTRTATELGKAFDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKA
ARMIITHQGDPQTSEGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQKYDLLMAALASLG
LILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVVWQYIFGIPLYWVIFPLAVIILLAVGADYNLLLI
SRFKEETGAGLKTGIIRAIAGTGGVVTAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRSFL
TPAIATMLGRWFWWPINIRTRPAPKPFGPKPTGADDTTGPIPVSG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0987c--100% (956)membrane protein MmpL
M. abscessus ATCC 19977MAB_2301-0.055.17% (968) putative membrane protein, mmpL
M. abscessus ATCC 19977MAB_3150-0.055.85% (931) MmpL family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1583mmpL60.067.72% (945) transmembrane transport protein MmpL6
M. gilvum PYR-GCKMflv_4418-0.057.88% (926) transport protein
M. tuberculosis H37RvRv0450cmmpL40.058.15% (932) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.056.30% (929) hypothetical protein MLBr_02378
M. marinum MMMAR_0775-0.059.53% (934) MmpL family transport protein
M. avium 104MAV_3863-0.067.09% (945) MmpL4 protein
M. smegmatis MC2 155MSMEG_3496-0.055.67% (943) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.055.36% (943) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.054.16% (949) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.057.25% (931) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4418|M.gilvum_PYR-GCK          ---------------------------------MADAGRSGIGRIIRVLA
Mvan_1936|M.vanbaalenii_PYR-1       ---------------------------------MADAGRSGIGRIIHLLA
MSMEG_3496|M.smegmatis_MC2_155      ------------MSNP----SHDAPTDAMGVSGPKHARPGGIAKWIRVLA
TH_3260|M.thermoresistible__bu      -----------MTANPGHVRTDEAPTDRLDIKVSTHG-PSFISTWIRRLS
MUL_0757|M.ulcerans_Agy99           -----------MTATT-----TDTPTDVVPP--AEHPPRPFIPRMIRTFA
Rv0450c|M.tuberculosis_H37Rv        ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
MLBr_02378|M.leprae_Br4923          ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA
MMAR_0775|M.marinum_M               MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
Mb1583|M.bovis_AF2122/97            -------------------------------MSNHHRPRPWLPHTIRRLS
MAV_3863|M.avium_104                -------------------------------MTTDQATRSVVAQTIRRLS
MAB_0987c|M.abscessus_ATCC_199      -------------------------------MSANHAHESRAAKIVRRLA
                                                                                 :: ::

Mflv_4418|M.gilvum_PYR-GCK          VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF
Mvan_1936|M.vanbaalenii_PYR-1       VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF
MSMEG_3496|M.smegmatis_MC2_155      VPIILVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVF
TH_3260|M.thermoresistible__bu      LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF
MUL_0757|M.ulcerans_Agy99           VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF
Rv0450c|M.tuberculosis_H37Rv        VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923          VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
MMAR_0775|M.marinum_M               VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF
Mb1583|M.bovis_AF2122/97            LPILLFWVGVAAITNAAVPQLEVVGEAHNVAQSSPDDPSLQAMKRIGKVF
MAV_3863|M.avium_104                VPILLVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAMQHIGKVF
MAB_0987c|M.abscessus_ATCC_199      VPIVLFWVAIAAVTNATVPQLEVVGEERSAPLNAADAPSTLAMRHIGKVF
                                    :*::: *: : .     :*.*: *.: : .  ..    *  :* ::*  *

Mflv_4418|M.gilvum_PYR-GCK          EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD
Mvan_1936|M.vanbaalenii_PYR-1       DEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGD
MSMEG_3496|M.smegmatis_MC2_155      EEFKSNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGD
TH_3260|M.thermoresistible__bu      DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD
MUL_0757|M.ulcerans_Agy99           REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD
Rv0450c|M.tuberculosis_H37Rv        KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923          NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD
MMAR_0775|M.marinum_M               NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD
Mb1583|M.bovis_AF2122/97            HEFDSDSAAMIVLEGDKPLGNDAHRFYDTLLRNLSNDTKHVEHVQDFWGD
MAV_3863|M.avium_104                HEYDSDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEHVQNFWGD
MAB_0987c|M.abscessus_ATCC_199      NEFDSDSSAMVVLEGEKPLGAQAHQFYNTLVQRLNDDHEHVQHVADYWGD
                                     * .::*  *:::**:.***  *: :*: :: .*  *  :*: : : *.*

Mflv_4418|M.gilvum_PYR-GCK          PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---AP
Mvan_1936|M.vanbaalenii_PYR-1       PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---AP
MSMEG_3496|M.smegmatis_MC2_155      PLTASGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---AP
TH_3260|M.thermoresistible__bu      PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP
MUL_0757|M.ulcerans_Agy99           PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---AP
Rv0450c|M.tuberculosis_H37Rv        PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
MLBr_02378|M.leprae_Br4923          PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---AP
MMAR_0775|M.marinum_M               PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---AP
Mb1583|M.bovis_AF2122/97            PLTAAGSQSTDGKAAYVQVYLAGNQGEALSIESVDAVRDIVAHTP---PP
MAV_3863|M.avium_104                PLTAAGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIVEHTP---PP
MAB_0987c|M.abscessus_ATCC_199      PITAGGSQSKDGKAAYVQVYVAGNQGEALSNESVDAVRRIIAETP---AP
                                    *:** * ** ** ::***    ****   : *:: ::: ::       .*

Mflv_4418|M.gilvum_PYR-GCK          PGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATM
Mvan_1936|M.vanbaalenii_PYR-1       PGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATM
MSMEG_3496|M.smegmatis_MC2_155      PGVKAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTV
TH_3260|M.thermoresistible__bu      EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV
MUL_0757|M.ulcerans_Agy99           PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITA
Rv0450c|M.tuberculosis_H37Rv        PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
MLBr_02378|M.leprae_Br4923          PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV
MMAR_0775|M.marinum_M               PGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITV
Mb1583|M.bovis_AF2122/97            AGVKAYVTGAAPLMADQFQVGSKGTAKVTGITLVVIAVMLLFVYRSVVTM
MAV_3863|M.avium_104                PGVKAYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVYRS-VTA
MAB_0987c|M.abscessus_ATCC_199      DGIKAYVSGEAPTITDQFEVGNAGAAQVTIITFAVIAVMLLVVYRSLITT
                                     *: .:*:* :.  :*    .. .   :   :. **   ** *:**  * 

Mflv_4418|M.gilvum_PYR-GCK          VLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAI
Mvan_1936|M.vanbaalenii_PYR-1       VLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAI
MSMEG_3496|M.smegmatis_MC2_155      ILTLVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAI
TH_3260|M.thermoresistible__bu      LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI
MUL_0757|M.ulcerans_Agy99           AIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAI
Rv0450c|M.tuberculosis_H37Rv        VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
MLBr_02378|M.leprae_Br4923          ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI
MMAR_0775|M.marinum_M               ISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAI
Mb1583|M.bovis_AF2122/97            VLVLITVLIELAAARGIVAFLGNAGVIGLSTYSTNLLTLLVIAAGTDYAI
MAV_3863|M.avium_104                VFVLVTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAAGTDYAI
MAB_0987c|M.abscessus_ATCC_199      ALVLAMVMVELSAARGIVAALGHTGVIGLSTYATNLLTMLAIAAGTDYAI
                                       *  *     .:** :* *.    ***:.::..**. :.** ..**.*

Mflv_4418|M.gilvum_PYR-GCK          FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
Mvan_1936|M.vanbaalenii_PYR-1       FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
MSMEG_3496|M.smegmatis_MC2_155      FLIGRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRM
TH_3260|M.thermoresistible__bu      FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL
MUL_0757|M.ulcerans_Agy99           FLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRL
Rv0450c|M.tuberculosis_H37Rv        FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARM
MLBr_02378|M.leprae_Br4923          FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM
MMAR_0775|M.marinum_M               FVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRL
Mb1583|M.bovis_AF2122/97            FVLGRYHEARYAAQDRETAFYTMYRGTAHVVLGSGLTVAGAVYCLSFTRL
MAV_3863|M.avium_104                FFVGRYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLCLRFTRL
MAB_0987c|M.abscessus_ATCC_199      FFVGRYQEARSAGEDRPSAYQTMYKSTAHVIIGSGLTVAGALFCLSFTRL
                                    *  ***:***    .:  :: **: .* **::.**:*::**  ** *:*:

Mflv_4418|M.gilvum_PYR-GCK          PYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGW
Mvan_1936|M.vanbaalenii_PYR-1       PYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGW
MSMEG_3496|M.smegmatis_MC2_155      PYFQSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGW
TH_3260|M.thermoresistible__bu      PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW
MUL_0757|M.ulcerans_Agy99           PYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGW
Rv0450c|M.tuberculosis_H37Rv        PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
MLBr_02378|M.leprae_Br4923          PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW
MMAR_0775|M.marinum_M               PYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGW
Mb1583|M.bovis_AF2122/97            PYFQSLGIPASIGVMIALAAALSLAPSVLILGSRFG-CFEPKRRMRTRGW
MAV_3863|M.avium_104                NYFQSLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKRQMATRGW
MAB_0987c|M.abscessus_ATCC_199      PYFQTLGVPAALGVLVTLAAALTLAPAVLVIAGRFG-LMEPKRAMRTRGW
                                     ***::* * ::*  : : .:*:: .::: :   *   ::***    * *

Mflv_4418|M.gilvum_PYR-GCK          RRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANV
Mvan_1936|M.vanbaalenii_PYR-1       RRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANV
MSMEG_3496|M.smegmatis_MC2_155      RKLGAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANT
TH_3260|M.thermoresistible__bu      RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA
MUL_0757|M.ulcerans_Agy99           RKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANE
Rv0450c|M.tuberculosis_H37Rv        RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
MLBr_02378|M.leprae_Br4923          RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ
MMAR_0775|M.marinum_M               RRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNV
Mb1583|M.bovis_AF2122/97            RRIGTAIVRWPGPILAVACAIAVVGLLALPGYKTSYDARYYMPATAPANI
MAV_3863|M.avium_104                RRIGTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPASAPANT
MAB_0987c|M.abscessus_ATCC_199      RRIGTAIVRWPGPILVVSCIATLVGLLALPGYRTTYDGRIYMPSSVPSNV
                                    *::*. :**** *::  :   :::**::****:*.*. : *:*   *:* 

Mflv_4418|M.gilvum_PYR-GCK          GYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVA
Mvan_1936|M.vanbaalenii_PYR-1       GYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVA
MSMEG_3496|M.smegmatis_MC2_155      GYAAADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGIS
TH_3260|M.thermoresistible__bu      GYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGIS
MUL_0757|M.ulcerans_Agy99           GYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGIS
Rv0450c|M.tuberculosis_H37Rv        GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
MLBr_02378|M.leprae_Br4923          GFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGIS
MMAR_0775|M.marinum_M               GYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVA
Mb1583|M.bovis_AF2122/97            GYMAAERHFPQARLNPELLMIETDHDMRNPADMLILDRIAKAVFHLPGIG
MAV_3863|M.avium_104                GYTAAERHFSQARLNPELLMIETDHDMRNPADMINLERVAKAIAHLPGIA
MAB_0987c|M.abscessus_ATCC_199      GYAAAERHFSVARLNPELLMIETDFDMRNPAGMVLLERVAKSVLHARGVA
                                    *: .*::**  **::**:*::*:*.*:**.:.:: ::::*: :    *:.

Mflv_4418|M.gilvum_PYR-GCK          RVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAM
Mvan_1936|M.vanbaalenii_PYR-1       RVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAM
MSMEG_3496|M.smegmatis_MC2_155      RVQAITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEM
TH_3260|M.thermoresistible__bu      RVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEM
MUL_0757|M.ulcerans_Agy99           RVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDI
Rv0450c|M.tuberculosis_H37Rv        RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
MLBr_02378|M.leprae_Br4923          RVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENM
MMAR_0775|M.marinum_M               RVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAM
Mb1583|M.bovis_AF2122/97            LVQAMTRPLGTPIDHSSIPFQISMQSVGQIQNLKYQRDRAADLLKQAEEL
MAV_3863|M.avium_104                QVQSMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDLLKQADNL
MAB_0987c|M.abscessus_ATCC_199      LVQSITRPLGTPITHSSIPFQISASSASQLMNLSQQQNQALYLSQQADQM
                                     ** :*** *..: *:::.* :*  .  .  . .  ::    :   .  :

Mflv_4418|M.gilvum_PYR-GCK          QTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFR
Mvan_1936|M.vanbaalenii_PYR-1       QTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVR
MSMEG_3496|M.smegmatis_MC2_155      QKSVDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLR
TH_3260|M.thermoresistible__bu      QLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFR
MUL_0757|M.ulcerans_Agy99           QTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFR
Rv0450c|M.tuberculosis_H37Rv        ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
MLBr_02378|M.leprae_Br4923          AETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWR
MMAR_0775|M.marinum_M               QDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWR
Mb1583|M.bovis_AF2122/97            GKTIEILQRQYALQQELAAATHEQAESFHQTIATVKELRDRIANFDDFFR
MAV_3863|M.avium_104                KDTIGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIANFDDFFR
MAB_0987c|M.abscessus_ATCC_199      TNTIAVLRQQLALQKQSAAITHEQTEGFQQTVAVAQDLRDKIANFDDQFR
                                       :  : .   :       *.              .:*: ::::**  *

Mflv_4418|M.gilvum_PYR-GCK          PVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDE
Mvan_1936|M.vanbaalenii_PYR-1       PVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDA
MSMEG_3496|M.smegmatis_MC2_155      PIRNYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDE
TH_3260|M.thermoresistible__bu      PIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLND
MUL_0757|M.ulcerans_Agy99           PIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDT
Rv0450c|M.tuberculosis_H37Rv        PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
MLBr_02378|M.leprae_Br4923          PIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDL
MMAR_0775|M.marinum_M               PIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDI
Mb1583|M.bovis_AF2122/97            PIRSYFYWEKHCYDIPSCWALRSVFDTIDGIDQLGEQLASVTVTLDKLAA
MAV_3863|M.avium_104                PVRSYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTASLDKLDA
MAB_0987c|M.abscessus_ATCC_199      PIRNYFYWEPHCFDIPFCAALRSVFDALDGIDELVDALQSVTGSLTKLDA
                                    *:*.***** ** .:* * ::**:**::**:: :   :  :   : .:  

Mflv_4418|M.gilvum_PYR-GCK          LMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEA
Mvan_1936|M.vanbaalenii_PYR-1       LMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEA
MSMEG_3496|M.smegmatis_MC2_155      LMPQMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQA
TH_3260|M.thermoresistible__bu      LMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEA
MUL_0757|M.ulcerans_Agy99           LMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEA
Rv0450c|M.tuberculosis_H37Rv        LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
MLBr_02378|M.leprae_Br4923          LMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKA
MMAR_0775|M.marinum_M               LMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKA
Mb1583|M.bovis_AF2122/97            IQPQLVALLPDEIASQQINRELALANYATMSGIYAQTAALIENAAAMGQA
MAV_3863|M.avium_104                GQQKLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDTATALGQA
MAB_0987c|M.abscessus_ATCC_199      LQPKLVDLIPPQIAIQEKNRDLTLSNYAINNGTNTQNEESTRTATELGKA
                                       ::   :*  :   .      *       .   *          :*:*

Mflv_4418|M.gilvum_PYR-GCK          FDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATV
Mvan_1936|M.vanbaalenii_PYR-1       FDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATV
MSMEG_3496|M.smegmatis_MC2_155      FDASKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSP
TH_3260|M.thermoresistible__bu      FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP
MUL_0757|M.ulcerans_Agy99           FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ
Rv0450c|M.tuberculosis_H37Rv        FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
MLBr_02378|M.leprae_Br4923          FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV
MMAR_0775|M.marinum_M               FDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPAST
Mb1583|M.bovis_AF2122/97            FDAAKNDDSFYLPPEAFDNPDFQRGLKLFLSADGKAARMIISHEGDPATP
MAV_3863|M.avium_104                YDAAKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISHEGDPATP
MAB_0987c|M.abscessus_ATCC_199      FDDAKNDDSFYLPPEAFDNPAFKRGMKLFMSPDGKAARMIITHQGDPQTS
                                    :* : ******:***.* *  *:*.:: *:*.**::.*:** *.*** : 

Mflv_4418|M.gilvum_PYR-GCK          EGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIA
Mvan_1936|M.vanbaalenii_PYR-1       EGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIA
MSMEG_3496|M.smegmatis_MC2_155      EGIKHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIA
TH_3260|M.thermoresistible__bu      EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA
MUL_0757|M.ulcerans_Agy99           AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA
Rv0450c|M.tuberculosis_H37Rv        EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
MLBr_02378|M.leprae_Br4923          AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA
MMAR_0775|M.marinum_M               EGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIA
Mb1583|M.bovis_AF2122/97            EGISHIDAIKQAAHEAVKGTPMAGAGIYLAGTAATFKDIQDGATYDLLIA
MAV_3863|M.avium_104                EGISHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIA
MAB_0987c|M.abscessus_ATCC_199      EGIAHIDAIKEAAFDAVKATPLADAKIYVAGTASAYKDIADGQKYDLLMA
                                     *:  :  *   * :::* **: .: :*:.**.: ::*: :*  :**::*

Mflv_4418|M.gilvum_PYR-GCK          GIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL
Mvan_1936|M.vanbaalenii_PYR-1       GIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL
MSMEG_3496|M.smegmatis_MC2_155      GIAALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGL
TH_3260|M.thermoresistible__bu      AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL
MUL_0757|M.ulcerans_Agy99           GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI
Rv0450c|M.tuberculosis_H37Rv        AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
MLBr_02378|M.leprae_Br4923          GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI
MMAR_0775|M.marinum_M               GVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGV
Mb1583|M.bovis_AF2122/97            GIAALSLILLIMMIITRSLVAALVIVGTVALSLGASFGLSVLVWQHLLGI
MAV_3863|M.avium_104                GIAALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGI
MAB_0987c|M.abscessus_ATCC_199      ALASLGLILLIMMFLTRSLVAALVIVGTVALSLAASFGMSVVVWQYIFGI
                                    .:::: **::**:.:**:.:*: ****** :**.****:**::** :..:

Mflv_4418|M.gilvum_PYR-GCK          ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGS
Mvan_1936|M.vanbaalenii_PYR-1       ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGS
MSMEG_3496|M.smegmatis_MC2_155      ELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGS
TH_3260|M.thermoresistible__bu      EMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGS
MUL_0757|M.ulcerans_Agy99           ELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGS
Rv0450c|M.tuberculosis_H37Rv        HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
MLBr_02378|M.leprae_Br4923          ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGK
MMAR_0775|M.marinum_M               ELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGG
Mb1583|M.bovis_AF2122/97            QLYWIVLALAVILLLAVGSDYNLLLISRFKEEIGAGLNTGIIRAMAGTGG
MAV_3863|M.avium_104                KLYWICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGSGA
MAB_0987c|M.abscessus_ATCC_199      PLYWVIFPLAVIILLAVGADYNLLLISRFKEETGAGLKTGIIRAIAGTGG
                                     :::: :.:::*:*****:*****:::*:::*  .*::**:**::.*:* 

Mflv_4418|M.gilvum_PYR-GCK          VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV
Mvan_1936|M.vanbaalenii_PYR-1       VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV
MSMEG_3496|M.smegmatis_MC2_155      VVTSAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSI
TH_3260|M.thermoresistible__bu      VVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSI
MUL_0757|M.ulcerans_Agy99           VVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSI
Rv0450c|M.tuberculosis_H37Rv        VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
MLBr_02378|M.leprae_Br4923          VVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSI
MMAR_0775|M.marinum_M               VVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
Mb1583|M.bovis_AF2122/97            VVTAAGLVFAATMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRAFMTPSI
MAV_3863|M.avium_104                VVTSAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVRSFMTPSV
MAB_0987c|M.abscessus_ATCC_199      VVTAAGLVFAVTMSSFVFSDLRVLGQIGTTIGLGLLFDTLVVRSFLTPAI
                                    *** *****. **  :  :.* *:.*:****.:******:::*:*: *::

Mflv_4418|M.gilvum_PYR-GCK          AALLGRWFWWPQKFRSAASERRLARIGVQPATAGR---------------
Mvan_1936|M.vanbaalenii_PYR-1       AALLGRWFWWPQKVRSHASQRRLAALNH----------------------
MSMEG_3496|M.smegmatis_MC2_155      AALMGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV------------
TH_3260|M.thermoresistible__bu      ATLLGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDRVSV----------
MUL_0757|M.ulcerans_Agy99           AALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-------------
Rv0450c|M.tuberculosis_H37Rv        AALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-------
MLBr_02378|M.leprae_Br4923          AALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD-----------
MMAR_0775|M.marinum_M               AALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPEDT
Mb1583|M.bovis_AF2122/97            AVLLGRWFWWPQRVRPRPASRMLRPYGPRPVVRELLLREGND---DPRTQ
MAV_3863|M.avium_104                AALLGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDPAVAPETP
MAB_0987c|M.abscessus_ATCC_199      ATMLGRWFWWPINIRTRPAP---KPFGPKPTG--------ADDTTGPIPV
                                    *.::*:*****   *  .                                

Mflv_4418|M.gilvum_PYR-GCK          ------------
Mvan_1936|M.vanbaalenii_PYR-1       ------------
MSMEG_3496|M.smegmatis_MC2_155      ------------
TH_3260|M.thermoresistible__bu      ------------
MUL_0757|M.ulcerans_Agy99           ------------
Rv0450c|M.tuberculosis_H37Rv        ------------
MLBr_02378|M.leprae_Br4923          ------------
MMAR_0775|M.marinum_M               NTERLAVSSPHY
Mb1583|M.bovis_AF2122/97            VATHR-------
MAV_3863|M.avium_104                SAARHSRG----
MAB_0987c|M.abscessus_ATCC_199      SG----------