For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSGSHAGRSAAEPTFLAKWIRRLSIPIVIGWLAIVFALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHM GKMFKESDSDSVVMIVLEGQERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQSTDGKATY VQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLTVYVTGPGALQTDMNHAGDGSLQLITG LTFLVIVVMLLFFYRSIFTVIMVFMLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAI FLIGRYQEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQTLGVPCSVGLLVGVLV SLTLGPALITIGSRFGLFEPKRAMRIRSWRKIGTTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKY IPKDIPANAGFQAADRHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQAITRPQGT PIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENVVIMKRTLANMTTMAGITHSLVGDMHTL QGTIHEMRDSISNFDDWFRPIRNYLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTL MPKMVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAAKNDDSFYLPPEIFDNAD FKRGMKSFLSPDGKAVRMIISHRGDPATPEGLSHVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSD GAKYDLMIAGISALCLIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHWLVMQMAI IVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTSAGLVFAFTMAVMVVSDLRIIGQVGTTI ALGLLFDTLIVRSFMTPAVATLLGRWFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFP RPSV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2301 | - | - | 100% (984) | putative membrane protein, mmpL |
| M. abscessus ATCC 19977 | MAB_1134c | - | 0.0 | 79.15% (983) | membrane protein MmpL |
| M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 59.47% (940) | MmpL family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 62.64% (953) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_2705 | - | 0.0 | 63.45% (952) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 62.75% (953) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 62.55% (956) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 63.10% (954) | transmembrane transport protein MmpL5_2 |
| M. avium 104 | MAV_2510 | - | 0.0 | 62.57% (943) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 63.78% (947) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 61.08% (943) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 62.84% (950) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 65.09% (951) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2510|M.avium_104 MST-----TFDDTRTDAIPVV--KEPVREKIPRFIRAFAVPIIIGWIALI
MSMEG_3496|M.smegmatis_MC2_155 MSN-----PSHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPIILVWVAII
MUL_0757|M.ulcerans_Agy99 MTA-----TTTDTPTDVVPPA--EHPPRPFIPRMIRTFAVPLILGWVLLI
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGP-SFISTWIRRLSLPIIVGWIALI
Mb0458c|M.bovis_AF2122/97 MSTK----FANDSNTN-------ARPEKPFIARMIHAFAVPIILGWLAVC
Rv0450c|M.tuberculosis_H37Rv MSTK----FANDSNTN-------ARPEKPFIARMIHAFAVPIILGWLAVC
MMAR_0771|M.marinum_M MTVK----YANDPDTR-------THTEKPFLARMIHAFAVPIILAWVAVC
MLBr_02378|M.leprae_Br4923 MTVK----CANDLDTH-------TKP--PFVARMIHRFAVPIILVWLAIA
Mflv_2705|M.gilvum_PYR-GCK MSSS----RDRAALREP-----------RSVARWIRRLAVPIILGWLLLA
Mvan_3833|M.vanbaalenii_PYR-1 MRAH----ADR-DLRDP-----------TPVARWIRRLAIPIILGWVLLV
MAB_2301|M.abscessus_ATCC_1997 MSGS----HAGRSAAEP-----------TFLAKWIRRLSIPIVIGWLAIV
* :. *: :::*::: *: :
MAV_2510|M.avium_104 AVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMI
MSMEG_3496|M.smegmatis_MC2_155 AVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVMI
MUL_0757|M.ulcerans_Agy99 AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI
TH_3260|M.thermoresistible__bu ALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMI
Mb0458c|M.bovis_AF2122/97 VVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMV
Rv0450c|M.tuberculosis_H37Rv VVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMV
MMAR_0771|M.marinum_M VALSVFIPSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMI
MLBr_02378|M.leprae_Br4923 VTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMI
Mflv_2705|M.gilvum_PYR-GCK VALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALI
Mvan_3833|M.vanbaalenii_PYR-1 AALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMV
MAB_2301|M.abscessus_ATCC_1997 FALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMI
:. :*.*: *. .:*.::*. * : : :* * * .*:* ::
MAV_2510|M.avium_104 VLEGQ--QPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQS
MSMEG_3496|M.smegmatis_MC2_155 VLEGE--QPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQS
MUL_0757|M.ulcerans_Agy99 VLEGQ--EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQS
TH_3260|M.thermoresistible__bu VLEGE--EPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQS
Mb0458c|M.bovis_AF2122/97 IIEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
Rv0450c|M.tuberculosis_H37Rv IIEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
MMAR_0771|M.marinum_M VLEGK--DALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQS
MLBr_02378|M.leprae_Br4923 VLEGD--KPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQS
Mflv_2705|M.gilvum_PYR-GCK VLESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQS
Mvan_3833|M.vanbaalenii_PYR-1 VLEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQS
MAB_2301|M.abscessus_ATCC_1997 VLEGQ--ERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQS
::*.. . ** :: :** :: * * :*. :** *.**** ...**
MAV_2510|M.avium_104 NDGKASYVQVYLAGNQGEALANESVESVQNIVKSV---------QAPNGV
MSMEG_3496|M.smegmatis_MC2_155 PDGLASYVQVYTRGNQGEALANESVEAVQDIVESV---------PAPPGV
MUL_0757|M.ulcerans_Agy99 GDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---------QAPPGV
TH_3260|M.thermoresistible__bu PDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGV
Mb0458c|M.bovis_AF2122/97 NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGI
Rv0450c|M.tuberculosis_H37Rv NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGI
MMAR_0771|M.marinum_M NDGKAAYVQLNLAGNQGEPLANESVEAVRKIVKET---------PAPPGV
MLBr_02378|M.leprae_Br4923 NDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---------PAPPGI
Mflv_2705|M.gilvum_PYR-GCK SDGRAAYATLNLAGNMGETESNEAVAAVRDIVANSPP---------PPGV
Mvan_3833|M.vanbaalenii_PYR-1 TDGHAAYVALNLAGNMGETKSNESVAAVRDIVADSPP---------PPGV
MAB_2301|M.abscessus_ATCC_1997 TDGKATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGL
** ::*. : ** * ::*: :.: :: * *:
MAV_2510|M.avium_104 KAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLT
MSMEG_3496|M.smegmatis_MC2_155 KAYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILT
MUL_0757|M.ulcerans_Agy99 KVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIM
TH_3260|M.thermoresistible__bu QAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIA
Mb0458c|M.bovis_AF2122/97 KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
Rv0450c|M.tuberculosis_H37Rv KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
MMAR_0771|M.marinum_M TTYVTGAAALVSDMHSSGDKSMIKITVTTVAVIFIMLLLVYRSVITVVVL
MLBr_02378|M.leprae_Br4923 TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL
Mflv_2705|M.gilvum_PYR-GCK TVHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLL
Mvan_3833|M.vanbaalenii_PYR-1 QVHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTVVLL
MAB_2301|M.abscessus_ATCC_1997 TVYVTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMV
. *** .*: :* : :.: *: : :. ** **:.***. *. :
MAV_2510|M.avium_104 LVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLI
MSMEG_3496|M.smegmatis_MC2_155 LVMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLI
MUL_0757|M.ulcerans_Agy99 LTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLI
TH_3260|M.thermoresistible__bu LFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLI
Mb0458c|M.bovis_AF2122/97 LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
Rv0450c|M.tuberculosis_H37Rv LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
MMAR_0771|M.marinum_M LLTVGVELTAARGVVALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIF
MLBr_02378|M.leprae_Br4923 LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT
Mflv_2705|M.gilvum_PYR-GCK LVVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLV
Mvan_3833|M.vanbaalenii_PYR-1 LIMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLV
MAB_2301|M.abscessus_ATCC_1997 FMLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLI
: * : .:** :* *. ***:.:*..** *::* ..**.**:
MAV_2510|M.avium_104 GRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYF
MSMEG_3496|M.smegmatis_MC2_155 GRYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYF
MUL_0757|M.ulcerans_Agy99 GRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYF
TH_3260|M.thermoresistible__bu GRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYF
Mb0458c|M.bovis_AF2122/97 GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYF
Rv0450c|M.tuberculosis_H37Rv GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYF
MMAR_0771|M.marinum_M GRYQEARQAGEDKETAFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYF
MLBr_02378|M.leprae_Br4923 GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF
Mflv_2705|M.gilvum_PYR-GCK GRYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYF
Mvan_3833|M.vanbaalenii_PYR-1 GRYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYF
MAB_2301|M.abscessus_ATCC_1997 GRYQEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYF
******* . . ::: *: .* **: .**:**:** ** *:.:***
MAV_2510|M.avium_104 QTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKV
MSMEG_3496|M.smegmatis_MC2_155 QSLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKL
MUL_0757|M.ulcerans_Agy99 QTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKI
TH_3260|M.thermoresistible__bu QSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKV
Mb0458c|M.bovis_AF2122/97 QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
Rv0450c|M.tuberculosis_H37Rv QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
MMAR_0771|M.marinum_M ETLGIPCAVGMLVAVMVALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRV
MLBr_02378|M.leprae_Br4923 QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRI
Mflv_2705|M.gilvum_PYR-GCK QSMGIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRI
Mvan_3833|M.vanbaalenii_PYR-1 QSMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRV
MAB_2301|M.abscessus_ATCC_1997 QTLGVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKI
:::* * ::*: : .:**:*.*:: : :** ::*:* : * **::
MAV_2510|M.avium_104 GTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYA
MSMEG_3496|M.smegmatis_MC2_155 GAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYA
MUL_0757|M.ulcerans_Agy99 GAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYS
TH_3260|M.thermoresistible__bu GASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYE
Mb0458c|M.bovis_AF2122/97 GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
Rv0450c|M.tuberculosis_H37Rv GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
MMAR_0771|M.marinum_M GTVVVRWPLPVLAATLAVALVGLLALPGYRTNYNDRDYLPNFIPANQGFT
MLBr_02378|M.leprae_Br4923 GTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFA
Mflv_2705|M.gilvum_PYR-GCK GTMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPANAGLQ
Mvan_3833|M.vanbaalenii_PYR-1 GATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGLQ
MAB_2301|M.abscessus_ATCC_1997 GTTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQ
*: :**** *:: : .::::** :****:*.*.* *:* :*:* *
MAV_2510|M.avium_104 AADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQ
MSMEG_3496|M.smegmatis_MC2_155 AADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQ
MUL_0757|M.ulcerans_Agy99 AAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQ
TH_3260|M.thermoresistible__bu AAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQ
Mb0458c|M.bovis_AF2122/97 AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ
Rv0450c|M.tuberculosis_H37Rv AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ
MMAR_0771|M.marinum_M AAERHFSQARMKPDILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQ
MLBr_02378|M.leprae_Br4923 AADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQ
Mflv_2705|M.gilvum_PYR-GCK AATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQ
Mvan_3833|M.vanbaalenii_PYR-1 AATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQ
MAB_2301|M.abscessus_ATCC_1997 AADRHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQ
** ::* :*:.*::*::::*:*:**.:***:::::*: :* * *:.***
MAV_2510|M.avium_104 AITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTT
MSMEG_3496|M.smegmatis_MC2_155 AITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKS
MUL_0757|M.ulcerans_Agy99 AITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTN
TH_3260|M.thermoresistible__bu GITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLM
Mb0458c|M.bovis_AF2122/97 AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT
Rv0450c|M.tuberculosis_H37Rv AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT
MMAR_0771|M.marinum_M AITRPDGTAMDHTSIPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKT
MLBr_02378|M.leprae_Br4923 AITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAET
Mflv_2705|M.gilvum_PYR-GCK APSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKT
Mvan_3833|M.vanbaalenii_PYR-1 APSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGET
MAB_2301|M.abscessus_ATCC_1997 AITRPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGEN
. :**:* .: ::**** ** ... * . : :* .: .: :
MAV_2510|M.avium_104 IDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMR
MSMEG_3496|M.smegmatis_MC2_155 VDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIR
MUL_0757|M.ulcerans_Agy99 IDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIR
TH_3260|M.thermoresistible__bu IDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIR
Mb0458c|M.bovis_AF2122/97 IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR
Rv0450c|M.tuberculosis_H37Rv IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR
MMAR_0771|M.marinum_M IALMRRMYGLMTQLANNTHKMVGDTIEMQQITKELRDHIANFDDFFRPIR
MLBr_02378|M.leprae_Br4923 IASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIR
Mflv_2705|M.gilvum_PYR-GCK LGTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVR
Mvan_3833|M.vanbaalenii_PYR-1 IATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIR
MAB_2301|M.abscessus_ATCC_1997 VVIMKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIR
: : : :: . : .:*: :: *:* **:*
MAV_2510|M.avium_104 SYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMP
MSMEG_3496|M.smegmatis_MC2_155 NYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMP
MUL_0757|M.ulcerans_Agy99 SYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMP
TH_3260|M.thermoresistible__bu NYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMP
Mb0458c|M.bovis_AF2122/97 SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP
Rv0450c|M.tuberculosis_H37Rv SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP
MMAR_0771|M.marinum_M SYFYWEKHCYDIPICSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMP
MLBr_02378|M.leprae_Br4923 SYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMP
Mflv_2705|M.gilvum_PYR-GCK NYFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLP
Mvan_3833|M.vanbaalenii_PYR-1 NYFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLP
MAB_2301|M.abscessus_ATCC_1997 NYLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMP
.*:*** ** .**:* ::**:**::* :. : : : : : : *:*
MAV_2510|M.avium_104 QMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDA
MSMEG_3496|M.smegmatis_MC2_155 QMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDA
MUL_0757|M.ulcerans_Agy99 QMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDS
TH_3260|M.thermoresistible__bu QMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQ
Mb0458c|M.bovis_AF2122/97 QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA
Rv0450c|M.tuberculosis_H37Rv QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA
MMAR_0771|M.marinum_M QMIETFPPMIETMESMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDA
MLBr_02378|M.leprae_Br4923 QMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDT
Mflv_2705|M.gilvum_PYR-GCK QMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDE
Mvan_3833|M.vanbaalenii_PYR-1 QMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDA
MAB_2301|M.abscessus_ATCC_1997 KMVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDA
:* :. : *: *: :*: :* *: :* : . **:***
MAV_2510|M.avium_104 SKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGI
MSMEG_3496|M.smegmatis_MC2_155 SKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGI
MUL_0757|M.ulcerans_Agy99 SRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGI
TH_3260|M.thermoresistible__bu ARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGL
Mb0458c|M.bovis_AF2122/97 AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI
Rv0450c|M.tuberculosis_H37Rv AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI
MMAR_0771|M.marinum_M AKNDDSFYLPPEVFKNEDFKRAMKSFLSPDGHAARFIILHRGDPQSAQGI
MLBr_02378|M.leprae_Br4923 AKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGI
Mflv_2705|M.gilvum_PYR-GCK AKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEAL
Mvan_3833|M.vanbaalenii_PYR-1 AKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEAL
MAB_2301|M.abscessus_ATCC_1997 AKNDDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGL
::********** *.* :*::.:: *:*.**::.*::: * *:* : .:
MAV_2510|M.avium_104 SHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGIS
MSMEG_3496|M.smegmatis_MC2_155 KHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIA
MUL_0757|M.ulcerans_Agy99 NHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGIS
TH_3260|M.thermoresistible__bu AKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIA
Mb0458c|M.bovis_AF2122/97 KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS
Rv0450c|M.tuberculosis_H37Rv KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS
MMAR_0771|M.marinum_M ASIDQIRTAAEESLKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAGIS
MLBr_02378|M.leprae_Br4923 ASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGIS
Mflv_2705|M.gilvum_PYR-GCK ARVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILS
Mvan_3833|M.vanbaalenii_PYR-1 QRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVIS
MAB_2301|M.abscessus_ATCC_1997 SHVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGIS
: *: ** *::******.: : :.**.: ::*:.:* :*::** ::
MAV_2510|M.avium_104 SLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELH
MSMEG_3496|M.smegmatis_MC2_155 ALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELH
MUL_0757|M.ulcerans_Agy99 ALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELH
TH_3260|M.thermoresistible__bu AVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMH
Mb0458c|M.bovis_AF2122/97 SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH
Rv0450c|M.tuberculosis_H37Rv SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH
MMAR_0771|M.marinum_M SLCLIFIIMLILTRAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLH
MLBr_02378|M.leprae_Br4923 SLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELH
Mflv_2705|M.gilvum_PYR-GCK ALCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELH
Mvan_3833|M.vanbaalenii_PYR-1 ALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELH
MAB_2301|M.abscessus_ATCC_1997 ALCLIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELH
::**:::***::**..:*: ****** :**.****:*:::**::: :.:*
MAV_2510|M.avium_104 WMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVT
MSMEG_3496|M.smegmatis_MC2_155 WMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVT
MUL_0757|M.ulcerans_Agy99 WLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVT
TH_3260|M.thermoresistible__bu WMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVT
Mb0458c|M.bovis_AF2122/97 WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT
Rv0450c|M.tuberculosis_H37Rv WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT
MMAR_0771|M.marinum_M YMVLAMSVIVLLAVGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVT
MLBr_02378|M.leprae_Br4923 YLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVT
Mflv_2705|M.gilvum_PYR-GCK WMVLVMSIIALIAVGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVS
Mvan_3833|M.vanbaalenii_PYR-1 WMVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVT
MAB_2301|M.abscessus_ATCC_1997 WLVMQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVT
::*: :::* *:***:*****:*:*:::*: .*::**:**::**:*.**:
MAV_2510|M.avium_104 SAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAAL
MSMEG_3496|M.smegmatis_MC2_155 SAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAAL
MUL_0757|M.ulcerans_Agy99 AAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAAL
TH_3260|M.thermoresistible__bu AAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATL
Mb0458c|M.bovis_AF2122/97 NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL
Rv0450c|M.tuberculosis_H37Rv NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL
MMAR_0771|M.marinum_M NAGLVFAFTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAAL
MLBr_02378|M.leprae_Br4923 NAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAAL
Mflv_2705|M.gilvum_PYR-GCK VAGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATL
Mvan_3833|M.vanbaalenii_PYR-1 VAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATL
MAB_2301|M.abscessus_ATCC_1997 SAGLVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATL
**:**..** :.**:* ::.******.:******:::*::* *::*:*
MAV_2510|M.avium_104 LGKWFWWPQRVRQRPVPSPWPKPAAQEREVLADA----------------
MSMEG_3496|M.smegmatis_MC2_155 MGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV---------------
MUL_0757|M.ulcerans_Agy99 LGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV----------------
TH_3260|M.thermoresistible__bu LGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV--------------
Mb0458c|M.bovis_AF2122/97 LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------
Rv0450c|M.tuberculosis_H37Rv LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG----------
MMAR_0771|M.marinum_M LGRWFWWPMRVRTRPARTPSSPTADPEPDRALAMSGER------------
MLBr_02378|M.leprae_Br4923 LGRWFWWPQQGRTRPLLTVAAPVG-LPPDRSLVYSD--------------
Mflv_2705|M.gilvum_PYR-GCK LGRWFWWPLVVRSRPLRPR-------PQQQALGVGGQQG-----------
Mvan_3833|M.vanbaalenii_PYR-1 LGRWFWWPLVVRSRPLRLP-------PRT---------------------
MAB_2301|M.abscessus_ATCC_1997 LGRWFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRP
:*:***** * **
MAV_2510|M.avium_104 --
MSMEG_3496|M.smegmatis_MC2_155 --
MUL_0757|M.ulcerans_Agy99 --
TH_3260|M.thermoresistible__bu --
Mb0458c|M.bovis_AF2122/97 --
Rv0450c|M.tuberculosis_H37Rv --
MMAR_0771|M.marinum_M --
MLBr_02378|M.leprae_Br4923 --
Mflv_2705|M.gilvum_PYR-GCK --
Mvan_3833|M.vanbaalenii_PYR-1 --
MAB_2301|M.abscessus_ATCC_1997 SV