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VTGFLSGTAFADRTVVLIGGGTGIGLSVARLVTAAGGDVVLGGRTPATLAVAAEELGGKARWHLVDTAHQ ASIDAFFDQIEVLHGLFTTAATYVTGSIAALSVEQAATPFESKFWGQYRVVKSALPKLSSDASVVLMSGA ASVRPAGSAPAYVAANAAIEGLARGLAHELAPIRVNALSPGTVDGHLWNQRPPEIRRQAFEHIAAAATLR RPVTEGEVAQAAVYLLLNSATTGSTLYTDGGYALR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0057 | - | - | 100% (245) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0164 | - | 7e-19 | 29.92% (254) | short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0259c | - | 2e-18 | 31.32% (265) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 8e-16 | 28.85% (253) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4353 | - | 5e-16 | 29.41% (255) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0927c | - | 8e-16 | 28.85% (253) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-10 | 25.61% (246) | 3-oxoacyl- |
| M. marinum M | MMAR_0587 | - | 1e-19 | 30.25% (238) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2726 | - | 5e-17 | 30.33% (244) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1563 | - | 2e-26 | 32.92% (240) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2589 | - | 5e-20 | 33.06% (242) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1037 | fabG3 | 2e-15 | 27.39% (241) | 20-beta-hydroxysteroid dehydrogenase FabG3 |
| M. vanbaalenii PYR-1 | Mvan_1212 | - | 9e-21 | 31.82% (242) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0587|M.marinum_M --------------------------MGQLEGKTALVTGGNSGIGLAAAQ
MAV_2726|M.avium_104 --------------------------MGLLDRKTAVITGANSGIGLATAE
Mvan_1212|M.vanbaalenii_PYR-1 ---------------------------MELTGQTALITGGTAGIGLACAQ
Mb0950c|M.bovis_AF2122/97 ----------------------MILDMFRLDDKVAVITGGGRGLGAAIAL
Rv0927c|M.tuberculosis_H37Rv ----------------------MILDMFRLDDKVAVITGGGRGLGAAIAL
MLBr_01807|M.leprae_Br4923 --------------------------MTDAAAKVSAAPGRGKPAFVSRSI
MUL_1037|M.ulcerans_Agy99 --------------------------MGRVDGKVALISGGARGMGASHAR
TH_2589|M.thermoresistible__bu ------------------VDRQTFDKLFDMTGRTVVVTGGTRGIGLALAE
MAB_0057|M.abscessus_ATCC_1997 --------------------MTGFLSGTAFADRTVVLIGGGTGIGLSVAR
MSMEG_1563|M.smegmatis_MC2_155 MGPYRQGIAERRKESWTSPDTATDSGGMNLKNARVLLVGGTSGIGLGVAT
Mflv_4353|M.gilvum_PYR-GCK -------------------------MDLGLRDATVVVVGGGRGMGLAAAH
* . :
MMAR_0587|M.marinum_M RLAAEGAH-------VFLTGRNQATIDAAVASIG----SRAHGIRADVSN
MAV_2726|M.avium_104 RFLAEGVER------VFITGRRQRELEDAARQLG----PRATAVRGDVGA
Mvan_1212|M.vanbaalenii_PYR-1 LMAREGAD-------VVITGRDPGRGEAAAASD-----PRLRFLRCDLAD
Mb0950c|M.bovis_AF2122/97 AFAQAGAD-------VLIASRTSSELDAVAEQIRAAG-RRAHTVAADLAH
Rv0927c|M.tuberculosis_H37Rv AFAQAGAD-------VLIASRTSSELDAVAEQIRAAG-RRAHTVAADLAH
MLBr_01807|M.leprae_Br4923 LVTGGNRGIGLAVARRLVADGHRVAVTHRASVVP----DWFFGVECDVTD
MUL_1037|M.ulcerans_Agy99 LLVQEG-------AKVVIGDILDEEGKALAEEIG----DAARYVHLDVTQ
TH_2589|M.thermoresistible__bu GYVLAGAR-------VVVASRKSDACERAAAHLRALG-GDAIGVPTHLGD
MAB_0057|M.abscessus_ATCC_1997 LVTAAGGD-------VVLGGRTPATLAVAAEELG-------GKARWHLVD
MSMEG_1563|M.smegmatis_MC2_155 AVAERGGV-------PIVASRNQASVDRALGTLP-------DGARGLTVD
Mflv_4353|M.gilvum_PYR-GCK CFADDGAR-------VALVGRTRDVLDEAAAQLRGRGSPDAVGVVADCAD
. : .
MMAR_0587|M.marinum_M IEDLARVADAIAAAG-RGLDVLFANAGGGEFVLLGDITIEHFTNGFMTNV
MAV_2726|M.avium_104 PRDLDRLYGEVAAAG-AGLDIVMANAGTTRVARLGEITDDDLDTLLGTNV
Mvan_1212|M.vanbaalenii_PYR-1 RTSIESLVQQAPP-----VDILVNNAASFPGAMTVDQDAATFQRTFDTNV
Mb0950c|M.bovis_AF2122/97 PEVTAQLAGQAVGAF-GKLDIVVNNVGGTMPNTLLSTSTKDLADAFAFNV
Rv0927c|M.tuberculosis_H37Rv PEVTAQLAGQAVGAF-GKLDIVVNNVGGTMPNTLLSTSTKDLADAFAFNV
MLBr_01807|M.leprae_Br4923 NDAIGAAFKAVEEHQ-GPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNL
MUL_1037|M.ulcerans_Agy99 PDQWEAAVATAVDEF-GKLDVLVNNVGIVALGQLKKFDLGKWQKVIDVNL
TH_2589|M.thermoresistible__bu IDACEALVRRTVDEF-GGIDVLVNNAANALTQPLGELTVDAWTKSFEVNL
MAB_0057|M.abscessus_ATCC_1997 TAHQASIDAFFDQI--EVLHGLFTTAATYVTGSIAALSVEQAATPFESKF
MSMEG_1563|M.smegmatis_MC2_155 LTDPAALAGFAAQVG-PIEHLVFTAGEELQMYPLADITAEAIGDLFGTRF
Mflv_4353|M.gilvum_PYR-GCK EAAVQRAFGELAERWNGELNVLVNAVGPTVRGTFDELSDADWRQAVDEGA
. :. .
MMAR_0587|M.marinum_M AGTLFTVQTMLP--LLNSGA-SIVLTGSTAAYNGSPAFSVYAATKAAIRS
MAV_2726|M.avium_104 KGVVYTVQKALP--LLNDGA-SIILTGSTTADRGRAGLSIYAATKAAVRS
Mvan_1212|M.vanbaalenii_PYR-1 GGTYFLTAAVVPAMLLRGRG-AIVNVTSMVAWKGVPGASVYSASKAAVES
Mb0950c|M.bovis_AF2122/97 GTAHALTVAAVPLMLEHSGGGSVINISSTMGRLAARGFAAYGTAKAALAH
Rv0927c|M.tuberculosis_H37Rv GTAHALTVAAVPLMLEHSGGGSVINISSTMGRLAARGFAAYGTAKAALAH
MLBr_01807|M.leprae_Br4923 TGVFRVAKLASRNMIKQRFG-RYIFMGSVVGLSGVPGQANYAASKSGLIG
MUL_1037|M.ulcerans_Agy99 TGTFLGMRAAVEPMTAAGSG-SIINVSSIEGLRGAPAVHPYVASKWAVRG
TH_2589|M.thermoresistible__bu RGPVFLVQAALPHLKTSPHA-AVLNMVSVGAFLFSPGTAMYSAGKAALMS
MAB_0057|M.abscessus_ATCC_1997 WGQYRVVKSALP--KLSSDASVVLMSGAASVRP-AGSAPAYVAANAAIEG
MSMEG_1563|M.smegmatis_MC2_155 AGQLLSVRAFAP--RITAGGSITLTSGTAADKPDLGVLPAAVCG--AVSA
Mflv_4353|M.gilvum_PYR-GCK MGMVRCVRAALPLLRAAEWA-RIVNFSAHSTQRQSVILPAYTAAKAMVTS
. : : :
MMAR_0587|M.marinum_M FGRTWAAELVSRNIRVNTVVPGPVETPGLKGLAPEGQ---------EQQL
MAV_2726|M.avium_104 LARAWANELAHRNIRVNVLVAGSTATPGSDRLAAQTDP-----YVSVEEF
Mvan_1212|M.vanbaalenii_PYR-1 LTRTWAAEFAP-HVRVNSVAPGPTDTEGVVAEWGDTN----------DEL
Mb0950c|M.bovis_AF2122/97 YTRLAALDLCP-RVRVNAIAPGSILTSALEVVAANDE------------L
Rv0927c|M.tuberculosis_H37Rv YTRLAALDLCP-RVRVNAIAPGSILTSALEVVAANDE------------L
MLBr_01807|M.leprae_Br4923 MARSLARELGSRSITANVVAPGFIDTEMTRAMDSKYQ-------------
MUL_1037|M.ulcerans_Agy99 LTKSAALELAPLNIRVNSIHPGFIRTPMTANLP-----------------
TH_2589|M.thermoresistible__bu FTRSMAAQFAPLGIRVNALAPGPVDTDMMRNNPQEVV-------------
MAB_0057|M.abscessus_ATCC_1997 LARGLAHELAP--IRVNALSPGTVDGHLWNQRPPEIR----------RQA
MSMEG_1563|M.smegmatis_MC2_155 MTRALAVELAP--LRVNAVAPGPIDTPLWSALAPEGR----------DAL
Mflv_4353|M.gilvum_PYR-GCK ISKNLSLLLARDEILVNVVSPGSIASEALVGWADSVGVDGSDPYALMAAI
: : : : .* : .*
MMAR_0587|M.marinum_M LEGEAAKVPMGRLGKPAEIAAAVLFLASDQSSFMTGSEMFVDGGTEQL--
MAV_2726|M.avium_104 RAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCTGSTVTADGGFNQV--
Mvan_1212|M.vanbaalenii_PYR-1 GR----ALPLGRTATPGEIAQAVLFLASPRAGFVTGSVLHADGGGTAI--
Mb0950c|M.bovis_AF2122/97 RAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNL
Rv0927c|M.tuberculosis_H37Rv RAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNL
MLBr_01807|M.leprae_Br4923 -EAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
MUL_1037|M.ulcerans_Agy99 --DDMVTIPLGRPAESREVSTFVVFLASDDASYATGSEFVMDGGLVTDVP
TH_2589|M.thermoresistible__bu -DMMAGATLMKRLATPDEMVGAALLLTSDAGSYITGTVLIADGGGTPR--
MAB_0057|M.abscessus_ATCC_1997 FEHIAAAATLRRPVTEGEVAQAAVYLLLN--SATTGSTLYTDGGYALR--
MSMEG_1563|M.smegmatis_MC2_155 YAQYAQQLPAGRMGAVTDTALAYTYLMEQ--EFGTGQVLTVDGGGTLV--
Mflv_4353|M.gilvum_PYR-GCK DEHFGHPAHLPRAGLPTEIGSVVAFLASRRNSYMTGADINVDGGSDFT--
* : * :* . ***
MMAR_0587|M.marinum_M -------
MAV_2726|M.avium_104 -------
Mvan_1212|M.vanbaalenii_PYR-1 -------
Mb0950c|M.bovis_AF2122/97 DLPIPDL
Rv0927c|M.tuberculosis_H37Rv DLPIPDL
MLBr_01807|M.leprae_Br4923 -------
MUL_1037|M.ulcerans_Agy99 HKQF---
TH_2589|M.thermoresistible__bu -------
MAB_0057|M.abscessus_ATCC_1997 -------
MSMEG_1563|M.smegmatis_MC2_155 -------
Mflv_4353|M.gilvum_PYR-GCK -------