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VNLTDFQSLYDLSGRTAIVTGGTRGIGYAIAEALGACGASVVVSSRKSDACTAAAKELHDKGYRALGVPA HMGELGDIDALVTATVDEYGGVDIVVNAAANPVAQPMGSYTPEALGKSFDVNVRGPVFLVQAALPHLTAS EHASVLNVVSVAAFQYVPMLSMYAAMKATLMSFTRSMAAEYTARGIRVNALAPGTVDTYMLQQNPQEIID AMAAQSFMGRVAHTDEMIGPALLLLSDAGSFITGQVIVADGGGGVQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0164 | - | - | 100% (257) | short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0833 | - | 3e-80 | 58.33% (252) | Short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0952 | - | 4e-34 | 36.84% (247) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 2e-38 | 37.04% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4818 | - | 7e-87 | 62.50% (248) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 2e-38 | 37.04% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-21 | 29.88% (241) | 3-oxoacyl- |
| M. marinum M | MMAR_1952 | fabG | 6e-37 | 36.63% (243) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 4e-39 | 37.45% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_1740 | - | 1e-84 | 62.10% (248) | dehydrogenase/reductase SDR family protein member 4 |
| M. thermoresistible (build 8) | TH_2589 | - | 2e-83 | 60.47% (253) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 2e-36 | 36.21% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1624 | - | 4e-88 | 63.24% (253) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4818|M.gilvum_PYR-GCK -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGARVVV
Mvan_1624|M.vanbaalenii_PYR-1 -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYVLAGARVVV
MSMEG_1740|M.smegmatis_MC2_155 -------MDRQRFERLFDMSDRTVIVTGGTRGIGLSLAEGFVLAGARVVV
TH_2589|M.thermoresistible__bu -------VDRQTFDKLFDMTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MAB_0164|M.abscessus_ATCC_1997 -------MNLTDFQSLYDLSGRTAIVTGGTRGIGYAIAEALGACGASVVV
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MMAR_1952|M.marinum_M -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MUL_2173|M.ulcerans_Agy99 -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MAV_3655|M.avium_104 -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .*: ::**..**** ::*. * *.:
Mflv_4818|M.gilvum_PYR-GCK ASRKADACEQAAHHLRELGAQAIGVPTHLGQVDDLGALVERTVAEFGGLD
Mvan_1624|M.vanbaalenii_PYR-1 ASRKADACEETARHLRELGGSAIGVPTHLGEVDDLGALVERTVAEFGGVD
MSMEG_1740|M.smegmatis_MC2_155 ASRKPDACETAAAHLRELGGDAVGVPAHTGDVDDLGAVVERAVSEFGGVD
TH_2589|M.thermoresistible__bu ASRKSDACERAAAHLRALGGDAIGVPTHLGDIDACEALVRRTVDEFGGID
MAB_0164|M.abscessus_ATCC_1997 SSRKSDACTAAAKELHDKGYRALGVPAHMGELGDIDALVTATVDEYGGVD
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQVGDR---ALGVGAHAVDEDAARRCVDLTLERFGSVD
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQVGDR---ALGVGAHAVDEDAARRCVDLTLERFGSVD
MMAR_1952|M.marinum_M TARKQESADAAAAEVGER---AVGVGAHAVDEEAARGCVDLALERFGSVD
MUL_2173|M.ulcerans_Agy99 TARKQESADAAAAEVGER---AVGVGAHAVDEEAARGCVDLALERFGSVD
MAV_3655|M.avium_104 TARKQEAADEAAAQVGPQ---ALGVGAHAVDEDAARQCVQLTLERFGSVD
MLBr_01807|M.leprae_Br4923 THRASVVPD-----------WFFGVECDVTDNDAIGAAFKAVEEHQGPVE
: * .** . : . . . * ::
Mflv_4818|M.gilvum_PYR-GCK VLVNNAAN-PLAQPFGHMTVDALSKSFEVNLQGPVMLTQEALPHLKASDH
Mvan_1624|M.vanbaalenii_PYR-1 VLVNNAAN-PLAQPFGYMTVDALTKSFEVNLRGPVMLVQEALPHLKASEH
MSMEG_1740|M.smegmatis_MC2_155 VVVNNAAN-ALAQPLGKMTPEAWAKSYEVNLRGPVFLVQHALPYLQKSQN
TH_2589|M.thermoresistible__bu VLVNNAAN-ALTQPLGELTVDAWTKSFEVNLRGPVFLVQAALPHLKTSPH
MAB_0164|M.abscessus_ATCC_1997 IVVNAAAN-PVAQPMGSYTPEALGKSFDVNVRGPVFLVQAALPHLTASEH
Mb2788c|M.bovis_AF2122/97 ILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHG
Rv2766c|M.tuberculosis_H37Rv ILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHG
MMAR_1952|M.marinum_M ILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEHG
MUL_2173|M.ulcerans_Agy99 ILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEHG
MAV_3655|M.avium_104 ILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEHG
MLBr_01807|M.leprae_Br4923 VLVANAGI-TSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
::: *. . : * :**: . . .. . .
Mflv_4818|M.gilvum_PYR-GCK AAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHDGIRVNALA
Mvan_1624|M.vanbaalenii_PYR-1 AAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHHGIRVNALA
MSMEG_1740|M.smegmatis_MC2_155 AAVLNMVSVGAFNFAPALSIYASSKAALMSVTRSMAAEFAPSGIRVNALA
TH_2589|M.thermoresistible__bu AAVLNMVSVGAFLFSPGTAMYSAGKAALMSFTRSMAAQFAPLGIRVNALA
MAB_0164|M.abscessus_ATCC_1997 ASVLNVVSVAAFQYVPMLSMYAAMKATLMSFTRSMAAEYTARGIRVNALA
Mb2788c|M.bovis_AF2122/97 GAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAIC
Rv2766c|M.tuberculosis_H37Rv GAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAIC
MMAR_1952|M.marinum_M GVVINTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNAIC
MUL_2173|M.ulcerans_Agy99 GVVINTASIGGMHQSPAMGMYNATNAALIHVTKQLALELSPR-VRVNAIC
MAV_3655|M.avium_104 GSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNAIA
MLBr_01807|M.leprae_Br4923 GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
. : *: .: * . * : :: :: .::.:* : : .*.:.
Mflv_4818|M.gilvum_PYR-GCK PGPVDTDMMRKNPQEAIDGMVGGTLVGRLASADEMVGAALLLTSDAGSYI
Mvan_1624|M.vanbaalenii_PYR-1 PGPVDTDMMRKNPQEAIDGMVGGTLLGRLATPDEMVGAALLLTSDAGSYI
MSMEG_1740|M.smegmatis_MC2_155 PGPVDTDMMRKNPQEAIDAMTAGTLMKRLAHPDEMVGAALLLCSDAGSYM
TH_2589|M.thermoresistible__bu PGPVDTDMMRNNPQEVVDMMAGATLMKRLATPDEMVGAALLLTSDAGSYI
MAB_0164|M.abscessus_ATCC_1997 PGTVDTYMLQQNPQEIIDAMAAQSFMGRVAHTDEMIGPALLLLSDAGSFI
Mb2788c|M.bovis_AF2122/97 PGVVRTRLAEALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAASWI
Rv2766c|M.tuberculosis_H37Rv PGVVRTRLAEALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAASWI
MMAR_1952|M.marinum_M PGVVRTKLAEALWKDHEDPLAANIALGRIGEPVDVAEAVGFLVSDAASWI
MUL_2173|M.ulcerans_Agy99 PGVVRTKLAEALWKDHEDPLAANIALGRIGEPVDVAEAVGFLVSDAASWI
MAV_3655|M.avium_104 PGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWI
MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYI
** : * : . .. : : *:. :: .. :* *: ..::
Mflv_4818|M.gilvum_PYR-GCK TGQVIIADGGG-TPR------------
Mvan_1624|M.vanbaalenii_PYR-1 TGQVIIADGGG-TPR------------
MSMEG_1740|M.smegmatis_MC2_155 TGQVVIVDGGG-TPR------------
TH_2589|M.thermoresistible__bu TGTVLIADGGG-TPR------------
MAB_0164|M.abscessus_ATCC_1997 TGQVIVADGGGGVQR------------
Mb2788c|M.bovis_AF2122/97 TGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv TGETMIIDGGLLLGNALGFRAAPSTEH
MMAR_1952|M.marinum_M TGETMVIDGGLLLGSAAGFQSRPGSAS
MUL_2173|M.ulcerans_Agy99 TGETMVIDGGLLLGSAAGFQSRPGSAS
MAV_3655|M.avium_104 TGETLVIDGGTVLGAAQGFRSAPTPS-
MLBr_01807|M.leprae_Br4923 SGAVIPVDGGLGMGH------------
:* .: ***