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GLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGPRATAVRGDVGAPRDLDRL YGEVAAAGAGLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTVQKALPLLNDGASIILTGSTTA DRGRAGLSIYAATKAAVRSLARAWANELAHRNIRVNVLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIA TIPLGRFADPVEIAHAAVFLASDLSSFCTGSTVTADGGFNQV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2726 | - | - | 100% (253) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1242 | - | 5e-55 | 47.84% (255) | short-chain dehydrogenase/reductase SDR |
| M. avium 104 | MAV_1572 | - | 4e-32 | 33.60% (253) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 1e-32 | 34.66% (251) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 2e-31 | 33.20% (253) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1350 | fabG | 1e-32 | 34.66% (251) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-18 | 27.35% (245) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 2e-31 | 36.76% (253) | short chain dehydrogenase |
| M. marinum M | MMAR_0587 | - | 3e-61 | 50.59% (253) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_6823 | - | 4e-56 | 49.41% (253) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3954 | - | 7e-31 | 35.34% (249) | PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase |
| M. ulcerans Agy99 | MUL_3898 | fabG | 2e-30 | 33.20% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 1e-58 | 49.80% (253) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1385|M.bovis_AF2122/97 ------------MASLLNAR--------TAVITGGAQGLGLAIGQRFVAE
Rv1350|M.tuberculosis_H37Rv ------------MASLLNAR--------TAVITGGAQGLGLAIGQRFVAE
MUL_3898|M.ulcerans_Agy99 ------------MCGAHRDRGY-----VYPVVTGGAQGLGLAIAERFVSE
Mflv_4369|M.gilvum_PYR-GCK -------------MSLLTGQ--------TAVITGGAQGLGFAIAQRFVDE
TH_3954|M.thermoresistible__bu ------------MPSALLAEK-------VAVVTGAGRGIGREIARVLHAH
MMAR_0587|M.marinum_M -------------MGQLEGK--------TALVTGGNSGIGLAAAQRLAAE
MSMEG_6823|M.smegmatis_MC2_155 -------------MGQLDGK--------TALVTGGTSGIGHAAAKRLVQE
Mvan_1616|M.vanbaalenii_PYR-1 -------------MGTLEGK--------TAVVTGASSGIGLAAAQRLADE
MAV_2726|M.avium_104 -------------MGLLDRK--------TAVITGANSGIGLATAERFLAE
MAB_0952|M.abscessus_ATCC_1997 MVVESAEPAERKVMFDLSAR--------SVLVTGGTKGIGRGIATVFARA
MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD
. ::**. *:* . :
Mb1385|M.bovis_AF2122/97 GAR-VVLGDVNLEATEVAAKRLGGDDV--ALAVRCDVTQADDVDILIRTA
Rv1350|M.tuberculosis_H37Rv GAR-VVLGDVNLEATEVAAKRLGGDDV--ALAVRCDVTQADDVDILIRTA
MUL_3898|M.ulcerans_Agy99 GAR-VVLGDVNLEATEAAAKQLGGGEV--AVAVRCDVTKADEVETLLQAA
Mflv_4369|M.gilvum_PYR-GCK GAR-VVLGDVNLEATQEAAEKLGGADV--AHAVRCDVTSSAEVDALVAAA
TH_3954|M.thermoresistible__bu GAE-VVLADLDADAAAQAAAEVDG------TGVGCDVTAEDQMKRLVADT
MMAR_0587|M.marinum_M GAH-VFLTGRNQATIDAAVASIGSR----AHGIRADVSNIEDLARVADAI
MSMEG_6823|M.smegmatis_MC2_155 GAY-VFITGRDRTRAEKAAASIG------AHGVQSDVSNPDELDALAAEI
Mvan_1616|M.vanbaalenii_PYR-1 GAH-VFITGRKKPALDAAAASLGSA----ATAVVGDIARAADLDQLYDAV
MAV_2726|M.avium_104 GVERVFITGRRQRELEDAARQLGPR----ATAVRGDVGAPRDLDRLYGEV
MAB_0952|M.abscessus_ATCC_1997 GAN-VAVAARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTV
MLBr_01807|M.leprae_Br4923 GHR-VAVTHRASVVPD------------WFFGVECDVTDNDAIGAAFKAV
* * : .: *:
Mb1385|M.bovis_AF2122/97 VERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAA
Rv1350|M.tuberculosis_H37Rv VERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAA
MUL_3898|M.ulcerans_Agy99 LERFGGLDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAA
Mflv_4369|M.gilvum_PYR-GCK VDTFGALDIMVNNAGITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAA
TH_3954|M.thermoresistible__bu VAKHGRLDLFVNNAGITRDASLKRMTVADFDAVVTVHLRGTWLGVREATA
MMAR_0587|M.marinum_M AAAGRGLDVLFANAGGGEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLP
MSMEG_6823|M.smegmatis_MC2_155 AEYGKGLDVVFANAGGGDYATLAEVTPQHYRDNIDRNVGGTVFTVQKILP
Mvan_1616|M.vanbaalenii_PYR-1 RARGRGLDVLFANAGLAVLGPLAQATEADYEQNFDVNVRGTWLTVQKAAP
MAV_2726|M.avium_104 AAAGAGLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTVQKALP
MAB_0952|M.abscessus_ATCC_1997 VDAFGALDVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLA
MLBr_01807|M.leprae_Br4923 EEHQGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASR
:::. *** : : . . :: *. :
Mb1385|M.bovis_AF2122/97 IMRER-KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHL
Rv1350|M.tuberculosis_H37Rv IMRER-KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHL
MUL_3898|M.ulcerans_Agy99 IMREN-KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHV
Mflv_4369|M.gilvum_PYR-GCK IMREN-KRGVIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYL
TH_3954|M.thermoresistible__bu VMREQ-KSGSIVNISSLSGKSGNPGQTNYSAAKAGIIGLTKAAAKEVAHH
MMAR_0587|M.marinum_M LLNS---GASIVLTGSTAAYNGSPAFSVYAATKAAIRSFGRTWAAELVSR
MSMEG_6823|M.smegmatis_MC2_155 LLND---GASIILTGSTAPAKGTPAFGLYAASKAAIRSLGRTWAAELVDR
Mvan_1616|M.vanbaalenii_PYR-1 LLND---GASVIVNSSIRADDGWENFGLYSASKAAVRSLARTWANELKDR
MAV_2726|M.avium_104 LLND---GASIILTGSTTADRGRAGLSIYAATKAAVRSLARAWANELAHR
MAB_0952|M.abscessus_ATCC_1997 PLTASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPR
MLBr_01807|M.leprae_Br4923 NMIKQ-RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSR
: : . * *.*:*:. .: :: : *:
Mb1385|M.bovis_AF2122/97 GIRVNAIAPGLIRSAMTEAMPQRI---------WDQKLAEVPMGRAGEPS
Rv1350|M.tuberculosis_H37Rv GIRVNAIAPGLIRSAMTEAMPQRI---------WDQKLAEVPMGRAGEPS
MUL_3898|M.ulcerans_Agy99 GVRVNAIAPGLIRSAMTEAMPQRI---------WDQKLAEVPMGRAGEPS
Mflv_4369|M.gilvum_PYR-GCK GVRVNAIQPGLIRSAMTEAMPQRI---------WDSKVAEVPLGRAGEPD
TH_3954|M.thermoresistible__bu NVRVNAIQPGLIRTPMTETMPAEV---------FAEREAAVPMKRAGEPA
MMAR_0587|M.marinum_M NIRVNTVVPGPVETPGLKGLAPEG----QEQQLLEGEAAKVPMGRLGKPA
MSMEG_6823|M.smegmatis_MC2_155 NIRVNTVIPGPIRTPGLEGLAPDG----QRE--LDGWAAQVPMKRLGDPD
Mvan_1616|M.vanbaalenii_PYR-1 GIRVNTVSPGAIDTPAVDKVVDPE----VASAFKAELVKGVPIGRLGRPE
MAV_2726|M.avium_104 NIRVNVLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPV
MAB_0952|M.abscessus_ATCC_1997 GVTVNAILPGNILTEG---LVDMG------EEYISGMARSIPMGMLGSPV
MLBr_01807|M.leprae_Br4923 SITANVVAPGFIDTEMTRAMDSKY---------QEAALQAIPLGRIGAVE
.: .*.: .* : : :*: .
Mb1385|M.bovis_AF2122/97 EVASVAVFLASDLSSYMTGTVLDVTGGRFI---------
Rv1350|M.tuberculosis_H37Rv EVASVAVFLASDLSSYMTGTVLDVTGGRFI---------
MUL_3898|M.ulcerans_Agy99 EVASVALFLACDLSSYMTGTVLDVTGGRFI---------
Mflv_4369|M.gilvum_PYR-GCK EVAKVALFLASDLSSYMTGTVLEVTGGRHL---------
TH_3954|M.thermoresistible__bu EVAGAVVFLGSDLSSYITGSVIEVGGGRYM---------
MMAR_0587|M.marinum_M EIAAAVLFLASDQSSFMTGSEMFVDGGTEQL--------
MSMEG_6823|M.smegmatis_MC2_155 EIATAVLFLASNQSSFMTGAELVVDGGQIQI--------
Mvan_1616|M.vanbaalenii_PYR-1 EVAAAVAFLASADSSFIYGANLDIDGGEHQV--------
MAV_2726|M.avium_104 EIAHAAVFLASDLSSFCTGSTVTADGGFNQV--------
MAB_0952|M.abscessus_ATCC_1997 DIGHLAAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP
MLBr_01807|M.leprae_Br4923 EIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-------
::. . **. :.: * : **