For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TGLLSGKTVVISGVGTGLGREVALKAHQDGANVVLGARTRENLERLTTELDDTGGSATWAVTDITDATAC QGLIDTAVKRFGAVDALVNVAAKEDVFGGIEGADLAQWQAMLNTNVVGTLQLVQAAVPELKKKGGSVVFI GSQSAFHPQLPQSAYATSKGALQNAMYQLAKELGPHKIRLNMVVPTWMYGPPIQLYIGLVAQQRGITQEE VLAELTAKFPLGEMPADEDVADAVVFFVSDRARMVTGQTLFVNGGEFFR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0259c | - | - | 100% (260) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4178c | - | 1e-42 | 38.49% (252) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1219 | - | 4e-25 | 28.14% (263) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3560c | - | 1e-40 | 34.50% (258) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1530 | - | 1e-39 | 36.08% (255) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3530c | - | 1e-40 | 34.50% (258) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-13 | 26.29% (251) | 3-oxoacyl- |
| M. marinum M | MMAR_5018 | - | 9e-38 | 34.11% (258) | short-chain alcohol dehydrogenase |
| M. avium 104 | MAV_0630 | - | 4e-42 | 36.86% (255) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5931 | - | 2e-39 | 36.05% (258) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3268 | - | 3e-38 | 36.22% (254) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4092 | - | 4e-30 | 31.56% (244) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5228 | - | 3e-40 | 36.72% (256) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3560c|M.bovis_AF2122/97 ---MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDV
Rv3530c|M.tuberculosis_H37Rv ---MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDV
MMAR_5018|M.marinum_M ---MPGLLDGKTLVISGVGPGLGTTLAHRCAAEGADLVLAARSGDRLDEL
MUL_4092|M.ulcerans_Agy99 -----------------MGPGLGTTLAHRCAAEGADLVLAARIGDRLDEL
MAV_0630|M.avium_104 ------MLDGKVVVISGVGPGLGTTLAHRCADSGADLVLAARTAERLEKV
Mflv_1530|M.gilvum_PYR-GCK MSEALPLLENKVVVISGVGPALGTTLARRCAEAGADLVLAARTVERLEDV
Mvan_5228|M.vanbaalenii_PYR-1 --MAFGLLRDKVVVISGVGPALGTTLARRCAEEGADLVLAARTVERLDDV
MSMEG_5931|M.smegmatis_MC2_155 ---MGGLLTDKVVVISGVGPALGTTLARRCAEQGADLVLAARTVERLEDV
TH_3268|M.thermoresistible__bu --MTMLSLDNKVVVISGVGPALGTTLARRCAAAGADLVLAARTAERLEEV
MAB_0259c|M.abscessus_ATCC_199 ---MTGLLSGKTVVISGVGTGLGREVALKAHQDGANVVLGARTRENLERL
MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD
* . :: *.: :. .*
Mb3560c|M.bovis_AF2122/97 AKQIIDTGRRAVA------VRTDITDDDDVSNLVQATLAAYGKADVLINN
Rv3530c|M.tuberculosis_H37Rv AKQIIDTGRRAVA------VRTDITDDDDVSNLVQATLAAYGKADVLINN
MMAR_5018|M.marinum_M AKQIIDKGRQAIA------VRADITDDDQVSNLVDATLEAYGKIDVLVNN
MUL_4092|M.ulcerans_Agy99 AKQIIDKGRQAIA------VRADITDDDQVSNLVDATLEAYGKIDVLVNN
MAV_0630|M.avium_104 AKQVNDGGHRALA------VRTDITDDDEVAYLVETTMATYGRADVLINN
Mflv_1530|M.gilvum_PYR-GCK ATQITDLGRRAVS------VGTDITDEAQVANLVEESLKAYGKVDVLINN
Mvan_5228|M.vanbaalenii_PYR-1 ARQITDLGRRAVS------VGTDITDEAQVNNLVDESLKAYGKVDVLINN
MSMEG_5931|M.smegmatis_MC2_155 AKQVTDTGRRALS------VGTDITDDAQVAHLVDETMKAYGRVDVVINN
TH_3268|M.thermoresistible__bu AGQITATGRRAVA------VPTDITDEAQVANLVAETNKAYGRVDVLINN
MAB_0259c|M.abscessus_ATCC_199 TTELDDTGGSATW------AVTDITDATACQGLIDTAVKRFGAVDALVNV
MLBr_01807|M.leprae_Br4923 GHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVAN
.: : . *:** . * :.::
Mb3560c|M.bovis_AF2122/97 AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTP-ALAQSHGAIVN
Rv3530c|M.tuberculosis_H37Rv AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTP-ALAQSHGAIVN
MMAR_5018|M.marinum_M AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTR-ALAETNGSIVN
MUL_4092|M.ulcerans_Agy99 AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTR-ALAETNGSIVN
MAV_0630|M.avium_104 AFRVPSMKPLAGTSFQHIRDAIELSALGALRLIQAFTP-ALETAHGSIVN
Mflv_1530|M.gilvum_PYR-GCK AFRVPSMKPFANTTFEHMRDAIELTVFGALRMVQAFTP-ALAEANGAVVN
Mvan_5228|M.vanbaalenii_PYR-1 AFRVPSMKPFADTTFEHMRDAIELTVFGALRMVQAFSP-ALAEANGAVVN
MSMEG_5931|M.smegmatis_MC2_155 AFRVPSMKPFANTTFEHMRDAIELTVFGALRLIQGFTP-ALEESKGAVVN
TH_3268|M.thermoresistible__bu AFRVPSMKPLANTGFDHIREAIELTVLGALRLTQALTP-ALAQANGSVVN
MAB_0259c|M.abscessus_ATCC_199 AAKEDVFGGIEGADLAQWQAMLNTNVVGTLQLVQAAVP-ELKKKGGSVVF
MLBr_01807|M.leprae_Br4923 AG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIF
* : : : :: . *.::: : * :
Mb3560c|M.bovis_AF2122/97 VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW
Rv3530c|M.tuberculosis_H37Rv VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW
MMAR_5018|M.marinum_M VNSMVLRHSQPKFGAYKMAKSTLLAMSHSLAAELGVKGIRVNSVAPGYIW
MUL_4092|M.ulcerans_Agy99 VNSMVLRHSQPKFGADKTAKSTLLAMSHSLAAELGVKGIWVNSVAPGYIW
MAV_0630|M.avium_104 VNSMVLRHSQAKYGAYKMAKSALLSMSQSLATELGEKGIRVNSVAPGYIW
Mflv_1530|M.gilvum_PYR-GCK VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGDQGIRVNSVLPGYIW
Mvan_5228|M.vanbaalenii_PYR-1 VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEQGIRVNSVLPGYIW
MSMEG_5931|M.smegmatis_MC2_155 VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEKGIRVNSVLPGYIW
TH_3268|M.thermoresistible__bu VNSMVIRHSQPKYGAYKMAKAALLAMSQSLASELGEQGIRVNSVVPGYIW
MAB_0259c|M.abscessus_ATCC_199 IGSQSAFHPQLPQSAYATSKGALQNAMYQLAKELGPHKIRLNMVVPTWMY
MLBr_01807|M.leprae_Br4923 MGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFID
:.* . :*. * ** *** : * * * * ::
Mb3560c|M.bovis_AF2122/97 GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS
Rv3530c|M.tuberculosis_H37Rv GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS
MMAR_5018|M.marinum_M GDTLQGYFEHQAGKYGTTVEQIYQATAAQSDLKRLPTEDEVASAILFMAS
MUL_4092|M.ulcerans_Agy99 GDTLQGYFEHQAGKYGTTVEKIYQATAAQSDLKRLPTEDEVASAVLFMAS
MAV_0630|M.avium_104 GDTLQAYFEHQAGKYGTTVEQIYAATAANSDLKRLPTEDEVASAIMFLAS
Mflv_1530|M.gilvum_PYR-GCK GGTLESYFSHQAGKYGTTVDEIYKATAAASDLKRLPTEDEVASAILFMAC
Mvan_5228|M.vanbaalenii_PYR-1 GGTLESYFTHQAGKYGTTVEEIYKATAAASDLKRLPTEDEVASAILFMAS
MSMEG_5931|M.smegmatis_MC2_155 GGTLKSYFEHQAGKYGTSVEDIYNAAAAGSDLKRLPTEDEVASAILFMAS
TH_3268|M.thermoresistible__bu GETLKGYFQHQAGKYNTTVDQIYQATAAQSDLKRLPTEDEVASAILFFAS
MAB_0259c|M.abscessus_ATCC_199 GPPIQLYIGLVAQQRGITQEEVLAELTAKFPLGEMPADEDVADAVVFFVS
MLBr_01807|M.leprae_Br4923 TEMTR-----------AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLAS
. .. * .: : :::*.*: *:..
Mb3560c|M.bovis_AF2122/97 DLASGITGQTLDVNCGEYHT-
Rv3530c|M.tuberculosis_H37Rv DLASGITGQTLDVNCGEYHT-
MMAR_5018|M.marinum_M DLSSGITGQTLDVNCGEYHT-
MUL_4092|M.ulcerans_Agy99 DLSSGITGQTLDVNCGEYHT-
MAV_0630|M.avium_104 DLSSGITGQTLDVNCGEYHT-
Mflv_1530|M.gilvum_PYR-GCK DLSSGITGQALDVNCGEFKA-
Mvan_5228|M.vanbaalenii_PYR-1 DLSSGITGQALDVNCGEFKA-
MSMEG_5931|M.smegmatis_MC2_155 DLASGITGQALDVNCGEYKA-
TH_3268|M.thermoresistible__bu DLSSGITGQTLDVNCGEYKV-
MAB_0259c|M.abscessus_ATCC_199 DRARMVTGQTLFVNGGEFFR-
MLBr_01807|M.leprae_Br4923 EDAGYISGAVIPVDGGLGMGH
: : ::* .: *: *