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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4599 | - | - | 100% (277) | fatty-acid-CoA ligase |
| M. thermoresistible (build 8) | TH_3626 | - | 7e-54 | 42.46% (252) | PUTATIVE putative fatty-acid-CoA ligase |
| M. thermoresistible (build 8) | TH_3186 | - | 5e-41 | 39.38% (259) | PUTATIVE AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0172 | fadD5 | 9e-41 | 40.39% (255) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_4616 | - | 3e-48 | 42.23% (251) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0166 | fadD5 | 4e-41 | 40.78% (255) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_01051 | xclC | 3e-31 | 34.39% (253) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4569c | - | 3e-40 | 39.30% (257) | fatty-acid-CoA ligase FadD |
| M. marinum M | MMAR_1606 | - | 2e-86 | 63.35% (251) | fatty-acid-CoA ligase |
| M. avium 104 | MAV_5018 | - | 2e-40 | 38.82% (255) | acyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_0131 | - | 8e-43 | 41.18% (255) | acyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_3431 | - | 5e-84 | 60.94% (256) | fatty-acid-CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_3993 | - | 2e-43 | 39.06% (256) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1606|M.marinum_M ------------------------MTSLAGNLIEGARRHPNRIALRLDEI
MUL_3431|M.ulcerans_Agy99 ------------------------MTSLAGNLIEGARRHPNRIALRLDEI
TH_4599|M.thermoresistible__bu --------------------------------------------------
Mb0172|M.bovis_AF2122/97 MTAQLASHLTRALTLAQQQPYLARRQNWVNQLERHAMMQPDAPALRFVGN
Rv0166|M.tuberculosis_H37Rv MTAQLASHLTRALTLAQQQPYLARRQNWVNQLERHAMMQPDAPALRFVGN
MAV_5018|M.avium_104 -MLSLTAQLAHHPTQANEQPYLSRRQNWVNQLERHALMQPNATALRFLGK
MAB_4569c|M.abscessus_ATCC_199 ---MTDTIDATVQSAGLAQPYRARRQNWCNQLARHALMQPDATAIRYLGH
MSMEG_0131|M.smegmatis_MC2_155 ---------MTAEPSQIEQPYLARRQNWVNQLTRHAMMQPDKTALRFLGR
Mvan_3993|M.vanbaalenii_PYR-1 ---------------------MSDGMYLTQGLHRSLRATPDATMTICGER
Mflv_4616|M.gilvum_PYR-GCK ---------------------MDRG--IGQWVTKRAFLNGQRTALVQGDT
MLBr_01051|M.leprae_Br4923 -------------------------MLLASLNPSVVTATDIADAVCVDGV
MMAR_1606|M.marinum_M EIPYGALDAASARLAGLLIQRGLRPGDRVGVMLPNVPYFAVAYYGVLRAG
MUL_3431|M.ulcerans_Agy99 EIPYGALDTASARLAGLLIQRGLRPGDRVGVMLPNVPYFAVAYYGVLRAG
TH_4599|M.thermoresistible__bu --------------------------------------------------
Mb0172|M.bovis_AF2122/97 TMTWADLRRRVAALAGALSGRGVGFGDRVMILMLNRTEFVESVLAANMIG
Rv0166|M.tuberculosis_H37Rv TMTWADLRRRVAALAGALSGRGVGFGDRVMILMLNRTEFVESVLAANMIG
MAV_5018|M.avium_104 GLTWGELHGRVRALADALSRRGVGFGDRVMVLMLNRPEFMESVLAINMLG
MAB_4569c|M.abscessus_ATCC_199 SISWAELHQRVQALADALSRRGVGFGDRVLILMLNRPEYVESWLAINELG
MSMEG_0131|M.smegmatis_MC2_155 TTTWRELDDRVTRLAGALNRRGVGFGDRVLILMLNRTEFVEAMLAANRLG
Mvan_3993|M.vanbaalenii_PYR-1 VRTFADVGDRVSRLAGGFRSLGASPGDRIAILSLNSDRYQESLLATVWSG
Mflv_4616|M.gilvum_PYR-GCK SFTYSDFDRRTNQVASSLLRLGVRKGDRVAILLVNSVEFLEVLLGCAKIG
MLBr_01051|M.leprae_Br4923 VLSRSGLVGAATSVAERVGG-----ARLVAVLATPTASTVLAITGCLIAG
MMAR_1606|M.marinum_M GVVVPMNVLLKERETSFYLTDSEAKAIIAWHEFAPAAQAGADEAGAECIL
MUL_3431|M.ulcerans_Agy99 GVVVPMNVLLKERETSFYLTDSEAKAIIAWHEFVPAAQAGADEAGAECIL
TH_4599|M.thermoresistible__bu --------------------------------------------------
Mb0172|M.bovis_AF2122/97 AIAVPLNFRLTPTEIAVLVEDCAAHVMLTEAALAPVAI-GVRNIQPLLSV
Rv0166|M.tuberculosis_H37Rv AIAVPLNFRLTPTEIAVLVEDCVAHVMLTEAALAPVAI-GVRNIQPLLSV
MAV_5018|M.avium_104 AIAVPLNFRLTAAEIAFLVQDCQARVVITEAVLAPVAT-GVRDIESLLDT
MAB_4569c|M.abscessus_ATCC_199 AIAIPVNFRMTPPEVAFLVENSGAKVAITETVLAPVAA-AVRQQAPALET
MSMEG_0131|M.smegmatis_MC2_155 AIAVPVNFRMTPPEIAYLVSDCEAHVVVTEPVLAGVAT-AVRDLDATLQT
Mvan_3993|M.vanbaalenii_PYR-1 CVTNPVNIRWSAAEIAYALRDSDSRILLIDDAFLPMLP-ELRREFPGLGD
Mflv_4616|M.gilvum_PYR-GCK AITIPINVRLAGPEIGYILADSGADVFVFHAPLAAAAVSALTEPGVRVRH
MLBr_01051|M.leprae_Br4923 VPVVPVPADIGVVERRHMLTDSGAQAWLGPGPSADSAPDGLPHIPVQLDA
MMAR_1606|M.marinum_M VKPGE----------FEELIQAAEPLEEAAVREDDDTAVILYTSGTTGKP
MUL_3431|M.ulcerans_Agy99 VKPGE----------FEELIQAAEPLEEAAVREDDDTAVILYTSGTTGKP
TH_4599|M.thermoresistible__bu -----------------------------VIR---TIPVILYTSGTTGAP
Mb0172|M.bovis_AF2122/97 IVVAG-GSSQDSVFGYEDLLNEAGDVHEPVDIPNDSPALIMYTAGTTGRP
Rv0166|M.tuberculosis_H37Rv IVVAG-GSSQDSVFGYEDLLNEAGDVHEPVDIPNDSPALIMYTSGTTGRP
MAV_5018|M.avium_104 VVVAG-GSSDDAVLGYDDLIDETGAAHQPVDIPNDAAALIMYTSGTTGRP
MAB_4569c|M.abscessus_ATCC_199 VIVAG-SASENGVLGYEEVIAEPGEPHAEVDLPGDTPALIMYTSGTTGRP
MSMEG_0131|M.smegmatis_MC2_155 VIVAG-GATEDGVLGYDDLIAEEGEPPAPVDIPNDSPALIMYTSGTTGRP
Mvan_3993|M.vanbaalenii_PYR-1 VIHCGDGVAPPECLAFEDLLG-VSDPVTDAHRSGSDLAGVFYTGGTSGHP
Mflv_4616|M.gilvum_PYR-GCK TLRAG-GAPADGEIPYTDLLSDGAPAPLDSDVEGRDPAFIMYTSGTTGRP
MLBr_01051|M.leprae_Br4923 RSWNR-----------------------YPEPSPDATAMVIYTSGTTGPP
. ::**.**:* *
MMAR_1606|M.marinum_M KGAELTHANLRRNVEVIVQMLQVGPD-DVILGALPLFHAFGQTAGLNAAV
MUL_3431|M.ulcerans_Agy99 KGAELTHANLRRNVEVIVQMLQVGPD-DVILGALPLFHAFGQTAGLNAAV
TH_4599|M.thermoresistible__bu KGAQLTHSNLYRNALAFTGLFGLNRT-DVVLGTLPLFHAFGQSNALNASI
Mb0172|M.bovis_AF2122/97 KGAVLTHANLTGQAMTALYTSGANINSDVGFVGVPLFHIAGIG-NMLTGL
Rv0166|M.tuberculosis_H37Rv KGAVLTHANLTGQAMTALYTSGANINSDVGFVGVPLFHIAGIG-NMLTGL
MAV_5018|M.avium_104 KGAVLTHTNLTGQTMTGLYTNGADINNDVGFIGVPFFHIAGIG-NMLTGL
MAB_4569c|M.abscessus_ATCC_199 KGAVLTHLNLSGQAMTYLLSTTVDLNSDVGFIGVPMFHIAGVG-NMITGL
MSMEG_0131|M.smegmatis_MC2_155 KGAVLTHTNLSAQAMMHLFTTGADLNSDVGFVGVPLFHIAGVAGSVLSGV
Mvan_3993|M.vanbaalenii_PYR-1 KGVMLTHDNLMTSAMGALASGFFLTSGGPLLHAAPMFHLADLA-IWLEQV
Mflv_4616|M.gilvum_PYR-GCK KGAILTHDNLRWNAINVLGAEQGLTGSDVTVAVAPMFHIGGLGVHTLPLL
MLBr_01051|M.leprae_Br4923 KGVLLSRR-AIAVDLDALAQAWQWTADDVLVHGLPLFHVHGLVLGLLGSL
**. *:: . . *:** . :
MMAR_1606|M.marinum_M AAGACLTLIPR--FSPEKALQIIERDRVTVFEGVPTMFAAMLHS-TERP-
MUL_3431|M.ulcerans_Agy99 AAGACLTLIPR--FSPEKALQIIERDRVTVFEGVPTMFAAMLHS-TERP-
TH_4599|M.thermoresistible__bu AVGACVSLVPR--FDAAAVLRLIERHRVTVFAGVPTMYTAVLQA-EAGPT
Mb0172|M.bovis_AF2122/97 LLGLPTVIYPLGAFDPGQLLDVLEAEKVTGIFLVPAQWQAVCTEQQARPR
Rv0166|M.tuberculosis_H37Rv LLGLPTVIYPLGAFDPGQLLDVLEAEKVTGIFLVPAQWQAVCTEQQARPR
MAV_5018|M.avium_104 LLGIPTVIYPLGAFEPGQLLDVLAAEKVTGIFLVPAQWQAVCAEQRARPR
MAB_4569c|M.abscessus_ATCC_199 LLGLPTVIHPLGAFDPGALLDVLESEGVTGIFLVPAQWQAVCAAQQANPR
MSMEG_0131|M.smegmatis_MC2_155 TLGVPTVLYPLGAFDPDGLLDVLESEQVTGIFLVPAQWQAVCAAQRARPR
Mvan_3993|M.vanbaalenii_PYR-1 IRGGTHVFIPS--FKPEGVLDALQRHRVSDLLLVPTMVQMLVDHPALPVY
Mflv_4616|M.gilvum_PYR-GCK YVGGTSVILPS--FDPVGTLKAMAESRATVQFMVPAMWSALTQVPDFDSY
MLBr_01051|M.leprae_Br4923 RIGNRFVHTGKP--TPTAYAQACSEAGGSLYFGVPTVWSRLVAD-EAVAR
* . : **: :
MMAR_1606|M.marinum_M DTGSLRLCVSGGAAMPVEVMRGFEQAFG-TMVLEGYGLSETSPTASFNHP
MUL_3431|M.ulcerans_Agy99 DTGSLRLCVSGGAAMPVEVMRGFEQAFG-TMVLEGYGLSETSPTASFNHP
TH_4599|M.thermoresistible__bu DTSSLRICVSGGAPLPVEVLREFESTFG-AQILEGHGLSETSPTASFNPA
Mb0172|M.bovis_AF2122/97 D-LRLRVLSWGAAPAPDALLRQMSATFPETQILAAFGQTEMSPVTCMLLG
Rv0166|M.tuberculosis_H37Rv D-LRLRVLSWGAAPAPDALLRQMSATFPETQILAAFGQTEMSPVTCMLLG
MAV_5018|M.avium_104 D-LKLRVISWGAAPAPDALLREMSAMFPGTQILAAFGQTEMSPVTCMLLG
MAB_4569c|M.abscessus_ATCC_199 K-VRLKTLSWGAAPATDVLLRTMSETFPDARILAAFGQTEMSPVTCMLMG
MSMEG_0131|M.smegmatis_MC2_155 N-LKLRALSWGAAPASDTLLREMNEVFPDAQIFAAFGQTEMSPVTCMLLG
Mvan_3993|M.vanbaalenii_PYR-1 DTSALQMVMYGGSPIAAALLERASKRLPTASFVQAYGMTEVSPIATLLSP
Mflv_4616|M.gilvum_PYR-GCK DLSALRLAMGGGAPMPLTVIDFMHQRG--VPFTEGFGMTETAPMVSVLDA
MLBr_01051|M.leprae_Br4923 ALRPARLLVSGSASLPVPVFDRLAHLTG-HRPIERYGSTESLITLSTLAD
: *.:. . :: .* :*
MMAR_1606|M.marinum_M ----DRERKPGSIGTPI-AGVQMKLL-----EVDTH--GIGEIAIRGHNV
MUL_3431|M.ulcerans_Agy99 ----DRERKPGSIGTPI-AGVQMKLL-----EVDTH--GIGEIAIRGHNV
TH_4599|M.thermoresistible__bu ----GR-TKPGSIGLPLDAGIEMKVVDGDGIEVPTG--DVGEIVIRGHNV
Mb0172|M.bovis_AF2122/97 ---EDAIAKRGSVGRVI-PTVAARVVDQNMNDVPVG--EVGEIVYRAPTL
Rv0166|M.tuberculosis_H37Rv ---EDAIAKRGSVGRVI-PTVAARVVDQNMNDVPVG--EVGEIVYRAPTL
MAV_5018|M.avium_104 ---EDAIRKRGSVGKVI-PTVAARVVDENMNDVPVG--EVGEIVYRAPTL
MAB_4569c|M.abscessus_ATCC_199 ---DDAIRKMGSVGRVI-PTVSARVVDDNMNDVPVG--EVGEIVYRAPTL
MSMEG_0131|M.smegmatis_MC2_155 ---DDAIRKLGSVGRVI-PTVSARVVDDNMNDVPVG--EVGEIVYRGPNL
Mvan_3993|M.vanbaalenii_PYR-1 RDHDDPVLRR-SGGVAA-PHSEVRIVDEDDVEVPRG--DVGEITVRGGHV
Mflv_4616|M.gilvum_PYR-GCK ---ANITTRAGSIGRVA-MHVDARIVDADDRDVPAD--TVGELLVRGPNV
MLBr_01051|M.leprae_Br4923 -----GERRAGWVGLPL-AGVQTRLVDESGGPVPYDGETVGRLQVRSPTM
: * ::: * :*.: *. :
MMAR_1606|M.marinum_M MKGYWNRPDATAAAIDAEGWFRTGDLARIDEDGYYFIVDRS-KDMIIRGG
MUL_3431|M.ulcerans_Agy99 MKGYWNRPDATAAVIDAEGWFRTGDLARIDEDGYYFIVDRS-KDMII---
TH_4599|M.thermoresistible__bu MKGYWNRPDETAAAIN-DGWFHTGDMAVRDEDGFFFIVDRK-KDVIIR--
Mb0172|M.bovis_AF2122/97 MSCYWNNPEATAEAFA-GGWFHSGDLVRMDSDGYVWVVDRK-KDMIISGG
Rv0166|M.tuberculosis_H37Rv MSCYWNNPEATAEAFA-GGWFHSGDLVRMDSDGYVWVVDRK-KDMIISGG
MAV_5018|M.avium_104 MSGYWNNPEATAEAFA-GGWFHSGDLVRMDEDGYVWVVDRK-KDMIISGG
MAB_4569c|M.abscessus_ATCC_199 MQGYWNNPEATADAFA-GGWFHSGDLVRQDEDGFVWVVDRK-KDMIISGG
MSMEG_0131|M.smegmatis_MC2_155 MVGYWNNPKATAEAFA-GGWFHSGDLVRQDEEGYVWVVDRK-KDMIISGG
Mvan_3993|M.vanbaalenii_PYR-1 MAGYWGRPEDTATALR-GGWMHTGDAGYMDERGYVFVVDRI-KDMIVSGG
Mflv_4616|M.gilvum_PYR-GCK FVGYWMKPATTAEAFR-GGWFHTGDLGRIDADGYITLVDRK-KDMIISGG
MLBr_01051|M.leprae_Br4923 FGGYLNRPEATAEAFDEDGWYRTGDVAVVDSGGMHRIVGRESVDLIKLGG
: * .* ** .: ** ::** * * :*.* *:*
MMAR_1606|M.marinum_M YNVYPREIEEVLYEHPEVREAAVVAVPDDMLGEEVGAAIALIPGAT----
MUL_3431|M.ulcerans_Agy99 --------------------------------------------------
TH_4599|M.thermoresistible__bu --------------------------------------------------
Mb0172|M.bovis_AF2122/97 ENIYCAELENVLASHPDIAEVAVIGRADEKWGEVPIAVAAVTND------
Rv0166|M.tuberculosis_H37Rv ENIYCAELENVLASHPDIAEVAVIGRADEKWGEVPIAVAAVTND------
MAV_5018|M.avium_104 ENIYCAEVENVLASHPDIVEVAVIGRAHEKWGEVPIAVAAVAND------
MAB_4569c|M.abscessus_ATCC_199 ENIYCAEVENALAEHEQIAEVAVIGRPHEKWGEVPVAVAAIHGA------
MSMEG_0131|M.smegmatis_MC2_155 ENIYCAEVENVLAAHPAIMEVAVIGRPHEKWGEVPVAVVALNSAT---AE
Mvan_3993|M.vanbaalenii_PYR-1 ENVYSVEVENALARHPAVAACAVIGVPDERWGERVHAVVVPSAEGGADAR
Mflv_4616|M.gilvum_PYR-GCK ENVYPIEVEQVLFRHPGVLDAAVVGGPDDKWGERVVAVVVADPAAE---Q
MLBr_01051|M.leprae_Br4923 YRIGAGEIEMALLGHPDVREVAVVGLPDEDLGQRIVAFVVGAEA------
MMAR_1606|M.marinum_M -SDAAALSDFVKERVAAYKYPRRIWFVDELPKGPTGKILKRDITVPQASP
MUL_3431|M.ulcerans_Agy99 ------LSDFVKERVAAYKYPRRIWFVDELPKGPTGKILKRDITVPQASP
TH_4599|M.thermoresistible__bu -------GGYTSIRVNSRRSS---------------------TNIPRCGR
Mb0172|M.bovis_AF2122/97 DLRIEDLGEFLTDRLARYKHPKALEIVDALPRNPAGKVLKTELRLRYGAC
Rv0166|M.tuberculosis_H37Rv DLRIEDLGEFLTDRLARYKHPKALEIVDALPRNPAGKVLKTELRLRYGAC
MAV_5018|M.avium_104 NLALEDLDEFLTERLARYKHPKALEIVDALPRNPAGKVLKTELRIRYGGG
MAB_4569c|M.abscessus_ATCC_199 ALTLAELDGFLTARLARYKHPKDLVIVDALPRNPSGKVLKTELRQRFGIA
MSMEG_0131|M.smegmatis_MC2_155 SISLGELDSFLTERLARYKHPKALEVVDALPRNPSGKVLKTELRERFGRA
Mvan_3993|M.vanbaalenii_PYR-1 NLDPEELREFCRSLIGGYKVPRTVEVVAALPLSAAGKVLKRELRARYWEG
Mflv_4616|M.gilvum_PYR-GCK EPSADELIAWCRERLAHFKCPREVHLLPELPRNATGKLLKTELRKRFTGV
MLBr_01051|M.leprae_Br4923 -LDADELINYVAQQLSIHKRPREVRFVDALPRNAMGKVLKKQLLFEG---
: : : .
MMAR_1606|M.marinum_M AQQ-------------------
MUL_3431|M.ulcerans_Agy99 AQQ-------------------
TH_4599|M.thermoresistible__bu PR--------------------
Mb0172|M.bovis_AF2122/97 VNVERRSASAGFTERRENRQKL
Rv0166|M.tuberculosis_H37Rv VNVERRSASAGFTERRENRQKL
MAV_5018|M.avium_104 ----------------------
MAB_4569c|M.abscessus_ATCC_199 D---------------------
MSMEG_0131|M.smegmatis_MC2_155 TSLDGGESNSATTVSAG-----
Mvan_3993|M.vanbaalenii_PYR-1 SDRSVG----------------
Mflv_4616|M.gilvum_PYR-GCK EGGVVQR---------------
MLBr_01051|M.leprae_Br4923 ----------------------