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M. gilvum PYR-GCK Mflv_4616 (-)

annotation: AMP-dependent synthetase and ligase
coordinates: 4914792 - 4916348
length: 518

MDRGIGQWVTKRAFLNGQRTALVQGDTSFTYSDFDRRTNQVASSLLRLGVRKGDRVAILLVNSVEFLEVL
LGCAKIGAITIPINVRLAGPEIGYILADSGADVFVFHAPLAAAAVSALTEPGVRVRHTLRAGGAPADGEI
PYTDLLSDGAPAPLDSDVEGRDPAFIMYTSGTTGRPKGAILTHDNLRWNAINVLGAEQGLTGSDVTVAVA
PMFHIGGLGVHTLPLLYVGGTSVILPSFDPVGTLKAMAESRATVQFMVPAMWSALTQVPDFDSYDLSALR
LAMGGGAPMPLTVIDFMHQRGVPFTEGFGMTETAPMVSVLDAANITTRAGSIGRVAMHVDARIVDADDRD
VPADTVGELLVRGPNVFVGYWMKPATTAEAFRGGWFHTGDLGRIDADGYITLVDRKKDMIISGGENVYPI
EVEQVLFRHPGVLDAAVVGGPDDKWGERVVAVVVADPAAEQEPSADELIAWCRERLAHFKCPREVHLLPE
LPRNATGKLLKTELRKRFTGVEGGVVQR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4616--100% (518)AMP-dependent synthetase and ligase
M. gilvum PYR-GCKMflv_0714-5e-9740.39% (510) acyl-CoA synthetase
M. gilvum PYR-GCKMflv_4559-1e-9038.75% (511) acyl-CoA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0172fadD58e-9540.23% (512) acyl-CoA synthetase
M. tuberculosis H37RvRv0166fadD58e-9540.43% (512) acyl-CoA synthetase
M. leprae Br4923MLBr_02546fadD26e-5732.34% (501) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_2063c-1e-15477.65% (340) acid-CoA ligase
M. marinum MMMAR_0409fadD52e-9539.96% (508) fatty-acid-CoA ligase FadD5
M. avium 104MAV_5018-6e-9440.00% (515) acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_0131-1e-10842.11% (513) acyl-CoA synthetase
M. thermoresistible (build 8)TH_2878-1e-9841.22% (507) PUTATIVE AMP-binding enzyme, putative
M. ulcerans Agy99MUL_4126fadD31e-6435.76% (495) acyl-CoA synthetase
M. vanbaalenii PYR-1Mvan_4008-1e-10142.04% (509) AMP-dependent synthetase and ligase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4616|M.gilvum_PYR-GCK          -------------------------------------------MDRGIGQ
MAB_2063c|M.abscessus_ATCC_199      -------------------------------------------MQLGIGQ
Mb0172|M.bovis_AF2122/97            --------------------MTAQLASHLTRALTLAQQQPYLARRQNWVN
Rv0166|M.tuberculosis_H37Rv         --------------------MTAQLASHLTRALTLAQQQPYLARRQNWVN
MMAR_0409|M.marinum_M               --------------------MTAELASHLPQAA-HALEQPYLARRQNWVN
MAV_5018|M.avium_104                ---------------------MLSLTAQLAHHPTQANEQPYLSRRQNWVN
MSMEG_0131|M.smegmatis_MC2_155      -----------------------------MTAEPSQIEQPYLARRQNWVN
TH_2878|M.thermoresistible__bu      ------------------------------------LQQPYLARRQNWVN
Mvan_4008|M.vanbaalenii_PYR-1       -----------------------------------------MITGITLSD
MUL_4126|M.ulcerans_Agy99           ----------------------------------------MTSDPRTVPT
MLBr_02546|M.leprae_Br4923          MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          WVTKRAFLNGQRTALVQGDTSFTYSDFDRRTNQVASSLLRLGVRKGDRVA
MAB_2063c|M.abscessus_ATCC_199      WVTRRAFLNGGRTALISNGAHITYADLDRRTNQVAAALIALGVRKGDRVA
Mb0172|M.bovis_AF2122/97            QLERHAMMQPDAPALRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVM
Rv0166|M.tuberculosis_H37Rv         QLERHAMMQPDAPALRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVM
MMAR_0409|M.marinum_M               QLERHAMMQPRATAIRYLGHTVTWADLRYRVAALAGSLSRRGVGFGDRVM
MAV_5018|M.avium_104                QLERHALMQPNATALRFLGKGLTWGELHGRVRALADALSRRGVGFGDRVM
MSMEG_0131|M.smegmatis_MC2_155      QLTRHAMMQPDKTALRFLGRTTTWRELDDRVTRLAGALNRRGVGFGDRVL
TH_2878|M.thermoresistible__bu      HLARHALMQPDATALRFMGQTTTWADLHHRVNRLAGALRRRGVEFGDRVL
Mvan_4008|M.vanbaalenii_PYR-1       ALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAARGVRSGDRVA
MUL_4126|M.ulcerans_Agy99           ALDRLVRRLPNHDALVTDERSFTVSELNDEVYRAAAALIELGVKPAARVG
MLBr_02546|M.leprae_Br4923          LPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIA
                                         .       *:       *  ::   .   * .*   **  .  : 

Mflv_4616|M.gilvum_PYR-GCK          ILLVNSVEFLEVLLGCAKIGAITIPINVRLAGPEIGYILADSGADVFVFH
MAB_2063c|M.abscessus_ATCC_199      MLLVNSTEFIQVLLGCAKIGALAVPLNVRLAGPEIGYILADSGADVLVFH
Mb0172|M.bovis_AF2122/97            ILMLNRTEFVESVLAANMIGAIAVPLNFRLTPTEIAVLVEDCAAHVMLTE
Rv0166|M.tuberculosis_H37Rv         ILMLNRTEFVESVLAANMIGAIAVPLNFRLTPTEIAVLVEDCVAHVMLTE
MMAR_0409|M.marinum_M               ILMLNRTEFVESVLAANMLGAIAVPLNFRLTPSEIAFLVEDCAPRLVITE
MAV_5018|M.avium_104                VLMLNRPEFMESVLAINMLGAIAVPLNFRLTAAEIAFLVQDCQARVVITE
MSMEG_0131|M.smegmatis_MC2_155      ILMLNRTEFVEAMLAANRLGAIAVPVNFRMTPPEIAYLVSDCEAHVVVTE
TH_2878|M.thermoresistible__bu      ILMLNRTEFIETMLAANRLGAIAVPVNFRMTPPEIAFLAKDCEAKVIATE
Mvan_4008|M.vanbaalenii_PYR-1       VLGLNSIELVESWLAAHRLGAIAVPVNFRLAAGEIGYVLSDSAATAIVVD
MUL_4126|M.ulcerans_Agy99           IWSPNTWHWVVACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLFAM
MLBr_02546|M.leprae_Br4923          ILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIYD
                                    :   *    :    .   :**  : :* . :  :   :     .  .   

Mflv_4616|M.gilvum_PYR-GCK          APLAA--AAVSALTEPGVRVRHTLRAGGAPADG---EIPYTDLLSDGAPA
MAB_2063c|M.abscessus_ATCC_199      EPFAA--QAKSAVTESGVRVRHVVRAGGAPAPG---ELGYEDVVSGAAPE
Mb0172|M.bovis_AF2122/97            AALAP--VAI-GVRNIQPLLSVIVVAGGSSQDS---VFGYEDLLNEAGDV
Rv0166|M.tuberculosis_H37Rv         AALAP--VAI-GVRNIQPLLSVIVVAGGSSQDS---VFGYEDLLNEAGDV
MMAR_0409|M.marinum_M               EVLAQ--VAV-GVREIAPALSTIVVAGGASDPT---VVGYDELISETGDP
MAV_5018|M.avium_104                AVLAP--VAT-GVRDIESLLDTVVVAGGSSDDA---VLGYDDLIDETGAA
MSMEG_0131|M.smegmatis_MC2_155      PVLAG--VAT-AVRDLDATLQTVIVAGGATEDG---VLGYDDLIAEEGEP
TH_2878|M.thermoresistible__bu      PVLAG--VAT-AVRDLAPSLSSVIVAGAADGSDTPDVLDYEALIAEPGED
Mvan_4008|M.vanbaalenii_PYR-1       VALES--MVV-QVRQQVPALHTVVTIGG----------NLEQTIAAADPD
MUL_4126|M.ulcerans_Agy99           GHFLGSDRVAGLDRKALPALRHIVRIPIEEPDG-TWDEFIETGTDTGAVT
MLBr_02546|M.leprae_Br4923          DEYTK---VVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSSSA
                                            .          :                              

Mflv_4616|M.gilvum_PYR-GCK          PLDSDVEGRDPAFIMYTSGTTGRPKGAILTHDNLRWNAINVLGAEQGLTG
MAB_2063c|M.abscessus_ATCC_199      PLNGDVDGSDPAFIMYTSGTTGRPKGAILTHDNLLWNAINVLGTDIGLRG
Mb0172|M.bovis_AF2122/97            HEPVDIPNDSPALIMYTAGTTGRPKGAVLTHANLTGQAMTALYTSGANIN
Rv0166|M.tuberculosis_H37Rv         HEPVDIPNDSPALIMYTSGTTGRPKGAVLTHANLTGQAMTALYTSGANIN
MMAR_0409|M.marinum_M               PEPVDIPNDSPALIMYTSGTTGRPKGAVLTHTNLTGQVMTALYTGGANIN
MAV_5018|M.avium_104                HQPVDIPNDAAALIMYTSGTTGRPKGAVLTHTNLTGQTMTGLYTNGADIN
MSMEG_0131|M.smegmatis_MC2_155      PAPVDIPNDSPALIMYTSGTTGRPKGAVLTHTNLSAQAMMHLFTTGADLN
TH_2878|M.thermoresistible__bu      PPPVDIPDDSPALIMYTSGTTGNPKGAVLTHSNLTGQAMTNLFTIGVDLA
Mvan_4008|M.vanbaalenii_PYR-1       LPQCAVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSD
MUL_4126|M.ulcerans_Agy99           ARAAAVSPDDVSDILFTSGTTGRSKGVLCAHR-QSLSASASWAANGKITA
MLBr_02546|M.leprae_Br4923          PAPKVR--KRASIIILTSGTTGTPKGAN-RNTPASLAPLGGILSKVPFRA
                                               : *: *:**** .**.   :            :      

Mflv_4616|M.gilvum_PYR-GCK          SDVTVAVAPMFHIGGLGVHTLPLLYVGGTSVILP--SFDPVGTLKAMAES
MAB_2063c|M.abscessus_ATCC_199      EDVTVAVAPMFHIGGLGVHTLPLLYVGGTSVIMP--SFEPRATLQAMADH
Mb0172|M.bovis_AF2122/97            SDVGFVGVPLFHIAGIG-NMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAE
Rv0166|M.tuberculosis_H37Rv         SDVGFVGVPLFHIAGIG-NMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAE
MMAR_0409|M.marinum_M               SDVGFIGVPFFHIAGIG-NMLSGMLLGVPTVIYPLGAFNPGQLLDVLEAE
MAV_5018|M.avium_104                NDVGFIGVPFFHIAGIG-NMLTGLLLGIPTVIYPLGAFEPGQLLDVLAAE
MSMEG_0131|M.smegmatis_MC2_155      SDVGFVGVPLFHIAGVAGSVLSGVTLGVPTVLYPLGAFDPDGLLDVLESE
TH_2878|M.thermoresistible__bu      NDVGFIGVPLFHIAGIAGNVLSGLTLGLPTVLYPLGAFDPGGLLDVLEAE
Mvan_4008|M.vanbaalenii_PYR-1       DDCWMAVAPLFHTAGVS-GMLPMFLTGGKTVIPPSGGFDPDATIAAVVDE
MUL_4126|M.ulcerans_Agy99           DDRHLCINPFFHNFGYKAGILACLQTG--ATLFPHLTFDPLRTLQAIERH
MLBr_02546|M.leprae_Br4923          HEVTLLPAPMFHALGYLHATLAMFLGS---TLVLRRRFKPATVLEDIEKH
                                     :  .   *:**  *     *. .  .   .:     *.*   :  :   

Mflv_4616|M.gilvum_PYR-GCK          RATVQFMVPAMWSALTQVPD--FDSYDLSALRLAMGGGAPMPLTVIDFMH
MAB_2063c|M.abscessus_ATCC_199      HVTVQFMVPAMWTALTQVSD--FDSFNLSALRFAMGGGSPVPLTVSDFMR
Mb0172|M.bovis_AF2122/97            KVTGIFLVPAQWQAVCTEQQ--ARPRDLR-LRVLSWGAAPAPDALLRQMS
Rv0166|M.tuberculosis_H37Rv         KVTGIFLVPAQWQAVCTEQQ--ARPRDLR-LRVLSWGAAPAPDALLRQMS
MMAR_0409|M.marinum_M               RVSGIFLVPAQWQAVCAEQQ--ARPRELS-LRVMSWGAAPAPDALLRQMS
MAV_5018|M.avium_104                KVTGIFLVPAQWQAVCAEQR--ARPRDLK-LRVISWGAAPAPDALLREMS
MSMEG_0131|M.smegmatis_MC2_155      QVTGIFLVPAQWQAVCAAQR--ARPRNLK-LRALSWGAAPASDTLLREMN
TH_2878|M.thermoresistible__bu      KVTGIFLVPAQWQAVCAEQR--ARPRDLR-LRALSWGAAPASDTLLQEMT
Mvan_4008|M.vanbaalenii_PYR-1       QVTSCWMTPAQWQSVCALPG--LAAHDLSRLRRVWWGAAPASTTLLRTMI
MUL_4126|M.ulcerans_Agy99           RITVLPGPPTIYQTLLDHPA--RDDYDLSSLRFAVTGAATVPVVLVERMQ
MLBr_02546|M.leprae_Br4923          QATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGAELATRAL
                                    : :     *.    :           :*  **    ..:     :     

Mflv_4616|M.gilvum_PYR-GCK          Q--RGVPFTEGFGMTETAPMVSVLDAAN-ITTRAGSIGRVAMHVDARIVD
MAB_2063c|M.abscessus_ATCC_199      E--RGVPFTEGFGMTETAPLVTVLDAEN-ISTRAGSIGRVAMHVDG----
Mb0172|M.bovis_AF2122/97            ATFPETQILAAFGQTEMSPVTCMLLGED-AIAKRGSVGRVIPTVAARVVD
Rv0166|M.tuberculosis_H37Rv         ATFPETQILAAFGQTEMSPVTCMLLGED-AIAKRGSVGRVIPTVAARVVD
MMAR_0409|M.marinum_M               EVFPGTQIMAAFGQTEMSPVTCMLLGED-AIRKRGSVGKVIPTVSARVVD
MAV_5018|M.avium_104                AMFPGTQILAAFGQTEMSPVTCMLLGED-AIRKRGSVGKVIPTVAARVVD
MSMEG_0131|M.smegmatis_MC2_155      EVFPDAQIFAAFGQTEMSPVTCMLLGDD-AIRKLGSVGRVIPTVSARVVD
TH_2878|M.thermoresistible__bu      EVFPGTKIFAAFGQTEMSPVTCMLLAED-AVRKLGSVGKVIPTVAARIVD
Mvan_4008|M.vanbaalenii_PYR-1       DTFTGAEIIAAFGQTECSPITCLLRGED-AIAKIGSVGTPMLNVEVRVVD
MUL_4126|M.ulcerans_Agy99           SELDIDIVLTAYGLTEANGMGTMCRADDDALTVATTCGRPFADFELRIG-
MLBr_02546|M.leprae_Br4923          EE-LGPVIYNMYGSTEIA-FATIAGPKD-LQINSATVGPVVKGVKVKILD
                                           .   :* **   .  :    :       : *     .      

Mflv_4616|M.gilvum_PYR-GCK          ADDRDVPADTVGELLVRGPNVFVGYWMKPATTAEAF-RGGWFHTGDLGRI
MAB_2063c|M.abscessus_ATCC_199      --------------VARG-------LVPHGRSRAHG-RGGLHHP----RR
Mb0172|M.bovis_AF2122/97            QNMNDVPVGEVGEIVYRAPTLMSCYWNNPEATAEAF-AGGWFHSGDLVRM
Rv0166|M.tuberculosis_H37Rv         QNMNDVPVGEVGEIVYRAPTLMSCYWNNPEATAEAF-AGGWFHSGDLVRM
MMAR_0409|M.marinum_M               DEMNDVPIGQVGEIVYRAPTLMSGYWNNPDATAEAF-AGGWFHSGDLVRM
MAV_5018|M.avium_104                ENMNDVPVGEVGEIVYRAPTLMSGYWNNPEATAEAF-AGGWFHSGDLVRM
MSMEG_0131|M.smegmatis_MC2_155      DNMNDVPVGEVGEIVYRGPNLMVGYWNNPKATAEAF-AGGWFHSGDLVRQ
TH_2878|M.thermoresistible__bu      DTMNDVPVGEVGEIVYRAPTLMAGYWNNPQATAEAF-AGGWFHSGDLVRQ
Mvan_4008|M.vanbaalenii_PYR-1       DEMNDVDRGEVGEIVYLGPLVMKEYWNKAAETAEAF-RGGWFHSGDLVRQ
MUL_4126|M.ulcerans_Agy99           --------PDTGEVLLRGPNVMLGYLDDPRATAAAIDADGWLHTGDIGVL
MLBr_02546|M.leprae_Br4923          DSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQ----IIDGLLSSGDVGYF
                                                  .                       .*   .      

Mflv_4616|M.gilvum_PYR-GCK          DADGYITLVDRKKDMIISGGENVYPIEVEQVLFRHPGVLDAAVVGGPDDK
MAB_2063c|M.abscessus_ATCC_199      PQEGHDHLRRRE---------------------RLP--------------
Mb0172|M.bovis_AF2122/97            DSDGYVWVVDRKKDMIISGGENIYCAELENVLASHPDIAEVAVIGRADEK
Rv0166|M.tuberculosis_H37Rv         DSDGYVWVVDRKKDMIISGGENIYCAELENVLASHPDIAEVAVIGRADEK
MMAR_0409|M.marinum_M               DEDGYVWVVDRKKDMIISGGENVYCAEVENVLASHPSIVEVAVIGRADEK
MAV_5018|M.avium_104                DEDGYVWVVDRKKDMIISGGENIYCAEVENVLASHPDIVEVAVIGRAHEK
MSMEG_0131|M.smegmatis_MC2_155      DEEGYVWVVDRKKDMIISGGENIYCAEVENVLAAHPAIMEVAVIGRPHEK
TH_2878|M.thermoresistible__bu      DEEGYIWVVDRKKDMIISGGENIYCAEVENVLAAHPAVAEVAVVGRPHEK
Mvan_4008|M.vanbaalenii_PYR-1       DADGYFYVVDRKKDMIISGGENIYSAEVENVVATHPLVAEVAVIGVPHPK
MUL_4126|M.ulcerans_Agy99           DEAGNLRITDRLKDMYICGGFNVYPAEVEQVLARLDGVADVAVIGIPDHR
MLBr_02546|M.leprae_Br4923          DEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKE
                                       .   :  *                                       

Mflv_4616|M.gilvum_PYR-GCK          WGERVVAVVVADPAAEQEPSADELIAWCRERLAHFKCPREVHLLPELPRN
MAB_2063c|M.abscessus_ATCC_199      --DRGRAGPLPPPGG---------VRRRRDRR------------------
Mb0172|M.bovis_AF2122/97            WGEVPIAVAAVTN---DDLRIEDLGEFLTDRLARYKHPKALEIVDALPRN
Rv0166|M.tuberculosis_H37Rv         WGEVPIAVAAVTN---DDLRIEDLGEFLTDRLARYKHPKALEIVDALPRN
MMAR_0409|M.marinum_M               WGEVPIAVAAVTK---DHLRIEDLDEYLTERLARYKHPKALEIVDALPRN
MAV_5018|M.avium_104                WGEVPIAVAAVAN---DNLALEDLDEFLTERLARYKHPKALEIVDALPRN
MSMEG_0131|M.smegmatis_MC2_155      WGEVPVAVVALNSATAESISLGELDSFLTERLARYKHPKALEVVDALPRN
TH_2878|M.thermoresistible__bu      WGEVPVAVVALN--PDAELTMAELEEFLADRLARYKHPKVLEIVDALPRN
Mvan_4008|M.vanbaalenii_PYR-1       WGETPVAVIVPRE-PTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRN
MUL_4126|M.ulcerans_Agy99           LGEVGRAFIVARP--GFNLDEKSVIDYTREHLANFKAPRSVRFVDTLPRN
MLBr_02546|M.leprae_Br4923          WGARLRAFVVKKQ--DATIDEDAIKAYVRDHLARYKVPREVIFLEELPRN
                                          *                       :                   

Mflv_4616|M.gilvum_PYR-GCK          ATGKLLKTELRKRFTGVEGGVVQR--------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            PAGKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL-----------
Rv0166|M.tuberculosis_H37Rv         PAGKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL-----------
MMAR_0409|M.marinum_M               PSGKVLKTELRLRYGVGVYSESRSVSRSFEFREGS---------------
MAV_5018|M.avium_104                PAGKVLKTELRIRYGGG---------------------------------
MSMEG_0131|M.smegmatis_MC2_155      PSGKVLKTELRERFGRATSLDGGESNSATTVSAG----------------
TH_2878|M.thermoresistible__bu      PAGKVLKTELRARFAAGPSAEKEQSSSGATTSAGSS--------------
Mvan_4008|M.vanbaalenii_PYR-1       AAGKVLKGRLRDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEA
MUL_4126|M.ulcerans_Agy99           AGGKVVKPQLRELA------------------------------------
MLBr_02546|M.leprae_Br4923          PTGKVLKRELRDFEVH----------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       LVDVPSGRRWTYAELNAEIDSLARALMAIGIEKGDRVGIWAPNCPEWTML
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       QYATAKIGAILVTINPAYRTHELAYVLRHSAVRLLVSATEFKTSDYRAMV
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       AEVRPELPGLAEVLFLATEDWARLGERADLVSEDELRCRVRSLTPGDAIN
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       IQYTSGTTGSPKGATLSHRNILNNGYFVTDLIDFGPGDRLCIPVPFYHCF
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       GMVMGNLGCTTHGATMVIPAAGFDPAATLAAIEKEHCTAVYGVPTMFIAM
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       LGHPDLADCDVTSLRTGIMAGSPCPVEVMKRCVNELKMSEVGIAYGMTET
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       SPVSCQTRIEDDLDRRTATVGRAHPHVEIKIVDPDTGEIVKRGTAGEFCT
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       RGYSVMLGYWGDEDRTREAVDADGWMHTGDLAVMRDDGYCMIVGRIKDMV
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       IRGGENVYPREIEEFLHTHPDIDDVQVIGVPDERYGEEICAWIKVRAGAA
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_2063c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0172|M.bovis_AF2122/97            --------------------------------------------------
Rv0166|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0409|M.marinum_M               --------------------------------------------------
MAV_5018|M.avium_104                --------------------------------------------------
MSMEG_0131|M.smegmatis_MC2_155      --------------------------------------------------
TH_2878|M.thermoresistible__bu      --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1       PLDAHAVREFAAGKLAHYKIPRYVHMTDDFPMTVTGKVRKIDMRAETVRI
MUL_4126|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02546|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4616|M.gilvum_PYR-GCK          ---
MAB_2063c|M.abscessus_ATCC_199      ---
Mb0172|M.bovis_AF2122/97            ---
Rv0166|M.tuberculosis_H37Rv         ---
MMAR_0409|M.marinum_M               ---
MAV_5018|M.avium_104                ---
MSMEG_0131|M.smegmatis_MC2_155      ---
TH_2878|M.thermoresistible__bu      ---
Mvan_4008|M.vanbaalenii_PYR-1       LGL
MUL_4126|M.ulcerans_Agy99           ---
MLBr_02546|M.leprae_Br4923          ---