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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4578 | - | - | 100% (392) | alcohol dehydrogenase B |
| M. thermoresistible (build 8) | TH_2499 | - | e-105 | 52.43% (391) | PUTATIVE Alcohol dehydrogenase GroES domain protein |
| M. thermoresistible (build 8) | TH_2786 | - | 2e-97 | 48.97% (388) | PUTATIVE Alcohol dehydrogenase GroES domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3113 | adhD | 3e-97 | 47.68% (388) | zinc-type alcohol dehydrogenase AdhD |
| M. gilvum PYR-GCK | Mflv_1486 | - | 1e-100 | 48.85% (391) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3086 | adhD | 4e-97 | 47.68% (388) | zinc-type alcohol dehydrogenase AdhD |
| M. leprae Br4923 | MLBr_01784 | adhE2 | 2e-46 | 31.82% (374) | putative alcohol dehydrogenase (Zn dependent) |
| M. abscessus ATCC 19977 | MAB_2084 | - | 8e-93 | 46.92% (390) | zinc-type alcohol dehydrogenase AdhD |
| M. marinum M | MMAR_3997 | adhB_1 | 1e-106 | 49.36% (391) | zinc-containing alcohol dehydrogenase NAD dependent AdhB_1 |
| M. avium 104 | MAV_5214 | - | 1e-141 | 62.24% (384) | alcohol dehydrogenase B |
| M. smegmatis MC2 155 | MSMEG_3388 | - | 6e-98 | 48.08% (391) | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol |
| M. ulcerans Agy99 | MUL_3861 | adhB_1 | 1e-104 | 48.85% (391) | zinc-containing alcohol dehydrogenase NAD dependent AdhB_1 |
| M. vanbaalenii PYR-1 | Mvan_5270 | - | 1e-102 | 49.62% (391) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4578|M.thermoresistible__bu -------------------------------------------MRTKAAV
MAV_5214|M.avium_104 -------------------------------------------------M
Mb3113|M.bovis_AF2122/97 -------------------------------------------MKTTAAV
Rv3086|M.tuberculosis_H37Rv -------------------------------------------MKTTAAV
MSMEG_3388|M.smegmatis_MC2_155 MHSDPSHIDLLGPATFTSRDRRPIGFPPLRCSRHKISWKEPSEMKTKAAV
Mflv_1486|M.gilvum_PYR-GCK -------------------------------------------MKTNAAI
Mvan_5270|M.vanbaalenii_PYR-1 -------------------------------------------MKTNAAI
MAB_2084|M.abscessus_ATCC_1997 -------------------------------------------MKTRAAV
MMAR_3997|M.marinum_M -------------------------------------------MRSRAAI
MUL_3861|M.ulcerans_Agy99 -------------------------------------------MRSRAAI
MLBr_01784|M.leprae_Br4923 -----------------------------------------MSQTVRGVI
:
TH_4578|M.thermoresistible__bu LRGVGVDWEVTEIELDPPRAGEVLVKMAYAGICHSDEHFYTGDSVPSKEM
MAV_5214|M.avium_104 IRGVGRDWEIAEIELDPPRSGEVLVRMAVAGICHSDDHLFTGDVVPTP--
Mb3113|M.bovis_AF2122/97 LFEAGKPFELMELDLDGPGPGEVLVKYTAAGLCHSDLHLTDGD-------
Rv3086|M.tuberculosis_H37Rv LFEAGKPFELMELDLDGPGPGEVLVKYTAAGLCHSDLHLTDGD-------
MSMEG_3388|M.smegmatis_MC2_155 SLGVNRPFEIMELELDGPKEGEVLLKNVAAGLCHSDLHLTDGD-------
Mflv_1486|M.gilvum_PYR-GCK LWEYGGDWTVEEIDLDPPGDGEVLVSWQATGLCHSDEHIRTGD-------
Mvan_5270|M.vanbaalenii_PYR-1 LWEYGGDWTVEEIDLDPPGDGEVLVSWEATGLCHSDEHIRTGD-------
MAB_2084|M.abscessus_ATCC_1997 LWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGD-------
MMAR_3997|M.marinum_M LHDVGGPWSVEEFELDTPRTGEVLVEMSAAGLCHTDDHILKGDMSAPN--
MUL_3861|M.ulcerans_Agy99 LHDVGEPWSVEEFELDAPRTAEVLVEMSAAGLCHTDDHILKGDMSAPN--
MLBr_01784|M.leprae_Br4923 SRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCHTDLTYREGG-------
: :. : * .*.:: *:**:* *.
TH_4578|M.thermoresistible__bu EEMMRASGVPVPEWFPMLGGHEGAGVVEDVGPEVRTLKPGDHVAVSFLPA
MAV_5214|M.avium_104 -EVVAASGQPAPDWFPLLGGHEGAGVVAEVGPNVTSVRPGDHVALSFIPA
Mb3113|M.bovis_AF2122/97 ----------LPPRFPIVGGHEGSGVIEEVGAGVTRVKPGDHVVCSFIPN
Rv3086|M.tuberculosis_H37Rv ----------LPPRFPIVGGHEGSGVIEEVGAGVTRVKPGDHVVCSFIPN
MSMEG_3388|M.smegmatis_MC2_155 ----------MPPRYPIVGGHEGSAIVEDVGPGVTKVKPGDHVVCSYIPN
Mflv_1486|M.gilvum_PYR-GCK ----------LPAPLPLIGGHEGAGIVREVGAGVVGLAPGDHVVASFLPA
Mvan_5270|M.vanbaalenii_PYR-1 ----------LPAPLPLIGGHEGAGIVREVGPGVVGLAPGDHVVASFLPA
MAB_2084|M.abscessus_ATCC_1997 ----------LPIPLPVVGGHEGAGTVVECGEGVEDLSEGDSVILTFLPS
MMAR_3997|M.marinum_M ---EVLRSRGLPTMFPTIGGHEGSGIVREIGPGVTDFAPGDHVVMSFIAV
MUL_3861|M.ulcerans_Agy99 ---EVLRSRGLPTMFPTIGGHEGSGIVREIGPGVTDFVPGDHVVMSFVAV
MLBr_01784|M.leprae_Br4923 ----------INDRYPFLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAV
* : ***.:. : * * . ** * .: .
TH_4578|M.thermoresistible__bu CGSCRWCASGHTYLCDVGADLYSKRMTTDGTARRHLPDPDGDRDLMAMMQ
MAV_5214|M.avium_104 CGSCRFCVNGQSYICDVGASLFVREMPTDGTCRRHL----GAENLLAYGQ
Mb3113|M.bovis_AF2122/97 CGTCRYCCTGRQNLCDMGATILEGCMP-DGSFRFHS----QGTDFGAMCM
Rv3086|M.tuberculosis_H37Rv CGTCRYCCTGRQNLCDMGATILEGCMP-DGSFRFHS----QGTDFGAMCM
MSMEG_3388|M.smegmatis_MC2_155 CGTCRYCATGRSNLCDMGATILDGRFP-DGTFRFHK----DGVDYGSLCL
Mflv_1486|M.gilvum_PYR-GCK CGRCRFCSTGHQNLCDLGAMIMAGTQL-DGTYRRHI----NGQDVGVMAL
Mvan_5270|M.vanbaalenii_PYR-1 CGRCRFCSTGHQNLCDLGAMIMAGTQL-DGTYRRHV----RGQDVGVMAL
MAB_2084|M.abscessus_ATCC_1997 CGRCSYCARGMGNLCELGAALMMGPQI-DGTYRFHA----RGEDVGQMCL
MMAR_3997|M.marinum_M CGQCRWCASGMEYLCDAGIGTLTPGMPTDGTFRHHT---ADGTPLGHLAK
MUL_3861|M.ulcerans_Agy99 CGQCRWCASGMEYLCDAGIGTLTPGMPTDGTFRHHT---ADGTPLGHLAK
MLBr_01784|M.leprae_Br4923 CGQCRACKRGRPSYCFDTFNAQQKMTLIDGTELTPALG------------
** * * * * **:
TH_4578|M.thermoresistible__bu VGTFAEYVVASERSLVKVHDWIPLAAASLVSCGVTTGFGSGSVAAGTQPG
MAV_5214|M.avium_104 LGTFAEYAVLSERSVIKIDEAIPFHAASLVSCGVSTGWGSATVSAGTEPG
Mb3113|M.bovis_AF2122/97 LGTFAERATVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTAVNAGNLRAG
Rv3086|M.tuberculosis_H37Rv LGTFAERATVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTAVNAGNLRAG
MSMEG_3388|M.smegmatis_MC2_155 LGSFAERTTVSQHSVVKVDEWIPLETAVLVGCGVPAGWGGPVYNNGIRPG
Mflv_1486|M.gilvum_PYR-GCK VGTFSQYGTVPEASIVKIDDDIPLSRACLLGCGVTTGWGSAVNTADVSPG
Mvan_5270|M.vanbaalenii_PYR-1 VGTFSQYGTVPEASIVKIDDDIPLSRACLLGCGVTTGWGSAVNTADVSPG
MAB_2084|M.abscessus_ATCC_1997 LGTFSEYTVVPQASVVKIDGGIPLDRAALIGCGVTTGYGSAVRTGEVRAG
MMAR_3997|M.marinum_M VGAFAEHTVVSRDSLVKIDPDLPLAPSALLSCAIPTGYGSAANRAGVRGG
MUL_3861|M.ulcerans_Agy99 VGAFAEHTVVSRDSLVKIDPDLPLAPSALLSCAIPTGYGSAANRAGVRGG
MLBr_01784|M.leprae_Br4923 IGAFADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAINTAAVSRD
:*:*:: . *:. : *:.*.: :* * .
TH_4578|M.thermoresistible__bu DTVVVVGVGGIGMNAVQGARTAGAKHIVAVDPVEFKREIAPTFGATHAVA
MAV_5214|M.avium_104 DTVVVIGAGGVGMNALQGARAVGAKYVVAVDPIAAKRDSAKIFGATHTAA
Mb3113|M.bovis_AF2122/97 DTAVIYGVGGLGINAVQGATAAGCKYVVVVDPVAFKRETALKFGATHAFA
Rv3086|M.tuberculosis_H37Rv DTAVIYGVGGLGINAVQGATAAGCKYVVVVDPVAFKRETALKFGATHAFA
MSMEG_3388|M.smegmatis_MC2_155 DTAVIYGIGGLGINAIQGAVMAGARYVVAVDPVEFKRDMALKFGATHAFA
Mflv_1486|M.gilvum_PYR-GCK DTVVIIGLGGIGSGAIQGARLAGAEKIVVVEPVETKRDLAFRFGATHFVT
Mvan_5270|M.vanbaalenii_PYR-1 DTVVIIGLGGIGSGAIQGARLAGAEKIVVIEPVESKRELAFRFGATHFVT
MAB_2084|M.abscessus_ATCC_1997 DTVVVVGAGGIGMNAIQGARIAGALAIVAVDPVNFKREQASGFGATHTAA
MMAR_3997|M.marinum_M DTVVVLGAGGIGTGAIQGARINGAAQIVAVDPVEFKQKSAHLFGATHGAG
MUL_3861|M.ulcerans_Agy99 DTVVVLGAGGIGTGAIQGARINGAAQIVAIDPVEFKQKSAYLFGATHGAG
MLBr_01784|M.leprae_Br4923 DTVAVIGCGGVGDAAISGAALVGANRIIAVDIDDTKLEWARTFGATHTVN
**..: * **:* *:.** *. ::.:: * . * *****
TH_4578|M.thermoresistible__bu DIG-AALDLVKDITWGVMADRVVLTPGVVPPDMVMAAMMLLRKGGTCVLT
MAV_5214|M.avium_104 SAR-DAIPLVREITAGLMADRVVVCPGVVHVDSIPLALALLRKGGVCVLT
Mb3113|M.bovis_AF2122/97 DAA-SAAAKVDELTWGQGADAALILVGTVDDEVVSAATAVIGKGGTVVIT
Rv3086|M.tuberculosis_H37Rv DAA-SAAAKVDELTWGQGADAALILVGTVDDEVVSAATAVIGKGGTVVIT
MSMEG_3388|M.smegmatis_MC2_155 TAE-EAHEAVREITWGQMADGALIFVGTPDEKVVSDAFNVIGKGGTVSLA
Mflv_1486|M.gilvum_PYR-GCK SME-EATALVAELTRGVMADSAILTVGLLAGSMLEEAANIIRKGGAVVMT
Mvan_5270|M.vanbaalenii_PYR-1 SME-EATALVADLTRGVMADSAILTVGLLEGSMLEEAANIIRKGGAVVMT
MAB_2084|M.abscessus_ATCC_1997 SMD-EAWSLVSDMTRGKLADVCILTTDVAEGSYTAEALALVGKRGRVVVT
MMAR_3997|M.marinum_M SIS-EAMALVRELTHGVMADSVLVSPSLITADDVRDALRLTRKGGTCVLA
MUL_3861|M.ulcerans_Agy99 SIS-QAMALVRELTHGVMADSVLVSPSLITADDVRDALRLTCKGGTCVLA
MLBr_01784|M.leprae_Br4923 ALELEVVKTIQDLTSGFGVDVVIDTVGR--PETWKQAFYARDLAGTVVLV
. : ::* * .* : . . * * :.
TH_4578|M.thermoresistible__bu GMAKVSDLNVPLSLPDMVSSCKTLKGVLYGEMNPRDAMPKLLSMYEAGTL
MAV_5214|M.avium_104 GITPFTEPPVPLVLQEMTLSAKQLRGALYGGMNPRTSVPMLLSLYQAGDL
Mb3113|M.bovis_AF2122/97 GLADPAKLTVHVSGTDLTLHEKTIKGSLFGSCNPQYDIVRLLRLYDAGQL
Rv3086|M.tuberculosis_H37Rv GLADPAKLTVHVSGTDLTLHEKTIKGSLFGSCNPQYDIVRLLRLYDAGQL
MSMEG_3388|M.smegmatis_MC2_155 SLADPAKLTVHVSGMEMTLMEKTIKGCLFGSSNPQYDIVRLLRLYDEGKL
Mflv_1486|M.gilvum_PYR-GCK ALSTMADNQPTLGMMMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKL
Mvan_5270|M.vanbaalenii_PYR-1 ALSTMADNQPTLGMMMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKL
MAB_2084|M.abscessus_ATCC_1997 AIGHPDESSISGSLLEMTLYEKQIRGALYGSSNAPHDIPRLVELYSAGLL
MMAR_3997|M.marinum_M GMTSQLTRSVNIDLQEFILMNKTLAGTIFGSCNPRADIARLAGLYQSGQL
MUL_3861|M.ulcerans_Agy99 GMTSQLTRSVNIDLQEFILMNKTLAGTIFGSCNPRADIARLAGLYQSGQL
MLBr_01784|M.leprae_Br4923 GVPTP-DMRLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVDLYLQGRL
.: : : . :* . . * :* * *
TH_4578|M.thermoresistible__bu KLDELITNRYKLDDINEAMRDLRAGKNIRGVIAFD---
MAV_5214|M.avium_104 KLDELVTRHYRLDEINEAFADLREGRNIRGVIDFAGR-
Mb3113|M.bovis_AF2122/97 MLDELVTTTYNLEQVNQGYQDLRDGKNIRGVIVH----
Rv3086|M.tuberculosis_H37Rv MLDELVTTTYNLEQVNQGYQDLRDGKNIRGVIVH----
MSMEG_3388|M.smegmatis_MC2_155 KLDELITTRYRLEDINQGYDDLRAGVNIRGVIIHDPEA
Mflv_1486|M.gilvum_PYR-GCK LLDETVTHEYKLAEVNEGYEDMREGRNIRGVILHDH--
Mvan_5270|M.vanbaalenii_PYR-1 LLDETVTHEYKLAEVNEGYEDMRAGRNIRGVILHDH--
MAB_2084|M.abscessus_ATCC_1997 KLDELVTREYSLDQINEGYQDMRSGRNIRGLVRF----
MMAR_3997|M.marinum_M QLDDMITRRYRLDDINAAYTDLLNGDIVRGIIDFTI--
MUL_3861|M.ulcerans_Agy99 QLDEMITRRYRLDDINAAYTDLLNGDIVRGIIDFTI--
MLBr_01784|M.leprae_Br4923 PLGKFVSERIGLGDVEEAFHKIHGGKVLRSVVML----
*.. :: * ::: . .: * :*.::