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M. thermoresistible (build 8) TH_2786 (-)

annotation: Alcohol dehydrogenase GroES domain protein
coordinates: 45406 - 46527
length: 374

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2786 - - 100% (374) Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8) TH_2499 - e-149 68.45% (374) PUTATIVE Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8) TH_1254 - e-108 52.16% (370) alcohol dehydrogenase B

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0784c adhB 1e-105 49.46% (370) zinc-containing alcohol dehydrogenase NAD dependant ADHB
M. gilvum PYR-GCK Mflv_1486 - 1e-158 70.24% (373) alcohol dehydrogenase
M. tuberculosis H37Rv Rv0761c adhB 1e-105 49.46% (370) zinc-containing alcohol dehydrogenase NAD dependent ADHB
M. leprae Br4923 MLBr_01784 adhE2 1e-47 33.43% (359) putative alcohol dehydrogenase (Zn dependent)
M. abscessus ATCC 19977 MAB_2084 - 1e-112 55.01% (369) zinc-type alcohol dehydrogenase AdhD
M. marinum M MMAR_3150 - 1e-110 52.57% (369) zinc-containing alcohol dehydrogenase NAD- dependent
M. avium 104 MAV_0705 - 1e-104 50.54% (370) alcohol dehydrogenase B
M. smegmatis MC2 155 MSMEG_5866 - 1e-106 51.62% (370) alcohol dehydrogenase B
M. ulcerans Agy99 MUL_0470 adhB 1e-101 48.92% (370) zinc-containing alcohol dehydrogenase NAD- dependent AdhB
M. vanbaalenii PYR-1 Mvan_5270 - 1e-159 71.31% (373) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1486|M.gilvum_PYR-GCK          --MKTNAAILWEYGGDWTVEEIDLDPPGDGEVLVSWQATGLCHSDEHIRT
Mvan_5270|M.vanbaalenii_PYR-1       --MKTNAAILWEYGGDWTVEEIDLDPPGDGEVLVSWEATGLCHSDEHIRT
TH_2786|M.thermoresistible__bu      --VKTKAAVLFEFGAPWSIEEVDLDPPAEGEVLVAWEASGLCHSDEHLRL
MAB_2084|M.abscessus_ATCC_1997      --MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVT
MMAR_3150|M.marinum_M               --MKTRAAVLWGLGEKWEVEDIELDPPGPDEVLVQLTATGLCHSDEHLVT
Mb0784c|M.bovis_AF2122/97           --MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCRSDHHLVT
Rv0761c|M.tuberculosis_H37Rv        --MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCRSDHHLVT
MUL_0470|M.ulcerans_Agy99           --MKTKGALIWEFNQPWSVEDIEIGDPVKDEVKIQMEAAGMCRSDNHLVT
MAV_0705|M.avium_104                --MKTKGALIWEFNQPWSIEEIEIGDPQAHEVKIQMEAAGMCHSDHHLVT
MSMEG_5866|M.smegmatis_MC2_155      --MKTKGALIWEFNQPWSIEEIEIGDPVKDEVKIQMEASGMCHSDHHLVT
MLBr_01784|M.leprae_Br4923          MSQTVRGVISRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCHTDLTYRE
                                       .....:         : :: :  *   *. :   * *:*::*     

Mflv_1486|M.gilvum_PYR-GCK          GDLP-APLP---LIGGHEGAGIVREVGAGVVGLAPGDHVVASFLPACGRC
Mvan_5270|M.vanbaalenii_PYR-1       GDLP-APLP---LIGGHEGAGIVREVGPGVVGLAPGDHVVASFLPACGRC
TH_2786|M.thermoresistible__bu      GDFG-GPIPEVAMIGGHEGAGRIVEVGPGVRGLKEGDHVVASFIPACGRC
MAB_2084|M.abscessus_ATCC_1997      GDLP-IPLP---VVGGHEGAGTVVECGEGVEDLSEGDSVILTFLPSCGRC
MMAR_3150|M.marinum_M               GDLP-IPLP---VVGGHEGAGTVVEVGAGVENVAEGDSVILTFLPSCGHC
Mb0784c|M.bovis_AF2122/97           GDIPMAGFP---VLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPSCGKC
Rv0761c|M.tuberculosis_H37Rv        GDIPMAGFP---VLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPSCGKC
MUL_0470|M.ulcerans_Agy99           GGIPMAGFP---VLGGHEGAGVVTEVGPGVDDIAPGDHVVLSFIPSCGRC
MAV_0705|M.avium_104                GGIPMAGFP---VLGGHEGAGIVTEVGPGVEDIAPGDHVVLSFIPSCGSC
MSMEG_5866|M.smegmatis_MC2_155      GGIPMGGFP---VLGGHEGAGIVTEVGPGVEGIEPGDHVVLSFIPSCGSC
MLBr_01784|M.leprae_Br4923          GGIN-DRYP---FLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAVCGQC
                                    *.:     *   .: ***.** :   * **  .  ** *:  : . ** *

Mflv_1486|M.gilvum_PYR-GCK          RFCSTGHQNLCDLGAMIMAGTQL-DGTYRRHINGQDVGVMALVGTFSQYG
Mvan_5270|M.vanbaalenii_PYR-1       RFCSTGHQNLCDLGAMIMAGTQL-DGTYRRHVRGQDVGVMALVGTFSQYG
TH_2786|M.thermoresistible__bu      RFCATGQSNLCDLGALLMTGTQP-DGTFRRRVNSKNVGAMSFVGSFSQYG
MAB_2084|M.abscessus_ATCC_1997      SYCARGMGNLCELGAALMMGPQI-DGTYRFHARGEDVGQMCLLGTFSEYT
MMAR_3150|M.marinum_M               SYCARGMGNMCDLGAALMMGPQI-DGTYRFHARGEDVGQMCLLGTFSEYT
Mb0784c|M.bovis_AF2122/97           PSCQAGMRNLCDLGAGLLAGESVTDGSFRIQARGQNVYPMTLLGTFSPYM
Rv0761c|M.tuberculosis_H37Rv        PSCQAGMRNLCDLGAGLLAGESVTDGSFRIQARGQNVYPMTLLGTFSPYM
MUL_0470|M.ulcerans_Agy99           PTCQAGLRNLCDLGAGLLAGAAVSDGTFRIQARGQNVYPMTLLGTFSPYM
MAV_0705|M.avium_104                PTCQAGMRNLCDLGAGLLGGEAVSDGTFRIQARGQNVYPMTLLGTFSPYM
MSMEG_5866|M.smegmatis_MC2_155      PSCQAGLRNLCDLGAGLLGGVAVADGTHRIHANGKPVFPMTLLGTFSPYM
MLBr_01784|M.leprae_Br4923          RACKRGRPSYCFDTFNAQQKMTLIDGTELTPALG--------IGAFADKT
                                      *  *  . *             **:      .        :*:*:   

Mflv_1486|M.gilvum_PYR-GCK          TVPEASIVKIDDDIPLSRACLLGCGVTTGWGSAVNTADVSPGDTVVIIGL
Mvan_5270|M.vanbaalenii_PYR-1       TVPEASIVKIDDDIPLSRACLLGCGVTTGWGSAVNTADVSPGDTVVIIGL
TH_2786|M.thermoresistible__bu      SIPEASVVKIDDDIPLARACLLGCGITTGWGSAVNTAAVEPGDTVVVWGC
MAB_2084|M.abscessus_ATCC_1997      VVPQASVVKIDGGIPLDRAALIGCGVTTGYGSAVRTGEVRAGDTVVVVGA
MMAR_3150|M.marinum_M               VVPKASLVKIDQGTPLDKAALIGCGVTTGYGSAVRTGEVRAGDTVAVIGA
Mb0784c|M.bovis_AF2122/97           VVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDVAIVGL
Rv0761c|M.tuberculosis_H37Rv        VVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDVAIVGL
MUL_0470|M.ulcerans_Agy99           VVHRSSVVKIDPAIPFEVAALVGCGVTTGYGSAVRTADVRPGDDVAIVGL
MAV_0705|M.avium_104                VVHRSSVVKIDPSIPFEVAALVGCGVTTGYGSAVRTADIRPGQDVAIVGV
MSMEG_5866|M.smegmatis_MC2_155      VVHKSSVVKIDKSIPFEVACLVGCGVTTGYGSAVRSGDIRPGDDVAIFGI
MLBr_01784|M.leprae_Br4923          LVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAINTAAVSRDDTVAVIGC
                                     :  .. .*:*       * *:***: :* *:*:.:. :  .: *.: * 

Mflv_1486|M.gilvum_PYR-GCK          GGIGSGAIQGARLAGAEKIVVVEPVETKRDLAFRFGATHFVTSMEEATAL
Mvan_5270|M.vanbaalenii_PYR-1       GGIGSGAIQGARLAGAEKIVVIEPVESKRELAFRFGATHFVTSMEEATAL
TH_2786|M.thermoresistible__bu      GGIGSGAIQGARVAGAEHIVAIDLVESKREKAMQFGATHFVTSVEEATAL
MAB_2084|M.abscessus_ATCC_1997      GGIGMNAIQGARIAGALAIVAVDPVNFKREQASGFGATHTAASMDEAWSL
MMAR_3150|M.marinum_M               GGIGMNAIQGARIAGALNIVAVDPVAFKREQAGGFGATHAVATIDEAWSL
Mb0784c|M.bovis_AF2122/97           GGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDINAALMG
Rv0761c|M.tuberculosis_H37Rv        GGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDINAALMG
MUL_0470|M.ulcerans_Agy99           GGVGMAALQGAVTAGARYIFAVEPVEWKRDQALKFGATHVYPDMEAALMG
MAV_0705|M.avium_104                GGVGMAALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDIMAAMAG
MSMEG_5866|M.smegmatis_MC2_155      GGVGMGALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDVFSAMAG
MLBr_01784|M.leprae_Br4923          GGVGDAAISGAALVGANRIIAVDIDDTKLEWARTFGATHTVNALELEVVK
                                    **:*  *:.**  .**  :..::    * : *  *****    :      

Mflv_1486|M.gilvum_PYR-GCK          -VAELTRGVMADSAILTVGLLAGSMLEEAANIIRKGGAVVMTALSTMADN
Mvan_5270|M.vanbaalenii_PYR-1       -VADLTRGVMADSAILTVGLLEGSMLEEAANIIRKGGAVVMTALSTMADN
TH_2786|M.thermoresistible__bu      -VAELTRGVMADSVILTVGVLRGTMIEEGLNMTRKGGAVVMTAIAPITDQ
MAB_2084|M.abscessus_ATCC_1997      -VSDMTRGKLADVCILTTDVAEGSYTAEALALVGKRGRVVVTAIGHPDES
MMAR_3150|M.marinum_M               -ISDITRGKLADVCVLTTDVAEGSYIGEALSLVGKRGRVVVTAIGHPEDT
Mb0784c|M.bovis_AF2122/97           -IAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIGSLVDT
Rv0761c|M.tuberculosis_H37Rv        -IAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIGSLVDT
MUL_0470|M.ulcerans_Agy99           -IAEVTYGLMAKKVMITVGELQGSDIDTYLAITSKGGTCVVTAIGSLLDT
MAV_0705|M.avium_104                -MAEVTYGLMAHKVVVTVGELQGADVDNYLNITQKGGTCVLTAIGSLLDT
MSMEG_5866|M.smegmatis_MC2_155      -IAEVTAGGMAKKVIVTVGELHGEDIDNYLNVTSKGGTCVVTAVGSMLDT
MLBr_01784|M.leprae_Br4923          TIQDLTSGFGVDVVIDTVGRPE--TWKQAFYARDLAGTVVLVGVPTP-DM
                                     : ::* *  ..  : *..                 *  *:..:    : 

Mflv_1486|M.gilvum_PYR-GCK          QPTLGMMMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKLLLDETVTH
Mvan_5270|M.vanbaalenii_PYR-1       QPTLGMMMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKLLLDETVTH
TH_2786|M.thermoresistible__bu      AVTMSMGAATLFQKRVLGSLYGEANPRADIPRLLRLYRNGQLLLDEVVTA
MAB_2084|M.abscessus_ATCC_1997      SISGSLLEMTLYEKQIRGALYGSSNAPHDIPRLVELYSAGLLKLDELVTR
MMAR_3150|M.marinum_M               SMSGSLLELTLYEKQIRGALYGSSNAAHDIPRLVELYNAGHLKLDELITR
Mb0784c|M.bovis_AF2122/97           QVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLDDMVTT
Rv0761c|M.tuberculosis_H37Rv        QVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLDDMVTT
MUL_0470|M.ulcerans_Agy99           QVNLNLAMLTLMQKNLQGTIFGGGNPQYDIPHLLSMYKARNLNIDDMITR
MAV_0705|M.avium_104                NVTLNLAMLTLMQKNLQGTIFGGGNPQYDIPQLLSMYKAGKLNLDDMITR
MSMEG_5866|M.smegmatis_MC2_155      NANINLAMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGKLNLDDMVTR
MLBr_01784|M.leprae_Br4923          RLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVDLYLQGRLPLGKFVSE
                                         :         : .: :*   .  *:* *: :*    * :.. :: 

Mflv_1486|M.gilvum_PYR-GCK          EYKLAEVNEGYEDMREGRNIRGVILHDH---
Mvan_5270|M.vanbaalenii_PYR-1       EYKLAEVNEGYEDMRAGRNIRGVILHDH---
TH_2786|M.thermoresistible__bu      EYKLEDITAGYDDMLSGRNIRGVMVHQH---
MAB_2084|M.abscessus_ATCC_1997      EYSLDQINEGYQDMRSGRNIRGLVRF-----
MMAR_3150|M.marinum_M               EYTLDQINEGYADMRSGRNIRGLIRF-----
Mb0784c|M.bovis_AF2122/97           AYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
Rv0761c|M.tuberculosis_H37Rv        AYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
MUL_0470|M.ulcerans_Agy99           QYRLEQINEGYQDMIDGKNIRGVIRFTDADR
MAV_0705|M.avium_104                QYRLEQINDGYQDMLDGKNIRGVIRYTDADR
MSMEG_5866|M.smegmatis_MC2_155      QYRLEQINDGYQDMLEGRNIRGVIRYTDADR
MLBr_01784|M.leprae_Br4923          RIGLGDVEEAFHKIHGGKVLRSVVML-----
                                       * ::  .: .:  *: :*.::

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2786	-	-	100% (374)	Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8)	TH_2499	-	e-149	68.45% (374)	PUTATIVE Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8)	TH_1254	-	e-108	52.16% (370)	alcohol dehydrogenase B