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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2499 | - | - | 100% (373) | Alcohol dehydrogenase GroES domain protein |
| M. thermoresistible (build 8) | TH_2786 | - | e-149 | 68.45% (374) | PUTATIVE Alcohol dehydrogenase GroES domain protein |
| M. thermoresistible (build 8) | TH_1254 | - | e-107 | 52.57% (369) | alcohol dehydrogenase B |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3113 | adhD | 1e-107 | 52.03% (369) | zinc-type alcohol dehydrogenase AdhD |
| M. gilvum PYR-GCK | Mflv_1486 | - | 1e-169 | 76.28% (371) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3086 | adhD | 1e-107 | 52.03% (369) | zinc-type alcohol dehydrogenase AdhD |
| M. leprae Br4923 | MLBr_01784 | adhE2 | 1e-54 | 35.90% (351) | putative alcohol dehydrogenase (Zn dependent) |
| M. abscessus ATCC 19977 | MAB_2084 | - | 1e-113 | 55.59% (367) | zinc-type alcohol dehydrogenase AdhD |
| M. marinum M | MMAR_3150 | - | 1e-113 | 54.77% (367) | zinc-containing alcohol dehydrogenase NAD- dependent |
| M. avium 104 | MAV_0705 | - | 1e-106 | 51.76% (369) | alcohol dehydrogenase B |
| M. smegmatis MC2 155 | MSMEG_3388 | - | 1e-106 | 52.16% (370) | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol |
| M. ulcerans Agy99 | MUL_3861 | adhB_1 | 1e-102 | 48.42% (380) | zinc-containing alcohol dehydrogenase NAD dependent AdhB_1 |
| M. vanbaalenii PYR-1 | Mvan_5270 | - | 1e-171 | 77.09% (371) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3113|M.bovis_AF2122/97 -------------------------------------------MKTTAAV
Rv3086|M.tuberculosis_H37Rv -------------------------------------------MKTTAAV
MSMEG_3388|M.smegmatis_MC2_155 MHSDPSHIDLLGPATFTSRDRRPIGFPPLRCSRHKISWKEPSEMKTKAAV
Mflv_1486|M.gilvum_PYR-GCK -------------------------------------------MKTNAAI
Mvan_5270|M.vanbaalenii_PYR-1 -------------------------------------------MKTNAAI
TH_2499|M.thermoresistible__bu -------------------------------------------MKMNAAV
MAB_2084|M.abscessus_ATCC_1997 -------------------------------------------MKTRAAV
MMAR_3150|M.marinum_M -------------------------------------------MKTRAAV
MAV_0705|M.avium_104 -------------------------------------------MKTKGAL
MUL_3861|M.ulcerans_Agy99 -------------------------------------------MRSRAAI
MLBr_01784|M.leprae_Br4923 -----------------------------------------MSQTVRGVI
..:
Mb3113|M.bovis_AF2122/97 LFEAGKPFELMELDLDGPGPGEVLVKYTAAGLCHSDLHLTDGDLPPR---
Rv3086|M.tuberculosis_H37Rv LFEAGKPFELMELDLDGPGPGEVLVKYTAAGLCHSDLHLTDGDLPPR---
MSMEG_3388|M.smegmatis_MC2_155 SLGVNRPFEIMELELDGPKEGEVLLKNVAAGLCHSDLHLTDGDMPPR---
Mflv_1486|M.gilvum_PYR-GCK LWEYGGDWTVEEIDLDPPGDGEVLVSWQATGLCHSDEHIRTGDLPAP---
Mvan_5270|M.vanbaalenii_PYR-1 LWEYGGDWTVEEIDLDPPGDGEVLVSWEATGLCHSDEHIRTGDLPAP---
TH_2499|M.thermoresistible__bu LWDVNGDWSIEEVELDGPQEGEVLVSFTATGMCHSDHHVRTGDFPAP---
MAB_2084|M.abscessus_ATCC_1997 LWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGDLPIP---
MMAR_3150|M.marinum_M LWGLGEKWEVEDIELDPPGPDEVLVQLTATGLCHSDEHLVTGDLPIP---
MAV_0705|M.avium_104 IWEFNQPWSIEEIEIGDPQAHEVKIQMEAAGMCHSDHHLVTGGIPMAG--
MUL_3861|M.ulcerans_Agy99 LHDVGEPWSVEEFELDAPRTAEVLVEMSAAGLCHTDDHILKGDMSAPNEV
MLBr_01784|M.leprae_Br4923 SRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCHTDLTYREGGINDR---
: :. : * *. : * *:**:* *.:
Mb3113|M.bovis_AF2122/97 ---------FPIVGGHEGSGVIEEVGAGVTRVKPGDHVVCSFIPNCGTCR
Rv3086|M.tuberculosis_H37Rv ---------FPIVGGHEGSGVIEEVGAGVTRVKPGDHVVCSFIPNCGTCR
MSMEG_3388|M.smegmatis_MC2_155 ---------YPIVGGHEGSAIVEDVGPGVTKVKPGDHVVCSYIPNCGTCR
Mflv_1486|M.gilvum_PYR-GCK ---------LPLIGGHEGAGIVREVGAGVVGLAPGDHVVASFLPACGRCR
Mvan_5270|M.vanbaalenii_PYR-1 ---------LPLIGGHEGAGIVREVGPGVVGLAPGDHVVASFLPACGRCR
TH_2499|M.thermoresistible__bu ---------LPIIGGHEGAGVVQEVGPGVRDLKPGDHVVASFLPACGRCR
MAB_2084|M.abscessus_ATCC_1997 ---------LPVVGGHEGAGTVVECGEGVEDLSEGDSVILTFLPSCGRCS
MMAR_3150|M.marinum_M ---------LPVVGGHEGAGTVVEVGAGVENVAEGDSVILTFLPSCGHCS
MAV_0705|M.avium_104 ---------FPVLGGHEGAGIVTEVGPGVEDIAPGDHVVLSFIPSCGSCP
MUL_3861|M.ulcerans_Agy99 LRSRGLPTMFPTIGGHEGSGIVREIGPGVTDFVPGDHVVMSFVAVCGQCR
MLBr_01784|M.leprae_Br4923 ---------YPFLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAVCGQCR
* : ***.:. : * ** . ** *: .: . ** *
Mb3113|M.bovis_AF2122/97 YCCTGRQNLCDMGATILEGCMP-DGSFRFHSQ-GTDFGAMCMLGTFAERA
Rv3086|M.tuberculosis_H37Rv YCCTGRQNLCDMGATILEGCMP-DGSFRFHSQ-GTDFGAMCMLGTFAERA
MSMEG_3388|M.smegmatis_MC2_155 YCATGRSNLCDMGATILDGRFP-DGTFRFHKD-GVDYGSLCLLGSFAERT
Mflv_1486|M.gilvum_PYR-GCK FCSTGHQNLCDLGAMIMAGTQL-DGTYRRHIN-GQDVGVMALVGTFSQYG
Mvan_5270|M.vanbaalenii_PYR-1 FCSTGHQNLCDLGAMIMAGTQL-DGTYRRHVR-GQDVGVMALVGTFSQYG
TH_2499|M.thermoresistible__bu WCATGRSNLCDLGAMLLAGTQL-DGTYRRHLPDGRDVGVALLLGTFAQYG
MAB_2084|M.abscessus_ATCC_1997 YCARGMGNLCELGAALMMGPQI-DGTYRFHAR-GEDVGQMCLLGTFSEYT
MMAR_3150|M.marinum_M YCARGMGNMCDLGAALMMGPQI-DGTYRFHAR-GEDVGQMCLLGTFSEYT
MAV_0705|M.avium_104 TCQAGMRNLCDLGAGLLGGEAVSDGTFRIQAR-GQNVYPMTLLGTFSPYM
MUL_3861|M.ulcerans_Agy99 WCASGMEYLCDAGIGTLTPGMPTDGTFRHHTADGTPLGHLAKVGAFAEHT
MLBr_01784|M.leprae_Br4923 ACKRGRPSYCFD---------TFNAQQKMTLIDGTELTPALGIGAFADKT
* * * :. : * :*:*:
Mb3113|M.bovis_AF2122/97 TVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTAVNAGNLRAGDTAVIYGV
Rv3086|M.tuberculosis_H37Rv TVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTAVNAGNLRAGDTAVIYGV
MSMEG_3388|M.smegmatis_MC2_155 TVSQHSVVKVDEWIPLETAVLVGCGVPAGWGGPVYNNGIRPGDTAVIYGI
Mflv_1486|M.gilvum_PYR-GCK TVPEASIVKIDDDIPLSRACLLGCGVTTGWGSAVNTADVSPGDTVVIIGL
Mvan_5270|M.vanbaalenii_PYR-1 TVPEASIVKIDDDIPLSRACLLGCGVTTGWGSAVNTADVSPGDTVVIIGL
TH_2499|M.thermoresistible__bu VVSEASLVKIDDDLPLTRACLIGCGVTTGWGSAVNTAKVQPGDTVVVIGF
MAB_2084|M.abscessus_ATCC_1997 VVPQASVVKIDGGIPLDRAALIGCGVTTGYGSAVRTGEVRAGDTVVVVGA
MMAR_3150|M.marinum_M VVPKASLVKIDQGTPLDKAALIGCGVTTGYGSAVRTGEVRAGDTVAVIGA
MAV_0705|M.avium_104 VVHRSSVVKIDPSIPFEVAALVGCGVTTGYGSAVRTADIRPGQDVAIVGV
MUL_3861|M.ulcerans_Agy99 VVSRDSLVKIDPDLPLAPSALLSCAIPTGYGSAANRAGVRGGDTVVVLGA
MLBr_01784|M.leprae_Br4923 LVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAINTAAVSRDDTVAVIGC
* . .*:* : *:.*.: :* * . : .: ..: *
Mb3113|M.bovis_AF2122/97 GGLGINAVQGATAAGCKYVVVVDPVAFKRETALKFGATHAFADAA-SAAA
Rv3086|M.tuberculosis_H37Rv GGLGINAVQGATAAGCKYVVVVDPVAFKRETALKFGATHAFADAA-SAAA
MSMEG_3388|M.smegmatis_MC2_155 GGLGINAIQGAVMAGARYVVAVDPVEFKRDMALKFGATHAFATAE-EAHE
Mflv_1486|M.gilvum_PYR-GCK GGIGSGAIQGARLAGAEKIVVVEPVETKRDLAFRFGATHFVTSME-EATA
Mvan_5270|M.vanbaalenii_PYR-1 GGIGSGAIQGARLAGAEKIVVIEPVESKRELAFRFGATHFVTSME-EATA
TH_2499|M.thermoresistible__bu GGVGSGAVQGARLAGAEKIVVVDIVEDKRAKALEFGATHFVTSMA-EATA
MAB_2084|M.abscessus_ATCC_1997 GGIGMNAIQGARIAGALAIVAVDPVNFKREQASGFGATHTAASMD-EAWS
MMAR_3150|M.marinum_M GGIGMNAIQGARIAGALNIVAVDPVAFKREQAGGFGATHAVATID-EAWS
MAV_0705|M.avium_104 GGVGMAALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDIM-AAMA
MUL_3861|M.ulcerans_Agy99 GGIGTGAIQGARINGAAQIVAIDPVEFKQKSAYLFGATHGAGSIS-QAMA
MLBr_01784|M.leprae_Br4923 GGVGDAAISGAALVGANRIIAVDIDDTKLEWARTFGATHTVNALELEVVK
**:* *:.** *. :..:: * * ***** .
Mb3113|M.bovis_AF2122/97 KVDELTWGQGADAALILVGTVDDEVVSAATAVIGKGGTVVITGLADPAKL
Rv3086|M.tuberculosis_H37Rv KVDELTWGQGADAALILVGTVDDEVVSAATAVIGKGGTVVITGLADPAKL
MSMEG_3388|M.smegmatis_MC2_155 AVREITWGQMADGALIFVGTPDEKVVSDAFNVIGKGGTVSLASLADPAKL
Mflv_1486|M.gilvum_PYR-GCK LVAELTRGVMADSAILTVGLLAGSMLEEAANIIRKGGAVVMTALSTMADN
Mvan_5270|M.vanbaalenii_PYR-1 LVADLTRGVMADSAILTVGLLEGSMLEEAANIIRKGGAVVMTALSTMADN
TH_2499|M.thermoresistible__bu LVGDLTRGVMADSAILTVGLVEGPMIGECIDIIRKGGAVVLTGIAALADV
MAB_2084|M.abscessus_ATCC_1997 LVSDMTRGKLADVCILTTDVAEGSYTAEALALVGKRGRVVVTAIGHPDES
MMAR_3150|M.marinum_M LISDITRGKLADVCVLTTDVAEGSYIGEALSLVGKRGRVVVTAIGHPEDT
MAV_0705|M.avium_104 GMAEVTYGLMAHKVVVTVGELQGADVDNYLNITQKGGTCVLTAIGSLLDT
MUL_3861|M.ulcerans_Agy99 LVRELTHGVMADSVLVSPSLITADDVRDALRLTCKGGTCVLAGMTSQLTR
MLBr_01784|M.leprae_Br4923 TIQDLTSGFGVDVVIDTVGRPE--TWKQAFYARDLAGTVVLVGVPTP-DM
: ::* * .. : . * :..:
Mb3113|M.bovis_AF2122/97 TVHVSGTDLTLHEKTIKGSLFGSCNPQYDIVRLLRLYDAGQLMLDELVTT
Rv3086|M.tuberculosis_H37Rv TVHVSGTDLTLHEKTIKGSLFGSCNPQYDIVRLLRLYDAGQLMLDELVTT
MSMEG_3388|M.smegmatis_MC2_155 TVHVSGMEMTLMEKTIKGCLFGSSNPQYDIVRLLRLYDEGKLKLDELITT
Mflv_1486|M.gilvum_PYR-GCK QPTLGMMMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKLLLDETVTH
Mvan_5270|M.vanbaalenii_PYR-1 QPTLGMMMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKLLLDETVTH
TH_2499|M.thermoresistible__bu TPTLPMAMFTLFQKRLLGSLYGEANPRADIPRLLSLYREGKLLLDETVTH
MAB_2084|M.abscessus_ATCC_1997 SISGSLLEMTLYEKQIRGALYGSSNAPHDIPRLVELYSAGLLKLDELVTR
MMAR_3150|M.marinum_M SMSGSLLELTLYEKQIRGALYGSSNAAHDIPRLVELYNAGHLKLDELITR
MAV_0705|M.avium_104 NVTLNLAMLTLMQKNLQGTIFGGGNPQYDIPQLLSMYKAGKLNLDDMITR
MUL_3861|M.ulcerans_Agy99 SVNIDLQEFILMNKTLAGTIFGSCNPRADIARLAGLYQSGQLQLDEMITR
MLBr_01784|M.leprae_Br4923 RLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVDLYLQGRLPLGKFVSE
: : . :* . *: * :* * * *.. ::
Mb3113|M.bovis_AF2122/97 TYNLEQVNQGYQDLRDGKNIRGVIVH-----
Rv3086|M.tuberculosis_H37Rv TYNLEQVNQGYQDLRDGKNIRGVIVH-----
MSMEG_3388|M.smegmatis_MC2_155 RYRLEDINQGYDDLRAGVNIRGVIIHDPEA-
Mflv_1486|M.gilvum_PYR-GCK EYKLAEVNEGYEDMREGRNIRGVILHDH---
Mvan_5270|M.vanbaalenii_PYR-1 EYKLAEVNEGYEDMRAGRNIRGVILHDH---
TH_2499|M.thermoresistible__bu EYKLHDINQGYDDMLAGRIIRGVIVHDHS--
MAB_2084|M.abscessus_ATCC_1997 EYSLDQINEGYQDMRSGRNIRGLVRF-----
MMAR_3150|M.marinum_M EYTLDQINEGYADMRSGRNIRGLIRF-----
MAV_0705|M.avium_104 QYRLEQINDGYQDMLDGKNIRGVIRYTDADR
MUL_3861|M.ulcerans_Agy99 RYRLDDINAAYTDLLNGDIVRGIIDFTI---
MLBr_01784|M.leprae_Br4923 RIGLGDVEEAFHKIHGGKVLRSVVML-----
* ::: .: .: * :*.::