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M. thermoresistible (build 8) TH_4549 (-)

annotation: putative TetR-family protein transcriptional regulator
coordinates: 3892625 - 3893335
length: 237

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4549--100% (237)putative TetR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_4347-1e-1026.90% (145) PUTATIVE transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_2984-2e-0735.37% (82) PUTATIVE putative transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0672c-5e-1034.69% (98) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0941-1e-2330.53% (226) TetR family transcriptional regulator
M. tuberculosis H37RvRv0653c-5e-1034.69% (98) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3875-2e-1232.67% (101) TetR family transcriptional regulator
M. marinum MMMAR_0992-6e-1033.01% (103) transcriptional regulatory protein
M. avium 104MAV_4506-3e-1237.25% (102) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_5307-3e-3943.61% (227) TetR-family protein transcriptional regulator
M. ulcerans Agy99MUL_0743-1e-0932.04% (103) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2233-1e-0932.26% (124) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_4549|M.thermoresistible__bu      -------VDGLTEQQREQRE--------------RILRAAAEILAEQGRD
MSMEG_5307|M.smegmatis_MC2_155      -------MAKATSSVLPPAE--------------RILAAAADLLRAGGID
Mb0672c|M.bovis_AF2122/97           --------------MTSQTG--------VRD---ELLHAGVRLLDDHGPD
Rv0653c|M.tuberculosis_H37Rv        --------------MTSQTG--------VRD---ELLHAGVRLLDDHGPD
MMAR_0992|M.marinum_M               -------MIGETTSPTQRSG--------VRD---EMLHAAVALLDAHGPD
MUL_0743|M.ulcerans_Agy99           -------MIGETTSPTQRSG--------VRD---EMLHAAVALLDAHGPD
MAV_4506|M.avium_104                ----------MTSQPAPQRN--------VRD---GMLAAAVALLHEHGAD
MAB_3875|M.abscessus_ATCC_1997      MNVLPLCEHGKTMSSSARRNSEGTDRAVVRNPRVDLVSAAVRLLNEQGPD
Mflv_0941|M.gilvum_PYR-GCK          --------------MDSGRR--------------RLIDAGLALLTEQADR
Mvan_2233|M.vanbaalenii_PYR-1       MPQPPPGDRGPQSADDPDSP-----------TRQRILAATAEVLGRNGTT
                                                                       :: *   :*   .  

TH_4549|M.thermoresistible__bu      AVTTRNVSAAAGVQPPTIYRHFGDMRRLIDDAASLGMAEYLKAKRERALT
MSMEG_5307|M.smegmatis_MC2_155      AVSTRAVATEAGVQPPTIYRQFGDKDGLLDAVTRHVLESYIDRKR--LLT
Mb0672c|M.bovis_AF2122/97           ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP-QT
Rv0653c|M.tuberculosis_H37Rv        ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP-QT
MMAR_0992|M.marinum_M               ALQTRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQFDTALAVP-PS
MUL_0743|M.ulcerans_Agy99           ALQTRKVAGATGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALAVP-PS
MAV_4506|M.avium_104                ALQTRKVAGAAGTSTMAVYTHFGGMRGLIAEVAEEGLRQFDAALTVP-PT
MAB_3875|M.abscessus_ATCC_1997      ALQTRKIAAAAGTSTMAVYTYFGGMRELIAEVAEAGLRQFAEAQAAVEQS
Mflv_0941|M.gilvum_PYR-GCK          EPSTRELYEAAGVAAPTLYHHFGTKEGLLEAVVTEAFSDYLERKRAVPDS
Mvan_2233|M.vanbaalenii_PYR-1       KLSLSEVASQAGVSRPTLYRYFADKRELLDVFVVWERQYYERAIAR----
                                          :   :*.   ::*  *.    *:   .      :          

TH_4549|M.thermoresistible__bu      D---DPVHDLRDGWDLHVEFGLRHPATYTVLYGDPRPD-AKPRAVAEGDA
MSMEG_5307|M.smegmatis_MC2_155      DPDADPALILRELWDLHVEFGMQQPHCYLLTYGQGR----RTSAADETVS
Mb0672c|M.bovis_AF2122/97           A---DPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGINVPARDVLTL
Rv0653c|M.tuberculosis_H37Rv        A---DPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGINVPARDVLTL
MMAR_0992|M.marinum_M               D---DPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGINAPTQNVLTL
MUL_0743|M.ulcerans_Agy99           D---DPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGINAPAQNVLTL
MAV_4506|M.avium_104                D---DPVADLFVIGAAYRRYAIKHRHMYRLMFGSTSAHGINAPAHNVLTL
MAB_3875|M.abscessus_ATCC_1997      D---DVIADFMLTGMAYRQFAIDYPHMYRLMFGVTSAHGVNAPRRNMFDT
Mflv_0941|M.gilvum_PYR-GCK          G---DLVADFAAGWDMHIEFGVQNPVLYRLMFGQAEER--RSSARDIAET
Mvan_2233|M.vanbaalenii_PYR-1       -----ATADLPVS--ERLDAALRVIVEYQLSY----------PGLRMVDV
                                             :          .:     * : :                  

TH_4549|M.thermoresistible__bu      ILRSLMQRVAEAGRLRIGVDRAAEMMHSACRGVTLT--------------
MSMEG_5307|M.smegmatis_MC2_155      ILGEVIGRLGAAGRLTMSVRRATDYFRASGTGFVMS--------------
Mb0672c|M.bovis_AF2122/97           KVAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD--------------
Rv0653c|M.tuberculosis_H37Rv        KVAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD--------------
MMAR_0992|M.marinum_M               TISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGADRNRASAPDGLATDVP
MUL_0743|M.ulcerans_Agy99           TISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGDDRNRAAAPDGLATDVL
MAV_4506|M.avium_104                TVAEIEQNYPSFAHVVRAVHRCMRAGRITAG-SADD--------------
MAB_3875|M.abscessus_ATCC_1997      --SHVTPEHPSAAYLFRCVQRAMAAGRIDGS--PED--------------
Mflv_0941|M.gilvum_PYR-GCK          ELRRRLQLLADEGLLRIDVDDAVSVTTGMAFGCVTQLIHSGG--------
Mvan_2233|M.vanbaalenii_PYR-1       EPDQVIKRLTRVLPLMRDRLQRLCTG-----------------------P
                                                  :                                   

TH_4549|M.thermoresistible__bu      --LISQTPAERDPELSAATREAMLAAITTGGAAGPADGAG-VATRAIALK
MSMEG_5307|M.smegmatis_MC2_155      --QLSLASEERDAELSGIIFEATLAAVSTDGRRGRGRKANDVRARAVALR
Mb0672c|M.bovis_AF2122/97           DTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVALG
Rv0653c|M.tuberculosis_H37Rv        DTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVALG
MMAR_0992|M.marinum_M               DAEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALG
MUL_0743|M.ulcerans_Agy99           DAEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALG
MAV_4506|M.avium_104                DGAVVATAAQFWASIHGFVMLELAGYCGDDGSAVLPVLGSMTSNLLVALG
MAB_3875|M.abscessus_ATCC_1997      AAKVAATAAKFWTVMHGFVMLELAGFWGEDGAAVGPVLASMTTDLLVALG
Mflv_0941|M.gilvum_PYR-GCK          DATSAVAQAIRHALITELTGSPVRHDDPAQAARQVLAGLGTMPALFTPAE
Mvan_2233|M.vanbaalenii_PYR-1       DAALAAATAVRVAISQYLVRSDDSEQFLAQLRHAARVKHRDM--------
                                          :     .                                     

TH_4549|M.thermoresistible__bu      SVLETGGAGVLTEAEAELLKEWLDRLSQ--
MSMEG_5307|M.smegmatis_MC2_155      EALPESRTPALSAAEQGLLAEWLDRLADQA
Mb0672c|M.bovis_AF2122/97           DSPERAQCSLRAEQTQKNTLGRAT------
Rv0653c|M.tuberculosis_H37Rv        DSPERAQCSLRAEQTQKNTLGRAT------
MMAR_0992|M.marinum_M               DSPE------LAKRSQRLATGAG-------
MUL_0743|M.ulcerans_Agy99           DSPE------LAKRSQRLTTGAG-------
MAV_4506|M.avium_104                DSPK------RVSQSMRSAMLGS-------
MAB_3875|M.abscessus_ATCC_1997      DTPERLN-SSAAAAAARLAPSA--------
Mflv_0941|M.gilvum_PYR-GCK          EGLLRQWLRTVAEHLDTPAAPRRTRKKGNR
Mvan_2233|M.vanbaalenii_PYR-1       ------------------------------