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IGETTSPTQRSGVRDEMLHAAVALLDAHGPDALQTRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQ FDTALAVPPSDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGINAPTQNVLTLTISQIEQRHPSFA HVVRGVRRSMLAGRITVNGGADRNRASAPDGLATDVPDAEIVATAAQFWALIHGFVMLELAGFFGDEGAA IEPVLASMTTNLLVALGDSPELAKRSQRLATGAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0992 | - | - | 100% (245) | transcriptional regulatory protein |
| M. marinum M | MMAR_4304 | - | 9e-06 | 25.76% (229) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0672c | - | 5e-88 | 71.00% (231) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2110 | - | 2e-33 | 37.39% (230) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0653c | - | 5e-88 | 71.00% (231) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3875 | - | 1e-65 | 57.38% (237) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4506 | - | 3e-86 | 70.04% (237) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1506 | - | 4e-07 | 35.16% (91) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4347 | - | 4e-37 | 41.88% (234) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0743 | - | 1e-133 | 97.14% (245) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3167 | - | 2e-07 | 25.11% (227) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2110|M.gilvum_PYR-GCK ------------------------MVSTVRD----NLVAAGVRLLEGGGV
TH_4347|M.thermoresistible__bu -----------------------VTADDIRE----KLVDAGVRLLERDGV
Mb0672c|M.bovis_AF2122/97 ------------------MTS----QTGVRD----ELLHAGVRLLDDHGP
Rv0653c|M.tuberculosis_H37Rv ------------------MTS----QTGVRD----ELLHAGVRLLDDHGP
MMAR_0992|M.marinum_M ---------------MIGETTSPTQRSGVRD----EMLHAAVALLDAHGP
MUL_0743|M.ulcerans_Agy99 ---------------MIGETTSPTQRSGVRD----EMLHAAVALLDAHGP
MAV_4506|M.avium_104 ------------------MTSQPAPQRNVRD----GMLAAAVALLHEHGA
MAB_3875|M.abscessus_ATCC_1997 MNVLPLCEHGKTMSSSARRNSEGTDRAVVRNPRV-DLVSAAVRLLNEQGP
Mvan_3167|M.vanbaalenii_PYR-1 ----------------MCDTGRVGKRQDTRDRIERQIVEIGRAHLVTHGA
MSMEG_1506|M.smegmatis_MC2_155 MRPGGAARKSWSEIGNYGQVGRPNRQAQRRE----EILDAAIALIERHDL
*: :: . : .
Mflv_2110|M.gilvum_PYR-GCK SALSARSVATEAGTSTMALYTHFGGMTGLLDAVAVDVFARFTEALTEVA-
TH_4347|M.thermoresistible__bu QALSARNLAAEAGTSTMAVYTRFGGMPGVLEAVAGEIFARFADALTQIP-
Mb0672c|M.bovis_AF2122/97 DALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP--
Rv0653c|M.tuberculosis_H37Rv DALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP--
MMAR_0992|M.marinum_M DALQTRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQFDTALAVP--
MUL_0743|M.ulcerans_Agy99 DALQTRKVAGATGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALAVP--
MAV_4506|M.avium_104 DALQTRKVAGAAGTSTMAVYTHFGGMRGLIAEVAEEGLRQFDAALTVP--
MAB_3875|M.abscessus_ATCC_1997 DALQTRKIAAAAGTSTMAVYTYFGGMRELIAEVAEAGLRQFAEAQAAVE-
Mvan_3167|M.vanbaalenii_PYR-1 AALSLRAIARELGMVSSAVYRYVASRDELLTLLLVDAYGELADSVERARD
MSMEG_1506|M.smegmatis_MC2_155 ATLRIADVAAELGLTPNAVRYYFKEMDQLLSELAQRSDTRFYDDRLAVV-
:* :* * . *: . :: : .:
Mflv_2110|M.gilvum_PYR-GCK -PTDDPVADFLMMGLAYHRFALANPQRYQLIFGAAAPASISRFRADITET
TH_4347|M.thermoresistible__bu -QTGDPVADFLLMGAAYREYALTHPQRYLLMFGTATPASIAGSRADLTAT
Mb0672c|M.bovis_AF2122/97 -QTADPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGIN-VPARDVLT
Rv0653c|M.tuberculosis_H37Rv -QTADPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGIN-VPARDVLT
MMAR_0992|M.marinum_M -PSDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APTQNVLT
MUL_0743|M.ulcerans_Agy99 -PSDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APAQNVLT
MAV_4506|M.avium_104 -PTDDPVADLFVIGAAYRRYAIKHRHMYRLMFGSTSAHGIN-APAHNVLT
MAB_3875|M.abscessus_ATCC_1997 -QSDDVIADFMLTGMAYRQFAIDYPHMYRLMFGVTSAHGVN-APRRNMFD
Mvan_3167|M.vanbaalenii_PYR-1 AAAGDWQDRLRAVAHATRAWAVHHPARWALLYGSPVPGYHAPREQTVGPG
MSMEG_1506|M.smegmatis_MC2_155 ERIDDPCAQLALTIGAGLPTGPED-AEWRAIWRAVLAAGFELDQRR----
* : * . : :: .
Mflv_2110|M.gilvum_PYR-GCK GSATNRAEWAASFGALHGAVHRMMAAGRIR--------------------
TH_4347|M.thermoresistible__bu GEVSDRTEWAASFEALRTMVRRMIAAGRIR--------------------
Mb0672c|M.bovis_AF2122/97 LKVAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD-------------
Rv0653c|M.tuberculosis_H37Rv LKVAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD-------------
MMAR_0992|M.marinum_M LTISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGADRNRASAPDGLATDV
MUL_0743|M.ulcerans_Agy99 LTISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGDDRNRAAAPDGLATDV
MAV_4506|M.avium_104 LTVAEIEQNYPSFAHVVRAVHRCMRAGRITAGSADD--------------
MAB_3875|M.abscessus_ATCC_1997 T--SHVTPEHPSAAYLFRCVQRAMAAGRIDGSPED---------------
Mvan_3167|M.vanbaalenii_PYR-1 TRVVGLLFSAIAEGVAAGAVRTSKVTVPQSLSSDFDRLR-----AEFEFV
MSMEG_1506|M.smegmatis_MC2_155 ----DVQHIYHRQVGLYTDIL-----------------------------
:
Mflv_2110|M.gilvum_PYR-GCK -RDDELAVAGRLWSINHGAVMLEMAGFFGHEGHGLVHILGPLIIDTLVGM
TH_4347|M.thermoresistible__bu -DDGEAAIAGRLWSLIHGEVMLELAGFFGAEGHGLTKILTPMTVDMLVGL
Mb0672c|M.bovis_AF2122/97 -DTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVAL
Rv0653c|M.tuberculosis_H37Rv -DTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVAL
MMAR_0992|M.marinum_M PDAEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVAL
MUL_0743|M.ulcerans_Agy99 LDAEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVAL
MAV_4506|M.avium_104 -DGAVVATAAQFWASIHGFVMLELAGYCGDDGSAVLPVLGSMTSNLLVAL
MAB_3875|M.abscessus_ATCC_1997 -AAKVAATAAKFWTVMHGFVMLELAGFWGEDGAAVGPVLASMTTDLLVAL
Mvan_3167|M.vanbaalenii_PYR-1 ADDDVVARCLVLWAALVGAISLEVFGQYGADTFADASVVFDAQMDLVIDL
MSMEG_1506|M.smegmatis_MC2_155 -DGGARAGAFELRSPAH-DVAMTLMAMEDYLGYRIVARDPDLDRETALRL
* . : : : : : . . : : :
Mflv_2110|M.gilvum_PYR-GCK GDDRDAATLSMQTVVARLG------
TH_4347|M.thermoresistible__bu GDDRARVEASLTTAAEAHGR-----
Mb0672c|M.bovis_AF2122/97 GDSPERAQCSLRAEQTQKNTLGRAT
Rv0653c|M.tuberculosis_H37Rv GDSPERAQCSLRAEQTQKNTLGRAT
MMAR_0992|M.marinum_M GDSPELAKRSQRLATGAG-------
MUL_0743|M.ulcerans_Agy99 GDSPELAKRSQRLTTGAG-------
MAV_4506|M.avium_104 GDSPKRVSQSMRSAMLGS-------
MAB_3875|M.abscessus_ATCC_1997 GDTPERLNSSAAAAAARLAPSA---
Mvan_3167|M.vanbaalenii_PYR-1 FCRQGAN------------------
MSMEG_1506|M.smegmatis_MC2_155 MRGYAEIATGATLPVTA--------