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MDSGRRRLIDAGLALLTEQADREPSTRELYEAAGVAAPTLYHHFGTKEGLLEAVVTEAFSDYLERKRAVP DSGDLVADFAAGWDMHIEFGVQNPVLYRLMFGQAEERRSSARDIAETELRRRLQLLADEGLLRIDVDDAV SVTTGMAFGCVTQLIHSGGDATSAVAQAIRHALITELTGSPVRHDDPAQAARQVLAGLGTMPALFTPAEE GLLRQWLRTVAEHLDTPAAPRRTRKKGNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0941 | - | - | 100% (239) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2110 | - | 2e-10 | 35.65% (115) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2132 | - | 1e-07 | 32.99% (97) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0672c | - | 1e-10 | 33.04% (112) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0653c | - | 1e-10 | 33.04% (112) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3875 | - | 1e-10 | 33.68% (95) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0992 | - | 5e-09 | 33.67% (98) | transcriptional regulatory protein |
| M. avium 104 | MAV_0603 | - | 2e-08 | 28.19% (149) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5307 | - | 9e-19 | 32.61% (230) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4549 | - | 8e-24 | 30.53% (226) | PUTATIVE putative TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_0743 | - | 4e-09 | 26.54% (211) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4572 | - | 7e-08 | 32.99% (97) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0672c|M.bovis_AF2122/97 ----------------------MTSQTGVRD---ELLHAGVRLLDDHGPD
Rv0653c|M.tuberculosis_H37Rv ----------------------MTSQTGVRD---ELLHAGVRLLDDHGPD
MMAR_0992|M.marinum_M ---------------MIGETTSPTQRSGVRD---EMLHAAVALLDAHGPD
MUL_0743|M.ulcerans_Agy99 ---------------MIGETTSPTQRSGVRD---EMLHAAVALLDAHGPD
MAB_3875|M.abscessus_ATCC_1997 MNVLPLCEHGKTMSSSARRNSEGTDRAVVRNPRVDLVSAAVRLLNEQGPD
MSMEG_5307|M.smegmatis_MC2_155 ------------------MAKATSSVLPPAE---RILAAAADLLRAGGID
TH_4549|M.thermoresistible__bu ------------------VDGLTEQQREQRE---RILRAAAEILAEQGRD
Mflv_0941|M.gilvum_PYR-GCK -------------------------MDSGRR---RLIDAGLALLTEQADR
Mvan_4572|M.vanbaalenii_PYR-1 ----------MADVSAPRQRRHRAPRGAGEQLRAEILDAATDLLLETGDE
MAV_0603|M.avium_104 ---------------------MTGPANSRRD---ELLELAAAMFAERGLR
:: . :: .
Mb0672c|M.bovis_AF2122/97 -ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP-Q
Rv0653c|M.tuberculosis_H37Rv -ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP-Q
MMAR_0992|M.marinum_M -ALQTRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQFDTALAVP-P
MUL_0743|M.ulcerans_Agy99 -ALQTRKVAGATGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALAVP-P
MAB_3875|M.abscessus_ATCC_1997 -ALQTRKIAAAAGTSTMAVYTYFGGMRELIAEVAEAGLRQFAEAQAAVEQ
MSMEG_5307|M.smegmatis_MC2_155 -AVSTRAVATEAGVQPPTIYRQFGDKDGLLDAVTRHVLESYIDRKR--LL
TH_4549|M.thermoresistible__bu -AVTTRNVSAAAGVQPPTIYRHFGDMRRLIDDAASLGMAEYLKAKRERAL
Mflv_0941|M.gilvum_PYR-GCK -EPSTRELYEAAGVAAPTLYHHFGTKEGLLEAVVTEAFSDYLERKRAVPD
Mvan_4572|M.vanbaalenii_PYR-1 KAVSIRSVAQRVGVTPPSIYLHFVDKTALLDAVCGRYFEKLDEEMQEVAG
MAV_0603|M.avium_104 -ATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLFARYREIID
* : .* . ::* * :: :
Mb0672c|M.bovis_AF2122/97 TA---DPVADLLAIGTAYRRYAIERPHMYRLMFGSTS---AHGINVPARD
Rv0653c|M.tuberculosis_H37Rv TA---DPVADLLAIGTAYRRYAIERPHMYRLMFGSTS---AHGINVPARD
MMAR_0992|M.marinum_M SD---DPVADLVATGAAYRRYAIERPHMYRLMFGSTS---AHGINAPTQN
MUL_0743|M.ulcerans_Agy99 SD---DPVADLVATGAAYRRYAIERPHMYRLMFGSTS---AHGINAPAQN
MAB_3875|M.abscessus_ATCC_1997 SD---DVIADFMLTGMAYRQFAIDYPHMYRLMFGVTS---AHGVNAPRRN
MSMEG_5307|M.smegmatis_MC2_155 TDPDADPALILRELWDLHVEFGMQQPHCYLLTYGQGR---RTSAADETVS
TH_4549|M.thermoresistible__bu TD---DPVHDLRDGWDLHVEFGLRHPATYTVLYGDPRPDAKPRAVAEGDA
Mflv_0941|M.gilvum_PYR-GCK SG---DLVADFAAGWDMHIEFGVQNPVLYRLMFGQAE-ERRSSARDIAET
Mvan_4572|M.vanbaalenii_PYR-1 AA--ATALDVLRAQGMAYVRFALKNPVLYRIAMMGPG--SPGSDVDVALN
MAV_0603|M.avium_104 SE--SNPLERLKGLFMASFE-AIEHRHAQVVIYQDEA----------KRL
: : . .: :
Mb0672c|M.bovis_AF2122/97 VLTLKVAEIEHQHPSFAHVVRAVHRCLLAGR-FATALGADD---------
Rv0653c|M.tuberculosis_H37Rv VLTLKVAEIEHQHPSFAHVVRAVHRCLLAGR-FATALGADD---------
MMAR_0992|M.marinum_M VLTLTISQIEQRHPSFAHVVRGVRRSMLAGR-ITVNGGADRNRASAPDGL
MUL_0743|M.ulcerans_Agy99 VLTLTISQIEQRHPSFAHVVRGVRRSMLAGR-ITVNGGDDRNRAAAPDGL
MAB_3875|M.abscessus_ATCC_1997 MFDT--SHVTPEHPSAAYLFRCVQRAMAAGR-IDGS--PED---------
MSMEG_5307|M.smegmatis_MC2_155 ILGEVIGRLGAAGRLTMSVRRATDYFRASGTGFVMSQLSLAS--------
TH_4549|M.thermoresistible__bu ILRSLMQRVAEAGRLRIGVDRAAEMMHSACRGVTLTLISQTP--------
Mflv_0941|M.gilvum_PYR-GCK ELRRRLQLLADEGLLRIDVDDAVSVTTGMAFGCVTQLIHSGG--------
Mvan_4572|M.vanbaalenii_PYR-1 SSAFGHLLMSVQALIAEGVYPQADPTMLALE-------------------
MAV_0603|M.avium_104 LSQPRFSYIEDMNRQQRKMWLEVLNQGVDEG-------------------
: : .
Mb0672c|M.bovis_AF2122/97 -----DTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNL
Rv0653c|M.tuberculosis_H37Rv -----DTAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNL
MMAR_0992|M.marinum_M ATDVPDAEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNL
MUL_0743|M.ulcerans_Agy99 ATDVLDAEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNL
MAB_3875|M.abscessus_ATCC_1997 -----AAKVAATAAKFWTVMHGFVMLELAGFWGEDGAAVGPVLASMTTDL
MSMEG_5307|M.smegmatis_MC2_155 -----EERDAELSGIIFEATLAAVSTDGRRGRGRKANDVRARAVALREAL
TH_4549|M.thermoresistible__bu -----AERDPELSAATREAMLAAITTGGAAGPADGAG-VATRAIALKSVL
Mflv_0941|M.gilvum_PYR-GCK -----DATSAVAQAIRHALITELTGSPVRHDDPAQAARQVLAGLGTMPAL
Mvan_4572|M.vanbaalenii_PYR-1 ------LWTAVHGIAAMLISRPYLPWGGAEEFADRLMRAVCCGQALSVAI
MAV_0603|M.avium_104 -----YFRPDLDVDLVYRFIRDTTWVSVRWYQPGGPLTAEQVGQQYLAIV
:
Mb0672c|M.bovis_AF2122/97 LVALGDSPERAQCSLRAEQTQKNTLGRAT------
Rv0653c|M.tuberculosis_H37Rv LVALGDSPERAQCSLRAEQTQKNTLGRAT------
MMAR_0992|M.marinum_M LVALGDSPE------LAKRSQRLATGAG-------
MUL_0743|M.ulcerans_Agy99 LVALGDSPE------LAKRSQRLTTGAG-------
MAB_3875|M.abscessus_ATCC_1997 LVALGDTPERLN-SSAAAAAARLAPSA--------
MSMEG_5307|M.smegmatis_MC2_155 PESRTPALSAAEQGLLAEWLDRLADQA--------
TH_4549|M.thermoresistible__bu ETGGAGVLTEAEAELLKEWLDRLSQ----------
Mflv_0941|M.gilvum_PYR-GCK FTPAEEGLLRQWLRTVAEHLDTPAAPRRTRKKGNR
Mvan_4572|M.vanbaalenii_PYR-1 RPDESPREIMTWLKEVVDERQRG------------
MAV_0603|M.avium_104 LGGITVDAKKD------------------------