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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4347 | - | - | 100% (221) | transcriptional regulator, TetR family |
| M. thermoresistible (build 8) | TH_4549 | - | 1e-10 | 26.90% (145) | PUTATIVE putative TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_1893 | - | 4e-09 | 24.23% (194) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0672c | - | 3e-42 | 46.95% (213) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2110 | - | 3e-72 | 62.15% (214) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0653c | - | 3e-42 | 46.95% (213) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3875 | - | 5e-40 | 43.46% (214) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0992 | - | 5e-37 | 41.88% (234) | transcriptional regulatory protein |
| M. avium 104 | MAV_4506 | - | 6e-38 | 43.98% (216) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0042 | - | 1e-10 | 30.81% (172) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_0743 | - | 6e-37 | 41.20% (233) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1278 | - | 6e-10 | 23.62% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4347|M.thermoresistible__bu ---------------VTADD--------IRE---KLVDAGVRLLERDGVQ
Mflv_2110|M.gilvum_PYR-GCK ----------------MVST--------VRD---NLVAAGVRLLEGGGVS
Mb0672c|M.bovis_AF2122/97 --------------MTSQTG--------VRD---ELLHAGVRLLDDHGPD
Rv0653c|M.tuberculosis_H37Rv --------------MTSQTG--------VRD---ELLHAGVRLLDDHGPD
MMAR_0992|M.marinum_M -------MIGETTSPTQRSG--------VRD---EMLHAAVALLDAHGPD
MUL_0743|M.ulcerans_Agy99 -------MIGETTSPTQRSG--------VRD---EMLHAAVALLDAHGPD
MAV_4506|M.avium_104 ----------MTSQPAPQRN--------VRD---GMLAAAVALLHEHGAD
MAB_3875|M.abscessus_ATCC_1997 MNVLPLCEHGKTMSSSARRNSEGTDRAVVRNPRVDLVSAAVRLLNEQGPD
MSMEG_0042|M.smegmatis_MC2_155 ----------MAMEERRERE-----RAARRD---LIISTARRLAEAEGWQ
Mvan_1278|M.vanbaalenii_PYR-1 ----------MAVRPPRTAK-------LSRD---AIVNAALTFLDREGWD
*: :: :. : . * .
TH_4347|M.thermoresistible__bu ALSARNLAAEAGTSTMAVYTRFGGMPGVLEAVAGEIFARFADALTQIP-Q
Mflv_2110|M.gilvum_PYR-GCK ALSARSVATEAGTSTMALYTHFGGMTGLLDAVAVDVFARFTEALTEVA-P
Mb0672c|M.bovis_AF2122/97 ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP--Q
Rv0653c|M.tuberculosis_H37Rv ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP--Q
MMAR_0992|M.marinum_M ALQTRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQFDTALAVP--P
MUL_0743|M.ulcerans_Agy99 ALQTRKVAGATGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALAVP--P
MAV_4506|M.avium_104 ALQTRKVAGAAGTSTMAVYTHFGGMRGLIAEVAEEGLRQFDAALTVP--P
MAB_3875|M.abscessus_ATCC_1997 ALQTRKIAAAAGTSTMAVYTYFGGMRELIAEVAEAGLRQFAEAQAAVE-Q
MSMEG_0042|M.smegmatis_MC2_155 AVTTRRLSAEIEYSQPVLYKHFAGMEELADAVALDGFGELAEAMRQARRG
Mvan_1278|M.vanbaalenii_PYR-1 ALTINALANQLGTKGPSLYNHVHSLDDLRRTVRMHVVGDIIEMLNTVG-K
*: . :: . :*. . .: : : . :
TH_4347|M.thermoresistible__bu TGDPVADFLLMGAAYREYALTHPQRYLLMFGTATPASIAGSRADLTATGE
Mflv_2110|M.gilvum_PYR-GCK TDDPVADFLMMGLAYHRFALANPQRYQLIFGAAAPASISRFRADITETGS
Mb0672c|M.bovis_AF2122/97 TADPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGIN-VPARDVLTLK
Rv0653c|M.tuberculosis_H37Rv TADPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGIN-VPARDVLTLK
MMAR_0992|M.marinum_M SDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APTQNVLTLT
MUL_0743|M.ulcerans_Agy99 SDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APAQNVLTLT
MAV_4506|M.avium_104 TDDPVADLFVIGAAYRRYAIKHRHMYRLMFGSTSAHGIN-APAHNVLTLT
MAB_3875|M.abscessus_ATCC_1997 SDDVIADFMLTGMAYRQFAIDYPHMYRLMFGVTSAHGVN-APRRNMFDT-
MSMEG_0042|M.smegmatis_MC2_155 DDHPDHAVTRIAQAYLDFARANPAVYDAMFARATNLRFAADDTP------
Mvan_1278|M.vanbaalenii_PYR-1 GRTPDDAVMVMASAYRSYAHHHPGRYSAFTRMPLGGDDP-----------
. . ** :* * : .
TH_4347|M.thermoresistible__bu VSDRTEWAASFEALRTMVRRMIAAGRIRDD--------------------
Mflv_2110|M.gilvum_PYR-GCK ATNRAEWAASFGALHGAVHRMMAAGRIRRD--------------------
Mb0672c|M.bovis_AF2122/97 VAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD--------------D
Rv0653c|M.tuberculosis_H37Rv VAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD--------------D
MMAR_0992|M.marinum_M ISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGADRNRASAPDGLATDVPD
MUL_0743|M.ulcerans_Agy99 ISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGDDRNRAAAPDGLATDVLD
MAV_4506|M.avium_104 VAEIEQNYPSFAHVVRAVHRCMRAGRITAG-SADD--------------D
MAB_3875|M.abscessus_ATCC_1997 -SHVTPEHPSAAYLFRCVQRAMAAGRIDGS--PED--------------A
MSMEG_0042|M.smegmatis_MC2_155 ----SPLTEAFAQLRDAVGRNEDAD-------------------------
Mvan_1278|M.vanbaalenii_PYR-1 -----EFTEATRAAAAPVISVLETFGLESE--------------------
: * :
TH_4347|M.thermoresistible__bu -GEAAIAGRLWSLIHGEVMLELAGFFGAEGHGLTKILTPMTVDMLVGLGD
Mflv_2110|M.gilvum_PYR-GCK -DELAVAGRLWSINHGAVMLEMAGFFGHEGHGLVHILGPLIIDTLVGMGD
Mb0672c|M.bovis_AF2122/97 TAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVALGD
Rv0653c|M.tuberculosis_H37Rv TAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVALGD
MMAR_0992|M.marinum_M AEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGD
MUL_0743|M.ulcerans_Agy99 AEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGD
MAV_4506|M.avium_104 GAVVATAAQFWASIHGFVMLELAGYCGDDGSAVLPVLGSMTSNLLVALGD
MAB_3875|M.abscessus_ATCC_1997 AKVAATAAKFWTVMHGFVMLELAGFWGEDGAAVGPVLASMTTDLLVALGD
MSMEG_0042|M.smegmatis_MC2_155 ----TLTEVLWAALHGLVMLGRTG-------RLRPDHETERLQLLVDRMS
Mvan_1278|M.vanbaalenii_PYR-1 -SAFYAALEFWSAMHGFVLLEMTGVMS--GIDTDAVFTDMVARLAAGMQL
: :*: ** *:* :* .
TH_4347|M.thermoresistible__bu DRA------RVEASLTTAAEAHGR
Mflv_2110|M.gilvum_PYR-GCK DRD------AATLSMQTVVARLG-
Mb0672c|M.bovis_AF2122/97 SPERAQCSLRAEQTQKNTLGRAT-
Rv0653c|M.tuberculosis_H37Rv SPERAQCSLRAEQTQKNTLGRAT-
MMAR_0992|M.marinum_M SPE------LAKRSQRLATGAG--
MUL_0743|M.ulcerans_Agy99 SPE------LAKRSQRLTTGAG--
MAV_4506|M.avium_104 SPK------RVSQSMRSAMLGS--
MAB_3875|M.abscessus_ATCC_1997 TPERLN-SSAAAAAARLAPSA---
MSMEG_0042|M.smegmatis_MC2_155 R-----------------------
Mvan_1278|M.vanbaalenii_PYR-1 R-----------------------