For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VNVLPLCEHGKTMSSSARRNSEGTDRAVVRNPRVDLVSAAVRLLNEQGPDALQTRKIAAAAGTSTMAVYT YFGGMRELIAEVAEAGLRQFAEAQAAVEQSDDVIADFMLTGMAYRQFAIDYPHMYRLMFGVTSAHGVNAP RRNMFDTSHVTPEHPSAAYLFRCVQRAMAAGRIDGSPEDAAKVAATAAKFWTVMHGFVMLELAGFWGEDG AAVGPVLASMTTDLLVALGDTPERLNSSAAAAAARLAPSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3875 | - | - | 100% (250) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3852c | - | 1e-08 | 24.39% (205) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3216c | - | 6e-08 | 25.44% (114) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0672c | - | 1e-63 | 58.41% (214) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2110 | - | 8e-37 | 39.64% (222) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0653c | - | 1e-63 | 58.41% (214) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0992 | - | 1e-65 | 57.38% (237) | transcriptional regulatory protein |
| M. avium 104 | MAV_4506 | - | 7e-65 | 59.26% (216) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0042 | - | 5e-09 | 30.99% (171) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4347 | - | 5e-40 | 43.46% (214) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0743 | - | 8e-65 | 57.89% (228) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5135 | - | 8e-10 | 28.90% (173) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2110|M.gilvum_PYR-GCK ------------------------MVSTVRD---NLVAAGVRLLEGGGVS
TH_4347|M.thermoresistible__bu -----------------------VTADDIRE---KLVDAGVRLLERDGVQ
MMAR_0992|M.marinum_M ---------------MIGETTSPTQRSGVRD---EMLHAAVALLDAHGPD
MUL_0743|M.ulcerans_Agy99 ---------------MIGETTSPTQRSGVRD---EMLHAAVALLDAHGPD
MAV_4506|M.avium_104 ------------------MTSQPAPQRNVRD---GMLAAAVALLHEHGAD
Mb0672c|M.bovis_AF2122/97 ------------------MTS----QTGVRD---ELLHAGVRLLDDHGPD
Rv0653c|M.tuberculosis_H37Rv ------------------MTS----QTGVRD---ELLHAGVRLLDDHGPD
MAB_3875|M.abscessus_ATCC_1997 MNVLPLCEHGKTMSSSARRNSEGTDRAVVRNPRVDLVSAAVRLLNEQGPD
Mvan_5135|M.vanbaalenii_PYR-1 -----------------MSSRGTYHHGDLRA---TILARAADLVAERGAD
MSMEG_0042|M.smegmatis_MC2_155 ---------------MAMEERRERERAARRD---LIISTARRLAEAEGWQ
* :: . * * .
Mflv_2110|M.gilvum_PYR-GCK ALSARSVATEAGTSTMALYTHFGGMTGLLDAVAVDVFARFTEALTEVA-P
TH_4347|M.thermoresistible__bu ALSARNLAAEAGTSTMAVYTRFGGMPGVLEAVAGEIFARFADALTQIP-Q
MMAR_0992|M.marinum_M ALQTRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQFDTALAVP--P
MUL_0743|M.ulcerans_Agy99 ALQTRKVAGATGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALAVP--P
MAV_4506|M.avium_104 ALQTRKVAGAAGTSTMAVYTHFGGMRGLIAEVAEEGLRQFDAALTVP--P
Mb0672c|M.bovis_AF2122/97 ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP--Q
Rv0653c|M.tuberculosis_H37Rv ALQTRKVAAAAGTSTMAVYTHFGGMRGLIAAIAEEGLRQFDVALTVP--Q
MAB_3875|M.abscessus_ATCC_1997 ALQTRKIAAAAGTSTMAVYTYFGGMRELIAEVAEAGLRQFAEAQAAVE-Q
Mvan_5135|M.vanbaalenii_PYR-1 GVSLRELARAAGVSHAAPAHHFTDRRGLFTALATEGFRSLAEELSRA---
MSMEG_0042|M.smegmatis_MC2_155 AVTTRRLSAEIEYSQPVLYKHFAGMEELADAVALDGFGELAEAMRQARRG
.: * :: * . * . : :* : :
Mflv_2110|M.gilvum_PYR-GCK TDDPVADFLMMGLAYHRFALANPQRYQLIFGAAAPASISRFRADITETGS
TH_4347|M.thermoresistible__bu TGDPVADFLLMGAAYREYALTHPQRYLLMFGTATPASIAGSRADLTATGE
MMAR_0992|M.marinum_M SDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APTQNVLTLT
MUL_0743|M.ulcerans_Agy99 SDDPVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGIN-APAQNVLTLT
MAV_4506|M.avium_104 TDDPVADLFVIGAAYRRYAIKHRHMYRLMFGSTSAHGIN-APAHNVLTLT
Mb0672c|M.bovis_AF2122/97 TADPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGIN-VPARDVLTLK
Rv0653c|M.tuberculosis_H37Rv TADPVADLLAIGTAYRRYAIERPHMYRLMFGSTSAHGIN-VPARDVLTLK
MAB_3875|M.abscessus_ATCC_1997 SDDVIADFMLTGMAYRQFAIDYPHMYRLMFGVTSAHGVN-APRRNMFDT-
Mvan_5135|M.vanbaalenii_PYR-1 ----RPEFLDAALAYVRFALANPGHYEVMFDKSLYHADD--------PAL
MSMEG_0042|M.smegmatis_MC2_155 DDHPDHAVTRIAQAYLDFARANPAVYDAMFARATNLRFA----------A
. . ** :* * :* :
Mflv_2110|M.gilvum_PYR-GCK ATNRAEWAASFGALHGAVHRMMAAGRIR---------------------R
TH_4347|M.thermoresistible__bu VSDRTEWAASFEALRTMVRRMIAAGRIR---------------------D
MMAR_0992|M.marinum_M ISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGADRNRASAPDGLATDVPD
MUL_0743|M.ulcerans_Agy99 ISQIEQRHPSFAHVVRGVRRSMLAGRITVNGGDDRNRAAAPDGLATDVLD
MAV_4506|M.avium_104 VAEIEQNYPSFAHVVRAVHRCMRAGRITAGSADD---------------D
Mb0672c|M.bovis_AF2122/97 VAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD--------------D
Rv0653c|M.tuberculosis_H37Rv VAEIEHQHPSFAHVVRAVHRCLLAGRFATALGADD--------------D
MAB_3875|M.abscessus_ATCC_1997 -SHVTPEHPSAAYLFRCVQRAMAAGRIDGSPED----------------A
Mvan_5135|M.vanbaalenii_PYR-1 VDAETAAGSELAAGVGTLDDPRAK--------------------------
MSMEG_0042|M.smegmatis_MC2_155 DDTPSPLTEAFAQLRDAVGR-----------------------------N
:
Mflv_2110|M.gilvum_PYR-GCK DDELAVAGRLWSINHGAVMLEMAGFFGHEGHGLVHILGPLIIDTLVGMGD
TH_4347|M.thermoresistible__bu DGEAAIAGRLWSLIHGEVMLELAGFFGAEGHGLTKILTPMTVDMLVGLGD
MMAR_0992|M.marinum_M AEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGD
MUL_0743|M.ulcerans_Agy99 AEIVATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGD
MAV_4506|M.avium_104 GAVVATAAQFWASIHGFVMLELAGYCGDDGSAVLPVLGSMTSNLLVALGD
Mb0672c|M.bovis_AF2122/97 TAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVALGD
Rv0653c|M.tuberculosis_H37Rv TAIVATAAQFWSQIHGFVMLELAGFYGDRGAAVEPVLAAMTVNLLVALGD
MAB_3875|M.abscessus_ATCC_1997 AKVAATAAKFWTVMHGFVMLELAGFWGEDGAAVGPVLASMTTDLLVALGD
Mvan_5135|M.vanbaalenii_PYR-1 DDPQAAALAAWSLVHGFALLWLNGAVNTTG----DPMATVRRVAGMLFGG
MSMEG_0042|M.smegmatis_MC2_155 EDADTLTEVLWAALHGLVMLGRTG----------RLRPDHETERLQLLVD
: : *: ** .:* * : .
Mflv_2110|M.gilvum_PYR-GCK DRDAATLSMQTVVARLG------
TH_4347|M.thermoresistible__bu DRARVEASLTTAAEAHGR-----
MMAR_0992|M.marinum_M SPELAKRSQRLATGAG-------
MUL_0743|M.ulcerans_Agy99 SPELAKRSQRLTTGAG-------
MAV_4506|M.avium_104 SPKRVSQSMRSAMLGS-------
Mb0672c|M.bovis_AF2122/97 SPERAQCSLRAEQTQKNTLGRAT
Rv0653c|M.tuberculosis_H37Rv SPERAQCSLRAEQTQKNTLGRAT
MAB_3875|M.abscessus_ATCC_1997 TPERLNSSAAAAAARLAPSA---
Mvan_5135|M.vanbaalenii_PYR-1 EPVTCPT----------------
MSMEG_0042|M.smegmatis_MC2_155 RMSR-------------------