For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4349 | - | - | 100% (349) | Alcohol dehydrogenase GroES domain protein |
| M. thermoresistible (build 8) | TH_4627 | - | 9e-36 | 33.52% (358) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. thermoresistible (build 8) | TH_2499 | - | 5e-31 | 32.00% (375) | PUTATIVE Alcohol dehydrogenase GroES domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3113 | adhD | 8e-36 | 34.73% (357) | zinc-type alcohol dehydrogenase AdhD |
| M. gilvum PYR-GCK | Mflv_4951 | - | 1e-43 | 36.09% (338) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3086 | adhD | 9e-36 | 34.73% (357) | zinc-type alcohol dehydrogenase AdhD |
| M. leprae Br4923 | MLBr_01784 | adhE2 | 4e-32 | 32.12% (358) | putative alcohol dehydrogenase (Zn dependent) |
| M. abscessus ATCC 19977 | MAB_2084 | - | 2e-34 | 32.35% (374) | zinc-type alcohol dehydrogenase AdhD |
| M. marinum M | MMAR_4911 | adhX | 2e-40 | 33.83% (337) | Zn-dependent alcohol dehydrogenase, AdhX |
| M. avium 104 | MAV_2804 | - | 7e-34 | 34.15% (325) | zinc-binding dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1977 | - | 9e-72 | 42.69% (349) | alcohol dehydrogenase |
| M. ulcerans Agy99 | MUL_0495 | adhX | 3e-40 | 33.83% (337) | Zn-dependent alcohol dehydrogenase, AdhX |
| M. vanbaalenii PYR-1 | Mvan_5450 | - | 4e-51 | 36.67% (360) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4349|M.thermoresistible__bu ----------------MKALRLMDWKSEPELVEVPDPTP-GPGQVLVKIG
MSMEG_1977|M.smegmatis_MC2_155 ----------------MRAVQVVGYHQNLELADVEKPTPTGPFDVVVKIG
Mvan_5450|M.vanbaalenii_PYR-1 --------------MKMRAARMYGYKQPLRLEEVDVPSP-GPEEVLVRVG
MMAR_4911|M.marinum_M MTQTLANPGATQATETLCAAVVTGFGEPLQIKELALPTP-GYGEALVKLE
MUL_0495|M.ulcerans_Agy99 MTQTLANPGATQATETLRAAVVTGFGEPLQIKELALPTP-GYGEALVKLE
Mflv_4951|M.gilvum_PYR-GCK ----------------MQAAVVTAFGEPLVVEERDLPAP-GPGEALVKLV
Mb3113|M.bovis_AF2122/97 --------------MKTTAAVLFEAGKPFELMELDLDGP-GPGEVLVKYT
Rv3086|M.tuberculosis_H37Rv --------------MKTTAAVLFEAGKPFELMELDLDGP-GPGEVLVKYT
MAB_2084|M.abscessus_ATCC_1997 --------------MKTRAAVLWGLEQKWEVEEVDLDPP-GPGEVLVRLA
MLBr_01784|M.leprae_Br4923 ------------MSQTVRGVISRKKDEPVELVDIVIPDP-GPGEAVVDVT
MAV_2804|M.avium_104 ----------------MRTVVVDG-PRSIRVDTRPDPVLPGPDGAIVEVS
: * .:*
TH_4349|M.thermoresistible__bu GAGACHSDLHLMHDFEPGMMPWQLPFTLGHENAGWVAAVGAGVGT---VT
MSMEG_1977|M.smegmatis_MC2_155 GAGVCRTDLHILEGQWAEKSQVQLPYTIGHENAGWVESVGSAVTN---VT
Mvan_5450|M.vanbaalenii_PYR-1 GAGMCRTDFQLIDGYFDNGLSMDFPITPGHEVAGWVDGVGSAVPKSAGLA
MMAR_4911|M.marinum_M TSGVCHTDLHAAHGDWP--VKPAPPFVPGHEGCGTVVALGDGVTD---LK
MUL_0495|M.ulcerans_Agy99 TSGVCHTDLHAAHGDWP--VKPAPPFVPGHEGCGTVVALGDGVTD---LK
Mflv_4951|M.gilvum_PYR-GCK TSGVCHTDLHAAHGDWP--VKPSPPFIPGHEGYGTVVAVGDGVDD---LS
Mb3113|M.bovis_AF2122/97 AAGLCHSDLHLTDGDLP----PRFPIVGGHEGSGVIEEVGAGVTR---VK
Rv3086|M.tuberculosis_H37Rv AAGLCHSDLHLTDGDLP----PRFPIVGGHEGSGVIEEVGAGVTR---VK
MAB_2084|M.abscessus_ATCC_1997 ATGLCHSDEHLVTGDLP----IPLPVVGGHEGAGTVVECGEGVED---LS
MLBr_01784|M.leprae_Br4923 ACGVCHTDLTYREGGIN----DRYPFLLGHEAAGTVEVVGPGVTA---VE
MAV_2804|M.avium_104 AAGICGSDLHFYEADFP----MPDPIALGHEAIGTVVEAGPQVRN---VK
* * :* * *** * : * * :
TH_4349|M.thermoresistible__bu EGDAVAVYGPWG-CGTCERCMGGAENYCENPAGAPVLSG----------G
MSMEG_1977|M.smegmatis_MC2_155 EGDKVIVHPLIT-CGLCRACRSGDDVHCESNAFP----------------
Mvan_5450|M.vanbaalenii_PYR-1 EGDQVVVFGSWG-DGACRQCHEGNEQLCAHGVWA----------------
MMAR_4911|M.marinum_M VGDKVGNAWLWSACGSCEQCRTGWETLCENQRNG----------------
MUL_0495|M.ulcerans_Agy99 VGDKVGNAWLWSACGSCEQCRTGWETLCENQRNG----------------
Mflv_4951|M.gilvum_PYR-GCK VGDMVGNAWLWSSCGRCEYCRTGWETLCEQQRNG----------------
Mb3113|M.bovis_AF2122/97 PGDHVVCSFIPN-CGTCRYCCTGRQNLCDMGATILEGCMPDGSFRFHSQG
Rv3086|M.tuberculosis_H37Rv PGDHVVCSFIPN-CGTCRYCCTGRQNLCDMGATILEGCMPDGSFRFHSQG
MAB_2084|M.abscessus_ATCC_1997 EGDSVILTFLPS-CGRCSYCARGMGNLCELGAALMMGPQIDGTYRFHARG
MLBr_01784|M.leprae_Br4923 PGDFVILNWRAV-CGQCRACKRGRPSYCFDTFNAQQKMT-------LIDG
MAV_2804|M.avium_104 VGDQVMVSSVAG-CGSCAGCATRDPVLCHSGFQIFG--------------
** * * * * *
TH_4349|M.thermoresistible__bu AGLGMDGGMAEYLLVPAERLVVKLP--ESMTPVTAAALTDAGLTPYHAIR
MSMEG_1977|M.smegmatis_MC2_155 -GIDTNGGYAEYLKT-SARSVVKID--DALEPADVAALADAGLTAYHAAA
Mvan_5450|M.vanbaalenii_PYR-1 -GFGRHGGYQEYLPV-NYRYLIKIPGGGELSPDNLAPLTDAGLTPYRGLK
MMAR_4911|M.marinum_M -GYTVNGSFGTYMLV-NADYAARIP--DGADPLEVAPILCAGVTVYKGLK
MUL_0495|M.ulcerans_Agy99 -GYTVNGSFGTYMLV-NADYAARIP--DGADPLEVAPILCAGVTVYKGLK
Mflv_4951|M.gilvum_PYR-GCK -GYSVDGSFGTYMLV-DAAYAARIP--DGVDPVEVAPILCAGVTVYKGLK
Mb3113|M.bovis_AF2122/97 TDFGAMCMLGTFAER-ATVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTA
Rv3086|M.tuberculosis_H37Rv TDFGAMCMLGTFAER-ATVSQHSVVKVDDWLPLETAVLVGCGVPSGWGTA
MAB_2084|M.abscessus_ATCC_1997 EDVGQMCLLGTFSEY-TVVPQASVVKIDGGIPLDRAALIGCGVTTGYGSA
MLBr_01784|M.leprae_Br4923 TELTPALGIGAFADK-TLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAA
MAV_2804|M.avium_104 -GGVLGGAQADLLAV--PAADFQLLKIPEGISTEQALLLTDNLATGWAAA
* : .: .
TH_4349|M.thermoresistible__bu --RSWPKLTPTSTAVVIGVGGLGHVAVQLVKATT-AARLIAVDNRSEALE
MSMEG_1977|M.smegmatis_MC2_155 --KAARRLTPRDRVVVIGAGGLGHIGIQVLKALS-PAELIVVDRNPEALK
Mvan_5450|M.vanbaalenii_PYR-1 KLRNAGHLGPGRTVAVSGIGGLGSYATQYAKLLGGGAEVVAFARSDEKLK
MMAR_4911|M.marinum_M ----VTDTRPGQWVAISGIGGLGHVAVQYARAMG--LRVVAIDIDDDKLA
MUL_0495|M.ulcerans_Agy99 ----VTDTRPGQWVAISGIGGLGHVAVQYARAMG--LRVVAIDIDDDKLA
Mflv_4951|M.gilvum_PYR-GCK ----VTDTRPGQWVAISGIGGLGHVAVQYARAMG--LRVVAIDVDDSKLD
Mb3113|M.bovis_AF2122/97 --VNAGNLRAGDTAVIYGVGGLGINAVQGATAAG-CKYVVVVDPVAFKRE
Rv3086|M.tuberculosis_H37Rv --VNAGNLRAGDTAVIYGVGGLGINAVQGATAAG-CKYVVVVDPVAFKRE
MAB_2084|M.abscessus_ATCC_1997 --VRTGEVRAGDTVVVVGAGGIGMNAIQGARIAG-ALAIVAVDPVNFKRE
MLBr_01784|M.leprae_Br4923 --INTAAVSRDDTVAVIGCGGVGDAAISGAALVG-ANRIIAVDIDDTKLE
MAV_2804|M.avium_104 ---QRADIPFGGTVAVIGLGAVGLCALRSALFQG-AATVFAVDQVDGRLA
..: * *.:* . :...
TH_4349|M.thermoresistible__bu LAREMGADHVVRSDEQAVEAIW----ELTGGRGADVLLDFVGADA--TIE
MSMEG_1977|M.smegmatis_MC2_155 LAEAIGADHCVIADGNQIEQVR----DLTGGHGAETVVDFVGEGG--ATS
Mvan_5450|M.vanbaalenii_PYR-1 IAKDNGADHVVNVRDKDTEDVRAELESATGRTELDAVIECAGSED--SIR
MMAR_4911|M.marinum_M LAARLGAELVVNARTSDVVAQVQ---EATGG--VHGVLVTAVHPQ--AFG
MUL_0495|M.ulcerans_Agy99 LAARLGAELVVNARTSDVVAQVQ---EATGG--VHGVLVTAVHPQ--AFG
Mflv_4951|M.gilvum_PYR-GCK LATGLGAEVVVNARTADVVAEVH---RATGG--VHGVLVTAVHRD--AFG
Mb3113|M.bovis_AF2122/97 TALKFGATHAF-ADAASAAAKVD---ELTWGQGADAALILVGTVDDEVVS
Rv3086|M.tuberculosis_H37Rv TALKFGATHAF-ADAASAAAKVD---ELTWGQGADAALILVGTVDDEVVS
MAB_2084|M.abscessus_ATCC_1997 QASGFGATHTA-ASMDEAWSLVS---DMTRGKLADVCILTTDVAEGSYTA
MLBr_01784|M.leprae_Br4923 WARTFGATHTVNALELEVVKTIQ---DLTSGFGVDVVIDTVGRPE--TWK
MAV_2804|M.avium_104 RAARWGATPLKAPALEAILAATG-------GRGADAVIDAVATDA--SLT
* ** . : .
TH_4349|M.thermoresistible__bu LARAAARPLGDVTIVG---IAGG-SVPLSFFSQPYEVSIQTTYWG---TR
MSMEG_1977|M.smegmatis_MC2_155 EGIAMLRRAGDYHVVG---YGEN-IDVPTIDVISTEINFIGNLVG---SY
Mvan_5450|M.vanbaalenii_PYR-1 LAFSLLAAEGAVASVG---LIGNRVDIPLFPLVAREYTFYGSFWG---NY
MMAR_4911|M.marinum_M QAIGLARRGGTIVFNG---LPPGDFPAPIFDIVLKGLTIRGSIVG---TR
MUL_0495|M.ulcerans_Agy99 QAIGLARRGGTIVFNG---LPPGDFPAPIFVIVLKGLTIRGSIVG---TR
Mflv_4951|M.gilvum_PYR-GCK QAIGLARRGGTIVFVG---LPPGDFPAPIFDIVLKGLTIRGSIVG---TR
Mb3113|M.bovis_AF2122/97 AATAVIGKGGTVVITGLADPAKLTVHVSGTDLTLHEKTIKGSLFGSCNPQ
Rv3086|M.tuberculosis_H37Rv AATAVIGKGGTVVITGLADPAKLTVHVSGTDLTLHEKTIKGSLFGSCNPQ
MAB_2084|M.abscessus_ATCC_1997 EALALVGKRGRVVVTAIGHPDESSISGSLLEMTLYEKQIRGALYGSSNAP
MLBr_01784|M.leprae_Br4923 QAFYARDLAGTVVLVGVPTP-DMRLDMPLLDFFSHGGSLKSSWYGDCLPE
MAV_2804|M.avium_104 EALNAVRPGGTVSVVG--VHDMNPFPLNALGCLIRSITLRMTTAP---VQ
. * . :
TH_4349|M.thermoresistible__bu PELVELLDLAARGLVHV---ESTTYPLDDALQAYRDLRAGRVRGRAVIVP
MSMEG_1977|M.smegmatis_MC2_155 NDLCDLMALAARGAVNL---HTQKYALDDFQSAITDLDNGNVRGRAILVP
Mvan_5450|M.vanbaalenii_PYR-1 NDLTEVLALARTGQLKH---SVTRVRFDDVNETLEAIARGDVLGRAVIVY
MMAR_4911|M.marinum_M QDMAEALDFYARGLIHP---TVEGAALEDINHVFERMERGQIDGRVVIDY
MUL_0495|M.ulcerans_Agy99 QDMAEALDFYARGLIHP---TVEGAALEDINHVFERMERGQIDGRVVIDY
Mflv_4951|M.gilvum_PYR-GCK QDMVEAIDFFARGLVHP---TVHTTRLDDINDVFDRMERGQIDGRVVIDY
Mb3113|M.bovis_AF2122/97 YDIVRLLRLYDAGQLMLDELVTTTYNLEQVNQGYQDLRDGKNIRGVIVH-
Rv3086|M.tuberculosis_H37Rv YDIVRLLRLYDAGQLMLDELVTTTYNLEQVNQGYQDLRDGKNIRGVIVH-
MAB_2084|M.abscessus_ATCC_1997 HDIPRLVELYSAGLLKLDELVTREYSLDQINEGYQDMRSGRNIRGLVRF-
MLBr_01784|M.leprae_Br4923 RDFPTLVDLYLQGRLPLGKFVSERIGLGDVEEAFHKIHGGKVLRSVVML-
MAV_2804|M.avium_104 RTWPELIPLLQSGRLDVDGIFTTTMPLDEAAIGYATAGSRSGDDVKILLK
: : * : : : :
TH_4349|M.thermoresistible__bu -
MSMEG_1977|M.smegmatis_MC2_155 -
Mvan_5450|M.vanbaalenii_PYR-1 D
MMAR_4911|M.marinum_M R
MUL_0495|M.ulcerans_Agy99 R
Mflv_4951|M.gilvum_PYR-GCK R
Mb3113|M.bovis_AF2122/97 -
Rv3086|M.tuberculosis_H37Rv -
MAB_2084|M.abscessus_ATCC_1997 -
MLBr_01784|M.leprae_Br4923 -
MAV_2804|M.avium_104 P