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M. thermoresistible (build 8) TH_4306 (-)

annotation: -
coordinates: 4581872 - 4583152
length: 427

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4306--100% (427)-
M. thermoresistible (build 8)TH_3090-1e-3932.23% (363) PUTATIVE putative conserved protein
M. thermoresistible (build 8)TH_3143-1e-2729.92% (381) PUTATIVE putative conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1464-4e-2227.49% (331) hypothetical protein Mb1464
M. gilvum PYR-GCKMflv_4621-1e-2326.79% (336) hypothetical protein Mflv_4621
M. tuberculosis H37RvRv1429-4e-2227.49% (331) hypothetical protein Rv1429
M. leprae Br4923MLBr_01052-9e-1925.85% (294) hypothetical protein MLBr_01052
M. abscessus ATCC 19977MAB_2657c-1e-2128.72% (296) hypothetical protein MAB_2657c
M. marinum MMMAR_4951-8e-3031.91% (329) hypothetical protein MMAR_4951
M. avium 104-----
M. smegmatis MC2 155MSMEG_6492-4e-0628.46% (260) GAF domain-containing protein
M. ulcerans Agy99MUL_3452-7e-2728.35% (395) hypothetical protein MUL_3452
M. vanbaalenii PYR-1Mvan_5765-4e-0627.78% (252) transcriptional regulator, CdaR

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01052|M.leprae_Br4923          -----------------------------------------MARQHPSPR
MAB_2657c|M.abscessus_ATCC_199      -------------------------MNEGSERVHTQSMTPDQLWPDASEP
Mb1464|M.bovis_AF2122/97            -----------------------------------MAEAG-------GGP
Rv1429|M.tuberculosis_H37Rv         -----------------------------------MAEAG-------GGP
Mflv_4621|M.gilvum_PYR-GCK          -----------------------------------MLDSSEVQDTP-GHA
MUL_3452|M.ulcerans_Agy99           -----------------------------------MAERNRTDDAVVGKI
MSMEG_6492|M.smegmatis_MC2_155      ------------MTWLGALRRLSASATAEEDLSHVLAEIAETARSLLGFD
Mvan_5765|M.vanbaalenii_PYR-1       MSSRTLSTALPFEHWLSALAEIGEAVGGDEPVAEVLDRVARTACTLLGYD
MMAR_4951|M.marinum_M               --------------------------------------------------
TH_4306|M.thermoresistible__bu      -----------------------MSYEGAWMSGLRPRSTPTVAAASPEPA
                                                                                      

MLBr_01052|M.leprae_Br4923          VRELIREGARIALNPTQEWIDQLDRATFAAN-----------------PA
MAB_2657c|M.abscessus_ATCC_199      VRRLIRELAEKMLARSGEVAGDLTAASLEDPRY---------------RT
Mb1464|M.bovis_AF2122/97            ISVIARHMQLIRDDFISELFDKMKAEIRGLD-------------------
Rv1429|M.tuberculosis_H37Rv         ISVIARHMQLIRDDFISELFDKMKAEIRGLD-------------------
Mflv_4621|M.gilvum_PYR-GCK          VHHLFRDLGDLVRELPESIHGLLIEQVAELA-------------------
MUL_3452|M.ulcerans_Agy99           VVEVVYRLSAQLAEATASIQGTLEREIVELR-------------------
MSMEG_6492|M.smegmatis_MC2_155      FCGVLLPDEQSRHLRVRGASGLSSDYVDRVNSDRPLVLHGG----SPSSR
Mvan_5765|M.vanbaalenii_PYR-1       FCAVFLPDEQGRALTIEGSYGLSADYIAQVNANRPILLDVRGDHEAPTSL
MMAR_4951|M.marinum_M               -------MQTCATQLARDIVDRYQSELPSIVP------------------
TH_4306|M.thermoresistible__bu      VQWARRVAGDGPVDWAVEHAYEFALHVLQEIP------------------
                                                                                      

MLBr_01052|M.leprae_Br4923          IANDPVLAKVVRRASRAHLVHWATANLRDPGAPVPAHLG-----------
MAB_2657c|M.abscessus_ATCC_199      IADDPVIAEVDARLTVSNLKHWLTSNISEPGHRVRPATG-----------
Mb1464|M.bovis_AF2122/97            --YDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP------------
Rv1429|M.tuberculosis_H37Rv         --YDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP------------
Mflv_4621|M.gilvum_PYR-GCK          --ADQQLKELLSDTVAANVDTWFSVVRHSIPFDRMESP------------
MUL_3452|M.ulcerans_Agy99           --GDVQLLDLLHASVEGNVAAVLNAIHYDIPIERVESP------------
MSMEG_6492|M.smegmatis_MC2_155      AFHTAEAVAIRDVTAEPGFELWAGIANEQGYRSMIAVPLVARGEVLGTLN
Mvan_5765|M.vanbaalenii_PYR-1       AYRTGDVVTLEDIELVPDFT-WGGVAQEQGYRALISAPLRRPGTVVGALN
MMAR_4951|M.marinum_M               ---DPPAVADQLASVEASVRQIAECIDSGEGPRLLDLT------------
TH_4306|M.thermoresistible__bu      -ELDGTGGRTRMVRVGAEACVLQVLMLLFDDRSDVEMP------------
                                                                                      

MLBr_01052|M.leprae_Br4923          ---PEPLTMARDLVR----------------------RGRDVLALD-IYR
MAB_2657c|M.abscessus_ATCC_199      ---SAMRTYARDVVL----------------------RGLTTDDIQ-SWR
Mb1464|M.bovis_AF2122/97            ---AAALAYARAAAQ----------------------RDIPLSGLVRAHR
Rv1429|M.tuberculosis_H37Rv         ---AAALAYARAAAQ----------------------RDIPLSGLVRAHR
Mflv_4621|M.gilvum_PYR-GCK          ---TAALEHARRMAQ----------------------REVPVNALLRAYR
MUL_3452|M.ulcerans_Agy99           ---TAALEYARRLAQ----------------------RGVPVNALVRAYR
MSMEG_6492|M.smegmatis_MC2_155      GYYGAVHTYTRFEVERMTLLANHAAIAVSSARRLDELRALTASLRRQRDA
Mvan_5765|M.vanbaalenii_PYR-1       GYRTAPHRFDRAEVSLVTTLATQVAIALGTA----QLRAKEQATIR---E
MMAR_4951|M.marinum_M               ---PATAAIGRSGVQ----------------------RNIALNDLFRSVR
TH_4306|M.thermoresistible__bu      ---DEQEQVVRDCVH----------------------RKVPLDRLFSAIR
                                              *  .                       *            

MLBr_01052|M.leprae_Br4923          VGQYTAWRRWMEIAFTLTSDPQELREILNVSAQSINEYVAATLEAIA---
MAB_2657c|M.abscessus_ATCC_199      AVQRVGWKWWLAACFQVTDDKEQLCELIEVTSNSLTTFVDDSIAELA---
Mb1464|M.bovis_AF2122/97            LGHARFLEVAMQ--YVSLLEPADRVSTIIELVNRSARLVDLVADQLI---
Rv1429|M.tuberculosis_H37Rv         LGHARFLEVAMQ--YVSLLEPADRVSTIIELVNRSARLVDLVADQLI---
Mflv_4621|M.gilvum_PYR-GCK          LGHQYGLNLIIAGLRSADLPPEEKLALIEHITRVSFRYIDWMSEQVL---
MUL_3452|M.ulcerans_Agy99           LGHKEMLERIIDGVQEAGADPALSLDVFNRISEVTFNYIDWISQQVV---
MSMEG_6492|M.smegmatis_MC2_155      LTRSEQIHDRLLAVTLRSGGLDGIAAVLQGLIGRPILIDDIQHEVLACSV
Mvan_5765|M.vanbaalenii_PYR-1       LRRAEEVHTLLTATALRGEGVSGVAAALSELLGRGVLIEDVYDEPLT---
MMAR_4951|M.marinum_M               MAQERTWQWLFDRITASS-AATDHDRALDLATNWLFGYVDVVLIRAER--
TH_4306|M.thermoresistible__bu      NTHAWVTRIFMDACIELAPPSQQ-VAELRRISSITLAVFDRYTERAD---
                                      :    .  :                :                      

MLBr_01052|M.leprae_Br4923          ---------------------------------------------THMQL
MAB_2657c|M.abscessus_ATCC_199      ---------------------------------------------EHVRR
Mb1464|M.bovis_AF2122/97            ---------------------------------------------VAYEH
Rv1429|M.tuberculosis_H37Rv         ---------------------------------------------VAYEH
Mflv_4621|M.gilvum_PYR-GCK          ---------------------------------------------ETYQT
MUL_3452|M.ulcerans_Agy99           ---------------------------------------------AAYEA
MSMEG_6492|M.smegmatis_MC2_155      VTTDFPDTTWRAAAEAGTGSSPVPVGQFDGTTYLASAVHLGDEVAARIWF
Mvan_5765|M.vanbaalenii_PYR-1       ------DANWTAPDPR-------------AQDHVVATVTLDGSPVARIHV
MMAR_4951|M.marinum_M               ----------------------------------------------LYEV
TH_4306|M.thermoresistible__bu      ---------------------------------------------VAYRA
                                                                                      

MLBr_01052|M.leprae_Br4923          ERDELTRSTHAERLEVVDLILEGAPVTQERAEARLGYRLG-LTHTAAVIW
MAB_2657c|M.abscessus_ATCC_199      VREELAGGSQLQRYATVELLLQGADIAPARAEAQLGYALT-GSHIGAVVW
Mb1464|M.bovis_AF2122/97            EHDRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRLD-GVHIAAVVW
Rv1429|M.tuberculosis_H37Rv         EHDRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRLD-GVHIAAVVW
Mflv_4621|M.gilvum_PYR-GCK          ERAEWDERRRSLRAQAIRDILNGRDVDLTEASSAMRYFLG-ATHVALMVW
MUL_3452|M.ulcerans_Agy99           ERDRWLENRSRVRNVRIAEILDGGDIDTDAMTKSIRYPLR-KVHLALVLW
MSMEG_6492|M.smegmatis_MC2_155      PETSIDLDPIMVRAVEHASIVTALELLRCQTAAEVEQRLR-GELLSDVLS
Mvan_5765|M.vanbaalenii_PYR-1       AASDSELSRLDVRAVEHATVVTALELLRARTAAEVEQRIR-GSLVADLLS
MMAR_4951|M.marinum_M               EREAWLTGAAAARAAAVEDILTEREDDAQRASTRLRYDVN-RHHVGVSVW
TH_4306|M.thermoresistible__bu      EAERWFAGDQATREELVQTLLTRDDADTDRISQRLRYPVTGRNHLGVVAW
                                                :      ::             :   :      .    

MLBr_01052|M.leprae_Br4923          SDDLDGDHGYLDQAAEAFSHVVE---------------------------
MAB_2657c|M.abscessus_ATCC_199      VDSEK-EIAALERASEQVMRACG---------------------------
Mb1464|M.bovis_AF2122/97            VDSAV-PIGDVVAQFDQVRCLLAGELGP----------------------
Rv1429|M.tuberculosis_H37Rv         VDSAV-PIGDVVAQFDQVRCLLAGELGP----------------------
Mflv_4621|M.gilvum_PYR-GCK          LDRDAGADTDEFIAMERFMQHAVSATG-----------------------
MUL_3452|M.ulcerans_Agy99           FPDDA-TDGNEFERLERFLDELAEHLG-----------------------
MSMEG_6492|M.smegmatis_MC2_155      SGAAL--SDRLLDRAHRLGHDLTVPHIAIVGAFTGLDPVAERRAYERSLV
Mvan_5765|M.vanbaalenii_PYR-1       SDDAG--IPALLDRARRLGWDLSG-----VQSLIALRPADER-----TLA
MMAR_4951|M.marinum_M               RDVTQDACAGPVTLTEALTQLTRAIAAQ----------------------
TH_4306|M.thermoresistible__bu      REAGTDAADDLAEAAAAWLRAAG---------------------------
                                                                                      

MLBr_01052|M.leprae_Br4923          ---------STQQLIVVASAATRWVWLADALALDVPEVQKALLNLS---K
MAB_2657c|M.abscessus_ATCC_199      ---------ADRRLTVVAGTVALWLWIPAKTTPTVAVLMDSLGRRS---G
Mb1464|M.bovis_AF2122/97            -----ELGPVANSLMVPTDEREARLWFSPAPTRAFAPSRIRAAFESAGIR
Rv1429|M.tuberculosis_H37Rv         -----ELGPVANSLMVPTDEREARLWFSPAPTRAFAPSRIRAAFESAGIR
Mflv_4621|M.gilvum_PYR-GCK          ---------AKQSVYFSIDRLVGCAWMTVHRPSDYLS-QLRDFVRAQPDG
MUL_3452|M.ulcerans_Agy99           ---------TGNALFVAADRITGWGWIPLRANDAGLTGRVRRFVAGHTDA
MSMEG_6492|M.smegmatis_MC2_155      LLAKESAAHRPKPVVAMHAGTIVMLWPAQDAADAAGAGEVVRQAMRAASA
Mvan_5765|M.vanbaalenii_PYR-1       AADRFTAGVTPHPLVALHRGDLVFVWPA-DTGPAVPVAHRLLEFLNAATI
MMAR_4951|M.marinum_M               ---------SVLAHPAGSKAIAGWLSRPQAFTAAELDVANICSGIHLPQD
TH_4306|M.thermoresistible__bu      ---------AAEVLVLNRAESAVWAWGATPSPP-----RSVPTDWTHSGG
                                                               .                      

MLBr_01052|M.leprae_Br4923          ARVAIGTSSAGIEGFRRSHLEALTAQRTLARLKSHQQ--VAFFAD--VQL
MAB_2657c|M.abscessus_ATCC_199      VRVALGRAATGMAGFRRTHMDAAAAQRLLARLGSPLS--VVRYED--VHL
Mb1464|M.bovis_AF2122/97            ARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD--VAP
Rv1429|M.tuberculosis_H37Rv         ARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD--VAP
Mflv_4621|M.gilvum_PYR-GCK          PRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARDPGVAL
MUL_3452|M.ulcerans_Agy99           PHVALGQALPGVEGFRRAHRQARNAHRVGVAV-GASAPAVMAVSDEGLSA
MSMEG_6492|M.smegmatis_MC2_155      DRQATVAVGPGDVASHR-ESYQTAKGALQVAIMSGRTAAVVGLDDLGIAG
Mvan_5765|M.vanbaalenii_PYR-1       PEAPTAAVSRQAAARELPGIFRTVRGALDLAGDR-DTATVIDLDEPTIDH
MMAR_4951|M.marinum_M               VRVAIGEPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN--VAV
TH_4306|M.thermoresistible__bu      VRIGHGTWHPGLQGFRLTHREARSAEHVAHLCPRIDS-RVVDYRG--VDL
                                     .           . .                       :       :  

MLBr_01052|M.leprae_Br4923          VSLITQNPEDAKEFITSTLG-DFESAS---PALQQTLLTFINEQCNASRA
MAB_2657c|M.abscessus_ATCC_199      MDLLSADPASADQFVTDVLG-EFQSAS---PVLHQTVLTYVEEALNRTST
Mb1464|M.bovis_AF2122/97            VALLADDLEELRRFVTDVLG-DLSVDDERNSWLRETLREFLLRNRSYVAT
Rv1429|M.tuberculosis_H37Rv         VALLADDLEELRRFVTDVLG-DLSVDDERNSWLRETLREFLLRNRSYVAT
Mflv_4621|M.gilvum_PYR-GCK          ASMLMTDDATLKEWIHDVLG-PLAQNTASDQRLRDTLRVFLRAGSSFKAA
MUL_3452|M.ulcerans_Agy99           AALMGADLPDAGAWVRETLG-PLSTDSDNDAVLRETLRVFLREGGSYKAA
MSMEG_6492|M.smegmatis_MC2_155      LLLRINDPAALSTFARRTLAPILDYDHAHRTELLVTLRAYLECRQERSAT
Mvan_5765|M.vanbaalenii_PYR-1       LLLQLDDPARLRDFASAVLGPAVDYDRTRSTELLHTVRVLLEHGLDRRAA
MMAR_4951|M.marinum_M               AALAGTDRGHAVAFVRRVLG-PLAANDEGTYRIAATLAVYLEENRSPAKA
TH_4306|M.thermoresistible__bu      LAVLLENPERAKEFAVRELG-PLAADDERSRELRETIRHYLELCSP-KAV
                                      :   :      :    *.  .         :  *:   :        .

MLBr_01052|M.leprae_Br4923          AKRLFTHRNTLLRRIESAEKLLPRPLDH--TSVHIAVALEALQWRGDQTN
MAB_2657c|M.abscessus_ATCC_199      AERLYTHRNTIDRRLARVDELLPKPFAR--NPIEVAAALTLLRVRAGR--
Mb1464|M.bovis_AF2122/97            ADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVL
Rv1429|M.tuberculosis_H37Rv         ADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVL
Mflv_4621|M.gilvum_PYR-GCK          ANELQIHANTVKYRVNRALERRGRPIAA--ERLDVEVALLMCYWLGEVAL
MUL_3452|M.ulcerans_Agy99           AERLHLHYNSVKYRVARAVERRGRPIDD--ERLDVEMALLVCQWFGAVVP
MSMEG_6492|M.smegmatis_MC2_155      ATRLVIHPNTVAQRLRRIESLCSVTLTDPAVILQFSAALTVYDIAALD--
Mvan_5765|M.vanbaalenii_PYR-1       AQALHLHPNTVAQRVRRLEELTGLSLARPADLLRLTAALTVSRIASLS--
MMAR_4951|M.marinum_M               AQRLGVHPNTVSYRVHQAEELLGRTIDIGALDLSVALALLPAMRAMTQRS
TH_4306|M.thermoresistible__bu      AERMFLARGTVAYRLRQAEQALERSLSE--RRLQLWTALVLADAIPPVPA
                                    *  :    .::  *:    .     :      . .  **           

MLBr_01052|M.leprae_Br4923          TSGPRAGRNDGVPA
MAB_2657c|M.abscessus_ATCC_199      --------------
Mb1464|M.bovis_AF2122/97            RAKQ----------
Rv1429|M.tuberculosis_H37Rv         RAKQ----------
Mflv_4621|M.gilvum_PYR-GCK          NPTQALGRS-----
MUL_3452|M.ulcerans_Agy99           GPER----------
MSMEG_6492|M.smegmatis_MC2_155      --------------
Mvan_5765|M.vanbaalenii_PYR-1       --------------
MMAR_4951|M.marinum_M               GGEL----------
TH_4306|M.thermoresistible__bu      ER------------