For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4306 | - | - | 100% (427) | - |
M. thermoresistible (build 8) | TH_3090 | - | 1e-39 | 32.23% (363) | PUTATIVE putative conserved protein |
M. thermoresistible (build 8) | TH_3143 | - | 1e-27 | 29.92% (381) | PUTATIVE putative conserved hypothetical protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1464 | - | 4e-22 | 27.49% (331) | hypothetical protein Mb1464 |
M. gilvum PYR-GCK | Mflv_4621 | - | 1e-23 | 26.79% (336) | hypothetical protein Mflv_4621 |
M. tuberculosis H37Rv | Rv1429 | - | 4e-22 | 27.49% (331) | hypothetical protein Rv1429 |
M. leprae Br4923 | MLBr_01052 | - | 9e-19 | 25.85% (294) | hypothetical protein MLBr_01052 |
M. abscessus ATCC 19977 | MAB_2657c | - | 1e-21 | 28.72% (296) | hypothetical protein MAB_2657c |
M. marinum M | MMAR_4951 | - | 8e-30 | 31.91% (329) | hypothetical protein MMAR_4951 |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_6492 | - | 4e-06 | 28.46% (260) | GAF domain-containing protein |
M. ulcerans Agy99 | MUL_3452 | - | 7e-27 | 28.35% (395) | hypothetical protein MUL_3452 |
M. vanbaalenii PYR-1 | Mvan_5765 | - | 4e-06 | 27.78% (252) | transcriptional regulator, CdaR |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_01052|M.leprae_Br4923 -----------------------------------------MARQHPSPR MAB_2657c|M.abscessus_ATCC_199 -------------------------MNEGSERVHTQSMTPDQLWPDASEP Mb1464|M.bovis_AF2122/97 -----------------------------------MAEAG-------GGP Rv1429|M.tuberculosis_H37Rv -----------------------------------MAEAG-------GGP Mflv_4621|M.gilvum_PYR-GCK -----------------------------------MLDSSEVQDTP-GHA MUL_3452|M.ulcerans_Agy99 -----------------------------------MAERNRTDDAVVGKI MSMEG_6492|M.smegmatis_MC2_155 ------------MTWLGALRRLSASATAEEDLSHVLAEIAETARSLLGFD Mvan_5765|M.vanbaalenii_PYR-1 MSSRTLSTALPFEHWLSALAEIGEAVGGDEPVAEVLDRVARTACTLLGYD MMAR_4951|M.marinum_M -------------------------------------------------- TH_4306|M.thermoresistible__bu -----------------------MSYEGAWMSGLRPRSTPTVAAASPEPA MLBr_01052|M.leprae_Br4923 VRELIREGARIALNPTQEWIDQLDRATFAAN-----------------PA MAB_2657c|M.abscessus_ATCC_199 VRRLIRELAEKMLARSGEVAGDLTAASLEDPRY---------------RT Mb1464|M.bovis_AF2122/97 ISVIARHMQLIRDDFISELFDKMKAEIRGLD------------------- Rv1429|M.tuberculosis_H37Rv ISVIARHMQLIRDDFISELFDKMKAEIRGLD------------------- Mflv_4621|M.gilvum_PYR-GCK VHHLFRDLGDLVRELPESIHGLLIEQVAELA------------------- MUL_3452|M.ulcerans_Agy99 VVEVVYRLSAQLAEATASIQGTLEREIVELR------------------- MSMEG_6492|M.smegmatis_MC2_155 FCGVLLPDEQSRHLRVRGASGLSSDYVDRVNSDRPLVLHGG----SPSSR Mvan_5765|M.vanbaalenii_PYR-1 FCAVFLPDEQGRALTIEGSYGLSADYIAQVNANRPILLDVRGDHEAPTSL MMAR_4951|M.marinum_M -------MQTCATQLARDIVDRYQSELPSIVP------------------ TH_4306|M.thermoresistible__bu VQWARRVAGDGPVDWAVEHAYEFALHVLQEIP------------------ MLBr_01052|M.leprae_Br4923 IANDPVLAKVVRRASRAHLVHWATANLRDPGAPVPAHLG----------- MAB_2657c|M.abscessus_ATCC_199 IADDPVIAEVDARLTVSNLKHWLTSNISEPGHRVRPATG----------- Mb1464|M.bovis_AF2122/97 --YDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP------------ Rv1429|M.tuberculosis_H37Rv --YDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP------------ Mflv_4621|M.gilvum_PYR-GCK --ADQQLKELLSDTVAANVDTWFSVVRHSIPFDRMESP------------ MUL_3452|M.ulcerans_Agy99 --GDVQLLDLLHASVEGNVAAVLNAIHYDIPIERVESP------------ MSMEG_6492|M.smegmatis_MC2_155 AFHTAEAVAIRDVTAEPGFELWAGIANEQGYRSMIAVPLVARGEVLGTLN Mvan_5765|M.vanbaalenii_PYR-1 AYRTGDVVTLEDIELVPDFT-WGGVAQEQGYRALISAPLRRPGTVVGALN MMAR_4951|M.marinum_M ---DPPAVADQLASVEASVRQIAECIDSGEGPRLLDLT------------ TH_4306|M.thermoresistible__bu -ELDGTGGRTRMVRVGAEACVLQVLMLLFDDRSDVEMP------------ MLBr_01052|M.leprae_Br4923 ---PEPLTMARDLVR----------------------RGRDVLALD-IYR MAB_2657c|M.abscessus_ATCC_199 ---SAMRTYARDVVL----------------------RGLTTDDIQ-SWR Mb1464|M.bovis_AF2122/97 ---AAALAYARAAAQ----------------------RDIPLSGLVRAHR Rv1429|M.tuberculosis_H37Rv ---AAALAYARAAAQ----------------------RDIPLSGLVRAHR Mflv_4621|M.gilvum_PYR-GCK ---TAALEHARRMAQ----------------------REVPVNALLRAYR MUL_3452|M.ulcerans_Agy99 ---TAALEYARRLAQ----------------------RGVPVNALVRAYR MSMEG_6492|M.smegmatis_MC2_155 GYYGAVHTYTRFEVERMTLLANHAAIAVSSARRLDELRALTASLRRQRDA Mvan_5765|M.vanbaalenii_PYR-1 GYRTAPHRFDRAEVSLVTTLATQVAIALGTA----QLRAKEQATIR---E MMAR_4951|M.marinum_M ---PATAAIGRSGVQ----------------------RNIALNDLFRSVR TH_4306|M.thermoresistible__bu ---DEQEQVVRDCVH----------------------RKVPLDRLFSAIR * . * MLBr_01052|M.leprae_Br4923 VGQYTAWRRWMEIAFTLTSDPQELREILNVSAQSINEYVAATLEAIA--- MAB_2657c|M.abscessus_ATCC_199 AVQRVGWKWWLAACFQVTDDKEQLCELIEVTSNSLTTFVDDSIAELA--- Mb1464|M.bovis_AF2122/97 LGHARFLEVAMQ--YVSLLEPADRVSTIIELVNRSARLVDLVADQLI--- Rv1429|M.tuberculosis_H37Rv LGHARFLEVAMQ--YVSLLEPADRVSTIIELVNRSARLVDLVADQLI--- Mflv_4621|M.gilvum_PYR-GCK LGHQYGLNLIIAGLRSADLPPEEKLALIEHITRVSFRYIDWMSEQVL--- MUL_3452|M.ulcerans_Agy99 LGHKEMLERIIDGVQEAGADPALSLDVFNRISEVTFNYIDWISQQVV--- MSMEG_6492|M.smegmatis_MC2_155 LTRSEQIHDRLLAVTLRSGGLDGIAAVLQGLIGRPILIDDIQHEVLACSV Mvan_5765|M.vanbaalenii_PYR-1 LRRAEEVHTLLTATALRGEGVSGVAAALSELLGRGVLIEDVYDEPLT--- MMAR_4951|M.marinum_M MAQERTWQWLFDRITASS-AATDHDRALDLATNWLFGYVDVVLIRAER-- TH_4306|M.thermoresistible__bu NTHAWVTRIFMDACIELAPPSQQ-VAELRRISSITLAVFDRYTERAD--- : . : : MLBr_01052|M.leprae_Br4923 ---------------------------------------------THMQL MAB_2657c|M.abscessus_ATCC_199 ---------------------------------------------EHVRR Mb1464|M.bovis_AF2122/97 ---------------------------------------------VAYEH Rv1429|M.tuberculosis_H37Rv ---------------------------------------------VAYEH Mflv_4621|M.gilvum_PYR-GCK ---------------------------------------------ETYQT MUL_3452|M.ulcerans_Agy99 ---------------------------------------------AAYEA MSMEG_6492|M.smegmatis_MC2_155 VTTDFPDTTWRAAAEAGTGSSPVPVGQFDGTTYLASAVHLGDEVAARIWF Mvan_5765|M.vanbaalenii_PYR-1 ------DANWTAPDPR-------------AQDHVVATVTLDGSPVARIHV MMAR_4951|M.marinum_M ----------------------------------------------LYEV TH_4306|M.thermoresistible__bu ---------------------------------------------VAYRA MLBr_01052|M.leprae_Br4923 ERDELTRSTHAERLEVVDLILEGAPVTQERAEARLGYRLG-LTHTAAVIW MAB_2657c|M.abscessus_ATCC_199 VREELAGGSQLQRYATVELLLQGADIAPARAEAQLGYALT-GSHIGAVVW Mb1464|M.bovis_AF2122/97 EHDRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRLD-GVHIAAVVW Rv1429|M.tuberculosis_H37Rv EHDRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRLD-GVHIAAVVW Mflv_4621|M.gilvum_PYR-GCK ERAEWDERRRSLRAQAIRDILNGRDVDLTEASSAMRYFLG-ATHVALMVW MUL_3452|M.ulcerans_Agy99 ERDRWLENRSRVRNVRIAEILDGGDIDTDAMTKSIRYPLR-KVHLALVLW MSMEG_6492|M.smegmatis_MC2_155 PETSIDLDPIMVRAVEHASIVTALELLRCQTAAEVEQRLR-GELLSDVLS Mvan_5765|M.vanbaalenii_PYR-1 AASDSELSRLDVRAVEHATVVTALELLRARTAAEVEQRIR-GSLVADLLS MMAR_4951|M.marinum_M EREAWLTGAAAARAAAVEDILTEREDDAQRASTRLRYDVN-RHHVGVSVW TH_4306|M.thermoresistible__bu EAERWFAGDQATREELVQTLLTRDDADTDRISQRLRYPVTGRNHLGVVAW : :: : : . MLBr_01052|M.leprae_Br4923 SDDLDGDHGYLDQAAEAFSHVVE--------------------------- MAB_2657c|M.abscessus_ATCC_199 VDSEK-EIAALERASEQVMRACG--------------------------- Mb1464|M.bovis_AF2122/97 VDSAV-PIGDVVAQFDQVRCLLAGELGP---------------------- Rv1429|M.tuberculosis_H37Rv VDSAV-PIGDVVAQFDQVRCLLAGELGP---------------------- Mflv_4621|M.gilvum_PYR-GCK LDRDAGADTDEFIAMERFMQHAVSATG----------------------- MUL_3452|M.ulcerans_Agy99 FPDDA-TDGNEFERLERFLDELAEHLG----------------------- MSMEG_6492|M.smegmatis_MC2_155 SGAAL--SDRLLDRAHRLGHDLTVPHIAIVGAFTGLDPVAERRAYERSLV Mvan_5765|M.vanbaalenii_PYR-1 SDDAG--IPALLDRARRLGWDLSG-----VQSLIALRPADER-----TLA MMAR_4951|M.marinum_M RDVTQDACAGPVTLTEALTQLTRAIAAQ---------------------- TH_4306|M.thermoresistible__bu REAGTDAADDLAEAAAAWLRAAG--------------------------- MLBr_01052|M.leprae_Br4923 ---------STQQLIVVASAATRWVWLADALALDVPEVQKALLNLS---K MAB_2657c|M.abscessus_ATCC_199 ---------ADRRLTVVAGTVALWLWIPAKTTPTVAVLMDSLGRRS---G Mb1464|M.bovis_AF2122/97 -----ELGPVANSLMVPTDEREARLWFSPAPTRAFAPSRIRAAFESAGIR Rv1429|M.tuberculosis_H37Rv -----ELGPVANSLMVPTDEREARLWFSPAPTRAFAPSRIRAAFESAGIR Mflv_4621|M.gilvum_PYR-GCK ---------AKQSVYFSIDRLVGCAWMTVHRPSDYLS-QLRDFVRAQPDG MUL_3452|M.ulcerans_Agy99 ---------TGNALFVAADRITGWGWIPLRANDAGLTGRVRRFVAGHTDA MSMEG_6492|M.smegmatis_MC2_155 LLAKESAAHRPKPVVAMHAGTIVMLWPAQDAADAAGAGEVVRQAMRAASA Mvan_5765|M.vanbaalenii_PYR-1 AADRFTAGVTPHPLVALHRGDLVFVWPA-DTGPAVPVAHRLLEFLNAATI MMAR_4951|M.marinum_M ---------SVLAHPAGSKAIAGWLSRPQAFTAAELDVANICSGIHLPQD TH_4306|M.thermoresistible__bu ---------AAEVLVLNRAESAVWAWGATPSPP-----RSVPTDWTHSGG . MLBr_01052|M.leprae_Br4923 ARVAIGTSSAGIEGFRRSHLEALTAQRTLARLKSHQQ--VAFFAD--VQL MAB_2657c|M.abscessus_ATCC_199 VRVALGRAATGMAGFRRTHMDAAAAQRLLARLGSPLS--VVRYED--VHL Mb1464|M.bovis_AF2122/97 ARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD--VAP Rv1429|M.tuberculosis_H37Rv ARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD--VAP Mflv_4621|M.gilvum_PYR-GCK PRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARDPGVAL MUL_3452|M.ulcerans_Agy99 PHVALGQALPGVEGFRRAHRQARNAHRVGVAV-GASAPAVMAVSDEGLSA MSMEG_6492|M.smegmatis_MC2_155 DRQATVAVGPGDVASHR-ESYQTAKGALQVAIMSGRTAAVVGLDDLGIAG Mvan_5765|M.vanbaalenii_PYR-1 PEAPTAAVSRQAAARELPGIFRTVRGALDLAGDR-DTATVIDLDEPTIDH MMAR_4951|M.marinum_M VRVAIGEPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN--VAV TH_4306|M.thermoresistible__bu VRIGHGTWHPGLQGFRLTHREARSAEHVAHLCPRIDS-RVVDYRG--VDL . . . : : MLBr_01052|M.leprae_Br4923 VSLITQNPEDAKEFITSTLG-DFESAS---PALQQTLLTFINEQCNASRA MAB_2657c|M.abscessus_ATCC_199 MDLLSADPASADQFVTDVLG-EFQSAS---PVLHQTVLTYVEEALNRTST Mb1464|M.bovis_AF2122/97 VALLADDLEELRRFVTDVLG-DLSVDDERNSWLRETLREFLLRNRSYVAT Rv1429|M.tuberculosis_H37Rv VALLADDLEELRRFVTDVLG-DLSVDDERNSWLRETLREFLLRNRSYVAT Mflv_4621|M.gilvum_PYR-GCK ASMLMTDDATLKEWIHDVLG-PLAQNTASDQRLRDTLRVFLRAGSSFKAA MUL_3452|M.ulcerans_Agy99 AALMGADLPDAGAWVRETLG-PLSTDSDNDAVLRETLRVFLREGGSYKAA MSMEG_6492|M.smegmatis_MC2_155 LLLRINDPAALSTFARRTLAPILDYDHAHRTELLVTLRAYLECRQERSAT Mvan_5765|M.vanbaalenii_PYR-1 LLLQLDDPARLRDFASAVLGPAVDYDRTRSTELLHTVRVLLEHGLDRRAA MMAR_4951|M.marinum_M AALAGTDRGHAVAFVRRVLG-PLAANDEGTYRIAATLAVYLEENRSPAKA TH_4306|M.thermoresistible__bu LAVLLENPERAKEFAVRELG-PLAADDERSRELRETIRHYLELCSP-KAV : : : *. . : *: : . MLBr_01052|M.leprae_Br4923 AKRLFTHRNTLLRRIESAEKLLPRPLDH--TSVHIAVALEALQWRGDQTN MAB_2657c|M.abscessus_ATCC_199 AERLYTHRNTIDRRLARVDELLPKPFAR--NPIEVAAALTLLRVRAGR-- Mb1464|M.bovis_AF2122/97 ADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVL Rv1429|M.tuberculosis_H37Rv ADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVL Mflv_4621|M.gilvum_PYR-GCK ANELQIHANTVKYRVNRALERRGRPIAA--ERLDVEVALLMCYWLGEVAL MUL_3452|M.ulcerans_Agy99 AERLHLHYNSVKYRVARAVERRGRPIDD--ERLDVEMALLVCQWFGAVVP MSMEG_6492|M.smegmatis_MC2_155 ATRLVIHPNTVAQRLRRIESLCSVTLTDPAVILQFSAALTVYDIAALD-- Mvan_5765|M.vanbaalenii_PYR-1 AQALHLHPNTVAQRVRRLEELTGLSLARPADLLRLTAALTVSRIASLS-- MMAR_4951|M.marinum_M AQRLGVHPNTVSYRVHQAEELLGRTIDIGALDLSVALALLPAMRAMTQRS TH_4306|M.thermoresistible__bu AERMFLARGTVAYRLRQAEQALERSLSE--RRLQLWTALVLADAIPPVPA * : .:: *: . : . . ** MLBr_01052|M.leprae_Br4923 TSGPRAGRNDGVPA MAB_2657c|M.abscessus_ATCC_199 -------------- Mb1464|M.bovis_AF2122/97 RAKQ---------- Rv1429|M.tuberculosis_H37Rv RAKQ---------- Mflv_4621|M.gilvum_PYR-GCK NPTQALGRS----- MUL_3452|M.ulcerans_Agy99 GPER---------- MSMEG_6492|M.smegmatis_MC2_155 -------------- Mvan_5765|M.vanbaalenii_PYR-1 -------------- MMAR_4951|M.marinum_M GGEL---------- TH_4306|M.thermoresistible__bu ER------------